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WO/2018/142288A1 |
The invention relates to compounds and pharmaceutical compositions for use in treating malaria infections. The invention also relates to uses and methods of treating a malaria infection in a subject using the compounds and pharmaceutical...
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WO/2018/139436A1 |
The present invention provides: a heterocyclic compound which exhibits an excellent controlling effect against harmful arthropods and which is represented by formula (I) (in the formula, Q denotes a group represented by Q1 or the like, A...
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WO/2018/140533A1 |
Compositions are provided that contain sporulated coccidial oocysts, wherein the compositions are free of antibiotics and comprise formalin at a concentration sufficient to inhibit microbial growth for at least 12 months while maintainin...
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WO/2018/132882A1 |
The present invention pertains to the field of the production of recombinant proteins, using a synthetic gene for increased expression of the protein in Pichia pastoris. More specifically, the invention describes the production of the re...
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WO/2018/129618A1 |
The present disclosure relates to compounds of Formula (I) which are multimeric forms of a monomeric binding peptide linearly bonded to PEG moieties to form the multimers. The multimeric forms stimulate angiogenesis and promote wound hea...
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WO/2018/130853A1 |
The present invention relates to novel compounds and pharmaceutically acceptable salts or solvates thereof which have activity as inhibitors of Schistosoma growth. The invention also relates to pharmaceutical compositions comprising such...
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WO/2018/124129A1 |
The present invention addresses the problem of developing and providing a novel agricultural and horticultural insecticide due to factors such as the development of pests resistant to existing chemicals since damage by pests is still a m...
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WO/2018/124088A1 |
Provided are novel pest control agents, in particular, a bactericide and a nematicide. An alkylphenyl-substituted amide compound represented by formula (I) [wherein: G1 stands for a structure represented by G1-2, G1-3, G1-4, etc.; X1 sta...
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WO/2018/124181A1 |
The present invention provides a functionalized mRNA including mRNA and double-stranded RNA including at least one RNA oligomer hybridized with mRNA. Functionalized mRNA is provided according to this configuration.
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WO/2018/124896A1 |
The subject of the invention is a composition for prevention and control of bee diseases and the use of the hemp oil for preparation of the composition. In more detail, the invention relates to a composition comprising hemp essential oil...
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WO/2018/115532A1 |
The invention relates to a composition comprising at least one compound of formula I R-SOa-S-R' (I), in which a is equal to 1 or 2 and R and R' are, independently of one another, a linear or branched C1-C5 alkyl group, for use in the pre...
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WO/2018/118979A1 |
The present disclosure relates to the use of hepcidin in therapeutic methods for the treatment of various conditions in which decreasing serum iron concentration may be beneficial.
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WO/2018/116945A1 |
A compound represented by formula (I) or a salt thereof; and a pest control agent which contains, as an active ingredient, at least one substance selected from the group consisting of compounds represented by formula (I) and salts thereo...
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WO/2018/107284A1 |
Sprayable compositions comprising a pyrethroid, a viscosity building agent, an emulsifier or surfactant, and an emollient are provided. The compositions have a viscosity that allows for delivery of the spray from a pressurized container ...
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WO/2018/106966A1 |
Methods and compositions for preventing and/or treating diseases and conditions caused by certain apicomplexan infections are provided. The methods involve administering/providing to a subject one or more of tartrolon D and E, including ...
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WO/2018/105632A1 |
The present invention addresses the problem of developing and providing a novel insecticide for agricultural and horticultural use since pests still cause extensive damage on the production of agricultural and horticultural crops and pes...
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WO/2010/056999A9 |
The present invention relates to novel aryloazol-2-yl-cyanoethylamino derivatives substantially enriched in an enantiomer of formula (I): wherein R3, R4, R5, R6, R7, R13a, R13b, R14a, R14b, P, Q, V, W, X, Y, Z and a are as defined in the...
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WO/2018/100178A1 |
The invention provides a method for the production of a zeolite particle composition which has optimized characteristics, such as enhanced adsorption and specific ion exchange properties. A method and an apparatus for producing improved ...
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WO/2018/100292A1 |
The invention relates to the use of a bacterial mixture for the prevention and improvement of the state of ungulates suffering from pathologies involving a parasitic or bacterial infection of the foot, said composition comprising: at lea...
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WO/2018/096087A1 |
The present invention relates to a veterinary composition comprising diminazene and levamisole or salts thereof, wherein the weight ratio of diminazene or its salts to levamisole or its salts ranges from 0.50 to 2.00. The present inventi...
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WO/2018/094100A1 |
Disclosed herein are compositions comprising complexes of cyclodextrins and lipid- modified stem cell proteins. Also disclosed are topical compositions the complexes. Methods of using the compositions for the therapeutic purposes are als...
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WO/2018/090100A1 |
The present disclosure relates to methods and products for reducing resistance to anti-parasitic agents. In certain embodiments, the present disclosure provides a method of reducing resistance to an anti-parasitic agent in an animal suff...
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WO/2018/088509A1 |
The present invention provides a polypeptide and a malaria vaccine comprising said polypeptide, the polypeptide comprising any of the following amino acid sequences: (a) an amino acid sequence represented by SEQ ID NO. 4; (b) an amino ac...
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WO/2018/087036A1 |
The present invention covers new quinoline compounds of general formula (I) in which A, R1, R2, R3, R4, R5, R6, and Q are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds,...
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WO/2018/089661A1 |
Presented herein, in certain embodiments, are compositions comprising synthetic polypeptides that specifically bind to MHC Class I.
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WO/2018/088507A1 |
The present invention provides a polypeptide and a malaria vaccine comprising said polypeptide, the polypeptide comprising any of the following amino acid sequences: (a) an amino acid sequence represented by SEQ ID NO. 4 or SEQ ID NO. 8;...
