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WO/2021/045207A1 |
The present invention relates to a production method for a highly reactive intermediate. The production method includes: preparing an electron-accepting active compound (1); preparing a piezoelectric material (3); and applying mechanical...
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WO/2021/018572A1 |
The present invention relates to air stable, binary Ni(0)-olefin complexes and their use in organic synthesis.
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WO/2021/000248A1 |
Disclosed in the present invention are a method and an apparatus for continuous synthesis of cyclopropane compounds. The method comprises the following steps: the synthesis reaction of a diazomethane precursor is carried out continuously...
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WO/2020/230555A1 |
A method for forming a carbon-carbon bond, wherein: a reaction is performed by filling a container with a platinum group metal-loaded catalyst and having a starting material liquid permeate through the platinum group metal-loaded catalys...
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WO/2020/185105A1 |
An improved method for the synthesis of pyrrolo[3,2-b] pyrroles using iron (III) salts as a catalyst is disclosed.
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WO/2020/156022A1 |
Provided herein are enantioselective organocatalytic methods for preparing chiral tetraaryl methanes.
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WO/2020/081723A1 |
The present invention provides new compounds and compositions thereof that release carbon monoxide for the treatment of medical disorders that are responsive to carbon monoxide, for example, inflammatory, pain, and dermatological disorders.
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WO/2019/229239A1 |
A compound of formula (I) wherein: M is selected from Mo or W; X is selected from O or NR5; R1 and R2 are independently selected from H, C1-6 alkyl, and aryl; C1-6 alkyl and aryl optionally being substituted with one or more of C1-6 alky...
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WO/2019/225742A1 |
Constructed is a technology capable of coupling organic compounds efficiently, inexpensively, simply, and in a short time by a small number of steps. A method for coupling organic compounds, wherein the method for coupling organic compou...
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WO/2019/159596A1 |
Provided is a method for preparing a coupled body represented by general formula (3), the coupled body being obtained by reacting a compound represented by general formula (1) and a compound represented by general formula (2) in the pres...
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WO/2019/096832A1 |
Photocatalyst system and use thereof in a photochemical process The invention relates to a photocatalyst system comprising, in the absence of a further photosensitizer other than the compound of formula (III) or a mixture thereof: (i) a ...
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WO/2019/096762A1 |
The invention relates to methods for forming CC bonds with use of organolithium compounds under continuous flow conditions in a micro or meso reactor system, in which an organic substrate is reacted with an alkyl lithium compound in the ...
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WO/2019/060998A1 |
The present disclosure relates to reagents and method for performing trifluoromethylation, difluoromethylation or alkylation of aromatic or heteroaromatic rings in a redox-neutral manner without any catalyst which are enabled by light. I...
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WO/2019/020726A1 |
The invention discloses a method for preparation of alkylated, fluoro alkylated, chloro alkylated and fluorochloro alkylated compounds by a heterogeneous Co-catalysed alkylation or fluoro, chloro and fluorochloro alkylation with alkyl ha...
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WO/2018/214044A1 |
The present invention is a process for preparing skipped dienes from simple endocyclic dienes and simple olefins by a transition metal catalyst.
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WO/2018/187717A1 |
This disclosure generally relates to methods of making ibuprofen, naproxen, and derivatives thereof. This disclosure also generally relates to compounds made by the disclosed methods. This abstract is intended as a scanning tool for purp...
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WO/2018/178374A1 |
The invention relates to a method for the production of a material of plant origin that is rich in phenolic acids, comprising at least one metal, said method comprising the following steps: a) producing a material of plant origin selecte...
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WO/2018/173058A1 |
The present invention provides processes for the preparation of diverse heterocyclic scaffolds from alpha-enaminone building bloc of formula (I).
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WO/2018/158140A1 |
The present invention relates to a method for the synthesis of a halo olefin of formula (I) wherein Hal, R1, R2, R3, R4, X and Y are defined according to claim 1, or a salt thereof comprising the step of protodecarboxylation of an a-halo...
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WO/2018/156500A1 |
Methods of synthesizing polyfluorinated amino acid derivatives are disclosed, along with polyfluorinated amino acid derivatives produced from said methods, as well as compositions containing same. The synthesis methods utilize an oxazolo...
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WO/2018/115029A1 |
Disclosed are novel metal organic compounds, a method for their production and their use to make catalytically active compounds, which can be used in well-established methods of organic synthesis.
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WO/2018/106336A1 |
The invention is certain mono-ligated palladium catalysts that are easy to synthesize and are effective in Suzuki coupling reactions. The mono-ligated catalysts comprise a ring structure having a substituent group with a nitrogen atom ad...
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WO/2018/106338A1 |
The present invention is mono-ligated palladium catalysts that are easy to synthesize and are effective in Suzuki coupling reactions. Specifically these catalysts are characterized by an aromatic ring having a substituent with two nitrog...
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WO/2018/093924A1 |
Carbon monoxide-releasing organic molecules are described herein. The molecules can be synthesized prior to administration (e.g., ex vivo) or formed in vivo. In those embodiments where the molecules are formed in vivo, reactants are admi...
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WO/2018/087230A1 |
Compound of formula (4) or formula (5), wherein L is a neutral ligand, preferably a nitrogen-containing heterocyclic carbene (NHC) such as carbene containing at least two nitrogen atoms, a cyclic aminoalkyl carbene (CAAC) or a bicyclic a...
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WO/2018/080897A1 |
Pd(II)-catalyzed g-G(sp3)-H arylation or heteroarylation of primary amines is realized by using 2-hydroxynicotinaldenyde as a catalytic transient directing group. Importantly, the catalyst and the directing group loading can be lowered t...
