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WO/2007/022901A1 |
The present invention relates to a novel process for the preparation of compounds of the formula (I) by reacting in a first step amino alcohols of the formula (II) with chlorosulfonic acid to give sulfuric acid esters of the general form...
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WO/2007/013533A1 |
Disclosed is a solid polymer electrolyte material for solid polymer fuel cells which has high ion exchange capacity and low resistance. This electrolyte material has a higher softening temperature than the conventional electrolyte materi...
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WO/2007/014273A2 |
Compounds, pharmaceutically acceptable salts, stereoisomers and prodrugs thereof, that are ER ligands and particularly to such compounds that are ER beta-selective and/or ER beta-specific ligands. Compounds herein include certain compoun...
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WO/2007/013532A1 |
A compound containing two fluorosulfonyl groups, which are groups convertible to sulfo groups; an intermediate therefor; and processes for producing these compounds with high productivity. Also provided are: a fluorosulfonylated polymer ...
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WO/2007/013974A2 |
The present invention provides synthetic processes for the preparation of sulfonyl halides of Formula Ar- (R) 2-SO2-X and sulfonamides of Formula Ar-(R)2-SO2- NR4R5, where the constituent variables are as defined herein, that are useful ...
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WO/2007/010356A2 |
The invention relates to a process for the preparation of compounds of formula (I) wherein Q1 is a group selected from formulae (II) & (III) and a group *-NR6 -Q2-A or, if appropriate, their pharmaceutically acceptable salts and/or isome...
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WO/2007/009798A2 |
A process of producing a compound of formula (3), wherein R1 is a C1-5alkyl group, R2 is a halogen atom, a C1-5 alkyl group, a C2-5 alkenyl group, a C2-5 alkynyl group, a C1-5 alkyl group, a C1-5 alkoxy group, a nitro group, or a hydroxy...
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WO/2007/006387A2 |
The invention relates to a method for producing onium-alkylsulfonates by reacting an onium halogenide or carboxylate with a symmetrically substituted dialkyl sulphite or with a asymmetrically substituted dialkyl sulphite at temperatures ...
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WO/2007/006300A1 |
The invention relates to producing monomer, oligomer and polymer non-fluorinated, partially fluorinated or perfluorinated sulphonic acids by reacting halogenated, low-molecular weight, oligomer or macromolecular arenes with (hydrogen) su...
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WO/2007/004077A2 |
The invention includes an improved process for producing tamsulosin comprising reacting 5-(2-aminopropyl)-2-methoxybenzenesulfonamide with 2-(o-ethoxyphenoxy)ethyl bromide in an organic phosphite solvent to obtain tamsulosin. Optically p...
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WO/2007/005430A1 |
The present application provides a process to produce fluorinated vinyl ether by reacting a 2-alkoxypropionyl fluoride with a metal carbonate under anhydrous conditions in a stirred bed reactor at a temperature above the decarboxylation ...
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WO/2006/137473A1 |
A process for producing an aromatic sulfonic acid compound, comprising sulfonating a compound having at least one aromatic ring with the use of any of compounds of the formula (1) as a sulfonating agent. This provides a process for produ...
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WO/2006/136919A1 |
The present invention relates to a method for the preparation of Florfenicol from Fluoroamine compound, namely (1R,2S)-1-[4-(methylsulfonyl)phenyl]-2-amino-3-fluoro-1-prop
anol (II), by reaction with dihaloacetic acid ester in an organic...
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WO/2006/137774A1 |
There is provided a process for the preparation of a compound of formula I, which process comprises: (a) reaction of a compound of formula II, HO-D-NH2 II with a compound of formula III, followed by (b) reaction of the intermediate of fo...
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WO/2006/134212A2 |
The invention relates to a process for the production of tamsulosin hydrochloride crystals where the crystal size distribution is controlled by controlling the temperature where hydrochloric acid is added to the reaction mixture.
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WO/2006/131757A1 |
The present invention relates to a process for preparing certain sulphonamide intermediates useful in the preparation of HIV inhibitors and to the crystal forms thereof.
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WO/2006/133330A1 |
Hydrofluoroalkanesulfonates of the general formula R-O-CXH-CX2-SO3M, where R is selected from the group consisting of alkyl groups, functionalized alkyl groups, and alkenyl groups; X is selected from the group consisting of hydrogen and ...
