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WO/2012/016367A1 |
Trehalose derivatives shown as the general formula (I), preparation methods and uses thereof in the manufacture of medicines for preventing and treating invasion and metastasis of colon cancer 26-L5 cells are disclosed, wherein R is defi...
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WO/2012/013127A1 |
Nucleotide and/or oligonucleotide represented by formula (1) and the liquid phase synthesis process thereof. The present invention provides a liquid phase synthesis process for preparing a nucleotide and/or an oligonucleotide, comprising...
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WO/2012/012465A1 |
Provided are methods and intermediates for preparing diastereomerically pure phosphoramidate prodrugs of nucleosides of Formulas (la) and (lb): The compounds of Formula la and lb are useful for the treatment Hepatitis C infections.
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WO/2012/012734A2 |
A system and method for hardwood pulp liquid hydrolysate conditioning includes a first evaporator receives a hardwood mix extract and outputting a quantity of vapor and extract. A hydrolysis unit receives the extract, hydrolyzes and outp...
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WO/2012/010749A2 |
The present invention relates to a method for converting lignocellulosic biomass into sugars, comprising at least three steps. The first step is a step of cooking the lignocellulosic biomass in the presence of at least one hydrated inorg...
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WO/2012/010750A2 |
The present invention relates to a method for converting lignocellulosic biomass into sugars, comprising at least three steps. The first step is a step of cooking the lignocellulosic biomass in the presence of at least one hydrated inorg...
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WO/2012/007569A1 |
The present invention pertains to method for purifying at least a target nucleic acid from a sample, said method comprising at least the following steps: a) incubating the sample with at least one protein-degrading compound; b) binding t...
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WO/2012/009315A2 |
Oligosaccharides from bovine milk, whey and dairy products, and methods of producing bovine milk oligosaccharides are provided.
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WO/2012/001126A1 |
A method for synthesizing an oligonucleotide which comprises using a sulfurizing agent of general formula (I) for sulfurizing at least one phosphorus internucleotide linkage of a precursor of the oligonucleotide, wherein R is an aryl gro...
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WO/2011/159949A2 |
This invention relates to degradation of biomass with a peroxide in the presence of a metal catalyst. The process can result in ethanol production from cellulosic biomass, fuel gases, useful chemicals and biochemicals from decomposition ...
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WO/2011/153815A1 |
N-acyl modified sialic acid (α-(2→6)-D-aminopyranose derivatives, their synthesis methods and uses are disclosed. Sialic acid (α-(2→6)-D-aminopyranose derivatives represented by formula (I) are synthesized by using D-aminogalactose...
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WO/2011/153874A1 |
Provided is a crystallization process of cyclic adenosine 3',5'-monophosphate, which comprises the following steps: 1) reacting an aqueous solution of cyclic adenosine 3',5'-monophosphate with a base to obtain a salt of cyclic adenosine ...
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WO/2011/150775A1 |
Disclosed is a method for treating a fermentation liquor of natamycin which is a fungus inhibitor. In this method, protease and lipase are added to the fermentation liquor for enzymolysis. Water insoluble proteins and lipid in filter cak...
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WO/2011/150939A1 |
The present invention relates to novel polymorphs of the trisaccharide 2'-0-fucosyllactose (2-FL) of formula (1 ), methods for producing said polymorphs and their use in pharmaceutical or nutritional compositions.
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WO/2011/145519A1 |
Disclosed are methods for producing a glucoside directly from glucose or a sugar chain comprising glucose as a structural unit. Specifically disclosed are: a method which comprises reacting glucose or a sugar chain comprising glucose as ...
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WO/2011/144213A1 |
The present application discloses a method for the crystallization of fucose, characterized in that the crystallization is carried out from a mixture comprising fucose and at least one 6-deoxy sugar selected from 6-deoxy-talose and 6-deo...
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WO/2011/140676A1 |
The present invention discloses use of Rhizoma Gastrodiae plant extract containing parishin derivative in manufacture of medicaments for preventing and treating Alzheimer disease (AD), vascular dementia (VaD) and mixed type diseases ther...
