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WO/2017/176277A1 |
The present invention describes an approach to produce taurine or increase hypotaurine or taurine production in prokaryotes or eukaryotes. More particularly, the invention relates to genetic transformation of organisms with algal, microa...
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WO/2017/169275A1 |
The present invention addresses the problem of providing a method for culturing a microorganism, whereby the microorganism can adapt to an inhibitor and thus fermentation inhibition can be sufficiently decreased, and a method for produci...
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WO/2017/167866A1 |
Described herein are recombinant microbial host cells comprising biosynthetic pathways and their use in producing oxidation products and downstream products, e.g., melatonin and related compounds, as well as enzyme variants, nucleic acid...
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WO/2017/167803A1 |
The present invention relates to a method for producing a polyacrylamide solution having increased viscosity. In particular, the present invention is related to the separation of a biocatalyst from an aqueous acrylamide solution prepared...
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WO/2017/160042A1 |
The present application relates to an L-histidine producing Corynebacterium glutamicum variant and a method for producing L-histidine, using the same.
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WO/2017/159976A1 |
The present application relates to a putrescine-producing microorganism in which the activity of formate dehydrogenase is activated, and a method for producing putrescine using the same.
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WO/2017/154955A1 |
The present invention is a glucose composition characterized by containing, as equivalents in an aqueous solution of said composition having a glucose concentration of 100 g/L, 0-25 g/L of xylose, 0.1-10 g/L of acetic acid, 0.15-2.0 g/L ...
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WO/2017/148357A1 |
The present invention relates to a sacubitril intermediate and a preparation method thereof. The sacubitril intermediate can be prepared by subjecting a compound to a deprotection reaction. The intermediate can be used as a raw material ...
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WO/2017/150560A1 |
Provided are a method for obtaining an HNL gene and HNL derived from a millipede other than Chamberlinius hualienensis, and preparing a practically useable amount of HNL; and a method for producing optically active cyanohydrin using this...
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WO/2017/151997A1 |
A method of making a polypeptide including one or more D-amino acids is provided that includes the use of elongation factor P with translational machinery.
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WO/2017/151573A1 |
Methods for the production of L-glufosinate (also known as phosphinothricin or (S)-2-amino-4-(hydroxy(methyl)phosphonoyl)butanoic acid) are provided. The methods comprise a two-step process. The first step involves the oxidative deaminat...
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WO/2017/146188A1 |
Provided is a method for producing a basic amino acid such as L-lysine. A basic amino acid or a fermentation product containing the same is produced by a method comprising: (A) a step for obtaining a fermentation liquid containing a basi...
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WO/2017/146195A1 |
The present invention provides a method for producing L-amino acids by fermentation using a bacterium belonging to the family Enterobacteriaceae which has been modified to overexpress a gene encoding an iron exporter, such as a fetB gene...
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WO/2017/146241A1 |
The present invention addresses the problem of providing a microorganism capable of efficiently producing para-aminobenzoic acid (4-ABA) or a salt thereof using a saccharide as the starting material, and a method for efficiently producin...
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WO/2017/143194A2 |
The present disclosure describes biocatalytic processes for producing a product, comprising providing an aqueous stream (AS) comprising at least one fermentable substrate and a gaseous stream (GS) comprising at least one of CO2 /H2, H2, ...
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WO/2017/137668A1 |
The invention relates to a method for the protein enrichment of a microalga cultivated under heterotrophic conditions, of the genus Chlorella, and more particularly Chlorella protothecoides, characterised in that it comprises: - a first ...
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WO/2017/133242A1 |
Provided is a method for extracting a 1,5-pentanediamine from a solution system containing a 1,5-pentanediamine salt. The method comprising adding to the solution system an insoluble basic substance to form a solution system containing a...
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WO/2017/136466A1 |
The present invention provides compositions and methods for catalyzing the formation of carbon-silicon bonds using heme proteins. In certain aspects, the present invention provides heme proteins, including variants and fragments thereof,...
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WO/2017/136344A1 |
This document describes biochemical pathways for producing pimeloyl-CoA using a polypeptide having the enzymatic activity of a hydroperoxide lyase to form non-3-enal and 9- oxononanoate from 9-hydroxyperoxyoctadec-10,12-dienoate. Non-3-e...
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WO/2017/130007A1 |
There is described a method for producing polymeric 3-hydroxypropionamide (3HP amide), the method comprising: culturing an Acetobacter lovaniensisbacterium in a growth medium containing phosphate and ammonium, wherein culturing of the ba...
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WO/2017/123692A1 |
The invention pertains to microorganisms resistant to nonvolatile side product from acid hydrolysate of lignocellulosic biomass. The acid hydrolysate resistant microorganism of the invention comprise genetic modifications to increase the...
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WO/2017/122189A1 |
The invention provides recombinant polynucleotides comprising a nucleic acid encoding a CYP76AD6 or related gene and their use for producing L-DOPA from tyrosine and treating dopamine-responsive disorders, such as Parkinson's Disease. Th...
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WO/2017/121863A1 |
The present invention relates to methods for the production of rhamnosylated flavonoids comprising the steps of contacting/incubating a glycosyl transferase with a flavonoid and obtaining a rhamnosylated flavonoid. In addition, the inven...
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WO/2017/122931A1 |
The present invention relates to a mutant microorganism for producing L-cysteine into which a gene encoding an L-cysteine metabolic pathway-related enzyme is introduced and, more particularly, to a mutant microorganism for producing an L...
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WO/2017/118871A1 |
The present invention relates to a method for the fermentative production of L- methionine and /or its derivatives comprising the step of i) culturing a microorganism optimised for the fermentative production of methionine in an appropri...
