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WO/2022/129933A1 |
Disclosed are compounds of the formula (I) and pharmaceutically acceptable salts thereof: (I) wherein Ring A, Ring B, Ring C, R1, R2, R3, R4, R5, L, m, n, and p are as defined herein. The compounds are modulators of G-protein coupled rec...
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WO/2022/122975A1 |
The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt and/or solvate thereof, for use as a drug, especially as an antibiotic. The present invention also relates to a pharmaceutical composition c...
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WO/2022/121317A1 |
Disclosed is a 1,1'-biphenyl-2,6-diphenolic compound and the use thereof. The 1,1'-biphenyl-2,6-diphenolic compound is a new compound, and has good biological activity. By means of in vitro tumor cell activity experiments, it was found t...
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WO/2022/112351A1 |
The present invention relates to malonamide compounds of the formula (I) wherein the variables are as defined in the claims and the description, and to compositions comprising these compounds. The invention also relates to the use of sai...
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WO/2022/105986A1 |
The present invention relates to novel physiological cooling agents, cooling agent mixtures containing said novel substances, mixtures of cooling agents with flavours, the use of said cooling agents and objects and final preparations for...
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WO/2022/106452A2 |
The invention relates to a new type of physiological cooling agents, coolant mixtures containing said agents, mixtures of the coolants with flavors, the use of said cooling agents, and consumer products and final preparations containing ...
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WO/2022/108984A1 |
The invention relates in particular to methods and intermediates for the synthesis of Compound 1 that inhibits MCL1 and is useful in the treatment of cancers.
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WO/2022/104113A1 |
The disclosure provides recording materials including mono- or poly-phenyl-core derivatized monomers and polymers for use in volume Bragg gratings, including, but not limited to, volume Bragg gratings for holography applications. Several...
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WO/2022/101275A1 |
The invention is directed to a process to continuously react a gaseous mixture of an epoxide compound and carbon dioxide in the presence of a heterogeneous catalyst at a pressure of between 0.1 and 0.4 MPa in one or more reactors to a li...
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WO/2022/094711A1 |
Disclosed is a process of preparation of a compound of formula 13, and intermediates prepared and used in the preparation of the compound of formula 13.
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WO/2022/091123A1 |
The present invention discloses compounds for inhibition of uncontrolled cell proliferation particularly cancer stem cells. Particularly, the invention relates to compounds of Formula (I) to (IV) for the treatment of cancer.
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WO/2022/078462A1 |
Glutamine analogs are provided, a composition containing the glutamine analogs and the use thereof.
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WO/2022/078416A1 |
Glutamine analogs, a composition containing the glutamine analogs and the use thereof.
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WO/2021/179638A9 |
Disclosed are a purification method for electronic-grade ethylene carbonate, and a purification apparatus thereof. The method comprises the following steps: S1: seeding ethylene carbonate having a purity of 99.90%-99.98%; S2: heating to ...
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WO/2022/057734A1 |
The present invention relates to the technical field of organic chemical engineering, and in particular to a key intermediate for synthesizing prostaglandin compounds and a preparation method therefor. When applied to the synthesis of pr...
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WO/2022/053696A1 |
The present invention provides a novel group of active peptide compounds based on the psychoactive safrylamine compounds MDMA, MDA, MMDA-2, and MDAI. Thereby, the invention provides for improved pharmacokinetic properties during uptake o...
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WO/2022/054987A1 |
The present invention relates to a pharmaceutical composition for treating and/or alleviating a psychiatric disorder comprising a sulfamate derivative compound and/or a pharmaceutically acceptable salt thereof as an active ingredient. Fu...
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WO/2022/049036A2 |
The present invention relates to the field of perfumery. More particularly, it concerns valuable new chemical intermediates for producing perfuming ingredients. Moreover, the present invention comprises also a process for producing compo...
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WO/2022/045231A1 |
This ester compound is represented by formula (1) [wherein R1 to R24 are each independently a hydrogen atom, a halogen atom, a hydrocarbon group, or a heteroatom-containing hydrocarbon group; R1 to R10, R23, and R24 may be bonded to each...
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WO/2022/041426A1 |
Provided in the present invention are a micro-interface preparation system and method for cyclic carbonate, the micro-interface preparation system comprising: a stirring kettle and a carboxylation reaction kettle, the stirring kettle and...
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WO/2022/040747A1 |
The present invention relates to compounds that have zinc and/or iron ionophore activity and their use in treating diseases that are modulated by reducing zinc and/or iron. In particular embodiments, the compounds are compounds of formul...
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WO/2022/041425A1 |
Provided are a reinforced micro-interface preparation system and method for a cyclic carbonate. Said preparation system comprises: a stirring kettle, a first carboxylation reaction kettle and a second carboxylation reaction kettle. The s...
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WO/2022/040788A1 |
Anti -cancer, chemotherapeutic, or antiproliferative compositions comprising, as an active ingredient, a compound of formula (I0), or a salt, or prodrug thereof: and an anti-cancer, chemotherapeutic, or antiproliferative compound (A) or ...
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WO/2022/038171A1 |
There are disclosed psychedelic and entactogen compounds, the use of such compounds in the treatment of diseases associated with a serotonin 5-HT2 receptor, pharmaceutical compositions such as tablet compositions and kits containing the ...
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WO/2022/024928A1 |
The present invention addresses the problem of providing an actinic-ray-sensitive or radiation-sensitive resin composition capable of forming patterns having excellent LWR performance. Also provided are a resist film, a pattern formation...
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WO/2022/025242A1 |
The present invention provides a novel compound that can be used as a lactate dehydrogenase inhibitor and as an active ingredient of pharmaceuticals such as antiepileptic agents and anticancer agents, in particular, a novel compound havi...
