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WO/2024/088373A1 |
A titanium silicalite molecular sieve having a hierarchical-pore structure. Peaks of the 1H MAS NMR spectrum of the titanium silicalite molecular sieve in a chemical shift range of 1-6 ppm are subjected to peak fitting to obtain five pea...
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WO/2024/059287A3 |
An orally ingestible contraceptive composition for a pig or rodent is provided. The exemplary composition comprises 0.005 to 1.4 wt. % free gossypol and non-free-gossypol matter. The non-free-gossypol matter comprises a bulk feed compone...
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WO/2024/089225A1 |
The present invention provides, inter alia, a process for preparing a compound of formula (I) wherein the substituents are as defined in claim 1.
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WO/2024/071178A1 |
Provided is an industrially useful method for producing an alkylsilyloxy-substituted benzylamine compound, in which impurities are easily removed and the method does not involve an alkylsilyloxy-substituted benzyl compound that is an int...
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WO/2024/061348A1 |
The present invention provides a 1,3-cyclohexanedione compound shown in formula I, and a stereoisomer and an agrochemically acceptable salt thereof, wherein R1, R2, R3, and R4 are as defined in the description. Also disclosed are a prepa...
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WO/2024/047674A1 |
The present invention provides a novel manganese catalyst (Formula I) and their process of preparation thereof. The present invention also provides process of hydrogenation wherein the novel manganese catalyst used for hydrogenation of v...
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WO/2024/038436A1 |
The present invention relates to the preparation of cyantraniliprole, comprising the preparation of 8-methyl-2,4-dioxo-l,4-dihydro-2H-benzo[d][l,3]oxazine-6-car
bonitrile key intermediate via 2-amino-5-((hydroxyimino)methyl)-3-methylbenz...
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WO/2023/247909A1 |
The invention relates to a method for continuously preparing azine, which comprises a step of reacting ammonia, hydrogen peroxide and a ketone of formula R1R2CO, the groups R1 and R2 denoting, independently of each other, a methyl, ethyl...
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WO/2023/236809A1 |
The present invention belongs to the technical field of anti-inflammatory drugs. Disclosed are a 2,6-dibenzylidene cyclohexanone oxime compound, a method for preparing same, and use thereof. According to the present invention, a structur...
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WO/2023/124970A1 |
Disclosed are a cyclic 1,3-diketodiimine compound with a symmetrical structure, a synthesis method and use thereof. The compound has a structure represented by the following general formula (III), (II), or (III): wherein R1-R5 are each i...
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WO/2023/125001A1 |
A cyclic 1,3-diketonediimine compound, and a synthesis method therefor and the use thereof. The cyclic 1,3-diketonediimine compound has a structure as shown in the following general formulas I, II or III, wherein R1-R8 are each independe...
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WO/2023/101319A1 |
The present invention relates to a method for preparing an oxime derivative more easily by using a nitrogen oxide as a NO supply source under mild conditions.
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WO/2023/060811A1 |
Disclosed in the present invention are a fluralaner intermediate and a method for preparing fluralaner thereby. The fluralaner intermediate-5 is aaa. A synthetic route comprises: using m-xylene as a starting raw material, performing halo...
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WO/2023/279773A1 |
Provided are a preparation method for a tedizolid intermediate represented by formula (I), and an intermediate. The method comprises: 1) reacting 2-fluoro-4-substituted phenylacetic acid with a Vilsmeier reagent, and then adding a reacti...
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WO/2022/257957A1 |
The present invention relates to a use of γ,δ-unsaturated oxime ester compounds of formula (I) as photoinitiators, wherein variables are as defined in the description. The present invention further relates to a preparation method for t...
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WO/2022/249003A1 |
The present invention relates to an improved process for the preparation of intermediate of Trifloxystrobin in single isolation stage. The present invention provides an improved process for the preparation of (E)-2-(2-halomethylphenyl)-2...