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WO/2017/109897A1 |
[Problem] To provide a method for producing a high-purity ether-type glycerophospholipid with high efficiency by a simple procedure. [Solution] This production method comprises treating a biological material or a tissue thereof with a pr...
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WO/2017/102853A1 |
The present invention relates to the production of o-aminobenzoic acid from fermentable substrates using yeast cells.
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WO/2017/103163A1 |
The present invention provides an improved membrane based process to separate amines or organic acids from a solution comprising at least one amine or at least one organic acid, respectively, according to their hydrophobic properties. In...
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WO/2017/097828A1 |
Provided are bacterial cells genetically modified to improve their tolerance to certain commodity chemicals, such as polyamines, and methods of preparing and using such bacterial cells for production of polyamines and other compounds.
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WO/2017/093254A1 |
The invention relates to a method of preparing engineered target polypeptides (TP) comprising in its amino acid sequence one or more, identical or different, non-canonical amino acid (ncAA) residues, by expressing said TP in an insect ce...
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WO/2017/096310A1 |
This document describes biochemical pathways for producing 7-aminoheptanoic acid using a β-ketoacyl synthase or a β-ketothiolase to form either a 5-amino-3-oxopentanoyl-[ACP] or 5-amino-3-oxopentanoyl-CoA intermediate. 7-aminoheptanoic...
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WO/2017/096260A1 |
This document describes biochemical pathways for producing 7-aminoheptanoic acid using a β-ketoacyl synthase or a β-keioihiolase to form an N-acetyl-5-amino-3- oxopentanoyl-CoA intermediate. 7-aminoheptanoic acid can be enzymatieally c...
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WO/2017/089077A1 |
The present invention relates to a method for producing L-methionine in which a microorganism is cultured in the presence of L-homoserine and methyl mercaptan, a salt of the same or dimethyl disulfide whereby the L-methionine is accumula...
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WO/2017/088094A1 |
Provided is a codon-optimized β- mannase signal peptide(MSP), and a nucleotide sequence thereof is shown as SEQ ID NO:1, and a genetically engineered bacteria comprising the signal peptide and the β- mannase, and a method for manufactu...
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WO/2017/089408A1 |
The present invention relates to an enzymatic method for producing deconjugated bile acids from bile.
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WO/2017/088095A1 |
The present invention provides a signal peptide and application thereof in synthesis of L-arginine from conjac powder and value enhancement of conjac powder. The signal peptide has a nucleotide sequence of SEQ ID NO: 1. The signal peptid...
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WO/2017/085241A1 |
The present invention provides a genetically modified microbial cell for production of lysine, comprising a transgene encoding a polypeptide capable of exporting lysine from the cell. The genetically modified microbial cell for productio...
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WO/2017/085170A1 |
The invention relates to a method for producing aminobenzoic acid or a aminobenzoic acid derivative via the fermentation of a suitable raw material under the influence of suitable microorganisms and obtaining a fermentation broth contain...
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WO/2017/082144A1 |
The present invention provides a compound represented by formula (I), or a pharmaceutically acceptable salt or prodrug thereof. The present invention also provides: a composition which includes the compound represented by formula (I), or...
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WO/2017/082827A1 |
A non-saccharide glycosaminoglycan mimetic molecule comprising a polyproline backbone and one or more non- saccharide molecules, wherein the non-saccharide molecules are bound to one or more prolines and/or proline derivatives on the pol...
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WO/2017/082374A1 |
The present invention provides a method for producing Nε-dodecanoyl-L-lysine, said method using an enzyme that performs appropriately for the industrial production of Nε-dodecanoyl-L-lysine. Specifically, the present invention provides...
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WO/2017/080111A1 |
Provided is a genetically-engineered strain for producing cadaverine. A lysine decarboxylase promoter 1dcCp is replaced as an environmental/nutritional factor-control promoter, and a signal peptide is expressed at the same time; the lysi...
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WO/2017/079872A1 |
Provided are microorganisms genetically modified to overexpress porin polypeptides to enhance the production of lysine and lysine derivatives by the microorganism. Also provided are methods of generating such microorganism, and methods o...
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WO/2017/083493A1 |
This document describes biochemical pathways for biosynthesizing a 3-oxo-7-hydroxyheptanoyl-CoA intermediate using a β-ketothiolase, and enzymatically converting 3-oxo-7-hydroxyheptanoyl-CoA to 7-hydroxyheptanoic acid. - 7-hydroxyheptan...
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WO/2017/074065A1 |
The present invention relates to a method for producing a heavy chain diamine and, more specifically, to a method for producing a heavy chain diamine from an alcohol or alkane derived from a fatty acid, by culturing a recombinant microor...
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WO/2017/074063A1 |
The present invention relates to a method for producing a heavy chain aminocarboxylic acid and, more particularly, to a recombinant microorganism in which a fatty aldehyde dehydrogenase gene in ω-oxidative metabolic pathway and a β-oxi...
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WO/2017/071006A1 |
Provided is a Corynebacterium crenatum for recombinant expression of an arginine deiminase, wherein same is a genetically engineered bacterium obtained by means of arginine deiminase genes from Lactobacillus brevis and being connected to...
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WO/2017/069578A1 |
The present application relates to a Corynebacterium sp. microorganism having an L-isoleucine producing ability and containing a protein having citramalate synthase activity, and a method for producing L-isoleucine by using the same.
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WO/2017/065529A1 |
The present application relates to a novel O-acetylhomoserine sulfhydrylase variant, a polynucleotide coating same, a vector comprising the polynucleotide, a strain capable of expressing the variant, and a method for producing L-methioni...
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WO/2017/065567A1 |
The present disclosure relates to bio-based N-acetyl-L-methionine and a preparation method thereof. Additionally, the present disclosure relates to a feed additive containing the N-acetyl-L-methionine, a feed composition containing the f...
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