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Patent Searching and Data


Matches 251 - 300 out of 6,220

Document Document Title
WO/2011/159137A3
The present invention relates to a novel thiourea or urea derivative, a preparation method thereof, and a pharmaceutical composition for preventing or treating AIDS, containing the same as an active ingredient. According to the present i...  
WO/2012/054996A1
The present invention relates to functionalized aryl and/or heteroaryl urea compounds of general formula (I) and (II), and also salts and/or solvates and polymorphs thereof which can inhibit protein kinases from the MAPK family and also ...  
WO/2012/050041A1
The present invention provides a pest control agent, an acaricide, or a bactericide that contains, as the active ingredient thereof, at least one type of compound selected from aryloxyurea compounds represented by formula (V) (wherein R1...  
WO/2012/050482A1
Carbamide is produced at a high temperature and pressure in a plant which comprises a high pressure section including a reactor, a stripper, a condenser and a scrubber. Ammonia and carbon dioxide are reacted in the reactor to form a reac...  
WO/2012/028676A1
The invention relates to new compounds of the formula (I) to their use as medicaments, to methods for their therapeutic use and to pharmaceutical compositions containing them.  
WO/2011/122917A3
The present invention relates to an octahydrobinaphthol derivative which recognizes an amino acid and amino alcohol in a chiral-selective manner, converts L-amino acid into D-amino acid, and performs optical resolution on an amino acid a...  
WO/2012/004549A1
A compound of formula I-0, and its pharmaceutically acceptable salt or salts and physiologically hydrolysable derivatives in free form or salt form: wherein Z1 is C1-C4 linear or branched alkyl or alkenyl; R4 is selected from unsubstitut...  
WO/2011/157612A2
The invention relates to novel compounds derived from amino acids of formula (I) and also to cosmetic or dermatological compositions containing them and to their use as agents for treating human perspiration in a cosmetic composition. Th...  
WO/2011/159137A2
The present invention relates to a novel thiourea or urea derivative, a preparation method thereof, and a pharmaceutical composition for preventing or treating AIDS, containing the same as an active ingredient. According to the present i...  
WO/2011/157611A2
The invention relates to novel compounds derived from amino acids of formula (I) and also to cosmetic or dermatological compositions containing them and to their use as agents for treating human perspiration in a cosmetic composition. Th...  
WO/2011/140680A1
The present invention discloses compounds of formula (I), isomers, pharmaceutical salts or solvates thereof. The present invention also discloses a composition comprising the compounds of formula (I), isomers, pharmaceutical salts or sol...  
WO/2011/140832A1
The present invention discloses a compound of general formula (I), or isomer, pharmaceutically acceptable salt and solvate thereof, as well as composition, medicinal use, and preparative method thereof. Said composition further comprises...  
WO/2011/076784A3
The present invention relates to a compound of formula (I): Formula (I), wherein: - n is 0, 1 or 2; - A is in particular CH or N; - X is in particular CO, SO2, CS, and R1 is in particular H, - R2 is a group of formula NR3R4 or OR5, R3 an...  
WO/2011/064556A3
There is provided a mixture having a freezing point of up to 100°C formed by a process comprising the step of contacting: (A) from 1 to 2 equivalents of a compound of formula (I) AIX3 (I) wherein each X independently represents Cl, Br o...  
WO/2011/136231A1
Disclosed is a process for producing a high-purity bisaminophenylalkylurea as the desired compound in high yield while attaining a high volumetric efficiency and generating little by-product. A (nitrophenyl)alkylamine hydrohalogenide rep...  
WO/2011/131576A1
Tranylcypromine derivatives useful as therapeutic agents, particularly for the prevention and/or treatment of diseases and conditions associated with the activity of histone demethylases LSD1 and LSD2, such as the diseases characterized ...  
WO/2011/122917A2
The present invention relates to an octahydrobinaphthol derivative which recognizes an amino acid and amino alcohol in a chiral-selective manner, converts L-amino acid into D-amino acid, and performs optical resolution on an amino acid a...  
WO/2010/149760A3
The present invention concerns prodrugs of mexiletine (and mexiletine's active metabolite) with amino acids or peptides and pharmaceutical compositions containing such prodrugs. Methods for providing pain relief, treating arrhythmia, dec...  
WO/2011/113368A1
A fluoro-substituted deuterated diphenylurea compound, especially 4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluoro phenoxy)- 2-(N-1',1',1'-d3-methyl)picolinamide, preparing method and use for treating or preventing tumor and ...  
WO/2011/113367A1
Methods and processes for preparation and production of deuterated ω-diphenylure are disclosed. Especially, a kind of deuterated ω-diphenylurea compounds which can inhibit phosphokinase and the preparation method of N-(4-chloro-3-(trif...  
WO/2011/108690A1
The disclosed composition containing a compound represented by general formula (I) (refer to the Description for the definitions of the symbols used in the formula), or a salt thereof, has excellent CaSR agonist effects and provides phar...  
WO/2011/108724A1
An object is to provide a CaSR agonist agent that has excellent CaSR agonist effects, and particularly, a pharmaceutical product that can prevent or remedy diabetes or obesity by the effect of CaSR activation. The aforementioned object i...  
WO/2011/018170A3
The object of the present invention is to provide novel carboxamides which exhibit an excellent pesticidal activity as pesticides. Disclosed are the carboxamides represented by the following Formula (I) wherein each substituent is as def...  
WO/2011/084106A1
Disclosed herein is a compound of structure (A): In this compound, X is either O or S, R1 is a rigid group, R2 is a hydrophilic group such that (A) is capable of self-assembly in water, and R3 is an organic group.  
