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WO/2013/047162A1 |
Provided is a method for producing a chloroalkylsulfonyl chloride, by which a high-purity chloroalkylsulfonyl chloride can be obtained with high yield with high productivity. This method for producing a chloroalkylsulfonyl chloride is a ...
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WO/2013/040985A1 |
It is an object of the present invention to provide a sulfonic acid group- containing polymer and a sulfonic acid group-containing aromatic compound, which have excellent proton conductivity even under the low humidification condition, a...
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WO/2013/040768A1 |
The invention provides a method of making a sulfonic group-containing aromatic compound. The multi-substituted sulfonated aromatic compounds can be obtained by reacting an aromatic compound with fuming sulfuric acid having a sulfur triox...
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WO/2013/039584A1 |
Methods for converting an H2SO4 alkylation unit to an ionic liquid alkylation system configured for performing ionic liquid catalyzed alkylation processes may comprise connecting at least one component configured for ionic liquid catalyz...
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WO/2013/030035A1 |
Suggested is a process for preparing sulfates and/or sulfonates by adding sulfur trioxide to a compound comprising at least one hydroxyl function and/or at least one double bond, which is characterized in that (i) the reaction is perform...
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WO/2013/033022A2 |
This invention relates to methods for the production of sodium, potassium, rubidium, cesium, magnesium, manganese, cobalt, nickel, aluminum, copper (II) and zinc salts of 5-sulfoisophthalic acid. In addition, this disclosure describes ne...
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WO/2013/029431A1 |
Disclosed are tosylate salts of benzodiazepine derivatives, their polymorphic forms, preparation methods and uses thereof, in particular to a tosylate salt of 3-[(4S)-8-bromo-1-methyl-6-(2-pyridinyl)-4H-imidazo[1,2-a][1
,4]benzodiazepine...
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WO/2013/031849A1 |
Provided is a method for producing an organic compound having a sulfo group by efficiently hydrolyzing an organic compound having a fluorosulfonyl group through a fewer number of steps in such a manner that a waste solution is produced i...
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WO/2013/021309A1 |
The invention relates to a crystalline form of 2-chloro-N-{2-[3-(2-{[(4'-hydroxybiphenyl-3- yl)methyl]amino}-2-oxoethyl)phenyl]-1,1-dimethylethyl}acetam
ide, a process for preparing the same and its use in the preparation of the 2 ago...
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WO/2013/018848A1 |
Disclosed is a production method for fluoroalkanesulfonic acid, including: a step (1) in which concentrated sulfuric acid and/or oleum is reacted with fluoroalkanesulfonic acid salt to acid-separate same, and a reaction mixture including...
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WO/2013/018465A1 |
This method for producing a geminal difluoro compound comprises a step wherein a fluorine-containing enol sulfate ester is reacted with a fluorination agent (such as hydrogen fluoride or "a salt or complex composed of an organic base and...
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WO/2013/014267A1 |
A process is provided for preparing C8-C22 acyl amido compounds via reaction in a polyol (molecular weight 76 to 300) of interesterifying a fatty acid ester with an amino compound or salt thereof. The resultant mass of material will have...
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WO/2013/014265A1 |
A reagent composition for forming fatty acyl amido surfactants is provided which includes an alkali metal or alkaline earth metal salt of an amino compound; a polyol of molecular weight ranging from 76 to 300; and no more than 10% water.
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WO/2013/011485A1 |
The present invention relates to a process for the preparation of sulfonamides useful as retroviral protease inhibitors.
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WO/2013/010502A1 |
Disclosed are an acid addition salt of prasugrel, a preparation method therefor and a use thereof. The preparation method is: adding prasugrel and hydroxyl-substituted benzenesulfonic acid to an organic solvent, stirring and dissolving, ...
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WO/2013/000315A1 |
A guaiazulene derivative, a preparation method and a use thereof. The compound is highly stable and is applicable in treating gastric ulcer. [Formula I]
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WO/2013/002040A1 |
This process for producing fluorosulfuric acid aromatic-ring esters includes a step of reacting an aromatic-ring hydroxyl compound with sulfuryl fluoride (SO2F2) in the presence of a tertiary amine exclusive of pyridine and methylpyridin...