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WO/2022/218391A1 |
The present invention relates to a chiral spiro ammonium salt compound, and a preparation method therefor and an application thereof. Specifically, the compound has the following optical pure or racemic compound represented by structural...
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WO/2022/207427A1 |
A compound of formula (I)(I).
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WO/2022/193368A1 |
The present invention belongs to the technical field of medicinal chemistry, and disclosed are a trans-amantadine derivative or a salt thereof, and a preparation method therefor, a composition thereof and the use thereof. Provided in the...
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WO/2022/193369A1 |
The present invention relates to the technical field of pharmaceutical chemistry. Disclosed is a use of a trans amantadine derivative having a structure as represented by formula I or a pharmaceutically acceptable salt thereof in the pre...
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WO/2022/174628A1 |
The invention relates to a method for co-producing adipic acid and cyclohexanone oxime from cyclohexane. The method comprises: (1) subjecting cyclohexane and NO x to oxidation nitration to generate adipic acid, nitrocyclohexane, a nitrog...
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WO/2022/160169A1 |
A bimetallic catalyst, a preparation method therefor and the use thereof in the preparation of a polyether polyol. A new 3-OP tetradentate ligand bearing 1 P and 3 Os is coordinated with a metal to form a tetradentate chelate, which is t...
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WO/2022/146324A1 |
This invention relates to the synthesis of pyrimidine-4 (1H)-one derivatives from Meldrum's acid, carbonyl compounds (aldehyde/ketone), and guanylhydrazone derivatives and tautomers, enantiomers, and salts thereof.
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WO/2022/140654A1 |
The present disclosure relates to compositions and methods related to bicyclo[2.2.1] heptanamine-containing compounds and salts thereof.
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WO/2022/126942A1 |
The present invention relates to the field of synthesis and preparation of medical intermediates. Disclosed is a synthesis method for a medical intermediate cyclopropyl-containing chiral amine hydrochloride. According to the present inve...
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WO/2022/110930A1 |
The present invention provides a method for ammoximation of macrocycloalkanone, comprising the following steps: adding hydrogen peroxide, ammonia water, a hydroxylamine stabilizer, an oximation catalyst, a solvent, and a macrocycloalkano...
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WO/2022/073525A1 |
A method and device for integrating an ammoximation reaction and separation. In the method, titanium-silicon molecular sieve is used as a catalyst; an ammoximation reaction of a ketone, hydrogen peroxide and ammonia is carried out to gen...
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WO/2022/069553A1 |
The invention relates to a method for producing benzaldehyde oximes of the general formula (I) and to the use thereof as important precursors for the synthesis of agrochemical and pharmaceutical active substances.
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WO/2022/064454A1 |
The present invention discloses a process for the synthesis of compound of formula (VII) or a salt thereof, wherein, R, R1, R2, R3, R4a and R4b are as defined in the detailed description. The process further comprises the synthesis of an...
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WO/2022/034426A1 |
The present invention relates to a process for the preparation of a key intermediate and other intermediates useful for the synthesis of Siponimod, a drug used for the treatment of multiple sclerosis. Object of the invention are also sai...
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WO/2021/239568A1 |
The present invention relates to a process for the preparation of substituted 4-(N'-hydroxy- carbamimidoyl)benzoic acids, which can be obtained by nitrilase catalyzed hydration of substituted terephthalonitriles of formula (II) in an aqu...
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WO/2021/212460A1 |
Disclosed by the present application is a method for autocatalytic preparation of 2,5-furandicarboxaldehyde oxime. The method for the autocatalytic preparation of the 2,5-furandicarboxaldehyde oxime comprises: reacting 2,5-furandicarboxa...
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WO/2021/208202A1 |
The present invention provides a micro-interface enhanced cyclohexanone ammoximation reaction system and method. The system comprises an oximation reactor, a reaction clear liquid buffer tank, a tail gas absorption tower, and a micro-int...
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WO/2021/208201A1 |
The present invention provides an external micro-interface ammoximation reaction system and method. The external micro-interface ammoximation reaction system comprises an oximation reactor, a reaction clear liquid buffer tank, a tert-but...
