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WO/2022/061918A1 |
The present application relates to the technical field of chemical pharmacy, and in particular, to a preparation method for 3,5-dihalobenzotrifluoride, comprising: using 3,5-dihalo-4-aminotrifluorotoluene as a raw material, and subjectin...
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WO/2022/063767A1 |
The present invention relates to novel compounds, pharmaceutical compositions comprising such compounds and their use for treating, alleviating or preventing diseases or disorders relating to the activity of potassium channels.
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WO/2022/045960A1 |
The present invention relates to a method for separating p-dichlorobenzene from a mixture composed of at least chlorobenzene and dichlorobenzene isomers by a combination of distillation and crystallization, wherein the distillation is pe...
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WO/2022/026789A1 |
Provided herein are compositions and methods for delivering pharmaceutical agents. In particular, provided herein are topical formulations of resatorvid for use in treating and preventing skin pathologies.
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WO/2022/014356A1 |
The present invention provides a method for producing an anion exchange resin, which is able to produce an electrolyte membrane that has excellent mechanical characteristics (strength). When an anion exchange resin, wherein a hydrophob...
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WO/2021/251035A1 |
The present invention functions as a photoacid generator; and this photoacid generator provides a chemically amplified photoresist composition by being combined with a component that is a resin, the solubility of which in an alkali is in...
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WO/2021/185072A9 |
Disclosed in the present invention are a crystal form of aromatic vinyl derivatives, and a preparation method therefor and the use thereof. Specifically disclosed in the present invention are crystal form A, crystal form B and crystal fo...
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WO/2021/220800A1 |
As a catalyst for realizing high palladium dispersity and a stable, electron-rich palladium site, there is provided a catalyst in which particles of an intermetallic compound of palladium and zirconium are supported on zirconium carbide ...
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WO/2021/181416A1 |
The present invention relates to a process for the preparation of l-bromo-2,4,5-trifluorobenzene from 2,4,5-trifhioroaniline or sulfate salt thereof. The present invention also relates to a process for the preparation of 1,2,4-trifluorob...
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WO/2021/182238A1 |
The present invention improves the dissolution rate of 1,1'-bi-2-naphthol in ethyl acetate. The 1,1'-bi-2-naphthol composition according to an embodiment includes racemic 1,1'-bi-2-naphthol, and toluene and/or chlorotoluene, the Hazen co...
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WO/2021/177290A1 |
A method for producing a mono-cross-coupled aromatic compound (3-1), said method comprising: preparation of an aromatic compound (1) that has at least two leaving groups; preparation of a compound (2) that is capable of undergoing a cros...
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WO/2021/177144A1 |
Provided is a method which makes it possible to more safely produce a naphthyl silole to be used as a GNR raw material, by: producing a lanthanoid complex of a compound represented by formula (1) by reacting the compound represented by f...
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WO/2021/152435A1 |
The present invention relates to a process for preparation of 5-bromo-1,2,3-trichlorobenzene of formula (I) in simple, economical manner with high yield. The 5-bromo-1,2,3-trichlorobenzene of formula (I) is used in preparation of 1-(3,4,...
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WO/2021/152598A1 |
Derivatives of 1-phenyl-tetralin were found to be pesticidally active having high efficiency against several Basidomyceta, Ascomycota and Heterokontophyta fungi as well as protobacteria of the genus Pseudomonas.
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WO/2021/103614A1 |
The present invention relates to the field of preparation methods for and uses of compounds, and relates in particular to a preparation method for and use of N-bis(dimethylamino)-1,3-dimethylimidazoline, having the chemical formula: C9H2...
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WO/2021/097475A1 |
The present invention is directed at the synthesis and characterization of recrystallized HI-6 dimethylsulfate (DMS). The method can comprise dissolving HI-6 DMS in an alkyl-based glycol and adding an antisolvent to recrystallize HI-6 DM...
