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Matches 1 - 50 out of 5,381

Document Document Title
WO/2021/047978A1
The present invention relates to a process for the preparation of α-methyl-[4-(nitro)-2- (trifluoromethyl)]-benzyl nitrate and to the α-methyl-[4-(nitro)-2-(trifluoromethyl)]-benzyl nitrate.  
WO/2021/042411A1
Disclosed are an AKR1C3 inhibitor or a pharmaceutically acceptable salt of same, a preparation method for same, and uses thereof. A structural optimization is performed with a nonsteroidal anti-inflammatory medicament, flurbiprofen, serv...  
WO/2021/045207A1
The present invention relates to a production method for a highly reactive intermediate. The production method includes: preparing an electron-accepting active compound (1); preparing a piezoelectric material (3); and applying mechanical...  
WO/2021/031431A1
Disclosure relates to a use of a fluorination gas, wherein the elemental fluorine is present in a high concentration, for example, in a concentration of elemental fluorine, especially of equal to much higher than 15 % or even 20% by volu...  
WO/2021/001044A1
Object of the present invention is an improved process for the preparation of key intermediates for the synthesis of Eltrombopag, passing through/using intermediate 5'-Chloro-2'-hydroxy[1,1'-biphenyl]-3-carboxylic acid alkaline metal sal...  
WO/2020/248127A1
A borohydride reduction stabilizing system and a method for reducing an ester to an alcohol. The borohydride reduction stabilizing system comprises: a borohydride reducing agent and a stabilizing agent for stabilizing the borohydride red...  
WO/2020/248279A1
The present invention provides a continuous synthesis method for a substituted benzoate organic matter. The continuous synthesis method comprises: in the presence of a catalyst and an organic solvent, continuously feeding an organic matt...  
WO/2020/248278A1
The present invention provides a method for the continuous synthesis of a substituted benzoic-acid organic substance. The continuous synthesis method comprises: in the presence of catalyst and organic solvent, the organic matter represen...  
WO/2020/238862A1
The present invention provides a fluorene initiator, a photocurable composition comprising same, and an application thereof. The fluorene photoinitiator has a structure represented by formula (I) or formula (II). In the photoinitiator, o...  
WO/2020/230555A1
A method for forming a carbon-carbon bond, wherein: a reaction is performed by filling a container with a platinum group metal-loaded catalyst and having a starting material liquid permeate through the platinum group metal-loaded catalys...  
WO/2020/222041A1
This invention provides a novel method that is simple, efficient, and allows for a reliable production of fluorine- 18 (18F) radiofluorinated compounds and radiopharmaceuticals. The method comprises an "in-loop" process, where an 18F sou...  
WO/2020/212333A1
The invention relates to a continuously operating process for producing nitrobenzene, comprising the following steps: a) nitriding benzene in adiabatic conditions with sulfuric acid and nitric acid, using a stoichiometric excess of benze...  
WO/2020/212334A1
The invention relates to a continuously operating process for producing nitrobenzene, comprising the following steps: a) nitriding benzene in adiabatic conditions with sulfuric acid and nitric acid, using a stoichiometric excess of benze...  
WO/2020/164217A1
Disclosed is a process for the manufacture of fluoroaryl compounds and derivatives thereof, in particular of fluorobenzenes and derivatives thereof, and especially wherein said manufacture relates to an environmentally friendly productio...  
WO/2020/126088A1
The present invention refers to a co-crystal of Ketoprofen Lysine named Form 1, a pharmaceutical composition comprising said co-crystal, a process for its production and to its use in the treatment of pain and inflammatory diseases.  
WO/2020/127386A1
A method is provided for preparing an intermediate d having the formula: (I). The method comprising carrying out the following one-pot reaction: (II) wherein step (i) is carried out in the presence of a solvent and step (ii) is carried o...  
