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Matches 1 - 50 out of 10,499

Document Document Title
WO/2021/065382A1
Provided is a fluorine-containing ether compound represented by formula (1). The fluorine-containing ether compound is characteristically represented by formula (1) below. (1): R1-R2-CH2-R3-CH2-R4 (R3 is a perfluoropolyether chain; R1 is...  
WO/2021/058024A1
Provided are a class of heterospirocyclic compound which act as a lysine-specific demethylase 1 (LSD1) inhibitor, and a use thereof in the preparation of a drug for treating diseases associated with LSD1. The heterospirocyclic compounds ...  
WO/2021/059999A1
Provided is a liquid crystal aligning agent from which a liquid crystal alignment film, which is highly able to align liquid crystals, is obtained even when exposed to excessive heating. The liquid crystal aligning agent has a group re...  
WO/2021/054202A1
A fluorine-containing ether compound represented by formula (1). (1): R1-R2-CH2-R3-CH2-R4 (In the formula, R1 represents an organic group having an alicyclic structure and from 3 to 13 carbon atoms; R2 represents a group expressed by for...  
WO/2021/052271A1
A magnolol derivative and a preparation method therefor and an application thereof. The magnolol derivative has a structure represented by formula (1). The magnolol derivative has good water solubility, is colorless and transparent after...  
WO/2021/052270A1
The present invention relates to the field of honokiol derivatives. Disclosed are a honokiol derivative, a preparation method therefor and the use thereof, wherein the derivative has a structure as shown in formula (I). The honokiol deri...  
WO/2021/050648A1
The invention features methods of treating cancer with 2-[3-[(3R)-3-[[2-chloro-3- (trifluoromethyl)phenyl]methyl-(2,2-diphenylethyl)amino]buto xy]phenyl]acetic acid. The disclosure also provides methods of treating cancer including combi...  
WO/2021/036158A1
The present invention relates to the technical field of organic small molecule hole injection/transport materials. Disclosed are an organic small molecule hole injection/transport material and a preparation method therefor and an applica...  
WO/2021/039843A1
The present invention addresses the problem of providing: a (poly)amine compound which is particularly useful as a material for forming a film for lithography or as a material for forming an optical component; a resin which is obtained u...  
WO/2021/037750A1
Novel compounds are disclosed. Skin lightening composition comprising said compounds and method of skin lightening is disclosed too. In addition, method of synthesizing said novel compounds are disclosed.  
WO/2021/026647A1
Disclosed herein is a lipid having a net charge at physiological pH, and being covalently attached to a lipid moiety. The lipid moiety comprises a hydrocarbon structure having two or more linked hydrocarbon chains, optionally having cis ...  
WO/2021/028506A1
The invention relates to processes for preparing 2 -methoxymethyl-p-phenylenediamine (I), cosmetically acceptable salts thereof, or mixtures thereof.  
WO/2021/019998A1
Provided is a compound capable of realizing a lubricant having excellent adhesion to a magnetic disc, especially to a protective layer. A perfluoropolyether compound according to an embodiment of the present invention has a structure in ...  
WO/2021/012689A1
Disclosed herein are phenylthiophene sulfonamide compounds, pharmaceutical compositions, a preparation method therefor and use thereof. The compounds of the present invention are capable of effectively and selectively inhibiting Bcl-xL, ...  
WO/2021/003433A1
The present disclosure provides sustained release compositions of (Z)-endoxifen and polymorphs and salts thereof and methods of making sustained release compositions of (Z)-endoxifen and polymorphs and salts thereof. The present disclosu...  
WO/2020/257940A1
The present application provides furosemide analogues of the general formula Z having activity as anti-Aβ aggregation agents and/or as inhibitors of Aβ induced neuroinflammation. Formula Z These compounds are useful in preventing, dela...  
WO/2020/256863A1
The present disclosure provides water-based well treatment fluids methods of using such fluids in treating subterranean formations to prevent swelling and/or migration of fines. The water-based well treatment fluid contains an aqueous co...  
WO/2020/214399A9
A method of carrying out a metathesis reaction includes the combination of at least one alkene or non conjugated diene with a Ruthenium-based catalyst with an cyclic(alkyl)(amino)carbene ligand to form a reaction mixture, heating the rea...  
WO/2020/244323A1
Disclosed are a preparation method for a cis-p-mentha-1,8-secondary amine compound and a herbicidal application thereof. The method comprises: using a cis-p-mentha-1,8-di-schiff base compound as a raw material, putting reducing agents in...  
WO/2020/237806A1
The present invention relates to the field of organic synthesis. Provided is a preparation method for 4-fluorine-3-methoxyl-5-methylaniline hydrochloride. A synthetic route of the preparation method for 4-fluorine-3-methoxyl-5-methylanil...  
WO/2020/241123A1
Provided is a production method that is for a water absorbent which can simultaneously provide satisfactory absorption against pressure (AAP) and gel bed permeability (GBP) without essentially requiring the use of an epoxy crosslinking a...  
WO/2020/214399A3
A method of carrying out a metathesis reaction includes the combination of at least one alkene or non conjugated diene with a Ruthenium-based catalyst with an cyclic(alkyl)(amino)carbene ligand to form a reaction mixture, heating the rea...  
WO/2020/229014A1
The invention concerns a compound of Formula (I) or a salt thereof, wherein R1 is H, (C1-C3)alkyl or CF3; R2 is H, (C1-C3)alkyl or CF3; A is CH2COOH, XCH2COOCH2CH3, XCH2COOH, XCH2CH2NH2, where X is nitrogen or oxygen atom; Ar is an aroma...  
WO/2020/220942A1
A compound, an organic electroluminescent device containing the compound, and an application thereof. The compound has a structure shown in (I).  
