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JP5852469B2 |
A liquid crystal composition containing a liquid crystal molecule, a compound represented by the formula (1), and a compound represented by the formula (2) can provide a film with a reduced haze.
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JP5829520B2 |
Provided are 4-modified colchicine compounds and medicines using the same. Specifically provided are colchicine derivatives represented by general formula (1), salts thereof, and solvates of the same. In general formula (1), R1 is a halo...
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JP5828434B2 |
Vertical reactor for effecting gas-liquid biphasic reactions, comprising a plurality of perforated plates, superimposed and suitably spaced between each other along the vertical axis, wherein a dividing septum is positioned vertically in...
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JP5823582B2 |
Process for the production of urea-comprising particles, wherein the urea-comprising particles are produced in a pelletizer, comprising a feeding device, a belt and a device to remove the formed pellets from the belt, by feeding a urea-c...
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JP5806765B2 |
Prostate-specific membrane antigen (PSMA) binding compounds having radioisotope substituents are described, as well as chemical precursors thereof. Compounds include pyridine containing compounds, compounds having phenylhydrazine structu...
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JP2015196675A |
To provide a water-absorbing resin crosslinking agent that has an excellent safety property, can efficiently crosslink water-absorbing resin at a low-temperature and produce an absorbent having high water-absorption capability, and to pr...
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JP5800863B2 |
The invention relates to novel material, forming supramolecular structures below its transition temperature, which contains at least one C=O and/ or C=S group and at least one N-H, O-H and/ or S-H group and wherein the material has the s...
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JP2015182965A |
To provide a method realizing high-yield production of an aromatic urea compound at relatively low temperature without using highly toxic compounds as ingredients and without corrosive or toxic gas by-products.A method of producing an ar...
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JP5790645B2 |
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JP5782331B2 |
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JP5773877B2 |
Provided are compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions.
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JP2015145392A |
To provide compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using the compounds and compositions.This invention r...
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JP2015522546A |
The present invention relates to inhibitors of the activity of the mitochondrial electron transport chain complex (III) and its use in the treatment and / or prevention of cancers that present tumor-initiating cells. The present inventio...
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JP5753170B2 |
The present invention relates to a method for contemporaneously recovering ammonia and carbon dioxide from an aqueous solution thereof, possibly comprising their condensates, in a synthesis process of urea, characterized in that it compr...
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JP5752239B2 |
The present invention relates to a compound of Formula I, or an isomer, pharmaceutically acceptable salt and solvate thereof. The present invention also relates to a composition comprising a compound of Formula I, or an isomer, pharmaceu...
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JP5753380B2 |
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JP5744886B2 |
The invention relates to cyclopentanecarboxamide derivatives of formula 1, to their use as Fatty Acid Synthase inhibitors, to methods for their therapeutic use and to pharmaceutical compositions containing them, wherein R1, R2, R3, LO, W...
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JP2015518484A |
The present invention relates to novel therapeutic compounds, especially for use as biologically active derivatives and agents, such as for the treatment of atrial fibrillation. Provided are compounds having the following general formula...
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JP2015120658A |
To provide: poly(meth)acrylates which have excellent oil repellency at high temperature while having perfluoroalkyl groups with 5 or less carbon number in side chains; and (meth)acrylates as monomers for providing such poly(meth)acrylate...
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JP5738433B2 |
An operation method of a urea production plant including multiple systems that can prevent a considerable decrease in urea production even when an ammonia synthesis facility is shut down. At a time of producing urea from CO2 and ammonia,...
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JP5733340B2 |
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JP5730190B2 |
The present invention provides an inhibitor of PAI-1 comprising, as an active ingredient, a compound represented by Formula (I) or a salt thereof, or a solvate thereof. The present invention also provides a pharmaceutical composition hav...
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JP5715870B2 |
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JP5711350B1 |
To provide an economical method capable of simultaneously producing a substituted urea and a carbamate compound from an amine with a high yield and reusing an ionic liquid catalyst containing indium a plurality of times. Amine, carbon di...
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JP5710494B2 |
A process for the preparation of an allophanate of one or more identical or different isocyanates, compositions obtained by the process, and uses of the compositions are disclosed. The process comprises reacting an isocyanate with at lea...
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JP5701832B2 |
The present invention provides a method represented by Scheme 1: wherein X represents I, Br, Cl, alkylsulfonate, or arylsulfonate; Z represents optionally substituted aryl, heteroaryl or alkenyl; L represents hydrogen or a negative charg...
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JP2015063557A |
To provide novel 4-dedimethylamino tetracycline compounds which can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms.The present invention provides substituted tetracycline com...
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JP5693565B2 |
The invention relates to the use of O-imino-iso-urea compounds as source of radicals to polymerizable compositions comprising these O-imino-iso-urea and to new O-imino-iso-urea compounds. The O-Imino-isoureas compounds are compounds of t...
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JP5684726B2 |
The present invention provides compounds (n-3 PUFA derivatives) of formula (I): that modulate conditions associated with cardiac damage, especially cardiac arrhythmias.
