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WO/2016/081683A2 |
The invention describes methods of preparation and compositions of plasticizers. The ketal diester products described are useful as components of polymer compositions. The products are excellent plasticizers for a variety of polymers, su...
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WO/2016/080484A1 |
Provided is a novel unsaturated cyclic carbonate having a fluorinated alkyl group. The present invention is a compound represented by general formula.
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WO/2016/071921A2 |
A new route for preparation of 3:2,4-bis-(3,4- dimethylbenzylidene) sorbitol [DMDBS] has been disclosed which is comprising: bromination of o-xylene to obtain a mixture of 4-bromo- o-xylene as a major product and 3-bromo-o-xylene; conver...
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WO/2016/066574A1 |
Disclosed are compounds of formula (I) which possess anthelminthic properties wherein the structural elements have the meaning as indicated in the description. Further disclosed are such compounds for the control, treatment and/or preven...
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WO/2016/062424A1 |
The present invention relates to a method for preparing a compound of formula (I), the substituent R3 having a specific meaning, to a mixture and to a corresponding application/use.
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WO/2016/063959A1 |
Provided is an antibody-drug complex having a linker of which the hydrolysis rate at a pH value in a weakly acidic in vivo environment can be controlled accurately. An antibody-drug complex having a cyclic benzylidene acetal linker, whic...
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WO/2016/054798A1 |
The present invention provides a preparation method for cyclic carbonate. The method comprises the following steps: cyclizing carbon dioxide and an epoxide in the presence of a main catalyst and cocatalyst, to obtain the cyclic carbonate...
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WO/2016/049774A1 |
Urea-based and bis-urea based compounds and analogues thereof are disclosed. These compounds are useful in the treatment of androgen-dependent diseases or disorders and androgen receptor-mediated diseases or disorders. Specifically, the ...
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WO/2016/045125A1 |
Disclosed are a compound of formula I or a pharmaceutically acceptable salt thereof, which inhibit HIF prolyl hydroxylase, their use for enhancing endogenous production of erythropoietin, and for treating conditions associated with reduc...
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WO/2016/045127A1 |
Disclosed are compounds of formula I or pharmaceutically acceptable salts thereof, which inhibit HIF prolyl hydroxylase, their use for enhancing endogenous production of erythropoietin, and for treating conditions associated with reduced...
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WO/2016/038543A1 |
The invention describes phospho-amino pincer-type ligands, metal complexes thereof, and catalytic methods comprising such metal complexes for conversion of carbon dioxide to methanol, conversion of aldehydes into alcohols, conversion of ...
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WO/2016/038627A1 |
The present invention relates to the process for the preparation of halogenated derivatives of aromatic ethers.
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WO/2016/035609A1 |
The present invention provides a method for producing a benzaldehyde in which an amino group is bonded in the 2 position, a halogeno group or an alkoxy group is bonded in the 3 position, and a hydrogen atom, an alkyl group, a halogeno gr...
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WO/2016/034751A1 |
Diseases and pests pose a serious problem in the field of agriculture. The present invention proposes a new compound of formula (I) having biocidal activity, isolated from the fermentation product of endophyte fungi of the Guignardia sp ...
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WO/2016/030510A1 |
The present invention relates to heteroaromatic chalcone derivatives, particularly the compounds of formula (I) as described and defined herein, pharmaceutical compositions comprising these compounds, and their medical use, including the...
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WO/2016/022519A1 |
The present invention relates to stereochemically defined polypropionates and methods for preparing and using the same. The stereochemically defined polypropionates may be useful in the synthesis of natural products and/or natural produc...
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WO/2016/019907A1 |
According to embodiments of present disclosure, a method to produce a compound of Formula (19) is provided. Using this method, the compound of Formula (19) may be produced effectively.
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WO/2016/008010A1 |
The present invention relates to anti-tropomyosin compounds, processes for their preparation, and methods for treating or preventing a disease or disorder, such as a proliferative disease (preferably cancer), using compounds of the inven...