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WO/2011/137758A1 |
Provided are ketolide derivatives of general formula (I) or (II), or pharmaceutically acceptable salts or esters thereof formed with inorganic acids or organic acids. In the formula, Ar represents aromatic heterocyclic alkyl or substitut...
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WO/2011/130273A2 |
Described herein are oligonucleotides useful for screening, detecting, isolating, quaniitaiing, monitoring and sequencing of viruses and host biomarkers associated with prostate cancer and -methods and kits of using the described oligonu...
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WO/2011/113373A1 |
Disclosed is a method for ultrasonic extraction of stevioside. Crushed dry leaves of Stevia rebaudiana serve as raw material. Based on the characteristic that an ultrasonic cavitation can reinforce the extraction of active ingredients in...
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WO/2011/113173A1 |
The cytarabine prodrug derivatives of general formula (I), their synthetic routes, preparation and preparative method thereof, and use for resisting cancer or tumor. The derivatives are prepared by chemical modification on N4, O5 positio...
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WO/2011/110084A1 |
Method for preparing isovalerylspiramycin I, II or III and pharmaceutical composition containing the compound thereof which has antibacterial activity are provided. Isovalerylspiramycin I, II or III is obtained by the procedures of prima...
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WO/2011/100980A1 |
The present invention relates to a method for preparation of the tetrasaccharide lacto-N-neotetraose (LNnt, formula (I)) especially in large scale, as well as intermediates in the synthesis, a new crystal form (polymorph) of LNnt, and th...
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WO/2011/100979A1 |
The present invention relates to a method for preparation of the trisaccharide 6'-0-sialyllactose (formula (I)) or salts thereof as well as intermediates in the synthesis and for the use of 6'-0-sialyllactose salts in pharmaceutical or n...
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WO/2011/100670A1 |
This invention pertains to a process for manufacturing scyllo-Inositol. Specifically, the current invention pertains to a process for converting myo-Inositol to scyllo-Inositol using a bioconversion process.
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WO/2011/098240A2 |
The present invention relates to a process for an epimerization of a saccharide in a microdevice consisting of a network of micron-sized channels in presence of molybdenum containing catalyst. It further relates to the use of a microdevi...
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WO/2011/095893A1 |
A convenient and scalable synthesis of DGJNAc ID from D-glucuronolactone in an overall yield of 20% is provided. DGJNAc is the first highly potent and specific competitive inhibitor of GalNAcases. DGJNAc ID is also a competitive inhibito...
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WO/2011/088843A1 |
The present invention relates to enterococcal cell wall components and their uses in the prevention and therapy of bacterial infection.
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WO/2011/082288A1 |
Exemplary embodiments of this invention encompass a method for purifying a low purity steviol glycoside composition. In particular, this invention relates to a method for purifying low purity steviol glycoside compositions to obtain subs...
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WO/2011/079501A1 |
Prodrugs based on cytarabine structure shown as formula (I) as well as their synthetic method and application are disclosed, wherein the definitions for the groups of R1 and R2 are described in the specification. The solubility, the bioa...
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WO/2011/076625A1 |
The invention relates to a sweetener and to a method for the production thereof.
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WO/2011/073926A1 |
The invention relates to an amorphous non-crystalline glass form (Form-ll) of 3R, 4S, 5S, 6R, 7R, 9R, 11S, 12R, 13S, 14R-6-[(2S, 3R, 4S, 6R)-4- dimethylamino-3- hydroxy-6-methyloxan-2-yl]oxy-14- ethyl-7, 12, 13- trihydroxy-4-[(2R, 4R, 5S...
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WO/2011/073927A1 |
The invention relates to an amorphous non-crystalline glass form (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R) -2-ethyl-3,4, 10- trihydroxy- 3,5,6,8,10,12,14- heptamethyl-15-oxo- 11- {[3,4,6- trideoxy-3- (dimethylamino) -β-D-xylo- hexopyranosyl]...
