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JP2021028295A |
To provide an optically active trans-astaxanthin derivative or a salt thereof having excellent antioxidant activity and excellent water solubility, safety, etc., and to provide a composition containing the high-purity derivative or a sal...
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JP6833698B2 |
Provided are urea manufacturing method and apparatus, which can increase the conversion ratio into urea and to reduce the consumption of steam. The temperature of the reactor is increased by introducing the entire amount of raw material ...
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JP6826367B2 |
Provided herein are modified amino acids comprising an azido group, polypeptides, antibodies and conjugates comprising the modified amino acids, and methods of producing the polypeptides, antibodies and conjugates comprising the modified...
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JP6821592B2 |
A urea synthesis reactor is provided that comprises a casing extending along an axis and a first and a second inlet tube inserted through respective through openings of the casing and respectively connected, inside the casing, to a light...
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JP6814794B2 |
The present invention relates to a novel compound showing leukotriene B4 receptor 2 (BLT2) inhibitory activity and a pharmaceutical composition, for preventing or treating inflammatory diseases, comprising same as an active ingredient. T...
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JP2021501198A |
The present invention relates specifically to compounds, methods, systems, and compositions for the maintenance, growth, and proliferation of hematopoietic stem cells from one or more sources of CD34 + cells. Sources of this CD34 + cell ...
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JP6813485B2 |
Amino acids present in domains of an umami taste receptor are described herein, wherein the amino acids interact with at least one nucleotide derivative and/or at least one transmembrane compound that potentiates, modulates, increases, a...
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JP6802897B2 |
A process for producing a NOx reductant AUS 32 solution (diesel exhaust fluid), including at least the mixing of water and a particulate composition including (i) urea and an additive comprising component (ii). The additive component is ...
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JP6804580B2 |
The present invention relates to novel amide derivatives of N-urea substituted amino acids, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of the N-formyl peptide ...
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JP6802207B2 |
The present invention relates to a photosensitive resin composition, which has chemical resistance and has excellent pot life by preventing the reaction of a carboxyl group-containing photosensitive resin and an epoxy compound during sto...
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JP6798592B2 |
Provided is a liquid crystal aligning agent which forms a liquid crystal alignment film that exhibits good adhesion to a substrate and a sealing agent. A liquid crystal aligning agent that contains a polyimide precursor that is obtained ...
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JP2020176126A |
To provide a method for producing an organic compound that causes a reaction between functional groups to occur without using solvent.This invention relates to a method for producing an organic compound that causes a reaction between fun...
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JP6776227B2 |
The present invention relates to compounds that are inhibitors of the orexin-1 receptor. The compounds have the structural formula I defined herein. The present invention also relates to processes for the preparation of these compounds, ...
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JP6762306B2 |
Method and apparatus that enable the more efficient manufacture of urea are provided. Before unreacted substances are removed from a urea synthesis solution obtained from a stripper, the urea synthesis solution is placed under pressure r...
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JP6746614B2 |
The present invention provides a urea compound or a pharmacologically acceptable salt thereof that has a formyl peptide receptor like 1 (hereinafter may be abbreviated as FPRL1) agonist effect, a pharmaceutical composition containing the...
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JP2020524178A |
The present invention relates to novel double regulators of farnesoid X receptor (FXR) and soluble epoxide hydrolase (sEH). The regulator of the present invention was designed to provide a compound having dual activity as an agonist of F...
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JP2020097564A |
To provide modulators of the prostacyclin (PGI2) receptor useful for treatment of disorders related to the PGI2 receptor.Compounds, for example, compounds of chemical formula (XIIIa) and pharmaceutical compositions thereof are useful in ...
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JP6703127B2 |
The invention relates to the integrated synthesis of NH3 from syngas with the separation of CO2 and to the synthesis of urea from the NH3 and the separated CO2.
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JP2020075867A |
To obtain steam condensate and steam having a relatively high utility value from low-pressure steam condensate which is generated when consuming low-pressure steam in a purification step and/or a concentration step.A urea production meth...
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JP2020513473A |
The present invention relates to the field of heat-thickeners. More specifically, the present invention describes the general formula (IV) (in the formula, R).a, Rb, Rc, Rd, R1', R2', R3, R3', R4, R4', R5, R5', R6, R6', Z1, Z1', Z2, And ...
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JP6686174B2 |
The present invention relates to a novel N-acylurea derivative and the use thereof for the prevention or treatment of cardiovascular disease, and more particularly to a novel N-acylurea derivative, a pharmaceutical composition for preven...
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JP2020059693A |
To provide a simple, cost-effective and improved method for synthesizing apronal and an intermediate alkyl 2-isopropyl-4-pentenoate used in the synthesis of allylisopropylacetylurea of apronal.There is provided a method including a step ...
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JP6653253B2 |
The present invention relates to derivatives of N-urea substituted amino acids, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of the N-formyl peptide 2 receptor.
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JP6653388B2 |
Processes for separating carbon dioxide from CO2-containing gases and an apparatus for providing carbon dioxide for the synthesis of urea.
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JP6636133B2 |
The present invention relates to compounds according to general formula (I) which are metabolically robust analogues of bioactive lipid mediators derived from omega-3 polyunsaturated fatty acids (n-3 PUFAs). The present invention further...
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JP2020011923A |
To provide a compound that has strong adhesion even in a water wet state and has excellent durability against air oxidation, and a resin composition, a coating agent, and an ink composition including the same.The present invention provid...