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WO/2018/084142A1 |
The production of agricultural and horticultural crops, etc. is still seriously damaged by insect pests and the like and there are causative factors such as the appearance of insect pests resistant to the conventional chemicals. Under th...
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WO/2018/084141A1 |
The production of agricultural and horticultural crops, etc. is still seriously damaged by insect pests and the like and there are causative factors such as the appearance of insect pests resistant to the conventional chemicals. Under th...
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WO/2018/079629A1 |
The present invention provides a novel 2,4,6-substituted pyrimidine derivative, which is a compound represented by formula (I) (in the formula, ring A is a 6-membered heteroaryl group having at least one N atom optionally substituted wit...
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WO/2018/073474A1 |
The present invention relates to a new series of compounds derived from 2,4-dihydroxybenzoic acid. The invention also relates to a pharmaceutical composition that comprises said compounds and to the use thereof in the treatment or preven...
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WO/2018/068114A1 |
The present invention relates to a combination of the drugs curcumin (Cur), which is a natural polyphenol, and sodium diethyldithiocarbamate (DETC), or its precursor disulfiram (DS), which exhibits synergistically increased antimalarial ...
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WO/2018/068090A1 |
The present invention relates generally to the field of glycanics and its application to the generation of glycoconjugates for therapeutic use. The present invention also relates to process for the preparation of glycoconjugates.
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WO/2018/069420A1 |
The present invention is related to new trioxolane derivatives in the manufacture of a medicament for preventing or treating malaria. Specifically, the present invention is related to trioxolane derivatives useful for the preparation of ...
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WO/2018/071741A1 |
The invention provides sulfoxyalkyl organonitro and related compounds, compositions containing such compounds, and methods for using such compounds and compositions to treat medical disorders, such as a neurodegenerative disorder, autoim...
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WO/2018/071836A1 |
Disclosed are compounds of formula (I) and formula (II): (I) (II) wherein R1, R2, A, and B are as defined herein. Also disclosed is a method of blocking transmission of a Plasmodium parasite and a method of treating or preventing malaria...
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WO/2018/070502A1 |
There has been a demand for the development of a novel pesticide for agricultural and horticultural use for reasons such that pests still cause extensive damage on the production of agricultural and horticultural crops and the like and p...
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WO/2018/070503A1 |
In crop production such as agriculture and horticulture, damage by pests and the like is still significant, and development of a novel agricultural and horticultural insecticide is desired due to factors such as the appearance of pests t...
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WO/2018/065809A1 |
The present invention relates to pharmaceutical compositions that can be used for the treatment of trichomoniasis, which comprise compounds with the chemical structure and which also exhibit a synergic effect and do not have the typical ...
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WO/2018/060423A1 |
The invention relates to novel compounds which are naphthalene diimide sugar conjugates of general formula (I) and its procedure of obtainment. The compounds of the invention are used in therapy; particularly they have shown antiprolifer...
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WO/2018/061006A1 |
The invention relates to cell preparations comprising dendritic cell (DC) sub- populations, methods of obtaining such cell preparations, and the use of such preparations for improved immune and cancer therapy. More specifically, embodime...
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WO/2018/062246A1 |
Provided is a method for controlling microsporidia or myxosporea in marine fishes (particularly cultured fishes) with an oral administration agent. A control agent for "Beko" disease or a myxosporean disease mediated by microsporidia par...
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WO/2018/062082A1 |
The purpose of the present invention is to provide a mesoionic compound, which exhibits an improved controlling effect on various harmful organisms, or a salt thereof. A mesoionic compound represented by formula (1) (wherein: R1 is selec...
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WO/2018/060483A1 |
The invention relates to compounds characterized by a general formula (1), wherein OM is an organometallic compound. OM is independently selected from the group of an unsubstituted or substituted metal sandwich compound, an unsubstituted...
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WO/2018/063472A1 |
This disclosure is directed to pharmaceutical, compositions for treating a parasitic disease, comprising Praziquantel or its analogues aid an extract isolated from Schisandra chinensis. The parasitic disease is susceptible to treatment w...
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WO/2018/050815A1 |
The present invention relates to a compound of formula (I), in which R' represents a -(CRaRb)n-X-(CRcRd)m-[Y-(CReRf)o]t-NR9R10 group, and X and Y independently represent a -NR11- group, an –O- group or a divalent heterocyclic group com...
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WO/2018/050814A1 |
The present invention relates to a compound of formula (I), in which R' represents a –(CRaRb)n-X-(CRcRd)m-[Y-(CReRf)o]t-NR9R10 group, and X and Y independently represent a -NR11- group, an –O- group or a divalent heterocyclic group c...
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WO/2018/049459A1 |
Apicomplexan parasites or red blood cells infected with apicomplexan parasites are administered to an animal in combination with a delayed death agent that initially allows parasite replication but subsequently kills the apicomplexan par...
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WO/2018/051291A1 |
The present technology relates to vaccine compositions comprising at least one of the nine peptides defined by SEQ ID NO 1-9, capable of stimulating the development of a T helper 1 (Th1)-type cell immune response with high production of ...
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WO/2018/049124A1 |
This disclosure is directed to immune treatment of a disease (e.g., an infectious disease) using a fusion protein in combination with an anti-chemorepellant agent. In particular, the fusion protein comprises an antigen-binding domain (e....
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WO/2018/046584A1 |
The invention is related to a cheap, efficient and low-environmental impact method for the preparation of highly pure 4-bromothymol, that can be obtained by the catalytic oxidative bromination of thymol. The oil obtained as product from ...
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