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JP2005167175A |
To provide an organic dopant that is easily handled in the manufacturing process and is capable of fabricating organic semiconductors with high reproducibility.To dope organic semiconductor matrix materials and change the electrical prop...
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JP2005515228A |
The invention relates to a method for producing pure racemic, R- or S-thioctic acid or mixtures thereof by reacting 6,8-disubstituted octanoic acid or their salts or esters with sulfides, sulfur or sulfites.
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JP2005511680A |
A description is given of a process for preparing dihydroxycarboxylic esters and of an overall process for preparing R-(+)-alpha-lipoic acid.
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JP2005506969A |
The invention relates to new modifications of the trometamol salt of R-thioctic acid of the formula I, processes for their production, pharmaceutical preparations containing these modifications, and their medical application.
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JP3628054B2 |
PURPOSE: To obtain a new polythiol derivative useful as a raw material for plastic lenses comprising the sulfur-containing urethane resin, low in optical diffusion, and excellent in high refractive index, heat resistance, light weight, c...
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JP2005506091A |
The invention relates to a method for the production of (R)- or (S)-8-chloro-6-hydroxyoctanoic acid alkyl esters of the general formula (R)-II or (S)-II in which R has the meaning C1-4-alkyl, from 8-chloro-6-oxooctanoic acid alkyl esters...
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JP3622231B2 |
A 1,1,2-trifluoro-2-(trans-4-substituted cyclohexyl)ethylene of the formula (1): R-(A)m-Cy-CF=CF2 (1> wherein R is a C1-10 alkyl group, a halogen atom or a cyano group, provided that in the case of the alkyl group, an oxygen atom may be ...
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JP3603177B2 |
To obtain a new urea derivative having an inhibitory action on TNF-α production, useful as a therapeutic agent for various diseases, especially an autoimmune disease such as chromic rheumatoid arthritis, etc. This compound is shown by f...
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JP3602127B2 |
A method of reducing the rate of mammalian hair growth includes topically applying a composition containing a sulfhydryl reactive compound to the skin.
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JPWO2003016265A1 |
The present invention provides a compound represented by the following formula, which has an excellent PPAR agonistic action. In the formula, a, b, c are 0 to 4; R1 to R6 are hydrogen atoms, hydroxyl groups, cyano groups, halogens, etc ....
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JP2004331520A |
To provide a method for efficiently producing 2,5-bis(isocyanatomethyl)-1,4-dithianes without problems such as post-treatment and to provide an intermediate for production and a method for producing the same.The method for producing the ...
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JP3584228B2 |
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JP2004530684A |
The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for t...
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JPWO2002100819A1 |
In the following formula (I) [in the formula, R1 is a C1-6 alkoxy group or the like, R2 is a hydrogen atom,-(CH2) m-N (R6) (R7) (m is an integer of 1 to 4, R6 is a hydrogen atom, C1-4 alkyl group, etc., R7 represents hydrogen atom, etc.)...
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JP2004256398A |
To provide a method for purifying a mixture containing BIMD [2,5-bis(isocyanatomethyl)-1,4-dithiane] with which the high-purity BIMD with slight discoloration can be obtained and to provide a method for industrially advantageously produc...
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JP2004525894A |
The invention relates to bis(alkylthio)carbenium salts of the formula Iwith the stated definitions for R<1>, R<2>, R<3 >and Y<->,and to a process for the preparation thereof. The compounds according to the invention are advantageously su...
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JP2004523508A |
The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant inventive are ligands for estrogen receptors and as such may be useful for t...
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JP3548967B2 |
Sulfonium compounds of the formula 1 or 2 are described: in which R denotes a mononuclear cycloalkyl radical having 3 to 8 ring carbon atoms or a mononuclear cycloalkyl radical having 3 to 8 ring carbon atoms to which at least one furthe...
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JP2004203790A |
To obtain a recording material which has excellent preservability of a ground and an image, especially excellent heat resistance of a ground and plasticizer resistance of an image.The (thio)urea compound is represented by general formula...
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JP2004168706A |
To provide a bactericidal or insecticidal agent for agriculture and horticulture which is highly effective even when used in a small amount and which is highly safe for object crops.A phenyl carbamate compound represented by formula (1) ...
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JP2004159664A |
To provide a method of screening a substance for an ability to effect the formation of a retinoid X receptor homodimer comprising combining the substance and a solution containing the retinoid X receptor and determining the presence of h...
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JP2004516339A |
Catalyst compositions useful for the polymerization of olefins are disclosed. These compositions comprise a Group 8-10 metal complex comprising a bidentate or variable denticity ligand comprising one or two nitrogen donor atom or atoms i...
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JP2004514716A |
The present invention relates to a process for the preparation of R- and S-lipoic acid and R- and S-dihydrolipoic acid comprising (a) reaction of where MS is SO2-R' and R and R' independently of one another are C1-C6-alkyl, C3-C8-cycloal...
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JP2004511502A |
The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for t...
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JP2004107334A |
To provide a method for producing an isocyanate compound having less discoloration industrially advantageously.This method for producing the isocyanate compound by introducing phosgene into an organic solvent solution of a carbonate salt...
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JP2004509856A |
Processes for the preparation of R-lipoic acid or S-lipoic acid comprising a process step selected from a) distillation of dihydrolipoic acid, b) reaction of or its stereoisomer, where Ms is SO2-R' and R and R' independently of one anoth...