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WO/2022/016345A1 |
Disclosed is an application of a composition for preventing and/or eliminating platelet aggregation in an in vitro blood sample. The composition comprises at least one compound selected from the group consisting of formula (I) and a salt...
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WO/2022/009025A1 |
The purpose of the present invention is to provide: a nonaqueous solvent which has high heat resistance and is able to be used in a wide temperature range; a secondary battery; and a vehicle. A nonaqueous solvent according to the present...
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WO/2022/009911A1 |
The present invention addresses the problem of providing a novel method for producing a 1,3-benzodioxole derivative. The method comprises a novel chlorination reaction of a benzene ring which gives a good yield and a small amount of impu...
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WO/2022/002380A1 |
The present invention primarily relates to novel processes for preparing cis-cedrandiol. Moreover, the present invention relates to a novel compound of formula (X), as described herein, preferably of formula X' or - particularly preferab...
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WO/2021/257020A1 |
Within the scope of the invention, 15 novel 3-[2-(1,3-benzodioxole-5-yl)ethyl)]-6-aryl-7H-1,2,4-triazolo
[3,4-b]-1,3,4-thiadiazine derivatives were synthesized. The cytotoxic and apoptotic effects of some synthesized compounds in human l...
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WO/2021/249928A1 |
The present invention relates to the use of strobilurin type compounds of formula I and the N-oxides and the salts thereof for combating phytopathogenic fungi containing an amino acid substitution F129L in the mitochondrial cytochrome b ...
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WO/2021/241246A1 |
Provided are a radiation-sensitive resin composition capable of exhibiting adequate levels of sensitivity, LWR performance, and CDU performance, and a method for forming a pattern. This radiation-sensitive resin composition contains a so...
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WO/2021/237681A1 |
Provided is a method for degrading epoxy resins by enzymatic route, in particular by adding an epoxy resin in a solvent followed by treatment with a glutathione S-transferase. A method for recycling a composite material comprising epoxy ...
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WO/2021/220648A1 |
Provided are a method for forming a resist pattern and a radiation-sensitive resin composition which, even when a next-generation exposure technology is applied thereto, have excellent performances concerning sensitivity during exposure ...
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WO/2021/209486A1 |
The present invention relates to new herbicidally active pyrroline-2-ones according to general formula (I) or agrochemically acceptable salts thereof, and the use of these compounds for controlling weeds and weed grasses in plant crops.
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WO/2021/202986A1 |
The disclosure provides therapeutic compounds, compositions (e.g., therapeutic agents or medicaments) and methods for preventing or treating mitochondrial disease such as Friedreich's ataxia in a mammalian subject, reducing risk factors,...
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WO/2021/192439A1 |
The purpose of the present invention is to provide: a compound which enables a liquid crystal composition to achieve a high voltage holding ratio (VHR); a liquid crystal composition which contains this compound; and a liquid crystal disp...
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WO/2021/193717A1 |
The present invention pertains to: a fluorine resin that includes a residue unit represented by formula (1), and an end group represented by formula (2); and a fluorine resin that includes a residue unit represented by formula (1) and ha...
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WO/2021/179049A1 |
The present invention relates to the treatment of disorders associated with oxidative stress including neuropathic pain and small synthetically derived compounds for treating such disorders.
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WO/2021/161083A1 |
The present disclosure provides a process of preparation of compounds of Formula I comprising the step of : reacting an alkylenedioxybenzene compound of Formula II with an acyl halide of Formula III in presence of a solvent, wherein the ...
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WO/2021/153782A1 |
Provided is a method for controlling Phakopsora pachyrhizi which has an amino acid substitution F129L in the mitochondrial cytochrome b protein. According to the present invention, the compound represented by formula (I) [in the formula,...
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WO/2021/153124A1 |
Provided are a radiation-sensitive resin composition, a resist pattern formation method, and a radiation-sensitive acid generator, with which it is possible to form a resist pattern having good sensitivity to light exposure and having ex...
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WO/2021/144162A1 |
The present invention relates to a process for preparing cyclic carbonates with an exocyclic vinylidene group by reacting a propargylic alcohol with CO2 in the presence of a silver catalyst having at least one bulky ligand and a lipophil...
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WO/2021/140761A1 |
The purpose of the present invention is to provide a radiation-sensitive resin composition and a resist pattern formation method, which enable formation of a resist pattern having excellent LWR performance and CDU performance and having ...
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WO/2021/132640A1 |
Provided is a method for stabilizing a perfluorodioxolane compound, said method including causing a quinone compound to be present within a composition that includes the perfluorodioxolane compound, wherein the perfluorodioxolane compoun...
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WO/2021/132693A1 |
[Problem] To provide a curable composition containing (2-oxo-1,3-dioxolane-4-yl)methyl(meth)acrylate[glycerin carbonate(meth)acrylate], wherein a cured product thereof does not have a metal corrosion problem and has excellent water resis...
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WO/2021/126939A1 |
Disclosed is a method for depolymerization of polyester. The method includes (a) treating said polyester with methanol under conditions sufficient to depolymerize at least some of said polyester and form a reaction product that includes ...
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WO/2021/124158A1 |
The present invention is directed to an efficient process for preparing benzoxazole derivatives comprising the step of reacting a 4-Amino-3-hydroxybenzoic acid compound of Formula III with a 3,5-Dichlorophenyl ortho ester compound of For...
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WO/2021/123116A1 |
The present invention relates to a compound represented by the following formula (I): A[B-(C)v]w, wherein A is a photoprotective moiety, B is a linker, C is a functional group, v is an integer from 1 to 2000, and w is an integer from 1 t...
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