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WO/2021/208199A1 |
The present invention provides a reaction system and method for ammoximation and tert-butyl alcohol recovery. The reaction system comprises an oximation reactor, a reaction clear liquid buffer tank, a tail gas absorption tower, a tert-bu...
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WO/2021/208200A1 |
The present invention provides a built-in micro-interface ammoximation reaction system and method, the system comprising an oximation reactor, a reaction supernatant buffer tank, a tert-butanol recovery tower, an extraction tank, a water...
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WO/2021/190567A1 |
Disclosed in the present invention are a diphenyl sulfide ketone oxime ester compound, a preparation method therefor, a composition and use thereof. A diphenyl sulfide ketone oxime ester photoinitiator has the characteristics of high sen...
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WO/2021/171301A1 |
A process for preparation of 3-Trifluoromethyl acetophenone oxime of formula I comprising the steps of: a) Reacting an isomeric mixture of halo benzotrifluoride with Mg metal in an organic solvent in presence of a catalyst to obtain a Gr...
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WO/2021/122955A1 |
The invention concerns a method for preparing a mixture containing cyclohexanol and cyclohexanone, comprising the step of hydrogenating cyclohexyl hydroperoxide in cyclohexane in the presence of a Raney nickel catalyst to give cyclohexan...
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WO/2021/114218A1 |
Provided are mycosporine-like amino acids Porphyra-334 and Shinorine and a method for extracting Porphyra-334 and Shinorine from seaweeds. The method comprises the following steps: leaching, flocculating, filtering, performing chromatogr...
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WO/2021/117053A1 |
The present invention relates to an improved process for preparing aldoximes of formula (I) with high purity and high yield. The improved process for preparing aldoxime is fast, simple, highly efficient, and reproducible. The improved pr...
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WO/2021/096811A1 |
Disclosed herein are tucaresol derivative compound and composition containing the same. Also disclosed herein are methods of enhancing immune response in a subject by administering the tucaresol derivative compound or by co-administering...
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WO/2021/082278A1 |
Disclosed are a class of fluorine-containing α-diimine nickel complexes for preparing a polyolefin elastomer and intermediates thereof. The class of complexes have a single catalytic active center, the molecular weight of a polymer can ...
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WO/2021/084185A1 |
The invention relates to a method for producing a compound comprising at least one imine group, the method comprising a step of reaction between a first compound comprising at least one amine group and a second compound comprising at lea...
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WO/2021/035176A1 |
The invention provides a compound of formula (I): wherein R1, R2, and R3 have any of the values described in the specification, as well as compositions comprising a compound of formula (I), methods for preparing compounds of formula (I),...
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WO/2021/000467A1 |
Disclosed are a fluorescent compound for the detection of isocyanate substances, a preparation method therefor and the use thereof as a test-paper-type detection probe. The fluorescent compound is 2,4-di(((4'-(diphenylamino)-[1,1'-biphen...
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WO/2020/240391A1 |
The present invention discloses an improved process for the preparation of bromo-formimine compounds. More particularly, the present invention discloses an improved process for the preparation of bromo-formimine compounds, wherein bromin...
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WO/2020/202940A1 |
Provided is a catalytic mixture with sufficient catalytic efficiency, wherein pressure loss is small when the catalytic mixture fills a flow reactor and a reactive solution is caused to flow therethrough, and the catalytic efficiency and...
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WO/2020/169047A1 |
Disclosed in the present invention is a 1,1-dicyanohydrazone compound having a novel structure, the structure being as shown in general formula I. See the description for the definitions of each substituent in the formula. The compound o...
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WO/2020/132819A1 |
Disclosed is a method for preparing (1R,3S)-3-aminocyclopentanol hydrochloride. The method comprises using amide formed by chiral carboxylic acid and hydroxylamine as a chiral source, quickly obtaining a chiral Diels-Alder reaction produ...
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