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Matches 1 - 50 out of 3,647

Document Document Title
WO/2019/169496A1
Provided herein are methods of treating constipation in subjects in need thereof. The method includes administering a therapeutically effective dosage of N-acetylglucosamine. Subjects who may benefit from treatment include those having s...  
WO/2019/154195A1
The present invention relates to a novel therapeutic drug for a neurodegenerative disease and an application thereof. Provided is a novel compound of formula (I). The compound can effectively facilitate the proliferation of neural stem c...  
WO/2019/154306A1
Disclosed in the present invention are saccharide derivatives for immune cell surface modification and use thereof. The saccharide derivatives of the present invention are 9-position or 5-position target substituent modified 9-carbon mon...  
WO/2019/151128A1
A cell labeling agent according to the present invention includes a monosaccharide derivative having a six-membered ring structure metabolized by sialic acid in a sialic acid biosynthesis pathway of a cell. Among groups bonded to carbon ...  
WO/2019/053700A3
Probe embodiments for identifying analytes involved in biofuel or bioenergy production, bioremediation, or nutrient cycling as well as methods of making and use are described herein. In some embodiments, probes identifying cellulose degr...  
WO/2019/145562A1
The present invention relates to anew class of sialyltransferase inhibitors. The class features a carbamate or similar moiety on the amine of a neuraminic acid derivative. Such inhibitors are suitable for use as a medicament, for example...  
WO/2019/128410A1
The present invention relates to the preparation of various xylan esterification products, and an application thereof in a drug for preventing, alleviating and/or treating inflammatory diseases. The application of a xylan esterification ...  
WO/2019/119117A1
There are provided compounds of Formula (A) and pharmaceutically acceptable salts and esters thereof, and pharmaceutical compositions thereof, used for the prevention or treatment in a mammal of joint and bone disorders such as arthritis...  
WO/2019/109300A1
Improved enrichment methods for preparing tannic acid compositions that have superior potency in inhibiting D-amino acid oxidase, and superior purity and safety profiles. The tannic acid compositions (e.g., pharmaceutical compositions, n...  
WO/2019/101489A1
The present invention describes an efficient way to isolate a sialic acid from a fermentation broth. The sialic acid contained in the fermentation broth is produced by bacterial fermentation. The inventive process comprises a step of rem...  
WO/2019/092572A1
The present invention relates to new synthetic molecules with agonist activity of human Toll-like Receptor 4 (TLR4), compositions comprising them and uses thereof for the treatment of diseases in which it is useful to induce or increase ...  
WO/2019/088855A1
The invention relates to branched trehalose glycolipids of Formula (I) and their uses. These compounds are potent Mincle agonists and Th1-stimulating vaccine adjuvants.  
WO/2019/088854A1
The invention relates to brartemicin analogues of Formula (IV) and their uses. These compounds are potent Mincle agonists and Th1-stimulating vaccine adjuvants.  
WO/2018/045248A8
The present invention describes tunable methods of treating cellulosic materials with a composition that provides increased hydrophobicity and/or lipophobicity to such materials without sacrificing the biodegradability thereof. The metho...  
WO/2019/063955A1
The present invention concerns the compounds of the following formula (I): (I) in which: - X represents an oxygen atom, a sulfur atom, a nitrogen atom or a CH radical, - The X--Y bond and Y are absent if X represents an oxygen or sulfur ...  
WO/2019/053700A2
Probe embodiments for identifying analytes involved in biofuel or bioenergy production, bioremediation, or nutrient cycling as well as methods of making and use are described herein. In some embodiments, probes identifying cellulose degr...  
WO/2019/049044A1
A glycoside compound of fatty acids that comprises the general formula: GalNAc-GalNAc-Glc-O-R, where GalNAc is a- or β-D-N-acetylgalactosamine, Glc-O-R is a molecule of a- or β-D-glucose esterified to a monounsaturated fatty acid (R), ...  
WO/2019/002594A1
The present invention discloses a method for separating chromatographically indistinguishable 1,2-diaxial from 1,2- diequatorial disaccharide 2-azido-1-nitrates, wherein the disaccharide is a 1→4 disaccharide, comprising the steps of -...  
WO/2018/221562A1
According to the present invention, it is found that dopamine D2-like receptor agonists acts on a dopamine D2-like receptor in an activated Th cell and thereby inhibits the production of Interleukin-8 (IL-8).  
WO/2018/205009A1
Processes for the preparation of phosphorylated heptose compounds are provided. Embodiments of the invention relate to the chemical synthesis of heptopyranose phosphate compounds. Also, embodiments of the invention relate to the use of c...  
WO/2018/204302A1
The present disclosure relates to phosphorylated hexaacyl disaccharide (PHAD) compounds, compositions, and methods for treating or preventing infections.  
WO/2018/181872A1
This resist composition contains at least one type of tannin compound selected from the group consisting of a tannin containing at least one crosslinkable reactive group in the structure, a derivative of said tannin, and a resin obtained...  
WO/2018/166159A1
Disclosed are a Pezicula sp. SC1337 strain and a method for preparing trisaccharide ester derivatives using same. The preservation number of Pezicula sp. SC1337 is GDMCC No: 60144. Pezicula sp. SC1337 can be obtained by means of separati...  
WO/2018/166158A1
Disclosed are a fungal trisaccharide ester compound and an application thereof in preparation of medicines for preventing and controlling plant fungus diseases. (Pezicula sp.) SC1337 can be separated from endophytes in branches of Taxodi...  
WO/2018/170420A1
Provided herein are compositions comprising lipotechoic acid (LTA) and methods of use thereof for immune modulation. In particular, compositions comprising S. epidermidis lipotechoic Acid (SELTA) are provided, as well as method of use th...  