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WO/2006/133331A1 |
A process for manufacture of hydrofluoroalkanesulfonic acid with at least one hydrogen bonded to the carbon atom adjacent to the carbon atom bonded to the sulfonic acid group comprising: contacting a fluoroolefin with sulfite in an aqueo...
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WO/2006/127184A1 |
The present invention is directed to a process for the preparation of sulphonylimine derivatives [particularly those of formula (XII)] and sulphamide derivatives [particularly those of formula (I)]. The process comprises reacting an alde...
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WO/2006/120816A1 |
A process in which a functional molecule capable of ionic dissociation which is stable not only chemically but also thermally under operating conditions required for electrochemical apparatus, such as fuel cells, being suitable for use a...
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WO/2006/117662A2 |
The invention relates to processes for the preparation of polymorphic forms of (R)-(-)- tamsulosin. More particularly, it relates to the preparation of polymorphic forms of (R)-(-)- tamsulosin designated as Form I and II. The invention a...
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WO/2006/109570A1 |
Disclosed is a method for commercially advantageously producing 2-isopropenyl-5-methyl-4-hexen-1-yl 3-methyl-2-butenoate with high yield. Specifically disclosed is a method for producing 2-isopropenyl-5-methyl-4-hexen-1-yl 3-methyl-2-but...
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WO/2006/108883A1 |
The present invention relates to a method for preparing a highly soluble linear alkyl benzene sulphonate (LAS). Specifically, the method includes adding a hydrotropic composition before or after the sulphonation of the linear alkyl benze...
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WO/2006/106800A1 |
Disclosed is a method for producing a compound (III), a salt thereof or a solvate of them by reacting a compound (I), a salt thereof or a solvate of them with a compound (II) in a toluene solvent in the presence of an additive such as wa...
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WO/2006/106960A1 |
A disulfonyl fluoride compound is easily and efficiently produced through a coupling reaction. The compound is converted to produce a useful compound. A compound (1) in which Y is fluorine is subjected to a photocoupling reaction, while ...
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WO/2006/106244A2 |
The invention relates to a method for preparing a compound of formula (I) in which: R1, R2, R3, while being identical or different, are protective groups and Nu is a nucleophilic group, to a method in which a nucleophilic compound is rea...
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WO/2006/087166A1 |
Provided is a process for the preparation of N-monosubstituted β-aminoalcohol sulfonates of formula (Ia), (Ib) wherein R1 is C6-20 aryl or C4-12 heteroaryl, each optionally being substituted with one or more halogen atoms and/or one or ...
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WO/2006/072259A2 |
The quantitatively most important pathway for the excretion of cholesterol in mammals is the formation of bile salts (the conjugate bases of bile acids). The major bile salts are synthesized and secreted by as glycine or taurine conjugat...
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WO/2006/061549A1 |
A process for producing tamsulosin of formula (I) and pharmaceutically acceptable addition salts, thereof comprises the steps of : a) Reacting compound R,R-[2-(4-methoxy-phenyl)-1-methyl-ethyl]-(1-phenyl-ethyl)-a
mine of formula (II) or ...
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WO/2006/059700A1 |
Disclosed is a separating agent for asymmetric substances which has high separation performance. Specifically disclosed is a polysulfonamide derivative represented by the following formula (1) or (2). (In the formulae, R represents an op...
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WO/2006/051697A1 |
Disclosed is a method for producing a fluorine-containing fluorosulfonyl alkylvinyl ether represented by the following chemical formula: CF2=CFOCF2CF2SO2F which is characterized in that a fluorine-containing chlorosulfonyl alkylvinyl eth...
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WO/2006/052522A2 |
Disclosed are methods for making the phosphonium sulfonate salt of generic formula: (1): wherein each X is independently a halogen or hydrogen, provided that the molar ratio of halogen to hydrogen is greater than about 0.90; p is 0 or 1 ...
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WO/2006/042678A1 |
The invention relates to a method for cleaning 3-hydroxyamidinophenylalanine derivatives comprising the steps: (a) addition of an aromatic sulphonic acid to a solution of an optionally contaminated 3-hydroxyamidinophenylalanine derivativ...
