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Matches 1 - 50 out of 3,772

Document Document Title
WO/2022/167070A1
The present invention relates to a process for preparing hexanoic acid, 6-(nitrooxy)-, (1S,2E)-3-[(1R,2R,3S,5R)-2-[(2Z)-7-(ethylamino)-7-oxo-2-hept en-1-yl]-3,5-dihydroxycyclopentyl]-1-(2-phenylethyl)-2-prope n-1-yl ester of formula (I)....  
WO/2022/155936A1
Disclosed in the present invention is a method for synthesizing an aryl benzyl ether compound, i.e., synthesizing a corresponding aryl benzyl ether compound by means of an oxidative coupling reaction of a phenolic compound and a toluene ...  
WO/2022/155932A1
Disclosed is an application of an iron (III) complex containing 1,3-di-tert-butyl imidazolium cation in synthesizing arylbenzyl ether compounds. Specifically, di-tert-butyl peroxide is used as an oxidant, and a corresponding arylbenzyl e...  
WO/2022/134297A1
The present invention relates to a preparation method for a carboxylate ester compound, comprising: under the catalysis of a nitrite ester, reacting carboxylic acid and methanol in air, so as to obtain an ester compound. The preparation ...  
WO/2022/127038A1
Disclosed herein is a method for producing dinitronaphthalene, which includes subjecting naphthalene to a nitration reaction with nitric acid in a reactor, so as to obtain a dinitronaphthalene-containing solution. The reactor includes at...  
WO/2022/100487A1
Disclosed is an amino-combretastatin derivative, and in particular a compound represented by general formula (I), a pharmaceutically acceptable salt thereof, a hydrate thereof, or a hydrate of the pharmaceutically acceptable salt thereof...  
WO/2022/101353A1
The invention relates to a process for concentrating diluted sulfuric acid (10) which may comprise at least one nitroaromatic compound and/or nitric acid as impurities, comprising: (a) feeding the diluted sulfuric acid (10) into a first ...  
WO/2022/082148A1
Processes and systems for producing isomeric mixtures of aromatic amine monomers from aromatic feeds. An example process for producing isomeric mixtures of aromatic amine monomers from aromatic feeds may include nitrating at least a port...  
WO/2022/068057A1
Provided is a continuous production method for 2,4-dinitrochlorobenzene. In the method, concentrated nitric acid, concentrated sulfuric acid, and chlorobenzene serve as raw materials; after a mixed acid solution is prepared, chlorobenzen...  
WO/2022/061920A1
A method for preparing 3',5'-dichloro-2,2,2-trifluoroacetophenone. The method comprises subjecting 3'-chloro-2,2,2-trifluoroacetophenone as a raw material to four steps, i.e. nitrification, reduction, chlorination and deamination, so as ...  
WO/2022/052683A1
The present invention provides a method for preparing a water-soluble magnolol derivative and a honokiol derivative, methods for preparing intermediates of a water-soluble magnolol derivative and a honokiol derivative, and a related mono...  
WO/2021/244136A1
Provided in the present invention is a refinement method for nitromethane. The refinement method comprises the following steps: (1) rectifying a nitromethane crude product, and collecting a gas phase fraction for condensation, thus produ...  
WO/2021/237371A1
The present application describes process for preparing an ortho-allylated hydroxy aryl compounds such as compounds of Formula (I) by reacting an allylic alcohol with a hydroxy aryl compound in the presence of aluminum compound selected ...  
WO/2021/219647A1
The present invention relates to a method for preparing paracetamol continuously, comprising a nitration step or a nitrosation step so as to obtain p-nitrophenol or p-nitrosophenol, respectively. The p-nitrophenol or p-nitrosophenol can ...  
WO/2021/214146A1
The invention relates to a safe and efficient process for the for the acylation of an α,ω-alkanediol, which can be used in the manufacture of ω-nitrooxy-C3-10alkane-1-ols. The process is safer to operators and allows to obtain advanta...  