WO/2020/223225A1
Described are compounds, compositions, and methods that include oxygenated aromatic amines, such as an aminophenol-, phenyl-p- phenylenediamine-, and diaminobenzene-based compound useful as antioxidants. The oxygenated aromatic amine inc...  
WO/2020/212510A1
The present invention is directed to methods for the asymmetric synthesis of esketamine. The present invention is further directed to key intermediates in the asymmetric esketamine synthesis. In one embodiment, the invention is an asymme...  
WO/2020/214692A1
Tertiary amine and quaternary ammonium compounds of Formula I and/or Formula II are provided. The present technology also provides compositions that include one or more of the compounds that may be useful for electronics processing (e.g....  
WO/2020/210823A1
The invention features compounds and pharmaceutical compositions having anti-inflammatory properties. Also provided are methods of using the compounds or compositions of the invention for treating an inflammatory disorder in a subject in...  
WO/2020/208139A1
The present invention relates to new inhibitors of Notch signalling pathway and its use in the treatment and/or prevention of cancers.  
WO/2020/202940A1
Provided is a catalytic mixture with sufficient catalytic efficiency, wherein pressure loss is small when the catalytic mixture fills a flow reactor and a reactive solution is caused to flow therethrough, and the catalytic efficiency and...  
WO/2020/203580A1
The present invention provides a method for producing a hetero type monodisperse polyethylene glycol having a step (A) for subjecting a compound of formula (2) and a compound of formula (3) to a nucleophilic substitution reaction so as t...  
WO/2020/084599A4
The present invention relates to ammonium salts of partially fluorinated organic acids, represented by the general formula 1. The present invention relates also to a synthesis method of said salts as well as its use to the production of ...  
WO/2020/203444A1
A compound which has, between end groups arranged at both ends and each having a reactive group, a first structure wherein an aromatic ring group, an ether oxygen atom, a methylene group, an aromatic ring group, a methylene group, an eth...  
WO/2020/194326A1
The present invention relates to a process for the preparation of tapentadol and analogs or compounds or stereoisomers of formula (I), Formula I wherein, A is aryl, heteroaryl, and cycloalkyl; R is H, OH, OR1, halogen, C1-C12 alkyl, cycl...  
WO/2020/185872A1
Formamide group-containing monomers and polymers made by polymerizing the monomers are provided. Also provided are methods of polymerizing the monomers and methods of synthesizing functionalized polymers by pre- and/or post-polymerizatio...  
WO/2020/167855A1
Useful processes of preparation and intermediates useful for the preparation of Compound 1, a selective estrogen receptor alpha (ERα) modulator/degrader (SERM/SERD), having utility for the treatment of ER+ cancers including breast cance...  
WO/2020/156522A1
Provided are a dezocine derivative of formula I or a tautomer, optical isomer, oxynitride, solvate, pharmaceutically acceptable salt or prodrug thereof, and a pharmaceutical composition comprising the same, a preparation method therefor,...  
WO/2020/158925A1
A method for producing a nitroso compound of formula (3), which comprises a process for reacting a compound of formula (1) and a compound of formula (2) with each other by using a tertiary alcohol and a base. (In the formulae, each of R1...  
WO/2020/158523A1
The purpose of the present invention is to provide a diamine compound that can yield a resin that has both excellent solvent solubility (solution processability) and high heat resistance, a polyimide synthesized from said diamine compoun...  
WO/2020/084599A3
The present invention relates to ammonium salts of partially fluorinated organic acids, represented by the general formula 1. The present invention relates also to a synthesis method of said salts as well as its use to the production of ...  
WO/2020/104648A3
A compound of formula (I) with improved TGFβ signaling pathway inhibitory activity, improved therapeutic efficacy and improved toxicity profile, as well as two prodrugs thereof are disclosed. Compositions comprising said TGFβ signaling...  
WO/2020/138398A1
The present invention addresses the problem of providing a novel compound exhibiting a high LSD1-inhibiting activity, high selectivity for LSD1 inhibition, and/or having a useful therapeutic effect for various diseases. One embodiment pe...  
WO/2020/126819A1
The present invention relates to a process for preparing compounds of the formula (I), starting from compounds of the formula (II), wherein R1, R2, R3 and R3' are defined according to the invention.  
WO/2020/121667A1
An ammonium salt having a saccharin anion, which is represented by formula (1), exhibits excellent thermal stability even though no halogen atom is contained therein. (In the formula, each of R1-R4 independently represents an alkyl group...  
WO/2020/119147A1
Disclosed are a bicomponent epoxy mortar for pasting PVC and treating concrete expansion joints, a preparation method therefor and the use thereof. The raw materials of the epoxy mortar comprise a component A and a component B. The raw m...  
WO/2020/121326A1
The present invention provides an amorphous form of (rac)-tramadol.HCl-celecoxib (1:1) and a solid dispersion and processes for the preparation of the same.  
WO/2020/106933A1
The present disclosure relates to novel compounds having estrogen receptor alpha degradation activity, pharmaceutical compositions containing such compounds, and their use in prevention and treatment of cancer and related diseases and co...  
WO/2020/104648A2
A compound of formula (I) with improved TGFβ signaling pathway inhibitory activity, improved therapeutic efficacy and improved toxicity profile, as well as two prodrugs thereof are disclosed. Compositions comprising said TGFβ signaling...  
WO/2020/090989A1
In a production method for a fluorinated aromatic secondary or tertiary amine compound having a fluoroaryl moiety in a molecule, the method comprising reacting a fluorinated aromatic primary amine compound with a chlorinated, brominated,...  
WO/2020/084599A2
The present invention relates to ammonium salts of partially fluorinated organic acids, represented by the general formula 1. The present invention relates also to a synthesis method of said salts as well as its use to the production of ...  

Matches 1 - 50 out of 10,499