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JPS617173B2 |
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JPS6143137A |
PURPOSE: To produce the titled substance in high yield, without producing high- boiling compounds, by carrring out the carbonylation reaction of an alkenylnorbornene, etc. with carbon monoxide and water, etc. in the presence of a catalys...
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JPS60258141A |
PURPOSE: To obtain the titled compound with a high trans-content useful as an intermediate for liquid crystals, by heating an alkali or alkaline earth metal salt of a mixture of the cis- with the trans-isomers of the titled compound in a...
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JPS60258137A |
2,2-Dimethyl-3-formylcyclopropanes of the formula in which R<1> and R<2> represent CN, COC1-4-alkyl, CO-halogen or COOC1-4-alkyl, process for their preparation, novel intermediates for carrying out this process and process for the prepar...
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JPS60252476A |
NEW MATERIAL:A compound expressed by the formula (X is H or Cl). EXAMPLE: 2,2-Dichloro-3-(2-chloro-2-methylethyl)-4-hydroxybutyrolacto
ne. USE: An intermediate for preparing cis-chrysanthemumic acid. PREPARATION: Prenyl alcohol expressed...
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JPS6056125B2 |
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JPS60246383A |
Tetrahydrofuranyl substituted ethers are provided having the structural formula wherein A is (CH2)2, CH=CH or a single bond, m is 1 to 5, B is a single bond or CH=CH, n is 1 to 4, X is O or wherein n' is 0, 1 or 2, R is H, lower alkyl or...
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JPS6055497B2 |
Aliphatic and cycloaliphatic alpha -ketocarboxylic acids of the formula I are prepared by hydrolysing (saponifying) acyl cyanides of the formula II to carboxamides of the formula III, the substituents R, R1 and R2 being as defined in Cla...
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JPS6054942B2 |
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JPS6054285B2 |
The chemical compounds of the invention are useful as the active compound in drugs because of their anticonvulsant and/or antianoxic activity. They have the general formula wherein Z is a hydroxyl group; a group-OM wherein M is an alkali...
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JPS60233037A |
(57) [Abstract] Since this gazette is application data in front of an electronic application, the data of an abstract is not recorded.
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JPS60228414A |
PURPOSE: To provide the titled remedy containing tropolone or its derivative as an active component. CONSTITUTION: The objective preventive or remedy for the diseases caused by the metabolic product of 12-lipoxygenase is prepared by usin...
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JPS60202880A |
Compounds of formula (I): wherein n is 1 or 2, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of malaria are disclosed.
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JPS60132928A |
(57) [Abstract] Since this gazette is application data in front of an electronic application, the data of an abstract is not recorded.
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JPS6029713B2 |
This disclosure describes novel 2,5-dihydro-2,5-dialkoxyfuran derivatives useful as intermediates for the preparation of the natural prostaglandins and their congeners.
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JPS6024781B2 |
A known effective choleretic, cis-2-hydroxy-2-phenyl-r-1-cyclohexane carboxylic acid is obtained with a novel method wherein 1-phenylcyclohexene is reacted with formaldehyde in formic acid or mixture of formic acid with other solvents. T...
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JPS6021574B2 |
The (+), (-) and (+/-) forms of the compounds of formula I I wherein R1 is hydrogen or a methoxy, ethoxy, propoxy, methylthio, ethylthio, propylthio, fluoro, chloro, bromo, methyl, ethyl, nitro or amino group, and R2 is a hydrogen or met...
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JPS6020371B2 |
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JPS6020370B2 |
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JPS6012341B2 |
PURPOSE:To obtain indane derivatives useful as analgesics, antiphlogistics, antipyretics, etc., with ease in short process with high yields, by reacting indanone derivatives with sulfonylmethylisonitrile derivatives and then hydrolyzing ...
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JPS609754B2 |
The disclosure relates to a series of novel prostaglandin intermediates, the preparation of which in sequence constitutes a novel process for the manufacture of known diol intermediates, for example 2,3,3a beta ,6a beta -tetrahydro-5 alp...
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JPS609035B2 |
The disclosure relates to a series of novel prostaglandin intermediates, the preparation of which in sequence constitutes a novel process for the manufacture of known diol intermediates, for example 2,3,3a beta ,6a beta -tetrahydro-5 alp...
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JPS606933B2 |
Compounds of the general formula I (I) wherein one of the two radicals R1 and R2 denotes the acyl radical of a carboxylic acid of aromatic character and the other denotes hydrogen or optionally esterified or etherified hydroxyl, R3 denot...
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JPS602293B2 |
The present invention provides new glycyrrhetinic acid derivatives of the general formula: wherein R is an alkylene or cycloalkylene radical and X represents an oxygen atom or two hydrogen atoms; and the non-toxic salts and esters thereof.