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WO/2021/085131A1 |
The present invention provides an organic compound having: main skeleton having a fused ring structure; an electron withdrawing group joined to the main skeleton; and an electron donating group joined to the main skeleton. The organic co...
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WO/2021/078217A1 |
Disclosed are a 2,8-disubstituted tetracene derivative represented by formula (I), a preparation method therefor, and the use thereof. The compound can be used for preparing an organic semiconductor device, particularly an organic field-...
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WO/2021/065450A1 |
An active light sensitive or radiation sensitive resin composition which contains (A) an acid-decomposable resin, (B) a compound represented by general formula (b1), and (C) a compound represented by general formula (c1), wherein the rat...
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WO/2021/060305A1 |
The present invention addresses the problem of providing a catalyst filling method which prevents deterioration of the catalyst performance in cases where a solid acid catalyst is used in a fixed-bed reactor through which a fluid passes....
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WO/2021/036060A1 |
A process comprises the manufacture or preparation of fluorinated benzene, in particular monofluorobenzene, in a vapor-phase fluorination process. For example, the process can comprise a batch or continuous manufacture or preparation of ...
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WO/2021/029395A1 |
A compound which has one or more halogen atoms and an unsaturated double bond. A method for producing an iodine-containing vinyl monomer, said method comprising: (a) a step for preparing an iodine-containing alcoholic substrate having a ...
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WO/2021/017362A1 |
Provided is a dechlorination method of a chloro-substituted aromatic compound (R 1-X m) using copper as a catalyst, comprising using R 1-X m as a substrate, adding R 2(OH) n, an alkaline substance with a pH value greater than 7, and a co...
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WO/2020/262134A1 |
The present invention addresses the problem of providing a purification method for an actinic ray-sensitive or radiation-sensitive resin composition which can be used to form a pattern in which defects are inhibited. The present inventio...
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WO/2020/246566A1 |
Provided are: a main chain scission-type resist material that can satisfy roughness in particular; and a composition containing the same. In the main chain scission-type resist material, the principal agent is directly decomposed by bein...
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WO/2020/243572A2 |
The present invention relates to antibodies against influenza neuraminidase, compositions containing the antibodies and methods of using the antibodies.
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WO/2020/232256A1 |
Compounds are provided that are useful as immunomodulators. The compounds have the Formula (I) including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1a, R1b, R1c, R1d, R2a, R2b, R3, R3a, R4, R6, R7, R8, A, Z, X1...
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WO/2020/175495A1 |
Provided is a method for producing a salt by reacting M+X- with YH so as to generate XH and M+Y-, and then removing the generated XH so as to obtain M+Y-. M+X- is a salt of a cation represented by M+ and an anion represented by X-. M+Y- ...
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WO/2020/164217A1 |
Disclosed is a process for the manufacture of fluoroaryl compounds and derivatives thereof, in particular of fluorobenzenes and derivatives thereof, and especially wherein said manufacture relates to an environmentally friendly productio...
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WO/2020/162408A1 |
The present invention has the effect of making it possible to produce 1,1,1-trifluoro-2,2-bisarylethane efficiently by a simple procedure by condensing a mixture of fluoral and hydrogen fluoride with an aryl compound under anhydrous cond...
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WO/2020/118564A1 |
Compounds are provided having the structure of Formula (I) : (I) or a pharmaceutically acceptable isomer, racemate, hydrate, solvate, isotope, or salt thereof, wherein X1, X2, and R1 are as defined herein. Such compounds function as thyr...
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WO/2020/114813A1 |
The invention relates to a process for the preparation of 5-bromo-1,3-dichloro-2-fluoro-benzene by diazotization and reduction of 6-bromo-2,4-dichloro-3-fluoro-aniline, which is obtained by bromination of 2,4-dichloro-3-fluoro-aniline, w...
