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Matches 1 - 50 out of 3,579

Document Document Title
WO/2017/211314A1
Provided herein are a solid substrate comprising an antigen immobilised to said substrate which antigen is capable of binding to an antibody which is indicative for the presence of mycobacterial material in a human or animal, and a metho...  
WO/2017/207754A1
The invention describes novel conjugates of formula (I) of a pharmaceutical agent and a moiety capable of binding to a glucose sensing protein allowing a reversible release of the pharmaceutical agent depending on the glucose concentration.  
WO/2017/195841A1
Provided is a hair pigment enhancer that can act on cells participating in hair pigmentation and thus promote the synthesis of hair pigment to thereby prevent and/or reverse gray hair. A one-pack type hair pigment enhancer that comprises...  
WO/2017/185900A1
Provided are a series of crocins compounds and related pharmacological application thereof in prevention and treatment of Alzheimer's disease. The series of crocins compounds are obtained by taking the Chinese herb, namely Gardenia jasmi...  
WO/2017/187352A1
The invention relates to a new class of compounds of formula (I) targeting COX-1. The invention also relates to the use of some of such compounds as a tool to investigate the structure and function of the enzyme, in the treatment targeti...  
WO/2017/185899A1
A composition, and a crocins active site extracted from Gardenia jasminoides Ellis, mainly comprising the following ingredients: crocetin di-β-D-gentiobioside, crocetin-β-D-glucopyranosyl-β-D-gentiobioside, crocetin di-β-D-glucopyran...  
WO/2017/177896A1
Disclosed in the present invention are a compound represented by formula (I), a geometric or optical isomer, a pharmaceutically acceptable salt, a solvate or a polymorph thereof. Also disclosed in the present invention is a composition o...  
WO/2017/167168A1
Compositions (e.g., pharmaceutical compositions, nutraceutical compositions or medical food compositions) comprising tannic acids, particularly tannic acids having more than three galloyl moieties, methods of preparing such, and uses the...  
WO/2017/173024A1
The present invention is directed to novel products, variants, pharmaceutically acceptable salts and prodrugs thereof, and medical use of such compounds for the treatment and/or management of sepsis, septicemia, septic shock, ocular infe...  
WO/2017/156432A1
The present disclosure provides edible compositions comprising Formulas and compounds of steviol glycoside esters, or combinations thereof, which are suitable for use as sweeteners, for example, by incorporation into edible compositions....  
WO/2017/123066A1
The present invention relates to a composition for preventing or treating diseases or symptoms associated with a reduction in the expression of peroxisome proliferator-activated receptor coactivator 1-alpha (PGC-1α), the composition con...  
WO/2017/105212A3
The present invention describes a covalent biomaterial which is formed by gelling feruloylated arabinoxylans that are biodegradable and which can be used for the oral administration of insulin directed to the colon. The present invention...  
WO/2017/106836A1
A number of triterpene saponin variants with different modifications on their central glycosyl ester linkage are described. Also described are methods of making and method of using such triterpene saponin variants.  
WO/2017/085144A1
The invention relates to new compounds of formulae: Wherein: R 1 and R 2 can be independently H; a C 1 to C 6 alkyl including methyl, ethyl, propyl, butyl; aryl including phenyl, para-methoxyphenyl; or R 1, R 2 together with the carbon C...  
WO/2017/079582A1
The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and ...  
WO/2017/013966A1
A germination inhibitor for thermophilic spore-forming bacteria, which comprises a sucrose fatty acid ester, wherein palmitic acid makes up 90 mol% or more of constituent fatty acids in the sucrose fatty acid ester. The present invention...  
WO2017010596A1
The present invention relates to: a protein having transglucosylation activity specific to carbon 3 of ascorbic acid; a composition for producing a vitamin C derivative; a compound represented by chemical formula 1 and produced by the pr...  
WO/2017/002120A1
Compounds useful for selectively eliminating senescent cells, compositions comprising same and uses thereof in treating diseases and disorders in which selective elimination of senescent cells is beneficial are provided. The compounds ar...  
WO/2016/194887A1
[Problem] To provide a method for producing a sucrose fatty acid ester having high monoester selectivity. [Solution] The method for producing a sucrose fatty acid ester according to the present invention is provided with a step for prepa...  
WO/2016/167255A1
Provided is a dextrin fatty acid ester, wherein the average sugar polymerization degree of the dextrin is 3-100. The fatty acid comprises one or more C14-18 straight-chain saturated fatty acids, and one or more C14-18 branched saturated ...  
WO/2016/139127A1
A method of extracting at least one rhamnolipid compound from a rhamnolipid fermentation mixture, the method comprising the steps of: (a) admixing an inert adsorbing support with a rhamnolipid fermentation mixture; (b) dissolving the mix...  
WO/2016/127543A1
Provided are a class of sucrose ester-type cationic lipoids and a preparation method therefor. A vector prepared by using the cationic lipoid can be used to deliver a nucleic acid. The sucrose ester-type cationic lipoid is prepared by us...  
WO/2016/120403A1
The present invention relates to a compound of the general formula (1). wherein the pyranose ring is a-D-galactopyranose, A is selected from The compound of formula (1) is suitable for use in a method for treating a disorder relating to ...  
WO/2016/109880A1
The invention provides lipid A mimics in which one or both of the sugar residues of a natural lipid A disaccharide backbone has been replaced with an aromatic group. These lipid A mimics may further differ from a natural lipid A molecule...  
WO/2016/092413A1
The present invention relates to indole and indazole compounds of Formula (I) Formula (I) that activate 5' adenosine monophosphate-activated protein kinase (AMPK). The invention also encompasses pharmaceutical compositions containing the...  