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JP2015044829A |
To provide a compound having biaryl phosphodiesterase-4 (PDE4) inhibitory action useful for treatment and prevention of stroke, myocardial infraction and cardiovascular inflammatory diseases.There is provided a biaryl compound having at ...
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JP5681985B2 |
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JP2015506349A |
The compound of structure (I): or its stereoisomer, tautomer, pharmaceutically acceptable salt or prodrug, in structure (I), R1, R2, R3, R4, R8. , R9, R10, R11, R12, A1, A2, X, Y and Z are as defined herein. The use of such compounds as ...
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JP5674635B2 |
Substituted 4-aminocyclohexane derivatives (I) and their stereoisomers or their mixtures, free compounds and/or salts are new, where (I) excludes 4-(dimethylamino)-1-methyl-4-p-tolylcyclohexyl acetate. Substituted 4-aminocyclohexane deri...
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JP5671558B2 |
Methods and processes for preparation and production of deuterated É-diphenylurea are disclosed. Especially, a kind of deuterated É-diphenylurea compounds which can inhibit phosphokinase and the preparation method of N-(4-chloro-3-(tri...
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JP5667044B2 |
The present invention relates to substituted phenoxybenzamide compounds of general formula (I): in which R1, R2, R3, R4, R5, X, R6 and q are as defined in the claims, to methods of preparing said compounds, to pharmaceutical compositions...
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JP5662432B2 |
A device for evaporating a urea-water solution includes a delivery duct for the urea-water solution. The delivery duct extends through at least a first zone and a second zone for the introduction of heat energy. The zones can be heated s...
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JP5650432B2 |
This invention relates to a method to modulate exogenous gene expression in which an ecdysone receptor complex comprising: a DNA binding domain; a ligand binding domain; a transactivation domain; and a ligand is contacted with a DNA cons...
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JP5647790B2 |
The present invention relates to a process for producing an N-carbamoyl-tert-leucine, characterized in mixing tert-leucine with an isocyanic acid compound while a pH of the mixture is kept at not less than 8.0 and not more than 13.5, whe...
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JP5648083B2 |
A pest control agent containing a compound represented by the following Formula (1), wherein A represents a carbon atom, a nitrogen atom, or the like, K represents a non-metal atom group necessary for forming a cyclic linking group deriv...
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JP5646595B2 |
Solid polymerizable diacetylenic monomer compositions, including compositions co-crystallized from a diversity of solvent systems under diverse cooling conditions, can exhibit diffraction patterns associated with the color development re...
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JP2014532079A |
The present invention provides novel phenicol derivatives, their use for the treatment of mammalian infections, pharmaceutical compositions containing these novel compounds, and methods of making these compounds.
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JP5633980B2 |
This invention relates to a process for co-producing methanol and ammonia, wherein a syngas mixture consisting essentially of carbon monoxide (CO), carbon dioxide (CO2) and hydrogen (H2) is first partially reacted in a methanol once-thro...
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JP5632857B2 |
Provided is a complex of hydrogen peroxide and at least one compound represented by Formula I: wherein X is: -C(R3)3, -C=C(R3), -O(R3), -N(R3)2, or -S(R3); and R1, R2, and R3 are each independently selected from H, alkyl, alkenyl, alkyny...
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JP2014210774A |
To provide modulators of a prostacyclin (PGI2) receptor useful for treatment of disorders related to the PGI2 receptor.Compounds specified in the figure and pharmaceutical compositions thereof are useful in the treatment of pulmonary art...
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JP5606737B2 |
Compounds of Formula (Ia)wherein R is a C6-C12 substituted or unsubstituted aryl, a C6-C12 substituted or unsubstituted heteroaryl, a C1-C6 substituted or unsubstituted alkyl or -NR'R',Q is C(O), O, NR', S, S(O)2, C(O)2 (CH2)pY is C(O), ...
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JP2014527043A |
The present invention provides new compounds of formula I, II or III, which have Src homology-2 containing protein tyrosine phosphatase-1 (SHP-1) agonist activity. Also provided are treatment methods using the compounds of formula I, II ...
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JP5603180B2 |
A heat curable epoxy composition comprising the contact product of an epoxy resin, an epoxy curing agent and an accelerator for the epoxy curing agent, the curing agent or the accelerator comprising a urea compound which is the reaction ...
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JP2014185149A |
To provide a biaryl phosphodiesterase-4 (PDE4) inhibitor useful for treatment and prevention of stroke, myocardial infarction, cardiovascular inflammatory diseases and central nervous system disorders.There is provided a biaryl compound ...
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JP5600355B2 |
The present invention provides a pest control agent, acaricide or fungicide that contains, as the active ingredient thereof, at least one type of compound selected from the aryloxyurea compounds represented by formula (V) (wherein R 1 to...
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JP5599318B2 |
Allophanate-group-containing polyisocyanates based on isophorone diisocyanate, represented by formula (I) wherein Ra, k, m, (k +m), Y, Xi, n and Rb are as defined, and to their use.
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