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Patent Searching and Data


Matches 201 - 250 out of 6,127

Document Document Title
WO/2013/030358A1
The invention relates to 4-aminonaphthalene-2-carboxylic acids and 1-amino- isoquinoline-3-carboxylic acids as well as their pharmaceutically acceptable salts. The invention further relates to a process for the preparation of such compou...  
WO/2013/017714A1
The present invention relates to a family of new compounds of general formula (I) that act as low-molecular-weight organogels for a wide variety of solvents and that provide a gel that is very stable at high temperatures. General formula...  
WO/2012/165398A1
The present invention relates to a compound having an excellent DGAT inhibitory activity and an anti-feeding activity or a pharmacologically acceptable salt thereof. A compound represented by general formula (I) [wherein R represents a p...  
WO/2012/159557A1
The present invention relates to a substituted triazine phenylurea derivative and a use thereof as an inhibitor of protein kinases, especially Raf-1, and the compound of the present invention is useful in treatment of various disorders a...  
WO/2012/138706A1
Compounds and compositions comprising epoxyeicosatrienoic acid (EET) analogs that act as EET agonists and are useful as medications in the treatment of drug-induced nephrotoxicity, hypertension and other related conditions. Methods of ma...  
WO/2012/134943A1
Disclosed herein are compounds of formula (I) or pharmaceutically acceptable salts, solvates, or combinations thereof, (I) wherein X1, X2, X3, X4, J, K, L, X5, X6, Rb, G2, and m are defined in the specification. Compositions comprising s...  
WO/2012/121394A1
The present invention provides a substituted aromatic compound represented by general formula (I) [wherein A1, A2 and A3 independently represent an aryl group substituted by a hydrophilic group].  
WO/2012/081885A3
The present invention relates to compounds 1, 1a (S-enantiomer) and 1b (R-enantiomer) of the following formula 1, and a method for preparing the same. [formula 1] The novel compound of the formula 1 is used as an important intermediate f...  
WO/2012/117099A1
The present invention relates to a process for preparing polyisocyanates containing biuret groups from di- or polyisocyanates with diamines.  
WO/2012/108478A1
The present invention is a compound represented by formula (I) (in the formula, each of the reference numerals is as recited in the specification) or a salt thereof.  
WO/2012/100532A1
A modified 1,6-hexamethylene diisocyanate biuret curing agent and a preparation method therefor. The 1,6-hexamethylene diisocyanate biuret curing agent is formed by reacting a diol, water, and 1,6-hexamethylene diisocyanate in an organic...  
WO/2012/089137A1
Disclosed in the present invention is an arylurea compound represented by formula I, or a pharmaceutically acceptable salt, a polymorph, a solvate or a stereoisomer thereof, and an intermediate and use thereof. The arylurea compound I of...  
WO/2012/088776A1
Preparation methods of 2-(N-substituted)-amino-benzimidazole derivatives are disclosed, compring such steps: (1) reacting 2-(N-protecting group)-benzene-1,2-diamines with N- phenoxycarbonylamines to obtain 2-(N-substituted)-amino-aryl ur...  
WO/2012/081885A2
The present invention relates to compounds 1, 1a (S-enantiomer) and 1b (R-enantiomer) of the following formula 1, and a method for preparing the same. [formula 1] The novel compound of the formula 1 is used as an important intermediate f...  
WO/2012/069605A1
The present invention relates to a novel class of E,E-diene compounds and their use as a medicament, preferably as a dermatologic agent, and as a cosmetic. These novel compounds are particularly useful in treating and/or preventing infla...  
WO/2012/064417A1
The present invention comprises a compound of a compound of Formula 1 wherein Rf is a C2 to C-12 perfluoroalkyl optionally interrupted by one to four moieties each independently selected from the group consisting of -CH2-, -O-, -S-, -S(O...  
WO/2012/056014A1
Compounds of the formula (I) or salts thereof, wherein R1 represents alkyl, aryl, alkyl-aryl or aryl-alkyl, compositions containing same, and their use in counteracting human axillary malodour.  
WO/2011/159137A3
The present invention relates to a novel thiourea or urea derivative, a preparation method thereof, and a pharmaceutical composition for preventing or treating AIDS, containing the same as an active ingredient. According to the present i...  
WO/2012/054996A1
The present invention relates to functionalized aryl and/or heteroaryl urea compounds of general formula (I) and (II), and also salts and/or solvates and polymorphs thereof which can inhibit protein kinases from the MAPK family and also ...  
WO/2012/050041A1
The present invention provides a pest control agent, an acaricide, or a bactericide that contains, as the active ingredient thereof, at least one type of compound selected from aryloxyurea compounds represented by formula (V) (wherein R1...  
WO/2012/050482A1
Carbamide is produced at a high temperature and pressure in a plant which comprises a high pressure section including a reactor, a stripper, a condenser and a scrubber. Ammonia and carbon dioxide are reacted in the reactor to form a reac...  
WO/2012/028676A1
The invention relates to new compounds of the formula (I) to their use as medicaments, to methods for their therapeutic use and to pharmaceutical compositions containing them.  
WO/2011/122917A3
The present invention relates to an octahydrobinaphthol derivative which recognizes an amino acid and amino alcohol in a chiral-selective manner, converts L-amino acid into D-amino acid, and performs optical resolution on an amino acid a...  
WO/2012/004549A1
A compound of formula I-0, and its pharmaceutically acceptable salt or salts and physiologically hydrolysable derivatives in free form or salt form: wherein Z1 is C1-C4 linear or branched alkyl or alkenyl; R4 is selected from unsubstitut...  
WO/2011/157612A2
The invention relates to novel compounds derived from amino acids of formula (I) and also to cosmetic or dermatological compositions containing them and to their use as agents for treating human perspiration in a cosmetic composition. Th...  
