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Matches 451 - 500 out of 3,839

Document Document Title
WO/1999/052850A1
The present invention relates to an oxidation which converts a primary or secondary alcohol of Formula (II) to an acid or ketone of Formula (I) with periodic acid and a catalytic amount of a chromium reagent.  
WO/1999/052849A1
The present invention relates to the oxidation of a primary alcohol of Formula (II) to the carboxylic acid of Formula (I): R?1¿CH¿2?OH$m(7)R?1¿CO¿2?H.  
WO/1999/051561A1
Process for the preparation of 3-bromoanisole comprising methoxydenitrating 3-bromonitrobenzene in the presence of a phase-transfer catalyst (PTC), and the preparation of 3-bromonitrobenzene by the bromination of nitrobenzene with bromin...  
WO/1999/047474A1
This invention relates to a novel, inventive process for the preparation of biphenyls or aromatic olefins by coupling reactions of the Suzuki coupling and Heck coupling type, using allylpalladium catalysts of the $g(m)-halo(triisopropylp...  
WO/1999/042433A1
Disclosed is a process for the nitration of aromatic compounds using oxygen activated by an inorganic catalyst and nitrogen dioxide. Since the present invention does not use concentrated nitric acid nor concentrated sulfuric acid used in...  
WO1998039099A9
The present invention provides apparatus and methods for the synthesis of combinatorial chemical libraries. The apparatus comprises a plurality of reaction vessels having an inner surface, an outer surface, a first opening, and a second ...  
WO1999020395A9
The present system is useful for the synthesis of chemical compounds and can be used for solid state or liquid chemistries. In one embodiment, the system (10) includes a reagent delivery/vent unit (20) and a chemical processing unit (30)...  
WO/1999/035117A1
The subject invention involves processes for making 2,4-difluoro-3-Q1-benzoic acid, wherein Q1 is derived from an electrophilic reagent, comprising the steps of: (a) treating 1-bromo-2,4-difluorobenzene with a strong, non-nucleophilic ba...  
WO/1999/022858A1
A method of reacting an aromatic compound with an immiscible reacting agent involves the passage of the reactant along a flow path having a width of from 10 to 1000 $g(m)m in such a way that essentially laminar flow of the reactant takes...  
WO/1999/023061A1
According to the invention, a quantity of 0.5 to 20,000 ppm of one or more surface active substances from the group of anionic, cationic, zwitterionic or non-ionic is added to the reaction mixture during the conversion of aromatic compou...  
WO/1999/019275A1
A process for electrophilic substitution of an aromatic compound, comprising contacting said aromatic compound, a precursor of the desired substituent and an aqueous reagent containing zinc halide, at an elevated temperature.  
WO1998056506A9
Systems and methods for synthesizing chemical compounds using a plurality reaction vessels (16). In particular, of holding a plurality of reaction vessels for parallel synthesis of multiple discrete compounds or for combinatorial librari...  
WO/1999/012886A1
The invention relates to a method for producing a dinitronaphthalene-isomer mixture by nitration of nitronaphthalene. According to said method, nitronaphthalene is reacted in a solvent of formula (I), wherein X represents nitrogen or sul...  
WO/1999/012919A1
Disclosed is a novel process and novel intermediates to prepare [R-(R*,R*) ]-N-[3-[1-[5, 6-dihydro-4-hydroxy -2-oxo-6-(2-phenylethyl) -6-propyl-2H-pyran-3- yl]propyl]phenyl]-5- (trifluoromethyl)-2- pyridinesulfonamide (XIX) which is a pr...  
WO/1999/012887A1
The invention relates to a method for producing a dinitronaphthalene-isomer mixture by nitrating nitronaphthalene. The invention is characterized in that nitronaphthalene is optionally reacted in an inert organic solvent with 1 to 20 tim...  
WO/1999/010527A2
The invention relates to a method for isolating anionic organic substances from aqueous systems using polymer nanoparticles with cationic pH-sensitive surface groups. Extraction can be carried out directly from diluted solutions, biologi...  
WO/1999/008995A1
The invention concerns a method for treating an aqueous solution derived from sluicing of crude mononitrated or dinitrated aromatic compounds obtained by nitration of the corresponding aromatic compounds, consisting in: (a) contacting sa...  