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WO/2006/040131A1 |
The invention relates to a method for combining carbon-carbon bonds starting from a copper compound of an aryl, heteroaryl, alkene or alkine and an aryl, heteroaryl, alkene or alkine compound with a suitable nucleofuge. The copper compou...
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WO/2006/023611A1 |
The present invention provides method for making a compound of formula (1) comprising the steps of reacting compounds of formulas (2) and (3) to produce a compound of formula (4) wherein R1, R2, R3, R4 and R5 are defined as described her...
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WO/2006/019358A2 |
The present invention relates to a process for preparing Tamsulosin, an anti-benign prostatic hyperplasia drug, which comprises converting o-ethoxyphenoxyethanol to a corresponding sulfonate, and reacting the sulfonate with (R)-(-)-5-(2-...
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WO/2006/006156A2 |
The invention provides methods for detection of medical disorders, associated with cellular oxidative stress, cell degeneration and / or cell death. The invention further relates to compounds comprising a thiol (-SH) group, for detecting...
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WO/2006/004093A1 |
A process for industrially advantageously producing tamsulosin or a pharmacologically acceptable salt thereof, which are useful as a therapeutic agent for urination disorders accompanying prostatic hypertrophy. The process, which is for ...
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WO/2006/003795A1 |
A process which comprises using a stable Ru(salen)(CO) complex represented by the general formula (I) or an enantiomer thereof as the catalyst and by which optically active aziridines and amines can be produced enantioselectively with a ...
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WO/2005/123646A2 |
The production of fluoroorganic compounds in the form of amidoamines, quaternised compounds thereof, amides and ethers, guanidides, hydrazides, ureides, thioureides, perfluoropolyoxaalkylenesulfo- or perfluoropolyoxaalkylenecarboxylic ac...
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WO/2005/118529A2 |
This invention relates to a process for preparing optically active &agr -amino acid substrates which are used to make potent lethal factor (LF) inhibitors for the treatment of anthrax. This invention further relates to a process for synt...
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WO/2005/105737A1 |
The present invention relates to novel processes for the preparation of substituted tetralin and substituted indane derivatives. The present invention is further directed to novel processes for the preparation of intermediates in the pre...
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WO/2005/102993A1 |
A process for the purification of aqueous acid solutions which can dispense with the step of removing chloride ions and which is reduced in the damage to an ion exchanger (such as an ion-exchange column) and thereby permits repeated use ...
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WO/2005/100307A2 |
A method for making the phosphonium sulfonate salt of generic formula (1): wherein each X is independently a halogen or hydrogen, provided that the molar ratio of halogen to hydrogen is greater than about 0.90; p is 0 or 1 and q and r ar...
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WO/2005/095323A1 |
La présente invention concerne un procédé de préparation de composé ester activateur de blanchiment. Ce procédé consiste (A) à préparer un monoester d'acide gras, (B) à fabriquer un chloroformate par réaction de ce monoester d...
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WO/2005/092952A1 |
A process for sulfating alkoxylated amines, alkoxylated polyols, hydrophobic polyamine ethoxylate polymers, via the use of sulfuric acid.
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WO/2005/085187A1 |
Disclosed is a method for producing an &ohgr -fluorosulfonyl perfluoroalkyl vinyl ether represented by the general formula (2) below through specific steps (a)-(c) from an &ohgr -haloperfluoroalkyl sulfonyl fluoride represented by the ge...
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WO/2005/081777A2 |
Severely sterically hindered secondary aminoether alcohols are prepared by reacting an organic carboxylic acid or alkali metal salt of an organic carboxylic acid with a sulfonyl halide, a sulfuryl halide, a mixed sulfuryl ester halide or...
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WO/2005/082843A1 |
The present invention provides processes for the preparation of arylalkylsulfonyl halides and heteroarylalkylsufonyl halides of Formula: Ar-R-SO2-X, that are useful as intermediates in the preparation of pharmaceuticals.
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WO/2005/080323A1 |
The invention relates to an improved process for the manufacture of enantiomerically pure R-(+) or S-(+)-5-(2-aminopropyl)-2-methoxybenzene sulfonamide by resolution of (R,S)-5-(2-aminopropyl)-2-methoxybenzene sulfonamide with D-(-) or L...
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