WO/2021/214145A1
The invention relates to a safe and efficient process for the nitrate ester formation of an α,ω-C3-10alkanediol monoacylate. The process is safer to operators and allows to obtain advantageous yields on industrial scale.  
WO/2021/214144A1
The invention relates to a safe and efficient process for the hydrolysis of α,ω-C3-10alkanediol mononitrate monoacylates. The process is safer to operators and allows to obtain advantageous yields on industrial scale.  
WO/2021/214143A1
The invention relates to a safe and efficient process for the solvent removal and recovery by distillation in a process for the preparation of ω-nitrooxy-C3-10alkane-1-ols. The process is safer to operators and allows to obtain advantag...  
WO/2021/208951A1
Disclosed is a β-diketone cerium (IV) compound of formula (I). The compound has a wide absorption band, is suitable for near ultraviolet-visible region curing as a photoinitiator, and has a high sensitiveness, while also having the adva...  
WO/2021/174748A1
The present invention relates to a method for preparing a visible light catalyzed dichlorine addition product of an aliphatic olefin, comprising the following steps: using an aliphatic olefin as a substrate, using copper chloride having ...  
WO/2021/160468A1
The present invention relates to a process for the preparation of 1-[4-nitro-2-(trifluoromethyl)- phenyl]-alkanones and substituted phenoxyphenyl ketones.  
WO/2021/127743A1
The present disclosure relates to substituted hydroxystilbene compounds and derivatives, specifically 2-substituted hydroxystilbene compounds and derivatives, the synthesis of such compounds and their use in therapy.  
WO/2021/116146A1
The present invention relates to a method for continuously operating a distillation column, which is designed to separate a mixture S, which contains essentially a substance A and a substance B, which boils significantly higher than subs...  
WO/2021/089183A1
The invention relates to a process (100) and to a plant for producing monoethylene glycol (110), wherein, in a carbonylation step (21), carbon monoxide (102) is reacted with methyl nitrite (104) to form dimethyl oxalate (105) and nitroge...  
WO/2021/082752A1
The present invention provides a preparation method for 1-nitro-2-ethyl-4-fluorobenzene. The preparation method comprises the following steps: (1) performing a nitration reaction between m-fluoroacetophenone and a nitration reagent to ob...  
WO/2021/047978A1
The present invention relates to a process for the preparation of α-methyl-[4-(nitro)-2- (trifluoromethyl)]-benzyl nitrate and to the α-methyl-[4-(nitro)-2-(trifluoromethyl)]-benzyl nitrate.  
WO/2021/042411A1
Disclosed are an AKR1C3 inhibitor or a pharmaceutically acceptable salt of same, a preparation method for same, and uses thereof. A structural optimization is performed with a nonsteroidal anti-inflammatory medicament, flurbiprofen, serv...  
WO/2021/045207A1
The present invention relates to a production method for a highly reactive intermediate. The production method includes: preparing an electron-accepting active compound (1); preparing a piezoelectric material (3); and applying mechanical...  
WO/2021/031431A1
Disclosure relates to a use of a fluorination gas, wherein the elemental fluorine is present in a high concentration, for example, in a concentration of elemental fluorine, especially of equal to much higher than 15 % or even 20% by volu...  
WO/2021/001044A1
Object of the present invention is an improved process for the preparation of key intermediates for the synthesis of Eltrombopag, passing through/using intermediate 5'-Chloro-2'-hydroxy[1,1'-biphenyl]-3-carboxylic acid alkaline metal sal...  
WO/2020/248127A1
A borohydride reduction stabilizing system and a method for reducing an ester to an alcohol. The borohydride reduction stabilizing system comprises: a borohydride reducing agent and a stabilizing agent for stabilizing the borohydride red...  
WO/2020/248279A1
The present invention provides a continuous synthesis method for a substituted benzoate organic matter. The continuous synthesis method comprises: in the presence of a catalyst and an organic solvent, continuously feeding an organic matt...  
