| Document |
Document Title |
|
WO/2007/124898A1 |
This invention is directed to compounds of formula (I): to pharmaceutical compositions comprising them; to combination products comprising them; and to their use in therapy.
|
|
WO/2007/122847A1 |
A reagent for organic syntheses with which a chemical reaction can be conducted in a liquid phase and unnecessary compound(s) can be easily separated at low cost from the liquid phase after completion of the reaction. The reagent for org...
|
|
WO/2007/119042A2 |
The present invention relates to a process for the treatment of a product stream, more specifically of a product stream from an autothermal cracking process, said product stream comprising one or more olefins, hydrogen, carbon monoxide, ...
|
|
WO/2007/107352A1 |
The present invention provides novel compounds that inhibit cell proliferation, in particular through the disruption of chromosome segregation and uses of these compounds for treating, ameliorating or preventing diseases, conditions or d...
|
|
WO/2007/105793A1 |
Disclosed is a method for commercially advantageously producing an N-nitroisourea, which is useful as a synthetic intermediate for pharmaceutical products and agricultural chemicals, or a salt of such an N-nitroisourea. Specifically disc...
|
|
WO/2007/106525A1 |
Compounds of the formula (I); wherein R1 is a member selected from the group consisting of C1-C8alkyl, arylC0-C8alkyl, C3-C12cycloalkyl and heterocyclyl, Y1 is selected from the group consisting of a bond, C(R5)2, NR5 and O; Y2 is select...
|
|
WO/2007/105050A1 |
Dibenzyl amine compounds and derivatives, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain oth...
|
|
WO/2007/103485A2 |
The present invention relates to methods, kits, and compositions for purifying small RNA molecules. In particular, the present invention provides methods for purifying small RNA molecules from a sample containing both small RNA molecules...
|
|
WO/2007/093211A1 |
The invention relates to a process for the treatment of an aqueous mixture comprising a dipolar aprotic compound, comprising: a) an adsorption step, in which the aqueous mixture is brought into contact with a porous adsorbent, whereby th...
|
|
WO/2007/091390A1 |
Disclosed is an improved method for producing a nitroisourea derivative which is necessary for producing a nitroguanidine derivative having an insecticidal activity. Specifically disclosed is a method for producing a nitroisourea derivat...
|
|
WO2004007437A9 |
The invention relates to urea-substituted and urethane-substituted acylureas, to physiologically compatible salts thereof and to their physiologically functional derivatives. The invention thus relates to compounds of formula (I), wherei...
|
|
WO/2007/091392A1 |
Disclosed is an industrially advantageous process for production of O-methyl-N-nitroisourea. O-methyl-N-nitroisourea of the formula (1) or a salt thereof can be produced in a high yield by performing the nitration of O-methylisourea of t...
|
|
WO/2007/084882A2 |
Disclosed is an improved multi-step process for preparing a compound of Formula I and intermediates used therein: (I) wherein R1 to R3 are as defined herein. The compounds of formula I inhibit the binding of human intercellular adhesion ...
|
|
WO/2007/080109A1 |
The present invention relates to novel substituted benzyloxy-phenylmethylurea derivatives, processes for their preparation, and their use in medicaments, especially for the prophylaxis and treatment of diseases associated with Cold Menth...
|
|
WO/2007/079930A1 |
The present invention relates to substituted cyclohexylmethyl derivatives, to processes for preparing them, to pharmaceuticals comprising these compounds, and to the use of substituted cyclohexylmethyl derivatives for producing pharmaceu...
|
|
WO/2007/068394A2 |
The invention relates to novel specifically trifluoromethyl and halogen substituted 1 ,3- diphenyl ureas and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects l...
|
|
WO/2007/068395A1 |
The invention relates to novel specifically trifluoromethyl and halogen substituted 1,3-diphenyl ureas and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects lik...
|
|
WO/2007/068330A1 |
The present invention relates to 2-adamantylurea derivatives of formula (I) as selective inhibitors of the enzyme 11-beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) and the use of such compounds for the treatment and prevention of m...
|
|
WO/2007/066496A1 |
The present invention relates to a benzoylurea compound represented by the formula (1): wherein R2 represents a lower alkylene group etc., and A represents a group represented by OR3, S(O) nR4 or NR5R6, or a salt thereof, and use of the ...
|
|
WO/2007/064273A1 |
The present invention relates to compounds of formula (I) and processes for preparing such compounds, their use in the treatment of obesity, psychiatric and neurological disorders, to methods for their therapeutic use and to pharmaceutic...
|
|
WO/2007/062308A2 |
Compounds of formula (Ia) and (Ib) wherein A, B, C and R1 are described herein. The compounds (Ia) and (Ib) are useful as CETP inhibitors.
|
|
WO2007002635B1 |
The present invention provides novel C-linked cyclic compounds and analogues of Formula (I): or a stereoisomer, tautomer, pharmaceutically acceptable salt or solvate form thereof, wherein the variables A, B, D and W are as defined herein...
|
|
WO/2007/056469A2 |
Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.
|
|
WO/2007/048771A1 |
A compound of formula (I), wherein substituents are as given above, useful in the treatment of a disease mediated by the action of CCR3, in particular inflammatory or obstructive airway diseases.
|
|
WO/2007/049656A1 |
Disclosed are a novel fluoroadamantane derivative and a method for producing the same. Specifically disclosed are a method for producing a compound (2) shown below wherein a compound (1) shown below is reacted with an azide and then subj...
|
|
WO/2007/049158A2 |
The invention relates to novel biaromatic derivatives, which are modulators of peroxisome proliferator-activated receptors, known as PPAR, of formula (I). The invention also relates to the process for preparing them and to their use in p...
