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Matches 451 - 500 out of 6,182

Document Document Title
WO/2007/093211A1
The invention relates to a process for the treatment of an aqueous mixture comprising a dipolar aprotic compound, comprising: a) an adsorption step, in which the aqueous mixture is brought into contact with a porous adsorbent, whereby th...  
WO/2007/091390A1
Disclosed is an improved method for producing a nitroisourea derivative which is necessary for producing a nitroguanidine derivative having an insecticidal activity. Specifically disclosed is a method for producing a nitroisourea derivat...  
WO2006084688A8
Compounds of the formula (I): Wherein R1, R2, X and N are as defined in the specification; E is N, CH; A1 and A" are terminal groups as defined in the specification. The compounds have utility as HIV-I protease inhibitors.  
WO/2007/046513A3
The present invention relates to a benzoylurea compound represented by formula (I), wherein X and Y represent a fluorine atom or a chlorine atom, R1 represents a lower alkyl group or the like, R2 represents a lower alkyl group, R3 repres...  
WO2004007437A9
The invention relates to urea-substituted and urethane-substituted acylureas, to physiologically compatible salts thereof and to their physiologically functional derivatives. The invention thus relates to compounds of formula (I), wherei...  
WO/2007/091392A1
Disclosed is an industrially advantageous process for production of O-methyl-N-nitroisourea. O-methyl-N-nitroisourea of the formula (1) or a salt thereof can be produced in a high yield by performing the nitration of O-methylisourea of t...  
WO/2007/068394A3
The invention relates to novel specifically trifluoromethyl and halogen substituted 1 ,3- diphenyl ureas and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects l...  
WO/2007/084882A2
Disclosed is an improved multi-step process for preparing a compound of Formula I and intermediates used therein: (I) wherein R1 to R3 are as defined herein. The compounds of formula I inhibit the binding of human intercellular adhesion ...  
WO/2007/080109A1
The present invention relates to novel substituted benzyloxy-phenylmethylurea derivatives, processes for their preparation, and their use in medicaments, especially for the prophylaxis and treatment of diseases associated with Cold Menth...  
WO/2007/079930A1
The present invention relates to substituted cyclohexylmethyl derivatives, to processes for preparing them, to pharmaceuticals comprising these compounds, and to the use of substituted cyclohexylmethyl derivatives for producing pharmaceu...  
WO/2007/019308A3
Acylfulvene analogs, which inhibit tumor growth, especially solid tumor growth, and which have an adequate therapeutic index to be effective for in vivo treatment are provided herein. The compounds described herein are useful as anti-neo...  
WO/2007/002639A3
The present disclosure provides amide-based, non-nucleoside compounds having antiviral activity against Hepacivirus, such as hepatitis C virus (HCV) , methods and intermediates for synthesizing such compounds, and methods of using the co...  
WO/2007/068394A2
The invention relates to novel specifically trifluoromethyl and halogen substituted 1 ,3- diphenyl ureas and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects l...  
WO/2007/068395A1
The invention relates to novel specifically trifluoromethyl and halogen substituted 1,3-diphenyl ureas and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects lik...  
WO/2007/068330A1
The present invention relates to 2-adamantylurea derivatives of formula (I) as selective inhibitors of the enzyme 11-beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) and the use of such compounds for the treatment and prevention of m...  
WO/2007/066496A1
The present invention relates to a benzoylurea compound represented by the formula (1): wherein R2 represents a lower alkylene group etc., and A represents a group represented by OR3, S(O) nR4 or NR5R6, or a salt thereof, and use of the ...  
WO/2007/064273A1
The present invention relates to compounds of formula (I) and processes for preparing such compounds, their use in the treatment of obesity, psychiatric and neurological disorders, to methods for their therapeutic use and to pharmaceutic...  
WO/2007/062308A2
Compounds of formula (Ia) and (Ib) wherein A, B, C and R1 are described herein. The compounds (Ia) and (Ib) are useful as CETP inhibitors.  
WO2007002635B1
The present invention provides novel C-linked cyclic compounds and analogues of Formula (I): or a stereoisomer, tautomer, pharmaceutically acceptable salt or solvate form thereof, wherein the variables A, B, D and W are as defined herein...  
WO/2007/056469A2
Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.  
WO/2007/013811A3
The present invention in a first aspect relates to flavour modulation in foodstuffs, beverages, tobacco products and oral care products, using a flavour modulating substance selected from the group represented by formula (I), edible salt...  
WO/2007/048771A1
A compound of formula (I), wherein substituents are as given above, useful in the treatment of a disease mediated by the action of CCR3, in particular inflammatory or obstructive airway diseases.  
WO/2006/122072A3
The present invention relates to processes for preparing biaryl ureas derivatives and analogs thereof. The invention also provides compounds useful as intermediates in the processes of the present invention. The process is useful for pre...  
WO/2007/049656A1
Disclosed are a novel fluoroadamantane derivative and a method for producing the same. Specifically disclosed are a method for producing a compound (2) shown below wherein a compound (1) shown below is reacted with an azide and then subj...  
WO/2007/049158A2
The invention relates to novel biaromatic derivatives, which are modulators of peroxisome proliferator-activated receptors, known as PPAR, of formula (I). The invention also relates to the process for preparing them and to their use in p...  
WO/2007/048557A1
Compounds of the formula (I), wherein R1, R2, X and N are as defined in the specification; L is F, NH2, NHAlk or N(Alk)2 n is 1 or 2; A' and A" are terminal groups as defined in the specification. The compounds have utility as HIV-1 prot...  