WO/2020/109420A1
The present invention relates to a novel process for the synthesis of mono- and bis-nitrosylated propanediols, as well as novel compositions and pharmaceutical formulations comprising said compounds. The process proceeds by reacting a co...  
WO/2020/103556A1
The present invention relates to a nitric acid reduction conversion process, the process involving bringing a raw material gas that is rich in nitric oxide into contact with a raw material liquid containing nitric acid and methanol in a ...  
WO/2020/095322A1
Disclosed herein is an efficacious process for preparation of highly purified Glycopyrrolate tosylate in high yield. The process is being cost effective, environment friendly and easily scalable to high volume industrial production.  
WO/2020/082194A1
A process for producing an alkyl nitrite is provided, comprising: mixing oxygen and a circulating gas in a pre-reactor, mixing the oxidized circulating gas and an alkyl alcohol liquid in a first esterification tower to generate alkyl nit...  
WO/2020/084094A1
The present invention relates to a process for preparing a nitrated compound, comprising the step of reacting a compound (A) comprising at least one substituted or unsubstituted aromatic or heteroaromatic ring, wherein said heteroaromati...  
WO/2020/079144A1
In a process for workup of mixed acid and wastewater from the nitration of aromatics in which the nitric acid present is converted by reaction with an aromatic under adiabatic conditions, a. at least one waste stream component selected f...  
WO/2020/053193A1
The invention relates to a safe and efficient process for the manufacture ω-nitrooxy-C3-10alkane-1-ols.  
WO/2020/053194A1
The invention relates to a process for the preparation of ω-nitroxyC3-1 0 alkane-1-ols comprising the nitration of an α,ω-C 3-10 alkanediol with a nitration agent, optionally in the presence of a nitrite trapping agent, characterized ...  
WO/2020/021323A1
A nitration reactor (10) incorporating sections of downward flow for use in preparing nitrated organic compounds. It comprises a first vertically-oriented reactor section (12), a second vertically-oriented reactor section (14), a connect...  
WO/2020/011626A1
The present invention refers to a crystalline 2-fluoro-3-nitrotoluene compound of formula (I), and a process for the preparation thereof. Furthermore, the present invention relates to a process for the synthesis of a compound of formula ...  
WO/2020/011817A1
The invention relates to a method for the continuous adiabatic nitration of benzene with nitric acid and sulfuric acid, the diluted sulfuric acid obtained during nitration being concentrated by flash evaporation in an evaporation device ...  
WO/2019/191363A3
Disclosed herein are improved methods for the preparation of oseltamivir, and intermediates useful thereto.  
WO/2019/216415A1
The present disclosure addresses the problem of providing a production method for a novel fluoromethyl derivative. The problem is solved by a production method that is for a fluorinated organic compound represented by formula (1) [in the...  
WO/2019/179110A1
Disclosed are a catalysis test paper prepared by compounding bacterial-cellulose-supported metal particles with plant fibers, and a preparation method therefor. Hydroxyl groups of bacterial cellulose are bonded with a nitrogen- or phosph...  
WO/2019/172184A1
Provided is a metal imide complex which has a stable structure and is able to be easily synthesized, while being capable of efficiently oxidizing various substrates. A metal imide complex which contains a metal and an imide that serves a...  
WO/2019/168269A1
The present invention relates to a bifunctional chiral organocatalytic compound having excellent enantioselectivity, a preparation method therefor, and a method for producing a non-natural gamma amino acid from a nitro compound by using ...  
WO/2019/162149A1
The present invention relates to a process for preparing the hexanoic acid, 6-(nitrooxy)-, (1S,2E)-3-[(1R,2R,3S,5R)-2-[(2Z)-7-(ethylamino)-7-oxo-2-hept en-1-yl]- 3,5-dihydroxycyclopentyl]-1-(2-phenylethyl)-2-propen-1-yl ester of formula ...  
WO/2019/159596A1
Provided is a method for preparing a coupled body represented by general formula (3), the coupled body being obtained by reacting a compound represented by general formula (1) and a compound represented by general formula (2) in the pres...  