WO/2011/076784A2
The present invention relates to a compound of formula (I): Formula (I), wherein: - n is 0, 1 or 2; - A is in particular CH or N; - X is in particular CO, SO2, CS, and R1 is in particular H, - R2 is a group of formula NR3R4 or OR5, R3 an...  
WO/2011/017201A3
Described herein is the DP2 antagonist [2'-(3-benzyl-1-ethyl-ureidomethyl)-6-methoxy-4'-trifluorome thyl-biphenyl-3-yl]-acetic acid, or a pharmaceutically acceptable salt thereof. Also described are methods of preparing the DP2 antagonis...  
WO/2011/071078A1
Provided is an oligonucleotide derivative, the 3′ end of which is chemically modified with two skeletons selected from among benzene skeletons and pyridine skeletons. Said oligonucleotide derivative can be easily synthesized in a small...  
WO/2011/039735A3
The present invention relates to the medical use of the compound of formula 1, 2, 3 or 4:  
WO/2011/022489A3
The invention provides for novel (bis)urea and (bis)thiourea compounds which are inhibitors of lysine- specific demethylase 1 (LSD1). Such compounds may be used to treat disorders, including cancer.  
WO/2011/066414A1
The present invention provides arachidonic acid (AA) analogs and compositions containing those analogs as active agents for use in analgesic treatments. Various methods of r manufacturing the inventive compounds are provided and pharmace...  
WO/2010/144378A3
The present invention provides a compound of general Formula (I) having histone deacctylase (HDAC) inhibitory activity, a pharmaceutical composition comprising the compound, and a method useful to treat diseases using the compound.  
WO/2011/039735A2
The present invention relates to the medical use of the compound of formula 1, 2, 3 or 4:  
WO/2011/040509A1
In order to provide a low molecular weight compound that has p38MAPK inhibitory activity and the accompanying TNFα production suppression activity and that has a favorable pharmacokinetic profile as a pharmaceutical and decreased hepato...  
WO/2011/034078A1
Disclosed is a compound which is useful as the active ingredient of a medicinal composition, in particular, a medicinal composition for preventing and/or treating a VAP-1 associated disease. As the results of intensive studies on compoun...  
WO/2010/129057A8
The present invention is directed to a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. The variables for Structural Formula I are defined herein. Also described is a pharmaceutical compositi...  
WO/2011/022489A2
The invention provides for novel (bis)urea and (bis)thiourea compounds which are inhibitors of lysine- specific demethylase 1 (LSD1). Such compounds may be used to treat disorders, including cancer.  
WO/2011/001122A3
The invention relates to pyrazole derivatives of the general formula (I), where X is chlorine or fluorine. The invention also relates to a method for preparing same and to the therapeutic use thereof.  
WO/2011/019928A1
A modular system and method for producing urea from stranded natural gas includes removal of foreign particulate matter to obtain a substantially homogeneous gas. The gas is processed by controlling the quality of the stranded natural ga...  
WO/2010/065902A3
A compound of Formula (I), a pharmaceutically acceptable salt, or solvate thereof, complexes with metals such as rhenium, technetium, and others to provide a complex for imaging tissues or treating disease, particularly where the metal i...  
WO/2010/080795A8
Provided is a complex of hydrogen peroxide and at least one compound represented by Formula (I): wherein X is (i), -C(R3)3, -C=C(R3), -O(R3), -N(R3)2, or -S(R3); and R1, R2, and R3 are each independently selected from H, alkyl, alkenyl, ...  
WO/2011/017201A2
Described herein is the DP2 antagonist [2'-(3-benzyl-1-ethyl-ureidomethyl)-6-methoxy-4'-trifluorome thyl-biphenyl-3-yl]-acetic acid, or a pharmaceutically acceptable salt thereof. Also described are methods of preparing the DP2 antagonis...  
WO/2010/120138A3
The present invention relates to a salicylaldehyde chiral compound (chemical formula 1) and a naphtholaldehyde chiral compound (chemical formula 2), wherein a –OH group and a carbonyl group are adjacent to each other on a benzene ring....  
WO/2010/112946A4
The invention relates to adamantane bisurea derivatives and their use. Adamantane bisurea derivatives are obtained by reaction of adamantane diamine with appropriate isocyanate, or by in situ preparation of adamantane isocyanate from ada...  
WO/2010/129057A3
The present invention is directed to a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. The variables for Structural Formula I are defined herein. Also described is a pharmaceutical compositi...  
WO/2011/001122A2
The invention relates to pyrazole derivatives of the general formula (I), where X is chlorine or fluorine. The invention also relates to a method for preparing same and to the therapeutic use thereof.  
WO/2010/132670A3
The present invention is directed to a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. The variables for Structural Formula (I) are defined herein. Also described is a pharmaceutical composi...  
WO/2010/150255A1
Novel compounds and pharmaceutical compositions are provided. In one aspect of the invention the compounds may be utilized in medical practice, for example, in treatment of cancer and immune disorders. In another aspect of the invention ...  
WO/2010/143409A1
Disclosed are: a process for producing a salt of an optically active thiazolylalanine derivative which has a desired configuration by converting a thiazolylalanine derivative into a salt thereof and crystallizing a compound having one of...  
WO/2010/144055A1
The invention relates to compounds represented by the general formula (I): and pharmaceutically acceptable salts thereof, wherein n is an integer from 1 to 5; p is an integer from 0 to 4; R1 is selected from the group consisting of a hyd...  
WO/2010/110555A3
The present invention relates to a method for obtaining optically pure amino acids, including optical resolution and optical conversion. The method of the present invention significantly shortens the time taken for optical transformation...  

Matches 251 - 300 out of 6,220