|
|
WO/2007/048557A1 |
Compounds of the formula (I), wherein R1, R2, X and N are as defined in the specification; L is F, NH2, NHAlk or N(Alk)2 n is 1 or 2; A' and A" are terminal groups as defined in the specification. The compounds have utility as HIV-1 prot...
|
|
WO/2007/046513A2 |
The present invention relates to a benzoylurea compound represented by formula (I), wherein X and Y represent a fluorine atom or a chlorine atom, R1 represents a lower alkyl group or the like, R2 represents a lower alkyl group, R3 repres...
|
|
WO/2007/036572A1 |
The invention relates to compounds of formula (I) which contain aldimine, and to the use thereof. Said compounds which contain aldimines are characterised in that they are odour-less and during hydrolysis the odour-free aldehydes are sep...
|
|
WO/2007/029155A2 |
The present invention relates to an improved process for preparing pure celiprolol base in monohydrate form by crystallizing crude celiprolol base in one or more carboxylic acid ester solvents and its conversion to pharmaceutically accep...
|
|
WO/2007/013811A2 |
The present invention in a first aspect relates to flavour modulation in foodstuffs, beverages, tobacco products and oral care products, using a flavour modulating substance selected from the group represented by formula (I), edible salt...
|
|
WO/2007/006761A1 |
This invention relates to dicycloalkylcarbamoyl ureas of formula (I), which are activators of glucokinase and thus may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activ...
|
|
WO/2007/002639A2 |
The present disclosure provides amide-based, non-nucleoside compounds having antiviral activity against Hepacivirus, such as hepatitis C virus (HCV) , methods and intermediates for synthesizing such compounds, and methods of using the co...
|
|
WO/2006/135910A1 |
The invention describes novel crosslinking compounds that include photoactivatable moieties. Several families of compounds are disclosed that can include one or more hydrophilic moieties that help to solubilize the compounds in aqueous e...
|
|
WO/2006/133588A1 |
It has been found that phenylurea compounds, in particular diphenylurea compounds of the formula (I), and pharmaceutically acceptable salts thereof are medicaments for the treatment of neurodegenerative diseases, in particular diseases i...
|
|
WO/2006/135694A2 |
Disclosed herein are novel aromatic-containing compounds and methods for using various aromatic-containing compounds for treatment and prevention of diseases and disorders related to the Urotensin II receptor.
|
|
WO/2006/131381A1 |
The invention relates to a method for producing N-aryl carbamates (urethanes) and N-aryl isocyanates. According to said method, aromatic nitro compounds are subjected to a reductive carbonylation in the presence of carbon dioxide and org...
|
|
WO/2006/128670A1 |
The present invention is related to a compound, preferably a C5a receptor antagonist, having the following structure, Rl, R2, R3, R4, R5, R6, R7, R8, R9, Rl0, RI l, R12, R13, R14, R15, R16, Rl7, R18, Rl9, R20, R21 and R22 are individuall...
|
|
WO/2006/128268A1 |
The present invention describes functionalizeds derivatives of ethyl 6-N- alkyl and/or 6-N-aryl ureas [1 ,3]dioxolo[5,4-g]quinolin-7-carboxylate (3a-z, 4a-z) and similar types (5a-z), of general formula (I, II, III and IV), useful in the...
|
|
WO/2006/126635A1 |
A compound represented by the general formula below or a salt thereof is a useful intermediate in the production of a [2-(3,3,5,5-tetramethylcyclohexyl)phenyl]piperazine compound that has excellent cell adhesion inhibitory effect and cel...
|
|
WO/2006/122788A1 |
The present invention provides a compound of formula (I) wherein: R1 is a group selected from -CH2OH, -NHC(O)H and R2 is a hydrogen atom; or R1 together with R2 form the group -NH-C(O)-CH=CH- wherein the nitrogen atom is bound to the car...
|
|
WO/2006/122782A1 |
N-(2-hydroxyalkanoyl) -N, N' -dialkylureas of general formula (I) are described A-X-(A)n, where A: m = 0 or m = 1; when m = 0, X = R''', where R''' is an aliphatic, cycloaliphatic, arylaliphatic radical, C1-C18; when m = 1, X = -(CH2)n-,...
|
|
WO/2006/122772A1 |
The invention relates to salts of substituted allophanates, to methods for producing them, to drugs containing said compounds and to the use of said compounds for producing drugs.
|
|
WO/2006/122072A2 |
The present invention relates to processes for preparing biaryl ureas derivatives and analogs thereof. The invention also provides compounds useful as intermediates in the processes of the present invention. The process is useful for pre...
|
|
WO/2006/117549A1 |
Compounds of formula (I) are inhibitors of histone deacetylase activity, and are useful in the treatment of, for example, cancers, wherein R1 is a carboxylic acid group (-COOH), or an ester group which is hydrolysable by one or more intr...
|
|
WO/2006/118071A1 |
In an apparatus for synthesizing urea and a method of improving the same, it becomes possible to provide a heavy condenser at a relatively low position and, further, it becomes possible to overcome the problems caused by passing a proces...
|
|
WO/2006/118070A1 |
In an apparatus for synthesizing urea, it is avoided to pass downward a urea synthesis solution, which is a two-phase gas-liquid stream, and the stream is stabilized as such (i.e., as being the two-phase gas-liquid stream) to enable smoo...
|
|
WO/2006/108712A1 |
The invention relates to poly-substituted tetrahydronaphtalene derivatives of formula (I) and to a method for the production and the use thereof in the form of antiphlogistics.
|
|
WO/2006/101318A1 |
This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receotor 1; VR1; TRPV1 )antagonist; and a pharmaceutical composition containing the same. The...
|
|
WO/2006/101321A1 |
This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receotor 1; VR1; TRPV1) antagonist; and a pharmaceutical composition containing the same. The...
|