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WO/2012/174926A1 |
The present invention provides an N-substituted isopropyldimethyl azulene sulfonamide derivative as represented by formula (1), and preparation method and uses thereof. R1 is an alkyl, cycloalkyl, alkenyl, alkynyl, aryl, heteroaryl, amin...
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WO/2012/175935A1 |
A method of preparing a component of a personal care bar, the method comprising: (a) providing a composition comprising an isethionate surfactant at a temperature of at least 20˚C; (b) combining the composition comprising the isethionat...
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WO/2012/173235A1 |
A compound represented by formula (I) [wherein R1 represents a hydrocarbon group having 1-10 carbon atoms, and Z represents a hydrocarbon group having 1-10 carbon atoms or a cyano group, wherein R1 and Z may be bound to each other to for...
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WO/2012/171484A1 |
Disclosed is a substituted cyanoaniline compound or a salt thereof, wherein the compound has a structure represented by General Formula I. The compound of General Formula I has broad-spectrum fungicidal activity in the field of agricultu...
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WO/2012/173694A1 |
Embodiments are related to ionic liquids and more specifically to ionic liquids used in electrochemical metal-air cells in which the ionic liquid includes sulfonate ions as the anion.
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WO/2012/163799A1 |
The present invention relates to a novel enantioselective method of preparing (S)- and (R)-enantiomers of N-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-6-5 methoxyphenyl}-1-[2,3-dihydroxy-propyl]cyclopropanesulfonami
de, to novel inte...
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WO/2012/147944A1 |
The present invention provides a method for producing a compound represented by general formula (1) (wherein R1, R2, R3, R10-R14, A1-A3, n1 and n2 are as defined in the description), which is characterized by reacting a compound represen...
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WO/2012/147037A2 |
Isolation of Naphthalene Sulphonic Acid Compounds is achieved with acidification of alkali fusion mixture with dilute sulphuric acid to precipitation at the predetermined conditions temperature, time and p H and Naphthalene Sulphonic Aci...
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WO/2012/148624A1 |
Hydroxyamides are synthesized from esters. A process of making hydroxyalkyl amides comprises : reacting an ester with a hydroxyalkyl amine having the formula H2N-R3-OH wherein R3 is a substituted or unsubstituted C2 to C5 alkyl, in the p...
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WO/2012/142927A1 |
A method for purification of calcium ion channel blocker medicament of dihydropyridine type and pharmaceutically acceptable salts thereof through the ultrasonic crystallization technology and direct preparation of nanoparticles thereof.
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WO/2012/137813A1 |
Provided is a method for producing a bis(perfluoroalkanesulfone)imide salt by adding water and an alkali metal hydroxide to a salt containing the bis(perfluoroalkanesulfone)imide salt represented by the general formula (RfSO2)2NM (in the...
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WO/2012/136761A1 |
The present invention relates to a process for the preparation of the mono sodium salt of the derivative 3,5-diiodo-O-[3-iodo-4-(sulphooxy)phenyl]-L- tyrosine (T3S) by starting from the corresponding phenolic compound, in the presence of...
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WO/2012/132269A1 |
The present invention provides a novel diamine compound that contains a sulfonic acid group and is represented by formula (1), and a method for producing the same. This compound has a fluorene backbone including a sulfonic acid group or ...
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WO/2012/134464A1 |
Disclosed is a method for improving filtration in the preparation of an alkaline earth metal alkyltoluene sulfonate concentrate by selectively controlling the meta, ortho, para isomer distribution of the alkyl group of the alkyltoluene p...
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WO/2012/126630A1 |
The subject matter of the present invention relates to highly-concentrated compositions of salts of alkyl polyalkoxy sulphates, whereby in total at least 2/3 of all alkoxy unit of the alkyl polyalkoxy sulphates are propoxy units, a metho...
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WO/2012/126088A1 |
A method for preparing docosahexaenoic acid (DHA). The method comprises coupling a compound represented by Formula I with a compound represented by Formula II followed by partial hydrogenation to obtain a compound represented by Formula ...
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WO/2012/122667A1 |
Betaine surfactants of formula (I) and preparation methods and uses thereof are provided. The surfactants can depress the interfacial surface tension of crude oil till 10-3mN/m, have the capabilities of antiheating (130℃), antiminerali...
