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WO/2017/065457A1 |
The present invention relates to a microorganism having an L-threonine producing ability, and a method for producing L-threonine using the same.
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WO/2017/059626A1 |
The present invention discloses use of an enzyme pair consisting of an aminotransferase and an isomerase in the catalytic formation of L-allo-Ile, the aminotransferase is DsaD represented by SEQ ID NO.7 or MfnO represented by SEQ ID NO.5...
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WO/2017/055754A1 |
The invention relates to a method for producing L-methionine by carrying out an enzyme reaction between an L-methionine precursor, dimethyl disulfide (DMDS) and a reducing organic compound.
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WO/2017/055518A1 |
The present disclosure relates to methods for producing an amide compound from a nitrile compound using a dried biocatalyst which has been pre-treated with a buffer, wherein the dried and pre-treated biocatalyst has improved properties a...
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WO/2017/055755A1 |
The invention relates to a method for producing L-methionine by carrying out an enzyme reaction between an L-methionine precursor, dimethyl disulfide (DMDS) and hydrogen.
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WO/2017/051875A1 |
Provided is a compound represented by formula (I) or a salt thereof (in formula (I): R1 and R2 each represent hydrogen, a C1-5 straight-chain or branched alkyl group, a C1-5 straight-chain or branched alkoxy group, or a C1-5 straight-cha...
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WO/2017/053328A1 |
Methods of screening cancerous cells for nutritional weaknesses and methods of treating cancer nutritionally are disclosed. Certain cancers depend on being supplied with one or more nutrients that are non-essential for normal cells. In p...
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WO/2017/043915A1 |
The present invention pertains to: a novel variant polypeptide having efflux activity of O-phosphoserine (OPS) which is an L-cysteine precursor; a polynucleotide encoding the polypeptide; an OPS-producing microorganism expressing the pol...
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WO/2017/040958A1 |
Systems, methods, and host cells utilizing a PopQC construct for enhancing product biosynthesis by exploitation of non-genetic cell-to-cell variation, wherein the PopQC construct includes at least a product-responsive biosensor and a sel...
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WO/2017/036740A1 |
The present invention provides a recombinant cell genetically engineered to produce an increased amount of 5-aminovalerate compared to its wildtype. The invention further relates to a method for preparing 5-aminovalerate, the method comp...
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WO/2017/038793A1 |
The present invention provides a method for manufacturing fermented soybean that contains a high level of γ-aminobutyric acid and isoflavone agylcone and that is readily edible with little bitterness. The present inventors devised a man...
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WO/2017/033464A1 |
A method for producing an objective substance such as phytosphingosine and sphinganine using yeast is provided. An objective substance is produced by cultivating yeast having an ability to produce the objective substance and modified so ...
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WO/2017/034164A1 |
The present invention relates to a Corynebacterium sp. microorganism having an L-lysine producing ability and an L-lysine producing method using the same.
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WO/2017/031838A1 |
Disclosed is a method for producing L-ornithine by whole-cell biotransformation using recombinant Bacillus subtilis, wherein the method comprises constructing Bacillus subtilis 168 engineering bacteria which express arginase originated f...
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WO/2017/034165A1 |
The present invention relates to Corynebacterium sp. microorganisms having an L-lysine-producing ability and a method for producing L-lysine using the same.
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WO/2017/034343A1 |
The present application relates to a microorganism having L-leucine productivity and a method for preparing L-leucine using same and, more specifically, to a Corynebacterium glutamicum mutant, which has a tolerance to L-leucine and a der...
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WO/2017/033463A1 |
A method for producing an objective substance such as sphingoid bases and sphingolipids using yeast is provided. An objective substance is produced by cultivating yeast having an ability to produce the objective substance in a culture me...
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WO/2017/033134A1 |
The present invention provides a process for the preparation of enantiomerically pure (R)- 1-(1-naphthyl)ethylamine of formula (IIa) by treating 1-acetylnaphthalene of formula (I) with R-selective transaminase enzyme in presence of amino...
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WO/2017/033965A1 |
Provided is a method for producing an aromatic compound, e.g., salicylic acid, and a derivative thereof with high productivity using a microorganism. Provided are: a method for producing a microorganism having a modified sugar metabolic ...
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WO/2017/025766A1 |
The present invention relates to a recombinant microorganism useful for the production of L-methionine and process for the preparation of L-methionine. The microorganism of the invention is modified in a way that the L-methionine product...
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WO/2017/022944A1 |
The present invention relates to a method for producing a lysine carboxylase mutant, characteristics of the mutant, a gene coding the lysine decarboxylase mutant, and a method for producing cadaverine using the same. The present inventio...
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WO/2017/018060A1 |
The present invention provides a method for reacting a thiol compound represented by formula (I) (R in the formula is as defined in the description) with L-serine in the presence of cystathionine β-synthase to produce a cysteine derivat...
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WO/2017/016444A1 |
Provided in the present invention is a method for preparing an L-2-aminobutyric acid through biocatalysis, comprising the following steps: constructing a genetically engineered bacteria for simultaneously expressing an FDH and an LDH to ...
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WO/2017/014532A1 |
The present invention relates to a recombinant microorganism for producing putrescine or ornithine and a method for producing putrescine or ornithine by using the same.
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WO/2017/009047A1 |
The present invention relates to a method for producing L-methionine, in which O-acetyl-L- homoserine is reacted with methyl mercaptan or with a salt of methyl mercaptan, in the presence of a protein having O-acetylhomoserine sulphydryla...