WO/2018/155051A1
Provided is lipid A, which has a novel structure. More specifically, provided is lipid A which can be used in an adjuvant, and with which side effects such as allergic reaction and inflammation are reduced, while maintaining an excellent...  
WO/2018/149359A1
The present invention provides a triazole antibacterial derivative and a pharmaceutical composition and a use thereof, and in particular relates to a compound represented by the following formula (I), and a racemate, a stereoisomer, a ta...  
WO/2018/129603A1
Process for producing a rhamnolipid produced by Pseudomonas or Enterobacter using andiroba or murumuru seed waste, pertaining to the sector of compounds containing monosaccharide radicals, consists of producing rhamnolipids by a biotechn...  
WO/2018/086330A1
The present invention discloses a method for preparing sucralose-6-acylate in a biphasic liquid-liquid system. The method comprises slowly dropwise adding an inert non-polar solvent containing a chlorinating agent to an N,N-dimethyl form...  
WO/2018/074926A1
The present invention relates to new bi-functional and polyfunctional bis- dioxolanes and bis-dioxanes. The present inventors have established that the bis- dioxolanes and bis-dioxanes of the invention are highly advantageous as building...  
WO/2018/068090A1
The present invention relates generally to the field of glycanics and its application to the generation of glycoconjugates for therapeutic use. The present invention also relates to process for the preparation of glycoconjugates.  
WO/2018/067730A1
The present invention provides a method of treating sepsis in a subject, comprising administering to the subject an effective amount of a compound of the formula wherein R1 and R2 may be H, OH, protonated phosphate, a phosphate salt, a s...  
WO/2018/045997A1
The present application falls within the field of drug synthesis, and relates to a method for preparing 2-fluoro-2-methyldeoxynucleoside as an intermediate of Sofosbuvir. In particular, the present application provides a method for prepa...  
WO/2018/045248A1
The present invention describes tunable methods of treating cellulosic materials with a composition that provides increased hydrophobicity and/or lipophobicity to such materials without sacrificing the biodegradability thereof. The metho...  
WO/2018/038103A1
The purpose of the present invention is to provide a process for producing a sugar fatty acid ester such as sucrose fatty acid ester (FASuc) and provide a composition containing the sugar fatty acid ester, the process solving the various...  
WO/2018/033719A1
The invention provides compounds for use in a method of treating and/or preventing a bacterial infection in a human or non-human mammal, said method comprising administration of said compound in combination with (either simultaneously, s...  
WO/2018/028050A1
Disclosed is an asymmetric aryl-alkyl persulfate compound as represented by formula (3) and a synthesis method therefor, in which an arylboronic acid of formula (1) and R2SSCOR3 of formula (2) serve as reaction raw materials and, under t...  
WO/2017/211314A1
Provided herein are a solid substrate comprising an antigen immobilised to said substrate which antigen is capable of binding to an antibody which is indicative for the presence of mycobacterial material in a human or animal, and a metho...  
WO/2017/207754A1
The invention describes novel conjugates of formula (I) of a pharmaceutical agent and a moiety capable of binding to a glucose sensing protein allowing a reversible release of the pharmaceutical agent depending on the glucose concentration.  
WO/2017/195841A1
Provided is a hair pigment enhancer that can act on cells participating in hair pigmentation and thus promote the synthesis of hair pigment to thereby prevent and/or reverse gray hair. A one-pack type hair pigment enhancer that comprises...  
WO/2017/105212A3
The present invention describes a covalent biomaterial which is formed by gelling feruloylated arabinoxylans that are biodegradable and which can be used for the oral administration of insulin directed to the colon. The present invention...  
WO/2017/185900A1
Provided are a series of crocins compounds and related pharmacological application thereof in prevention and treatment of Alzheimer's disease. The series of crocins compounds are obtained by taking the Chinese herb, namely Gardenia jasmi...  
WO/2017/187352A1
The invention relates to a new class of compounds of formula (I) targeting COX-1. The invention also relates to the use of some of such compounds as a tool to investigate the structure and function of the enzyme, in the treatment targeti...  
WO/2017/185899A1
A composition, and a crocins active site extracted from Gardenia jasminoides Ellis, mainly comprising the following ingredients: crocetin di-β-D-gentiobioside, crocetin-β-D-glucopyranosyl-β-D-gentiobioside, crocetin di-β-D-glucopyran...  
WO/2017/177896A1
Disclosed in the present invention are a compound represented by formula (I), a geometric or optical isomer, a pharmaceutically acceptable salt, a solvate or a polymorph thereof. Also disclosed in the present invention is a composition o...  
WO/2017/167168A1
Compositions (e.g., pharmaceutical compositions, nutraceutical compositions or medical food compositions) comprising tannic acids, particularly tannic acids having more than three galloyl moieties, methods of preparing such, and uses the...  
WO/2017/173024A1
The present invention is directed to novel products, variants, pharmaceutically acceptable salts and prodrugs thereof, and medical use of such compounds for the treatment and/or management of sepsis, septicemia, septic shock, ocular infe...  
WO/2017/156432A1
The present disclosure provides edible compositions comprising Formulas and compounds of steviol glycoside esters, or combinations thereof, which are suitable for use as sweeteners, for example, by incorporation into edible compositions....  
WO/2017/123066A1
The present invention relates to a composition for preventing or treating diseases or symptoms associated with a reduction in the expression of peroxisome proliferator-activated receptor coactivator 1-alpha (PGC-1α), the composition con...  
WO/2017/106836A1
A number of triterpene saponin variants with different modifications on their central glycosyl ester linkage are described. Also described are methods of making and method of using such triterpene saponin variants.  

Matches 1 - 50 out of 3,647