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WO/2011/069391A1 |
A method for extracting arabinose from mixed sugar is provided. The mixed sugar comprises arabinose admixed with xylose or rhamnose. Based on the different solubility and crystallinity of arabinose and xylose or rhamnose in organic solve...
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WO/2011/064726A1 |
A method of synthesising Aspalathin and its analogues or derivatives is disclosed. The method comprises synthesising a compound of formula 1 or its analogues or derivatives (I) wherein each of R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10 i...
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WO/2011/060807A1 |
The present invention relates to a novel process for producing N-acetyl-D-Glucosamine from Glucosamine hydrochloride. More particularly this invention pertains to a novel and simple environmentally acceptable process for producing glucos...
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WO/2011/058661A1 |
Provided is a method for extracting isosaponarin at a high concentration from wasabi (Wasabia japonica) leaves. Also provided is a method for extracting a material for foods, drugs and cosmetics. Isosaponarin is extracted at a high conce...
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WO/2011/054289A1 |
Compounds represented by general formula (I), pharmaceutically acceptable salts and solvates thereof or solvates of pharmaceutically acceptable salts are disclosed. wherein R1, R2, R3, R4, W and formula (II) are defined as in the applica...
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WO/2011/044751A1 |
Foliamangiferosides having the general formula (I) are disclosed, wherein R is H or -OCH3. The preparation method of the compounds, pharmaceutical compositions comprising the compounds as the active ingredients, the use of the compounds ...
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WO/2011/046423A1 |
The invention provides methods of purifying Rebaudioside D from the Stevia rebaudiana Bertoni plant extract along with Rebaudioside A. The methods are useful for producing high purity Rebaudioside D and Rebaudioside A. The invention furt...
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WO/2011/043107A1 |
Disclosed is a method for extracting a compound containing sialic acid from a raw material that is readily available and does not has undergo the contamination by any animal-affecting pathogen (i.e., has high safety), wherein the method ...
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WO/2011/038874A1 |
The application describes a one-pot process for releasing and labelling O-glycans from glycoproteins, thereby facilitating analysis via LC-ESI-MS-MS. The process comprises contacting the glycoprotein with an amine, eg. methylamine, dimet...
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WO/2011/037959A1 |
Embodiments of this invention encompass a method for producing and purifying rebaudioside C. In particular, this invention relates to a method for purifying rebaudioside C compositions to obtain a substantially pure rebaudioside C produc...
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WO/2011/035250A1 |
Provided are processes and intermediates for the syntheses of nucleosides of pyrrolo[1,2-f][1,2,4]triazinyl and imidazo[1,2-f][1,2,4]triazinyl heterocycles of Formula I.
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WO/2011/029110A1 |
The invention relates to a method for concentrating a material solution using at least two consecutive membrane separating stages, each for separating the material solution into a retentate and a permeate, the cut-off of the membranes us...
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WO/2011/028218A1 |
The present invention describes simple, efficient, and enzyme-free method of making oligonucleotides with 5'-triphosphate. This invention presents novel process for synthesizing triphosphate oligonucleotides using a diaryl phosphonate as...
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WO/2011/027790A1 |
Provided is a powder containing anhydrous crystals of ascorbic acid 2-glucoside, said powder being significantly less prone to caking than existing general-purpose quasi-drug-class powders containing anhydrous crystals of ascorbic acid 2...
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WO/2011/025286A2 |
The present invention relates to lipoteichoic acid-derived glycolipids, and to pharmaceutical, food or cosmetic compositions and vaccine adjuvants comprising same. The lipoteichoic acid-derived glycolipids according to the present invent...
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WO/2011/023755A1 |
A process for preparing pyrazole-glycoside derivatives of the general Formula (I) in which the meanings are R1 H and R2 F; or R1 F and R2 H; or R1 F and R2 F; R3 (C1-C8)-alkyl, where one, more than one or all hydrogen(s) may be replaced ...
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WO/2011/011907A1 |
A preparation method of D-glucosamine hydrochloride originated from plant is disclosed, which comprises using waste hypha residue of citric acid as initial raw material, acidolyzing the waste hypha residue with hydrochloric acid, condens...
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