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WO/2017/009009A1 |
The present invention relates to a method of producing at least one amino acid from a carbon source in aerobic conditions, the method comprising: (a)step of producing ethanol and/or acetate from the carbon source in aerobic conditions, c...
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WO/2017/011592A1 |
Methods, compositions, and cells for generating acyl alcohols. Compositions comprising acyl alcohols. Methods of cleaving acyl amino acids and/or acyl alcohols to generate free fatty acids, free amino acids, and/or free alcohols.
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WO/2017/007159A1 |
The present invention relates to a microorganism having L-lysine productivity and a method for producing L-lysine by using the same. More particularly, the present invention relates to: a Corynebacterium sp. microorganism having been mut...
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WO/2017/003721A1 |
The present invention is directed to processes for the preparation of lisdexamfetamine and related derivatives, wherein the processes comprise coupling to racemic or enantiomerically enriched amphetamine and wherein the resulting product...
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WO/2017/003104A1 |
The present invention relates to novel separated polypeptide, which has transaminase activity, polynucleotide, which codes same, a microorganism, which comprises the polynucleotide, and a method, for deamidating an amino compound, using ...
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WO/2016/209883A1 |
Provided herein are non-naturally occurring microbial organisms having biosynthetic pathways for production of target products and one or more genetic modifications that reduce a byproduct of the biosynthetic pathway. Compositions of tar...
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WO/2016/208831A1 |
The present invention relates to a method for preparing a lysophosphatidylethanolamine 18:1 by treating a phospholipid extracted from Pseudomonas sp. microorganisms with phospholipase A2. The lysophosphatidylethanolamine 18:1 of the pres...
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WO/2016/208854A1 |
The present invention relates to a recombinant microorganism for producing putrescine or ornithine and a method for producing putrescine or ornithine using the same. Specifically, the present invention relates to: a Corynebacterium sp. m...
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WO/2016/205939A1 |
Methods for making alkaloid compounds, including ephedrine and derivatives thereof. The methods involve the performance of an N-methyltransferase catalyzed chemical reaction.
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WO/2016/198529A1 |
The present invention relates to a recombinant nucleic acid molecule, a recombinant micro-organism, to a method for producing alanine and to the use of the recombinant nucleic acid molecule or the recombinant microorganism for the fermen...
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WO/2016/200614A2 |
Genetically engineered bacteria, pharmaceutical compositions thereof, and methods of modulating and treating disorders associated with hyperammonemia are disclosed.
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WO/2016/195439A1 |
The present disclosure relates to a protein capable of discharging O-acetyl-homoserine and a novel mutation thereof, a microorganism having an increased expression of the protein and the ability to produce an O-acetyl-homoserine, and a m...
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WO/2016/192694A1 |
The invention relates to a preparation method of (S)-l-(3-ethoxy-4-methoxyphenyl)- 2-(methylsulfonyl)-ethyl-amine (S)-l, or its N-acyl derivatives of general formula (S)-2. The amine (S)-l is the key intermediate in the synthesis of (S)-...
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WO/2016/191936A1 |
Disclosed is a preparation containing ergothioneine. The ergothioneine is provided by an extracellular ferment liquor and/or the concentration of the extracellular ferment liquor which is obtained by removing the mycelia from the ferment...
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WO/2016/193351A2 |
Recombinant microorganism for improved production of fine chemicals The present invention relates to a recombinant nucleic acid molecule, a recombinant micro- organism, to a method for producing alanine and to the use of the recombinant ...
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WO/2016/184656A1 |
The present invention provides a microbial cell capable of producing at least one alpha amino acid from at least oneshort chain fatty acid, wherein the cell is genetically modified to comprise - at least a first genetic mutation that inc...
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WO/2016/183413A1 |
The present disclosure provides compositions and methods for making and using methanotrophic proline auxotrophs.
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WO/2016/182322A1 |
The present invention relates to an Escherichia sp. microorganism having improved L-tryptophan productivity by inactivating the activity of a phosphatase. In addition, the present invention relates to a method for preparing L-tryptophan ...
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WO/2016/182321A1 |
The present invention relates to microorganisms of the genus Escherichia, which has an improved L-tryptophan producing ability by deactivating phosphatase activity. In addition, the present invention relates to a method for producing L-t...
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WO/2016/179296A1 |
Methods and engineered yeast cells for generating a benzylisoquinoline alkaloid product are provided herein. A method comprises providing engineered yeast cells and a feedstock to a reactor. In the reactor, the engineered yeast cells are...
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WO/2016/177620A1 |
There is provided a microbial cell for producing at least one acyl amino acid, wherein the cell is genetically modified to comprise: - a first genetic mutation that increases the expression relative to a wild type cell of at least one li...
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WO/2016/179545A1 |
The present disclosure provides compositions and methods for using modified hydrogenotrophic microorganisms capable of biologically utilizing or converting CO and/or CO2 gas, optionally in the presence of H2, into methionine.
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WO/2016/171538A1 |
The invention relates to a method for synthesising vanillylamides of organic acids, based on vanillin oxime, inorganic salts of vanillylamine or based on organic salts of vanillylamine having organic acids. The method involves: the chemi...
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WO/2016/166524A1 |
The present invention provides a modified collagen comprising S-nitroso groups and a method of manufacture of such a modified collagen. Also provided is a wound dressing comprising such a modified collagen, particularly a wound dressing ...
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WO/2016/166120A1 |
The present invention relates to a mutant transaminase with increased transaminase activity relative to the wild-type transaminase, a fusion protein comprising the transaminase, a polynucleotide coding for the transaminase, a host cell c...
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