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WO/2018/038742A1 |
Compositions comprising bridged bicyclic-based compounds such as iptycene-based compounds and methods for mechanochemically synthesizing them are generally provided. In some cases, two or more polycyclic aromatic hydrocarbons may be mech...
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WO/2018/019630A1 |
The present invention relates to a catalyst system comprising a transition metal compound on a solid carrier which is a "surface-reacted calcium carbonate" comprising calcium carbonate and a water-insoluble calcium salt other than calciu...
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WO/2018/019291A1 |
Provided is a method of synthesizing a C(sp3)-C(sp2) cross-coupled compound comprising reacting a C(sp3) coupling partner with a C(sp2) coupling partner, a catalyst, and a solvent; wherein the C(sp3) coupling partner comprises an organic...
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WO/2017/194100A1 |
The invention relates to a method for producing cationic silicon (II) compounds of general formula (RaSi) +HA- (I) by reacting the silicon (II) compounds of general formula II (Rb-H) (RaSi)+ (II) with a hydride acceptor compound A, where...
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WO/2017/173975A1 |
Disclosed in the present application is a process for the preparation of a compound III containing a non-terminal carbon-carbon double bond, characterized in that, a compound I containing a carbon-carbon double bond, in the presence of a...
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WO/2017/173128A1 |
Polyarylenes are attractive polymers that can exhibit improved mechanical and optical and improved chemical and thermal stability as compared to non-polyarylene organic polymers. Copolymerization of tetrazine monomers with diethynylarene...
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WO/2017/168303A1 |
The present invention is directed to reaction mixtures comprising a water-surfactant mixture and a co-solvent. This technology reduced the amount of organic solvents needed for performing chemical reactions. Furthermore, compared to reac...
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WO/2017/154948A1 |
The present invention addresses the problem of providing a novel method for producing a compound having a fluoromethylene group with high efficiency. The problem can be solved by a method for producing a compound represented by formula (...
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WO/2017/106426A4 |
The present application discloses a nanoparticle composition prepared from a mixture comprising: a) a transition metal salt; b) an iron salt; and c) a reducing agent; and methods for the use of such compositions, including the reduction ...
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WO/2017/129796A1 |
The present invention relates to a method of carrying out an organic reaction in aqueous solution in the presence of a hydroxyalkyl(alkyl)cellulose or an alkylcellulose.
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WO/2017/112576A1 |
The present disclosure describes a method of coupling a first aromatic compound to a second aromatic compound, the method comprising: (a) preparing a reaction mixture comprising the first aromatic compound, the second aromatic compound, ...
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WO/2017/104589A1 |
Provided is a method for producing a perfluoroalkylated compound at low cost, safely and with high efficiency. A method for producing a perfluoroalkylated compound, comprising reacting a bis(perfluoroalkanoyl)peroxide with a compound tha...
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WO/2017/106426A1 |
The present application discloses a nanoparticle composition prepared from a mixture comprising: a) a transition metal salt; b) an iron salt; and c) a reducing agent; and methods for the use of such compositions, including the reduction ...
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WO/2017/083719A1 |
The present disclosure provides methods of preparing biaryl compounds which do not require transition metal catalysts. In yet another aspect, the present disclosure provides pharmaceutical compositions comprising compounds as described h...
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WO/2017/063558A1 |
Provided is a composite material in catalytic hydrogenolysis. The composite material comprises: stacked graphene having a boundary surface; and multiple metal nanoparticles distributed in a certain proportion and attached to the boundary...
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WO/2017/050419A1 |
The invention relates to bismuth perfluoroalkylphosphinates as Lewis acid catalysts, the compounds and a method for the production thereof. ArxBi[OP(O)(Rf)2]3 -x (la), Ar3Bi[OP(O)(Rf)2]2 (Ib).
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WO/2017/019487A1 |
Provided herein are methods and intermediates for making (lR,2R,5R)-5-amino-2- methylcyclohexanol hydrochloride, which are useful for the preparation of compounds useful for the treatment of a disease, disorder, or condition associated w...
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WO/2017/008832A1 |
Polymer supported fluorinated compound of formula I, wherein the meaning for each R1 is as disclosed in the description. These compounds are useful as catalysts, particularly in Michael addition reactions under continuous flow.
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WO/2016/198836A1 |
Processes of forming Csp2-Csp3 bonds at the allylic carbon of a cyclic allylic compound starting material are disclosed, in which a racemic mixture of a cyclic allylic compound having a leaving group attached to the allylic carbon is rea...
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WO/2016/176729A1 |
The present invention relates to novel bacteriocins with a wide antimicrobial activity against bacteria, including food spoilage and pathogenic bacteria, and the genes that encode said bacteriocins. In particular, the present invention r...
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WO/2016/172609A1 |
Provided are methods for the production of isophthalic acid (IPA) and derivatives thereof. The methods are based on the addition of beta propiolactone to furfural or a derivative thereof. Provided are cost effective routes to biobased IP...
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WO/2016/146689A1 |
Provided is an organozinc composition comprising (a) an organozinc complex carrying an allylic ligand, (b) a magnesium component and (c) a lithium component. The organozinc composition is useful as a synthetic intermediate with excellent...
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WO/2016/141836A1 |
The invention relates to a method for synthesizing a phenanthrene compound, as shown by formula (I) below, using copper acetylacetonate. The method comprises the following steps: reacting a compound as shown by formula (II) below and a c...
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WO/2016/141825A1 |
The present invention relates to a method for synthesizing medical intermediate phenanthrene compounds, as shown as shown by formula (I) below, in a sodium acetate environment. The method comprises the following steps: reacting a compoun...
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