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WO/2020/079079A1 |
The present invention relates to co-crystals comprising levothyroxine and a dicarboxylic acid, preferably L-tartaric acid or oxalic acid, and processes for the preparation thereof. Furthermore, the invention relates to a pharmaceutical c...
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WO/2019/245409A1 |
The invention relates to a method for producing halogen-polyfluorobenzenes, wherein the halogen is chlorine and/or bromine, by reacting potassium salts of polyfluorocarboxylic acids with perhalogenalkanes or bromine as halogenating agent...
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WO/2019/189037A1 |
Provided is a fused-ring compound which exhibits excellent charge transport capacity. This fused-ring compound is represented by formula (1) having a specific structure.
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WO/2019/163395A1 |
This porous carbon material has a specific resistance value of 10 to 10,000 Ω·cm at a packing density of 0.4 g/cc.
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WO/2019/159596A1 |
Provided is a method for preparing a coupled body represented by general formula (3), the coupled body being obtained by reacting a compound represented by general formula (1) and a compound represented by general formula (2) in the pres...
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WO/2019/150327A1 |
An opto-electronic device includes a substrate, a first electrode disposed over the substrate, a semiconducting layer disposed over the first electrode, a second electrode disposed over the semiconducting layer, the second electrode havi...
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WO/2019/147934A1 |
A method of treating Parkinson's Disease, Huntington's Disease and the like, diseases with abnormal dopamine-neurotransmission, using small molecules administered systemically that penetrate into the central nervous system to inhibit the...
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WO/2019/143299A1 |
The present invention relates to hyper-branched compounds, a method of synthesizingthe hyper-branched compounds and applications of the hyper-branched compounds. Thehyper-branched compounds of the present invention include hyper-branched...
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WO/2019/118768A1 |
A method to increase the efficiency of myotube generation and maturation from pluripotent stem cells comprising: (a) differentiating pluripotent stem cells to myogenic progenitors; and (b) terminally differentiating said myogenic progeni...
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WO/2019/108773A1 |
The present invention relates to substituted stilbenes and dienones which exhibit unexpected dual activity, as inhibitors of NFκB and as agonists (activators) of Nrf2. In particular, these compounds show dual activity and makes them par...
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WO/2019/083997A1 |
The present disclosure relates to compounds that bind to flavin-containing enzymes and inhibit mitochondrial function, referred to herein as mitoflavoscins. Methods of screening compounds for mitochondrial inhibition and anti-cancer prop...
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WO/2019/079609A1 |
Provided herein are novel bioavailable dual inhibitors capable of inhibiting both soluble epoxide hydrolase (sEH) and phosphodiesterase 4 (PDE4), and methods of using the same.
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WO/2019/052236A1 |
The present invention pertains to the field of fine chemicals and related chemical technologies and provides a preparation method for a butadiene derivative. Phenylacetylene and derivatives thereof are used as raw materials and react in ...
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WO/2019/039759A1 |
The present invention relates to a method for producing mono-iodobenzene and mono-iodobenzene produced therefrom, the method enabling the selective recovery of gas-state iodine that is lost when regenerating a catalyst used in a reaction...
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WO/2019/031743A1 |
The present specification provides a method for preparing a styrene monomer, comprising, as a step of preparing a styrene monomer of chemical formula 2 by reacting a compound represented by chemical formula 1 in the presence of phosphori...
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WO/2019/004021A1 |
The purpose of the present invention is to control the alignment of liquid crystal molecules of a liquid crystal display element not having an alignment film, by using a non-colored alignment-control-layer-forming monomer, and to provide...
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WO/2018/225087A1 |
The present invention discloses a cobalt compound of formula (I), a process for the preparation and use thereof. The present invention further relates to a pharmaceutical composition and a method inhibition of Tau Aggregation in a subjec...
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WO/2018/179482A1 |
The purpose of the present invention is to provide an organic electroluminescence element which has a long life and emits blue light having high color purity. A dibenzo[c, g]fluorene compound including a specific substitution group of th...
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