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JP3512379B2 |
To provide a piezoelectric element, which has very high piezoelectric characteristic, is superior in vibration transfer characteristic between ceramic base material and a piezoelectric material, and can realize miniaturization and high d...
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JP2004091417A |
To provide a new hydrolysis method for a thioester compound which realizes hydrolysis using an acid catalyst even in the absence of an organic solvent, while enabling the catalyst to be easily recovered and reused as the catalyst, and to...
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JP2004505104A |
The invention relates to a process for the preparation of compounds of the general formula I in which R1 represents a C1-C20-alkyl group, a C3-C12-cycloalkyl group, a C7-C12-aralkyl group or a mono- or bi-nuclear aryl group, in which a k...
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JP3491845B2 |
PURPOSE: To provide a control agent composition for controlling plant-pathogenic bacteria and fungi, which consists of a combination of a well-known bactericidal/fungicidal compound and another well-known specific bactericidal/fungicidal...
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JP2004002250A |
To provide a fungicidal insecticide which is used for agriculture and horticulture, has a high potency at a low dose, and has high safety for target crops.This heterocyclic iminophenyl compound represented by the formula [A is a heterocy...
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JP2004002820A |
To obtain a high refractive index resin with excellent physical properties such as transparency, color, heat resistance and impact resistance.A polymer composition for the high refractive index resin is composed of dithioacetal, dithioke...
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JP2003535115A |
The present invention relates to the use of lipoic acid, lipoic acid derivatives or salts thereof having an (R)-enantiomer-excess in cosmetic compositions for skin or hair and for the preparation of dermatological compositions for the tr...
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JP3470692B2 |
To provide an aminobutanoic acid derivative inhibiting matrix metalloproteinase and useful for the prevention and/or treatment of rheumatism, arthrosteitis, pathologic bone resorption, osteoporosis, periodontosis, interstitial nephritis,...
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JP2003532703A |
Novel compounds of formulawherein the substituents are defined as in the specification and are useful for inhibiting neuronal NO synthase or inducible NO synthase as well as inhibiting lipidic peroxidation.
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JP2003532674A |
The present invention relates to the use of lipoic acid and C1 donors, in particular S-adenosylmethionine and/or 5-methyltetrahydrofolate, for the treatment of central nervous system disorders, to compositions with a corresponding active...
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JP2003531934A |
Catalyst compositions useful for the polymerization or oligomerization of olefins are disclosed. Certain of the catalyst compositions comprise N-pyrrolyl substituted nitrogen donors. Also disclosed are processes for the polymerization or...
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JP2003531172A |
The invention concerns the use of anethole-dithiolethione for producing a medicine for preventing drug-induced tendon toxicity.
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JP2003286283A |
To provide a resin monomer capable of forming a dielectric film suitable for an electronic part.This thioether derivative is expressed by following chemical formula (1). By using the thioether derivative as the resin monomer, the dielect...
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JP2003286168A |
To provide a skin care preparation having elastase inhibiting action and melanogenesis suppressing action and useful as a skin cosmetic, an antiwrinkle preparation, a whitening agent and an agent for the prevention and treatment of spot,...
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JP2003267968A |
To provide a photo acid generator, one component of a chemical amplification photo resist which has spectral sensitivity in the visible light region, especially argon laser light (488 nm or 514 nm) and can improve workability.A photosens...
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JP2003527391A |
A compound having a formula selected from the group consisting of wherein the substituents are defined as in the specification. The compounds are useful as intermediates in the preparation of compounds of formula (I), which are useful fo...
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JP2003238562A |
To obtain a new compound which has a high refractive index, a high Abbe's number, excellent heat resistance, excellent transparency, and the like, and to provide a method for efficiently producing the same.The subject cyclic disulfide co...
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JP2003212831A |
To provide a compound of formula (1) inhibiting matrix proteinase and useful for preventing and/or treating rheumatoid arthritis, osteoarthritis, pathological bone resorption, osteoporosis, periodontal disease, institutional nephritis, a...
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JP2003519165A |
Active acne and acneiform scars are treated by topical application of a composition containing lipoic acid and/or a lipoic acid derivative such as dihydrolipoic acid, a lipoic or dihydrolipoic acid ester, a lipoic or dihydrolipoic acid a...
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JP2003519176A |
Use of certain nitrate ester compounds or pharmaceutically acceptable salts thereof in the manufacture of a medicament for treating pain or providing analgesia.
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JP3415389B2 |
To stably and selectively produce the subject compound having a refractive index higher than and an Abbe's number comparable to those of the polyol of a raw material b reacting a specific polyol with sulfur in the presence of a basic cat...
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JP2003515479A |
The use of a compound of formula (A), which comprises a group of sub-formula (I) where R1, R2, R3, R4, R5, R6, X1 and Y1 are various specified organic groups wherein at least one of said groups has sufficient electron whitdrawing propert...
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JP3404435B2 |
PURPOSE: To obtain a clathrate compound comprising thioctic acid and a cyclodextrin (derivative) and being capable of giving a toothpaste or an effervescent tablet which enables the peroral administration of a high dosage of thioctic aci...
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JP3401623B2 |
PURPOSE: To obtain a skin cosmetic useful for preventing chapped skin such as cracks and chaps and aging of skin, comprising an indenemalonate derivative as an active ingredient. CONSTITUTION: This skin cosmetic contains 0.0001-20wt.%, p...
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