WO/2011/159137A2
The present invention relates to a novel thiourea or urea derivative, a preparation method thereof, and a pharmaceutical composition for preventing or treating AIDS, containing the same as an active ingredient. According to the present i...  
WO/2011/157611A2
The invention relates to novel compounds derived from amino acids of formula (I) and also to cosmetic or dermatological compositions containing them and to their use as agents for treating human perspiration in a cosmetic composition. Th...  
WO/2011/140680A1
The present invention discloses compounds of formula (I), isomers, pharmaceutical salts or solvates thereof. The present invention also discloses a composition comprising the compounds of formula (I), isomers, pharmaceutical salts or sol...  
WO/2011/140832A1
The present invention discloses a compound of general formula (I), or isomer, pharmaceutically acceptable salt and solvate thereof, as well as composition, medicinal use, and preparative method thereof. Said composition further comprises...  
WO/2011/076784A3
The present invention relates to a compound of formula (I): Formula (I), wherein: - n is 0, 1 or 2; - A is in particular CH or N; - X is in particular CO, SO2, CS, and R1 is in particular H, - R2 is a group of formula NR3R4 or OR5, R3 an...  
WO/2011/064556A3
There is provided a mixture having a freezing point of up to 100°C formed by a process comprising the step of contacting: (A) from 1 to 2 equivalents of a compound of formula (I) AIX3 (I) wherein each X independently represents Cl, Br o...  
WO/2011/136231A1
Disclosed is a process for producing a high-purity bisaminophenylalkylurea as the desired compound in high yield while attaining a high volumetric efficiency and generating little by-product. A (nitrophenyl)alkylamine hydrohalogenide rep...  
WO/2011/131576A1
Tranylcypromine derivatives useful as therapeutic agents, particularly for the prevention and/or treatment of diseases and conditions associated with the activity of histone demethylases LSD1 and LSD2, such as the diseases characterized ...  
WO/2011/122917A2
The present invention relates to an octahydrobinaphthol derivative which recognizes an amino acid and amino alcohol in a chiral-selective manner, converts L-amino acid into D-amino acid, and performs optical resolution on an amino acid a...  
WO/2010/149760A3
The present invention concerns prodrugs of mexiletine (and mexiletine's active metabolite) with amino acids or peptides and pharmaceutical compositions containing such prodrugs. Methods for providing pain relief, treating arrhythmia, dec...  
WO/2011/113368A1
A fluoro-substituted deuterated diphenylurea compound, especially 4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluoro phenoxy)- 2-(N-1',1',1'-d3-methyl)picolinamide, preparing method and use for treating or preventing tumor and ...  
WO/2011/113367A1
Methods and processes for preparation and production of deuterated ω-diphenylure are disclosed. Especially, a kind of deuterated ω-diphenylurea compounds which can inhibit phosphokinase and the preparation method of N-(4-chloro-3-(trif...  
WO/2011/108690A1
The disclosed composition containing a compound represented by general formula (I) (refer to the Description for the definitions of the symbols used in the formula), or a salt thereof, has excellent CaSR agonist effects and provides phar...  
WO/2011/108724A1
An object is to provide a CaSR agonist agent that has excellent CaSR agonist effects, and particularly, a pharmaceutical product that can prevent or remedy diabetes or obesity by the effect of CaSR activation. The aforementioned object i...  
WO/2011/018170A3
The object of the present invention is to provide novel carboxamides which exhibit an excellent pesticidal activity as pesticides. Disclosed are the carboxamides represented by the following Formula (I) wherein each substituent is as def...  
WO/2011/084106A1
Disclosed herein is a compound of structure (A): In this compound, X is either O or S, R1 is a rigid group, R2 is a hydrophilic group such that (A) is capable of self-assembly in water, and R3 is an organic group.  
WO/2011/076784A2
The present invention relates to a compound of formula (I): Formula (I), wherein: - n is 0, 1 or 2; - A is in particular CH or N; - X is in particular CO, SO2, CS, and R1 is in particular H, - R2 is a group of formula NR3R4 or OR5, R3 an...  
WO/2011/017201A3
Described herein is the DP2 antagonist [2'-(3-benzyl-1-ethyl-ureidomethyl)-6-methoxy-4'-trifluorome thyl-biphenyl-3-yl]-acetic acid, or a pharmaceutically acceptable salt thereof. Also described are methods of preparing the DP2 antagonis...  
WO/2011/071078A1
Provided is an oligonucleotide derivative, the 3′ end of which is chemically modified with two skeletons selected from among benzene skeletons and pyridine skeletons. Said oligonucleotide derivative can be easily synthesized in a small...  
WO/2011/039735A3
The present invention relates to the medical use of the compound of formula 1, 2, 3 or 4:  
WO/2011/022489A3
The invention provides for novel (bis)urea and (bis)thiourea compounds which are inhibitors of lysine- specific demethylase 1 (LSD1). Such compounds may be used to treat disorders, including cancer.  
WO/2011/066414A1
The present invention provides arachidonic acid (AA) analogs and compositions containing those analogs as active agents for use in analgesic treatments. Various methods of r manufacturing the inventive compounds are provided and pharmace...  
WO/2010/144378A3
The present invention provides a compound of general Formula (I) having histone deacctylase (HDAC) inhibitory activity, a pharmaceutical composition comprising the compound, and a method useful to treat diseases using the compound.  
WO/2011/039735A2
The present invention relates to the medical use of the compound of formula 1, 2, 3 or 4:  
WO/2011/040509A1
In order to provide a low molecular weight compound that has p38MAPK inhibitory activity and the accompanying TNFα production suppression activity and that has a favorable pharmacokinetic profile as a pharmaceutical and decreased hepato...  

Matches 201 - 250 out of 6,127