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JPS59196837A |
Pesticidally active 2,2-dimethyl-3-(2-halogeno-vinyl)-cyclopropanecarboxylic acid esters of the formula in which R1 and R2 are identical or different and represent alkyl or halogenoalkyl, R3 represents alkyl or the grouping -(CH2)-nR4, i...
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JPS5940815B2 |
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JPS59157042A |
Racemic endo- and exo-1-methoxybicyclo[2.2.2]oct-5- ene-2-carboxylic acids are starting materials for a novel and efficient synthesis of chiral 3R-[2-hydroxy-4-(1,1-dimethylheptyl)phenyl]-4R-(3-hydroxypro
pyl)-1R-cyclohexanol, a compound...
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JPS5930696B2 |
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JPS5929177B2 |
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JPS59122427A |
PURPOSE: To provide the titled preventive and remedy containing a specific cyclic compound as an active component, and capable of remarkably suppressing the contraction of the basilar vessel caused by oxyhemoglobin. CONSTITUTION: The obj...
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JPS5928397B2 |
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JPS5921858B2 |
The (+), (-) and (+/-) forms of the compounds of formula I I wherein R1 is hydrogen or a methoxy, ethoxy, propoxy, methylthio, ethylthio, propylthio, fluoro, chloro, bromo, methyl, ethyl, nitro or amino group, and R2 is a hydrogen or met...
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JPS5980620A |
Compounds of general formula (I):wherein R is a chlorine, bromine or Iodine atom and physiologically acceptable salts thereof with bases of use as antiviral agents.
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JPS5973541A |
PURPOSE: To subject d,l-bicyclo(3,3,0)octanecarboxylic acid derivative useful as an intermediate for methanocyclin derivative (remedy for alleviating thrombosis) efficiently and easily, by using an optically active arylalkylamine. CONSTI...
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JPS5917096B2 |
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JPS5917097B2 |
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JPS5912097B2 |
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JPS599536B2 |
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JPS5931773A |
PURPOSE: To prepare the titled substance useful as a synthetic intermediate of pharmaceuticals, in high yield, by protecting the hydroxyl group of a specific compound, e.g. (1S, 2R, 3R, 5R)-2-carboxy-3-hydroxy-7,7-ethylenedioxy-bicyclo [...
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JPS595568B2 |
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JPS593462B2 |
1470189 Preparation of bicycloalkane derivatives SCHERING AG 10 April 1974 [18 April 1973 25 Feb 1974] 15906/74 Heading C2C Bicycloalkane derivatives of formula in which n represents 1 or 2, R represents -CH 3 or -C 2 H 5 group, and X an...
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JPS5910548A |
NEW MATERIAL:Pfaffic acid and its derivative of the formula (R1 is H or acyl; R2 is H or alkyl). USE: An antitumor agent, capable of exhibiting improved inhibitory activity against melanoma cells, cervical cancer cells, cancer cells of t...
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JPS58219142A |
A process for the preparation of 2,2-dimethyl-3-arylcyclopropanecarboxylic acid or ester of the formula in which Ar is naphthyl or the radical R1 is H or C1-C4-alkyl, Z is oxygen, sulphur, or 1,2-ethenediyl, and R2 represents hydrogen, h...
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JPS58219141A |
2,2-Dimethyl-3-arylcyclopropanecarboxylic acids and esters, suitable as insecticide intermediates, of the formula (I) in which Ar is naphthyl or substituted furyl, thienyl or phenyl, and R1 is hydrogen or alkyl, are produced by subjectin...
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JPS58213731A |
A series of ester and salt derivatives of fluorene-9-carboxylic acid and fluorene-1-carboxylic acid exhibit significant plant growth regulating properties, useful in controlling the size, shape, dormancy time, flowering time and/or fruit...
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JPS58201713A |
The invention provides oleanolic acid and/or a physiologically acceptable salt thereof for use in treating a patient prophylactically and/or therapeutically for ulcerogenic-type disorders of the stomach and/or intestines. The ulcerogenic...
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JPS58192845A |
NEW MATERIAL:A bicyclo [3.3.0] octane derivative expressed by formula I [A is oxo or OH which may be protected; B is protected carboxy, hydroxymethyl, formyl or formula II (R1 is alkyl or alkenyl; D is oxo or OH); Z is a protecting group...
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JPS5844650B2 |
1476153 Oxo-carboxylic acids HOECHST AG 27 Sept 1974 [27 Sept 1973] 42044/74 Heading C2C 5-Oxo carboxylic acids of formula wherein R 1 and R 2 which may be the same or different represent a substituted or unsubstituted alkyl, cycloalkyl,...
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JPS5842178B2 |
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JPS5840534B2 |
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