WO/1999/006339A1
The invention concerns a method for preparing substituted benzyl bromides of general formula (I), wherein at least one substituent R?1-5¿ represents an electroattractive group, such as fluorine, chlorine, bromine, C¿1?-C¿4? alkoxycarb...  
WO/1999/005087A1
A process for the preparation of a compound of general formula (I), wherein R?1¿ is hydrogen or C¿1?-C¿6? alkyl, C¿2?-C¿6? alkenyl or C¿2?-C¿6? alkynyl, any of which may optionally be substituted with one or more substituents sele...  
WO/1999/003802A1
The present invention provides a method of substituting a carbonyl compound with fluorine at the $g(a)-position, comprising reacting the carbonyl compound with a fluorinating agent in the present of a metal-containing catalyst. The react...  
WO/1998/055446A1
The preparation of aromatic ketones substituted with a thioether group at the ortho position is accomplished by the initial reaction of an aromatic nucleus substituted with a halide and an ortho nitro group with a nitroalkane in the pres...  
WO/1998/046547A1
A process is disclosed for preparing 2-aryl-substituted indenes by reacting an indene with an arene compound substituted with an halogen atom, preferably a iodine atom, or with an organosulphonate group, said reaction being carried out i...  
WO/1998/046557A1
The invention relates to aromatic amines which are produced by catalytically hydrogenating corresponding aromatic nitrocompounds in a gaseous phase. Hydrogenation is carried out in the presence of catalysts which contain palladium, vanad...  
WO/1998/042653A1
A process for producing carboxylic acid esters by reacting an aldehyde with an alcohol in a liquid phase in the presence of molecular oxygen and a catalyst composed of at least palladium and X (which is bismuth and/or lead) supported by ...  
WO/1998/042654A1
A process for separately isolating 3-nitro-o-toluic acid and 5-nitro-o-toluic acid from a mixture of both, which comprises adding an aromatic organic base such as aniline or pyridine to the mixture to form the corresponding salts, throwi...  
WO/1998/040347A1
A process for the purification of a compound of general formula (I), wherein R1 is hydrogen or C�1?-C�6? alkyl, C�2?-C�6? alkenyl or C�2?-C�6? alkynyl, any of which may optionally be substittuted with one or more substituents...  
WO/1998/035932A1
A process for producing 3-nitro-o-toluic acid which comprises oxidizing 3-nitro-o-xylene with oxygen or an oxygenic gas in a solvent based on a lower aliphatic carboxylic acid in the presence of a heavy metal catalyst and a reaction acce...  
WO/1998/032532A1
A catalyst for halogen-fluorine exchange reactions of aromatic compounds essentially consists of a mixture of one or more compounds (a) and at least one compound (b), (c) and/or (d). (a) is an amidophosphonium salt of formula (I), in whi...  
WO/1998/030329A1
At least one functional group selected between nitro and carboxyl groups can be introduced into a substrate by bringing the substrate into contact with at least one reactant selected from among (i) nitrogen oxides and (ii) carbon monoxid...  
WO/1998/025918A1
The invention concerns products of formula (I) in which Ar represents an aromatic monocyclic or bicyclic radical comprising 5 to 10 carbon atoms and optionally 1 or 2 heteroatoms selected among the atoms of nitrogen, oxygen or sulphur, s...  
WO/1998/024753A1
Optically active 1-(substituted phenyl)-2-nitro alcohol derivatives represented by general formula (1) and a process for preparing the same, and 1-(substituted phenyl)-2-amino alcohol derivatives represented by general formula (2) and a ...  
WO/1998/019978A1
A process for the nitration of an aromatic or heteroaromatic compound with a nitrating agent comprising nitric acid or a mixture of nitric and sulphuric acids, characterised in that nitration is performed in a solvent comprising at least...  
WO/1998/016222A1
The present invention relates to novel itermediates of formula (1) wherein the wavy bond ($m(k) $m(k)) represents the racemate, the (R)-enantiomer or the (S)-enantiomer; and R is hydrogen, a carboxyl-protecting group or a cation of an ad...  