WO2006128268A8
The present invention describes functionalizeds derivatives of ethyl 6-N- alkyl and/or 6-N-aryl ureas [1 ,3]dioxolo[5,4-g]quinolin-7-carboxylate (3a-z, 4a-z) and similar types (5a-z), of general formula (I, II, III and IV), useful in the...  
WO/2007/046513A2
The present invention relates to a benzoylurea compound represented by formula (I), wherein X and Y represent a fluorine atom or a chlorine atom, R1 represents a lower alkyl group or the like, R2 represents a lower alkyl group, R3 repres...  
WO/2007/036572A1
The invention relates to compounds of formula (I) which contain aldimine, and to the use thereof. Said compounds which contain aldimines are characterised in that they are odour-less and during hydrolysis the odour-free aldehydes are sep...  
WO/2007/002635A3
The present invention provides novel C-linked cyclic compounds and analogues of Formula (I): or a stereoisomer, tautomer, pharmaceutically acceptable salt or solvate form thereof, wherein the variables A, B, D and W are as defined herein...  
WO/2006/060774A3
The present invention provides compounds with activity against a variety of flaviviruses, uses thereof, and methods for identifying such compounds.  
WO/2006/052542A3
CB1 antagonists are provided. Such compounds may be used to modulate CB1 activity in vivo or in vitro, and are particularly useful in the treatment of conditions responsive to CB1 receptor modulation in humans, domesticated companion ani...  
WO/2007/029155A2
The present invention relates to an improved process for preparing pure celiprolol base in monohydrate form by crystallizing crude celiprolol base in one or more carboxylic acid ester solvents and its conversion to pharmaceutically accep...  
WO/2006/135694A3
Disclosed herein are novel aromatic-containing compounds and methods for using various aromatic-containing compounds for treatment and prevention of diseases and disorders related to the Urotensin II receptor.  
WO/2006/119713A3
The invention relates to chemical compounds which are obtained by means of in silico molecular modelling and which have a structure that can be used to block phosphorylation by interacting said compounds with the phosphorylation domain o...  
WO/2005/122379A3
The present invention provides a 4ß1 integrin ligands that display high binding affinity, specificity, and stability. The ligands comprise a peptide having n independently selected amino acids, wherein at least one amino acid is an unna...  
WO/2007/013811A2
The present invention in a first aspect relates to flavour modulation in foodstuffs, beverages, tobacco products and oral care products, using a flavour modulating substance selected from the group represented by formula (I), edible salt...  
WO/2007/006761A1
This invention relates to dicycloalkylcarbamoyl ureas of formula (I), which are activators of glucokinase and thus may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activ...  
WO/2007/002635A2
The present invention provides novel C-linked cyclic compounds and analogues of Formula (I): or a stereoisomer, tautomer, pharmaceutically acceptable salt or solvate form thereof, wherein the variables A, B, D and W are as defined herein...  
WO/2005/015158A3
The invention relates to compounds that specifically bind a T1R1/T1R3 or T1R2/T1R3 receptor or fragments or subunits thereof. The present invention also relates to the use of hetero-oligomeric and chimeric taste receptors comprising T1R1...  
WO/2007/002639A2
The present disclosure provides amide-based, non-nucleoside compounds having antiviral activity against Hepacivirus, such as hepatitis C virus (HCV) , methods and intermediates for synthesizing such compounds, and methods of using the co...  
WO2006020358A3
The invention is directed to certain biphenyl compounds. Specifically, the invention is directed to compounds according to Formula (I): wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, and Y are as defined below, and to pharmaceutically-accep...  
WO/2006/135910A1
The invention describes novel crosslinking compounds that include photoactivatable moieties. Several families of compounds are disclosed that can include one or more hydrophilic moieties that help to solubilize the compounds in aqueous e...  
WO/2006/133588A1
It has been found that phenylurea compounds, in particular diphenylurea compounds of the formula (I), and pharmaceutically acceptable salts thereof are medicaments for the treatment of neurodegenerative diseases, in particular diseases i...  
WO/2006/135694A2
Disclosed herein are novel aromatic-containing compounds and methods for using various aromatic-containing compounds for treatment and prevention of diseases and disorders related to the Urotensin II receptor.  
WO/2006/131381A1
The invention relates to a method for producing N-aryl carbamates (urethanes) and N-aryl isocyanates. According to said method, aromatic nitro compounds are subjected to a reductive carbonylation in the presence of carbon dioxide and org...  
WO/2006/128670A1
The present invention is related to a compound, preferably a C5a receptor antagonist, having the following structure, Rl, R2, R3, R4, R5, R6, R7, R8, R9, Rl0, RI l, R12, R13, R14, R15, R16, Rl7, R18, Rl9, R20, R21 and R22 are individuall...  
WO/2006/128268A1
The present invention describes functionalizeds derivatives of ethyl 6-N- alkyl and/or 6-N-aryl ureas [1 ,3]dioxolo[5,4-g]quinolin-7-carboxylate (3a-z, 4a-z) and similar types (5a-z), of general formula (I, II, III and IV), useful in the...  
WO/2006/126635A1
A compound represented by the general formula below or a salt thereof is a useful intermediate in the production of a [2-(3,3,5,5-tetramethylcyclohexyl)phenyl]piperazine compound that has excellent cell adhesion inhibitory effect and cel...  
WO/2006/122788A1
The present invention provides a compound of formula (I) wherein: R1 is a group selected from -CH2OH, -NHC(O)H and R2 is a hydrogen atom; or R1 together with R2 form the group -NH-C(O)-CH=CH- wherein the nitrogen atom is bound to the car...  

Matches 451 - 500 out of 6,182