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WO/2016/009793A1 |
A high-purity vinylene carbonate in which the content of chlorine impurities that are to be detected by the oxyhydrogen flame combustion-ion chromatography method is substantially zero, characterized by having a Hazen unit color number o...
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WO/2016/006003A1 |
The present invention relates to the development of novel one-pot process for the preparation of fatty cyclic carbonates from unsaturated fatty derivatives using t-butyl hydroperoxide (TBHP; 70 wt.% in water) and carbon dioxide (CO2) thr...
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WO/2015/182732A1 |
Provided are an apparatus and a method for continuously producing a cyclic carbonate economically advantageously and with high industrial productivity, whereby it becomes possible to produce the cyclic carbonate without requiring the use...
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WO/2015/177537A1 |
The present invention relates to a novel process for the synthesis of polycyclic carbamoyl pyridone derivativesof formula (B): wherein Ar, W1, W2, W3, X, Y and Z are as defined in the specification; and to novel chemical intermediates fo...
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WO/2015/176833A1 |
The present invention relates, in particular, to a mixture containing or at least mainly consisting of (alpha,alpha-(4aR,5R,7aS,9R)-octahydro-2,2,5,8,8,9a-hexameth
yl-4H-4a,9-methanoazuleno(5,6-d)-1,3-dioxole) of formula (Ia) and (beta,b...
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WO/2015/158603A1 |
The invention relates to a compound of formula (I) or a salt thereof, where the symbols and indices are defined in the specification. The compounds of formula (I)are useful for combating animal pests and for combating parasites in and on...
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WO/2015/155659A1 |
The present invention relates to a process for preparing cyclic acetals having general formula (I) wherein Y and Y', equal to or different from each other, are selected from H and a group OR, R being a linear or branched alkyl containing...
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WO/2015/152182A1 |
Provided is a hydrophilic polymer derivative having an acetal linker, of which the rate of hydrolysis in weakly acidic pH environments in a living organism can be reliably controlled, and which does not release low molecular weight speci...
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WO/2015/150543A1 |
The present invention relates to a binder system that contains a resin component and a curing agent component, the resin comprising at least one compound having at least two cyclic carbonate groups and at least one compound having at lea...
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WO/2015/132080A1 |
The present invention suggests 2-hydroxyethyl 2-oxo-1,3-dioxolane-4-carboxylates of formula (I): (I) wherein one of R1 and R2 can be hydrogen. In particular, R1 and R2, if not hydrogen, and in each case independently of one another, are ...
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WO/2015/124272A1 |
The invention relates to new conjugated semiconducting polymers containing thermally cleavable side groups. The thermally cleavable side groups are selected from among carbonate groups and carbamate groups. By thermally cleaving side gro...
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WO/2015/123486A1 |
The present disclosure provides a dialkyl carbonate prepared from a methyl branched primary C16 - C17 alcohol. The dialkyl carbonate is prepared by transesterifying a reactant dialkyl carbonate with the methyl branched primary C16 - C17 ...
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WO/2015/088273A9 |
The present invention relates to sulfamate derivative compounds and a composition for treating and/or alleviating pain containing the sulfamate derivative compounds or a pharmaceutically acceptable salt thereof as an active ingredient. M...
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WO/2015/101909A1 |
The present invention relates to a process for the production of olefinic compounds that can be used for the production of detergents, additives, lubricants and/or plastic materials, or components which can be used in the field of oil ex...
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WO/2015/101294A1 |
The present invention provides compounds of general formula I, isomers thereof, non-toxic pharmaceutically acceptable salts or solvates thereof. The compounds have remarkably strengthened analgesic activity, reduce the acute toxicity obv...
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WO/2015/103508A1 |
Described are RORγ modulators of the formula (I), or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein all substituents are defined herein. Also provided are pharmaceutical compositions ...
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WO/2015/101636A1 |
The present invention relates to a process for preparing sordidin, comprising a step of preparing 4-(2-ethyl-1,3-dioxolan-2-yl)pentan-2-one by means of a reaction in which 2-ethyl-2-(pent-4-en-2-yl)-1,3-dioxolane is oxidized in the prese...