WO/2020/248278A1
The present invention provides a method for the continuous synthesis of a substituted benzoic-acid organic substance. The continuous synthesis method comprises: in the presence of catalyst and organic solvent, the organic matter represen...  
WO/2020/238862A1
The present invention provides a fluorene initiator, a photocurable composition comprising same, and an application thereof. The fluorene photoinitiator has a structure represented by formula (I) or formula (II). In the photoinitiator, o...  
WO/2020/230555A1
A method for forming a carbon-carbon bond, wherein: a reaction is performed by filling a container with a platinum group metal-loaded catalyst and having a starting material liquid permeate through the platinum group metal-loaded catalys...  
WO/2020/222041A1
This invention provides a novel method that is simple, efficient, and allows for a reliable production of fluorine- 18 (18F) radiofluorinated compounds and radiopharmaceuticals. The method comprises an "in-loop" process, where an 18F sou...  
WO/2020/212333A1
The invention relates to a continuously operating process for producing nitrobenzene, comprising the following steps: a) nitriding benzene in adiabatic conditions with sulfuric acid and nitric acid, using a stoichiometric excess of benze...  
WO/2020/212334A1
The invention relates to a continuously operating process for producing nitrobenzene, comprising the following steps: a) nitriding benzene in adiabatic conditions with sulfuric acid and nitric acid, using a stoichiometric excess of benze...  
WO/2020/164217A1
Disclosed is a process for the manufacture of fluoroaryl compounds and derivatives thereof, in particular of fluorobenzenes and derivatives thereof, and especially wherein said manufacture relates to an environmentally friendly productio...  
WO/2020/126088A1
The present invention refers to a co-crystal of Ketoprofen Lysine named Form 1, a pharmaceutical composition comprising said co-crystal, a process for its production and to its use in the treatment of pain and inflammatory diseases.  
WO/2020/127386A1
A method is provided for preparing an intermediate d having the formula: (I). The method comprising carrying out the following one-pot reaction: (II) wherein step (i) is carried out in the presence of a solvent and step (ii) is carried o...  
WO/2020/109420A1
The present invention relates to a novel process for the synthesis of mono- and bis-nitrosylated propanediols, as well as novel compositions and pharmaceutical formulations comprising said compounds. The process proceeds by reacting a co...  
WO/2020/103556A1
The present invention relates to a nitric acid reduction conversion process, the process involving bringing a raw material gas that is rich in nitric oxide into contact with a raw material liquid containing nitric acid and methanol in a ...  
WO/2020/095322A1
Disclosed herein is an efficacious process for preparation of highly purified Glycopyrrolate tosylate in high yield. The process is being cost effective, environment friendly and easily scalable to high volume industrial production.  
WO/2020/082194A1
A process for producing an alkyl nitrite is provided, comprising: mixing oxygen and a circulating gas in a pre-reactor, mixing the oxidized circulating gas and an alkyl alcohol liquid in a first esterification tower to generate alkyl nit...  
WO/2020/084094A1
The present invention relates to a process for preparing a nitrated compound, comprising the step of reacting a compound (A) comprising at least one substituted or unsubstituted aromatic or heteroaromatic ring, wherein said heteroaromati...  
WO/2020/079144A1
In a process for workup of mixed acid and wastewater from the nitration of aromatics in which the nitric acid present is converted by reaction with an aromatic under adiabatic conditions, a. at least one waste stream component selected f...  
WO/2020/053193A1
The invention relates to a safe and efficient process for the manufacture ω-nitrooxy-C3-10alkane-1-ols.  
WO/2020/053194A1
The invention relates to a process for the preparation of ω-nitroxyC3-1 0 alkane-1-ols comprising the nitration of an α,ω-C 3-10 alkanediol with a nitration agent, optionally in the presence of a nitrite trapping agent, characterized ...  
WO/2020/021323A1
A nitration reactor (10) incorporating sections of downward flow for use in preparing nitrated organic compounds. It comprises a first vertically-oriented reactor section (12), a second vertically-oriented reactor section (14), a connect...  

Matches 1 - 50 out of 3,772