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WO/2012/117961A1 |
Obtain a compound [II] such as N, N-di(fluorosulfonyl)imide ammonium salt by reacting a compound [I] such as N, N-di(chlorosulfonyl)imide and NH4F(HF)p. Obtain a compound [IV] such as N, N-di(fluorosulfonyl)imide alkali metal salt by rea...
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WO/2012/118973A2 |
The claimed invention meets these and other objects by providing a method of preparing a metal salt of a dialkyl ester of 5-sulfoisophthalic acid. Broadly speaking, the method provides for the contacting of a dialkyl ester of 5-sulfoisop...
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WO/2012/112828A1 |
The invention is directed to mixtures comprising C10-C14 linear alkylphenyl sulfonates with alkyl groups having a biobased content of at least 50%. These C10-C14 linear alkylphenyl sulfonates are used in consumer product cleaning and per...
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WO/2012/110092A1 |
Pharmaceutically useful compounds of general formula (2) or of general formula (2-1) wherein R is hydrogen or a C1-C10 alkyl/aryl/aralkyl group, and R1 is a C1-C10 alkyl/aryl/aralkyl group, and Z is -0-, -S- or -NH- linkage. Processes fo...
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WO/2012/108284A1 |
A compound [I] such as an N-(chlorosulfonyl)-N-(fluorosulfonyl)imide ammonium salt is reacted with hydrogen fluoride to produce a compound [II] such as an N,N-di(fluorosulfonyl)imide ammonium salt. The resulting compound [II] is reacted ...
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WO/2012/103799A1 |
Disclosed are (2R,3R)-3-(3-substituted phenyl)-2-methyl-n-pentanamide compounds shown as formula I, their preparation methods thereof, wherein the substituents are described in the description, and their uses in the manufacture of Tapent...
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WO/2012/105586A1 |
This perfluorobutane sulfonyl fluoride has a perfluorosulfolane content of 100 ppm or less on a mass basis. This potassium perfluorobutane sulfonate salt has a potassium 1,1,2,2,3,3,4,4-octafluorobutane sulfonate salt content of 100 ppm ...
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WO/2012/099184A1 |
A fluoroamine can be produced by: protecting an amino group of an amino alcohol with a nitrobenzenesulfonyl group, thereby converting into a protected amino alcohol (amino group protection step); causing the protected amino alcohol to re...
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WO/2012/097550A1 |
Cyclohydrocarbyl formamide derivatives of general formula (I), preparation methods and uses thereof are provided. The present cyclohydrocarbyl formamide derivatives of general formula (I) target on the auxiliary protein Vif (Virus infect...
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WO/2012/097351A1 |
Described herein are molecules useful to affect cancer cells, along with related methods. The present compounds, formulations, kits and methods are useful for diagnostic, therapeutic and research. STAT3 inhibitors, particularly LLL12, ar...
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WO/2012/084794A1 |
The invention relates to a process for preparation of radiopharmaceutical precursors, and in particular protected amino acid derivatives which are used as precursors for production of radiolabelled amino acids for use in in vivo imaging ...
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WO/2012/084831A1 |
The invention relates to a process for preparation of radiopharmaceutical precursors, and in particular protected amino acid derivatives which are used as precursors for production of radiolabelled amino acids for use in in vivo imaging ...
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WO/2012/078521A1 |
A process comprising contacting deionized water with one or more Strecker sulfonation reaction products of one or more halogenated alkyl ethers in the presence of sulfite, wherein the one or more Strecker sulfonation reaction products ea...
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WO/2012/073249A1 |
Disclosed herein is an efficient and economical process for the preparation of 3-Benzyloxybenzenethiol of formula-I which is a key intermediate for the preparation of pharmaceutical drugs. R' is hydrogen, halogen, trihalomethyl, lower al...
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WO/2012/070793A2 |
The present invention relates to an improved method for purifying a sulfonated aromatic monomer. The method for purifying a sulfonated aromatic monomer is an economical method which is capable of obtaining the sulfonated aromatic monomer...
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WO/2012/069004A1 |
Disclosed are a preparation method for a key intermediate of tapentadol: (1R, 2R)-1-ethyl-2-methylbenzene ethane compound, and a method for applying the key intermediate in the preparation of tapentadol and a derivative thereof.
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