WO/1998/016486A1
A process for the preparation of a substituted aromatic compound in which a chloroaromatic compound and an alkyl-, alkenyl- or aryl-boronic acid, ester or anhydride are coupled in the presence of palladium and a lipophilic aliphatic phos...  
WO/1998/009937A1
A process for preparing 1,2- and 1,3-dinitrate esters from polyols containing 1,2- or 1,3-diol fragments involves using an alkyl or aryl boronic acid to form a cyclic boronate ester derivative which is then reacted with dinitrogen pentox...  
WO/1998/005610A2
A process is disclosed for preparing fluorine-containing compounds by reacting a compound which contains a halogen that can be replaced by fluorine with a fluoride or a mixture of fluorides of general formula (I): MeF, in the presence of...  
WO/1998/002408A1
The invention concerns a method of nitrosation of a phenolic compound substituted by an electro-attracting group.The invention also concerns a method of nitration of a phenoic compound substituted by an electro-attracting group. The nitr...  
WO/1997/046511A1
Method and compositions for treating a patient having a neurological disease or disorder, such as stroke, head trauma, spinal cord injury, spinal cord ischemia, ischemia- or hypoxia-induced nerve cell damage, epilepsy, anxiety, neuropsyc...  
WO/1997/045397A1
The present invention describes certain alkyloxyamino-substituted fluorenones which inhibit protein kinase C, as well as pharmaceutical compositions including these compounds and methods of using these compounds to control protein kinase...  
WO/1997/038967A1
A process is disclosed for removing a light organic compound from a liquid composition comprising said light organic compound in admixture with a nitroaromatic compound, said light organic compound having a partial vapor pressure in said...  
WO/1997/038770A1
Reduction of dinitrotoluene impurity in water is achieved by distillation in the presence of nitric acid. A suitable process for such reduction comprises (a) contacting said composition with nitric acid to provide a nitric acid-containin...  
WO/1997/033846A1
The invention concerns a process for preparing nitrobiphenylene of formula (I) wherein m stands for 1 or 2, R means halogen, R' or OR', R' being a C-organic group which can carry groups which are inert in the reaction conditions, n stand...  
WO/1997/032832A1
The production of fluorinated aromatic compounds of general formula (I), in which W, X, Z, R1 and R2 have the meanings given in the description, from corresponding C1 or Br-containing compounds with fluorides, e.g. KF, with halogen excha...  
WO/1997/028122A2
The invention relates to a process for preparing compounds of formula (I), wherein R2 is lower alkyl; or phenyl optionally substituted by from one to five groups which may be the same or different selected from lower alkyl, lower haloalk...  
WO/1997/027846A1
Compounds of formula (I), wherein R5 is an [A]-CH3, -[A]-C(OH)ZZ' or -[A]-C(O)Z" grouping where -[A]- is an alkylene, alkenylene or alkynylene radical or a single bond, and Z, Z' and Z" are a hydrogen atom or an optionally substituted al...  
WO/1997/022590A1
A method of nitrating electron-deficient carbocyclic or heterocyclic aromatic compounds such as pyridines, diazines and triazines and benzenoid aromatics having electron-withdrawing substituents involves first reacting the aromatic speci...  
WO/1997/019917A1
A novel method for preparing (+)compactin and (+)mevinolin analog compounds having a 'beta'-hydroxy-'delta'-lactone grouping is disclosed. The method for preparing said compounds uses novel reaction intermediates. Said reaction intermedi...  
WO/1997/016729A1
Combinatorial libraries are disclosed which are represented by Formula (I), wherein S is a solid support; T'-L- is an identifier residue; and -L'-II' is a ligand/linker residue. These libraries contain dihydrobenzopyrans of Formula (II) ...  
WO/1997/010199A1
A process for the preparation of a compound of general formula (I) wherein R1 is hydrogen or C1-C6 alkyl, C2-C6 alkenyl or C2-C6 alkynyl (any of which may optionally be substituted with one or more substituents selected from halogen and ...  
WO/1997/010200A1
A process for the purification of a compound of general formula (I), wherein R1 is hydrogen or C1-C6 alkyl, C2-C6 alkenyl or C2-C6 alkynyl (any of which may optionally be substituted with one or more substituents selected from halogen an...  

Matches 451 - 500 out of 3,839