WO/2019/154728A1
The present invention relates to processes for preparation of 1 -nitrobenzene-2- alkyloxycarbonyl-5-carboxylic acid. In particular, the present invention relates to preparation of 1 -nitrobenzene-2-alkyloxycarbonyl-5-carboxylic acid by p...  
WO/2019/111280A1
The present invention discloses a process for nitration of benzene. More particularly, the present invention discloses an efficient, environmental friendly process for the nitration of benzene using a modified solid acid catalyst.  
WO/2019/102388A1
The present invention relates to a stable pharmaceutical composition of tetrofosmin or pharmaceutically acceptable salts thereof. It also relates to a lyophilized non-radioactive kit which upon reconstitution with 99mTc -pertechnetate so...  
WO/2019/099371A1
Provided herein are compounds that are prodrugs for mesalazine. Generally, the compounds described herein correspond to a mesalazine molecule wherein the amino group is replaced by a novel protecting group. For example, in the compounds ...  
WO/2019/031774A1
The present invention relates to a method for preparing latanoprostene bunod, and an intermediate therefor. According to the preparation method of the present invention, latanoprostene bunod can be efficiently and economically prepared w...  
WO/2019/016110A1
The invention discloses a method for preparation of 5-fluoro-2-methyl-3-nitrobenzoic acid and its methyl ester by conversion of 5-fluoro-2-methylbenzoic acid with fuming nitric acid and oleum and subsequent conversion with methanol.  
WO/2019/011709A1
The invention pertains to a process for manufacturing a mixture of straight-chain higher ethyleneamines and non-straight-chain higher ethyleneamines selected from branched higher ethyleneamines and cyclic higher ethyleneamines, or the ur...  
WO/2018/187542A1
Amine-catalyzed formation of cyclic allylic nitro compounds via nitro-aldol reaction is disclosed. A greener solvent and a cheaper, more robust catalyst than in previous reports are used in the nitro-aldol reaction. After screening a ran...  
WO/2018/179808A1
Provided is a method for producing alkyl nitrite by bringing an aqueous solution containing nitric acid and an alkanol into contact with a gas containing nitrogen monoxide to generate alkyl nitrite, wherein the reaction temperature is 60...  
WO/2018/162427A1
The invention relates to a method for continuous production of nitrobenzene by means of nitration of benzene with nitric acid and sulphuric acid, in which load change (i.e. a reduction or increase in the quantity of nitric acid supplied ...  
WO/2018/149813A1
The present invention relates to a process for preparing substituted 2-nitrobiphenyls via Suzuki coupling using a palladium catalyst with specific phosphorus ligands and a solvent mixture containing water and an organic solvent which is ...  
WO/2018/141642A1
The present invention relates to an improved process for the preparation of 2-chloro-4-fluoro-5-nitrobenzotrichloride. The present invention further relates to a process for the purification of 2-chloro-4-fluoro-5-nitrobenzotrichloride, ...  
WO/2018/144101A1
Described herein are labeling agents, specifically [11C]fluoroform, [11C]difluoromethane, [11C]fluoromethyl iodide, [11C]fluoromethyl bromide, [11C]fluoromethyl chloride, [11C]fluoromethyl trifluoromethansulfonate, [11C]difluoromethyl io...  
WO/2018/141451A1
The invention relates to a method for preferably adiabatic nitriding of nitrable aromatic organic compounds (aromates) and to a corresponding system, in particular a production plant (nitration plant) for carrying out said method.  
WO/2018/116107A1
Provided are IDO inhibitor compounds of Formula (I) and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and methods for their use in the prevention and/or treatment of diseases ...  
WO/2018/107450A1
This invention provides an electrochemical process for producing a propiolactone compound comprising reacting a compound having at least one ethylenically unsaturated carbon-carbon double bond with carbon dioxide in the presence of an el...  

Matches 1 - 50 out of 5,381