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JP2020500863A |
Here we describe novel conjugates containing inhibitors covalently attached to macromolecules (eg nanoparticles, polymers, proteins) (eg PSMA inhibitors, eg gastrin-releasing peptide receptor inhibitors) and metal chelators. To do. Such ...
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JP2020007317A |
To provide pyrrolysine analogs useful in bioconjugation processes.The invention provides, e.g., pyrrolysine analogs represented by the formula in the figure. (X=O or S; Y=CH, NH, O, or S; Z=CH, CH-NH, CH-OH, NH, O, or S; FG=azide, alkene...
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JP6629422B2 |
The present disclosure relates to a corrosion resistant duplex stainless steel (ferritic austenitic alloy) which is suitable for use in a plant for the production of urea; and uses thereof. The disclosure also relates to objects made of ...
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JP6627835B2 |
The present invention relates to a compound represented by the general formula (I) (wherein the definition of each group has the same meaning as described in the specification). The compound is useful as preventive and/or therapeutic age...
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JP2019203023A |
To provide a phenoxyurea compound excellent in pest control activity such as insecticidal and acaricidal activity, and nematocidal activity, excellent in safety, and capable of being industrially advantageously synthesized, and a pest co...
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JP6607924B2 |
Disclosed are compounds of Formulas (I), (II), (III), (IV), and (V):and/or a salt thereof, wherein R1 is —OH or —OP(O)(OH)2, and X1, X2, X3, R2, R2a, Ra, Rb, and Rc are defined herein. Also disclosed are methods of using such compoun...
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JP6596522B2 |
Method for the production of urea from ammonia and carbon dioxide in a urea plant containing a high-pressure synthesis section with a horizontal pool condenser, wherein the method comprises exchanging heat from a high pressure process me...
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JP6595078B2 |
The present disclosure provides a compound represented by Formula (I) and a pharmaceutically acceptable salt which are effective as a dopamine reuptake inhibitor and a method of using the compound.
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JP2019178128A |
To provide a novel oxygen isotope-labeled compound in which a carbonyl site is substituted with heavy oxygen, and a method for producing the same.The present invention provides a method for producing an oxygen isotope-labeled compound re...
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JP2019528309A |
The present disclosure is in the field of polymers and pharmaceuticals / antibacterial agents. The present disclosure provides compounds based on SNAP (Synthetic Novel Antibacterial Polymer) technology, compositions and methods for contr...
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JP6587648B2 |
The present invention provides compounds of formula (I), and pharmaceutical compositions thereof.
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JP6585328B1 |
A compound represented by the formula (I) or a salt thereof. [Chemical 1]In equation (I), R1Is a hydrogen atom, a substituted or unsubstituted C1-6 alkyl group, etc., and R2Is a hydrogen atom, or a C1-6 alkyl group, R3And R4Are independe...
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JP6571650B2 |
There are provided pyrrolysine analogs of the formulae (X), (I), (II), (V), (VI), (VII) and (VIII), in which the a, b, d, X, Y, Z, FG, R, R1, R2 and R3 are as defined in the claims, which are useful in bioconjugation processes and mutant...
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JP2019523245A |
The present invention provides for the use of compounds of formula I as ligands for orphan nuclear receptors and in the prevention or treatment of diseases associated with orphan nuclear receptors. [Chemical 118]
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JP2019522627A |
Compounds that regulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing the compounds, and growth disorders such as cancer, viral infections and / or using the compounds of t...
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JP6541570B2 |
Method for the production of urea from ammonia and carbon dioxide in a urea plant containing a high-pressure synthesis section with a horizontal pool condenser, wherein the method comprises exchanging heat from a high pressure process me...
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JP2019518753A |
The present invention selectively obtains the urea of cis-1,3-diaminocyclohexane by reacting a mixture of cis and trans-1,3-diaminocyclohexane with carbon dioxide or a reactive carbonic acid derivative, cis- and trans. Regarding the meth...
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JP2019515901A |
The present invention is a tool as a phenylurea derivative useful for the treatment of inflammatory diseases, a pharmaceutical composition containing the phenylurea derivative, and a modulator of the N-formyl peptide receptor (FPR) conta...
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JP6526275B2 |
Compounds of formula (I): where n, R1, R4a, R4b, R5, R7 and R8 are defined herein, or pharmaceutically acceptable salts thereof, are described herein. The disclosed compounds have activity as SHIP1 modulators, and thus may be used to tre...
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JP6503479B2 |
A process and a device for the production of ammonia at different pressure levels may involve removing gases that are inert (inert gases) or harmful with regard to ammonia synthesis from the process in a process step before the ammonia s...
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JP6496689B2 |
The present invention relates to novel amide derivatives of N-urea substituted amino acids, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of the N-formyl peptide ...
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JP6475301B2 |
The present invention relates to a polyisocyanate composition comprising, on the basis of the total mass of the polyisocyanate composition, 97 weight % or more of a polyisocyanate, and 2.0 mass ppm or more and 1.0×10mass ppm or less of ...
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JP6474736B2 |
Antibiotically active compounds characterized by general formula (I), wherein X1, BB, BC, BD, BE and X2 are building blocks with D1, D2, D3, D4 or D5 being linkers which include carbon, sulphur, nitrogen, phosphor and/or oxygen atoms and...
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JP6452731B2 |
The present disclosure provides a compound represented by Formula (I) and a pharmaceutically acceptable salt which are effective as a dopamine reuptake inhibitor and a method of using the compound.
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