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WO/2015/093532A1 |
The present invention pertains to a nonaqueous electrolyte which improves electrochemical characteristics when a capacitor device is used under high temperatures and high voltages, and which not only maintains capacity after storage in h...
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WO/2015/091494A1 |
The invention relates to a compound of formula (I) wherein and A1 and A1' are independently from each other a linear or branched alkylene radical comprising from 1 to 20 carbon atom(s); A2 is in particular a linear or branched alkylene r...
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WO/2015/095879A1 |
The invention relates to a method for producing 2-methyl-1,3-dioxolane from a polyester solid state polymerization system. The method comprises using an acid catalyst to effectuate the conversion of acetaldehyde present within the system...
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WO/2015/093580A1 |
[Problem] To provide a non-aqueous electrolyte solution having an excellent cycle capacity retention rate and low-temperature resistance characteristics, and a non-aqueous electrolyte rechargeable battery that uses the non-aqueous electr...
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WO/2015/089137A1 |
The present invention is directed to acylguanidines which are inhibitors of tryptophan hydroxylase (TPH), particularly isoform 1 (TPHl), that are useful in the treatment of diseases or disorders associated with peripheral serotonin inclu...
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WO/2015/081610A1 |
Degradable isocyanate compounds, methods for making these compounds, and uses of these compounds for preparing degradable cross-linked polymers and composite materials are provided.
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WO/2015/067110A1 |
The present invention discloses a method for preparing the ticagrelor intermediate 2-[[(3aR,4S,6R,6aS)-6-aminotetrahydro-2,2-dimethyl-4H-cyclop
enta-1,3-dioxan-4-yl]oxy]ethanol (intermediate C). The preparation method uses (1R,2R,3R,4R)-...
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WO/2015/067111A1 |
The present invention discloses a method for preparing the ticagrelor intermediate 2-[[(3aR,4S,6R,6aS)-6-aminotetrahydro-2,2-dimethyl-4H-cyclop
enta-1,3-dioxan-4-yl]oxy]ethanol (intermediate C). The method uses (1R,2R,3S,4S)-rel-1,2:3,4-...
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WO/2015/064764A1 |
Provided is an aryloyl(oxy or amino)pentafluorosulfanylbenzene compound having pharmacological action. The present invention relates to an aryloyl(oxy or amino)pentafluorosulfanylbenzene compound represented by general formula (A-I), a p...
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WO/2015/061518A1 |
Compounds of Formula I with activity against HIV, including pharmaceutical compositions and methods for using these compounds in treating human immunodeficiency virus (HIV) infection, are set forth: Formula :(I)
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WO/2015/051921A1 |
The invention provides an efficient and high yielding process for preparing TH-302, comprising at least one step wherein a dioxolane intermediate is generated in an aqueous layer, resulting in a synthesis that is amenable to scale up con...
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WO/2015/042685A1 |
Compounds which inhibit the formation and/or accumulation of RNA foci, such as those due to polynucleotide repeats (e.g., trinucleotide repeats) are described herein. Also described herein are uses of such compounds, such as for the inhi...
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WO/2014/207766A9 |
The present invention disclose a simple and high yielding process of Oxone-acetone mediated metal free syn-dihydroxylation of benzo fused olefins of formula (II) to obtain library of dioxolo compounds of formula (I). The invention furthe...
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WO/2015/032357A1 |
Zanamivir, a Zanamivir intermediate compound (formula 2), and a preparation method therefor. The preparation method is method 1 or 2. Method 1 comprises the following steps: compound 3 undergoes a reaction to remove a protecting group so...
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WO/2015/027833A1 |
The present invention relates to compounds represented by general formulas I, IIa, lib and III and preparation method therefor. Ar1 is substituted o-arylene or o-heteroarylene; Ar2 is bis(o-arylene) or bis(o-heteroarylene) connected in v...
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