WO/2016/078947A1
The invention relates to concentrated rhamnolipid compositions and to methods for the synthesis thereof.  
WO/2016/070849A1
Provided in the present invention are a class of Lincomycin biosynthetic intermediates and a preparation method and use thereof. Specifically provided are Lincomycin biosynthetic intermediates obtained from the genetic modification of a ...  
WO/2016/047428A1
[Problem] To provide a cyclic hemiacetal compound production method that is performed under mild conditions easily and at a high yield and that is superior in stereoselectivity and enables mass production. [Solution] Provided is a produc...  
WO/2016/034894A3
The invention provides a combination of an antibacterial agent (in particular vancomycin or moenomycin) and a delivery agent, in which the delivery agent is bonded, or capable of binding, to the antibacterial agent, and in which the deli...  
WO/2016/026641A1
The invention relates to fatty acid polyester derivatives of polyglycosides and formed from a polyol comprising between 2 and 10 hydroxy functions, the 2 hydroxy functions or at least 2 of said hydroxy functions being attached to the ano...  
WO/2016/025790A1
Disclosed are UAP inhibitors to inhibit glucose flux in the hexosamine biohynthetic pathway and methods of treating a disease using the inhibitors.  
WO/2016/020635A1
There is provided a method for the chlorination of a sucrose-6-acylate to produce a 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose-6-acylate, wherein said method comprises the following steps (i) to (v): (i) providing a first compone...  
WO/2016/017677A1
The present invention can provide: a crystal of an alkali metal N-acetylneuraminate anhydrate; and a method for producing a crystal of an alkali metal N-acetylneuraminate anhydrate, said method being characterized by comprising: adding o...  
WO/2016/013938A1
The present invention relates to a family of carbohydrate monosulphate fatty acid esters, which contain less than 10 mole % of carbohydrate polysulphate fatty acid esters, and to a method of preparation thereof. The monosulphate carbohyd...  
WO/2016/005311A1
The present invention relates to a compound of the general formula (1). The compound of formula (1) is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal...  
WO/2016/005340A1
The present invention relates to hamamelitannin analogues, pharmaceutical compositions comprising the same, and combinations thereof with anti-microbial agents such as antibiotics or disinfectants. It in particular relates to the use of ...  
WO/2015/190489A1
 The purpose of the present invention is to provide a useful prodrug compound of a naphthofuran compound. The present invention pertains to a compound represented by general formula (IA): (the symbols in the formula are as stated in th...  
WO/2015/184451A1
Truncated triterpene saponin analogues containing a trisaccharide or tetrasaccharide ester are disclosed. Also disclosed are pharmaceutical compositions comprising truncated saponin analogues and synthetic methods of producing the trunca...  
WO/2015/177668A1
Compounds of Formula (A) are described herein and the uses thereof for the treatment of diseases, conditions and/or disorders mediated by pharmaceutical compositions and the uses thereof as asialoglycoprotein receptor (ASGPR) targeting a...  
WO/2015/158575A1
Calixarene compound according to formula (I) wherein: R1 represents a linear or branched C(1-16) alkyl group; R2 represents an hydrogen atom or a methyl group; R3 is identical to R1 or R2 group; R4 represents a saccharide residue, in whi...  
WO/2015/155536A1
A process for the production of a complex of lactic acid and either ammonia or an amine, comprising: a) reacting a stream rich in saccharide with sodium hydroxide to produce a reaction mixture comprising sodium lactate; b) contacting at ...  
WO/2015/143185A1
Provided herein is the design and synthesis of novel molecular rotor fluorophores useful for detection of amyloid or amyloid like proteins. The fluorophores are designed to exhibit enhanced fluorescence emission upon associating with amy...  
WO/2015/139128A1
A composition of purified and biologically active p-coumaroyl hexose and/or polyphenols is provided by separation from strawberry's pulp by a method of extraction and purification using a hydrophobic adsorbent using GRAS solvent. Also pr...  
WO/2015/125781A1
 A method for producing a compound represented by general formula (II) via a step for reacting a compound represented by general formula (I) with a sulfur compound, and a compound. In general formulas (I) and (II), R1 represents a hydr...  
WO/2015/123734A1
Abstract The invention relates to polymeric high viscosity liquid carrier materials (HVLCMs), in particular esterified polysaccharides, compositions comprising these HVLCMs, coatings for implants which are based on these HVLCMs, methods ...  
WO/2015/125782A1
 A method for producing a compound represented by general formula (II) via a step for reacting a compound represented by general formula (I) with a sulfur compound, and a compound. In general formulas (I) and (II), R1 represents a hydr...  
WO/2015/123756A1
This invention provides compound having a structure of Formulas: Furthermore, methods and uses of such compounds for covalently bonding to a sugar acceptor, to form modified protein therapeutics having reduced enzymatic hydrolysis, impro...  
WO/2015/122428A1
[Problem] To provide a method for producing an organic compound whereby a reaction between substances can be promoted. [Solution] A method for producing an organic compound comprising: a mixing step for mixing a first liquid with a secon...  
WO/2015/118498A1
The present invention relates to a stabilized kit for the preparation of a radiopharmaceutical. In particular, the present invention relates to the use of a non-aqueous solvent for the stabilisation of the ligand component of the kit.  
WO/2015/111627A1
 The purpose of the present invention is to provide an amino acid precursor capable of improving the properties (especially water solubility, stability in water, bitterness, and the like) of an amino acid and being converted into an am...  

Matches 1 - 50 out of 3,579