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WO/2023/170657A1 |
The present disclosure relates to improved processes to recover acetonitrile from aqueous and organic waste streams, particularly those generated during oligonucleotide manufacturing processes.
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WO/2023/167325A1 |
The present invention addresses the problem of developing a metal catalyst which is suitable for continuous flow organic synthesis reaction, is excellent in durability, and has high activity. The present invention provides an immobiliz...
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WO/2023/165575A1 |
The present invention relates to a new aminoketone compound, and a preparation method therefor and the use thereof. Specifically, the compound of the present invention has a structure as shown in formula (I), wherein the definition of ea...
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WO/2023/160035A1 |
A β-elemene vinylation coupled derivative, and a preparation method therefor and the use thereof in the preparation of an antitumor drug. Provided are a β-elemene vinylation coupled derivative having a structure as represented by formu...
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WO/2023/160316A1 |
Disclosed are a pyrethroid compound containing double bonds and cyano groups, a synthesis method therefor and an application thereof. In the synthesis method, 3-formyl-2,2-dimethyl-cyclopropanoate t-butyl ester and cyanomethylphosphonate...
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WO/2023/163067A1 |
A catalyst containing: metal oxides, which are oxides of metals including molybdenum, bismuth and iron; and silica for supporting the metal oxides, wherein A/B is 0.95 to 1.04 where A is a silicon surface parameter based on SEM-EDX, and ...
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WO/2023/157862A1 |
Provided is a method for producing α-fluoroether starting from an inactivated chloride. Disclosed is a method for producing a compound represented by formula (3), the method comprising step A in which a compound represented by formula (...
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WO/2023/149559A1 |
[Problem] The present invention provides a catalyst for hydrogenation reactions, the catalyst having excellent catalyst durability and being capable of selectively hydrogenating only some functional groups and/or unsaturated bonds of an ...
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WO/2023/142460A1 |
The present invention discloses a method for synthesizing aryl phenol by means of a reaction between an aryl halide and a phenol compound under the induction of visible light, which method comprises: under the protection of an inert gas,...
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WO/2023/139597A1 |
The present invention discloses a process for extractive distillation for separating one or more hydrocarbons from a gaseous mixture. Briefly, the process disclosed in the present invention provide a process for separation of propylene f...
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WO/2023/135599A1 |
The present invention relates to an improved process for the industrial-scale production process of Tau-fluvalinate in a purified form comprising optimization of the reaction conditions by timely acid neutralization, resulting in prevent...
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WO/2023/131729A1 |
The present invention relates to a process for preparing electron-deficient olefin monomers. The process is a direct synthesis of electron-deficient monomers by catalysing a reaction between an active methylene compound and a mixture of ...
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WO/2023/122572A1 |
A process for producing acetonitrile, the process comprising dehydrating a feedstock stream comprising acetonitrile, acrylonitrile, allyl alcohol, and water (and optionally methanol) in a dehydration (first) column to yield a dehydrated ...
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WO/2023/118376A1 |
The invention concerns a process for recovering acetonitrile from an acetonitrile stream consisting of acetonitrile, 16 to 90 weight percent water, low boiling impurities having a boiling point below the boiling point of acetonitrile/wat...
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WO/2023/108601A1 |
A synthesis method for loxoprofen and analogues thereof as shown in the following reaction formula, wherein compound (I) undergoes a reaction under the catalysis of a catalyst to generate compound (II). The method avoids the use of a lar...
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WO/2023/105430A1 |
The present invention concerns processes for producing acrylonitrile from glycerol, comprising a dehydration step to produce acrolein and an ammoxidation step to produce acrylonitrile. The process comprises the recycling of one or more g...
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WO/2023/107345A1 |
A composition and method for dissolving foulant formed in a monomer manufacturing process. The composition may include an amide-containing compound and a solvent. Other components may optionally be included in the composition, such as a ...
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WO/2023/090086A1 |
Provided are a secondary monohydrofluoroalkane selective adduct and a method for producing the same. A compound represented by formula (3) is produced by means of a method including a step for reacting a compound represented by formula (...
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WO/2023/087503A1 |
Compound (3,5,5-trimethylcyclohex-2-enylidene)malononitrile reacts with different building blocks containing aldehyde groups to obtain four isophorone derivatives. The derivatives can mark mitochondria, lysosomes, endoplasmic reticula or...
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WO/2023/060929A1 |
The present invention relates to an application of a polydentate phosphite ligand in the catalytic synthesis of adiponitrile. The ligand is represented by general formula (I). A method for catalytically synthesizing adiponitrile comprise...
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WO/2023/064305A1 |
The present disclosure provides certain processes of making 3-fluoro-5-(((1S,2aR)-1,3,3,4,4-pentafluoro-2a-hydroxy-2,2a,
3,4-tetrahydro-1H-cyclopenta[cd]inden-7-yl)oxy)-benzonitrile
(Compound 1) and certain polymorphs thereof. Also prov...
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WO/2023/060458A1 |
The present disclosure provides certain processes ofmaking 3-fluoro-5- ( ( (1S, 2aR) -1, 3, 3, 4, 4-pentafluoro-2a-hydroxy-2, 2a, 3, 4-tetrahydro-1H-cyclopenta [cd] inden-7-yl) oxy) -benzonitrile (Compound 1) and certain polymorphs there...
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WO/2023/061999A1 |
The present invention discloses a distinct mode of action of a nickel catalyst to forge C-0 bonds to unlock the mild utilization of N2O as O-atom transfer reagent in the synthesis of complex phenols from the corresponding aryl halides.
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WO/2023/060811A1 |
Disclosed in the present invention are a fluralaner intermediate and a method for preparing fluralaner thereby. The fluralaner intermediate-5 is aaa. A synthetic route comprises: using m-xylene as a starting raw material, performing halo...
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WO/2023/047855A1 |
The present invention provides: a photosensitive composition which is not susceptible to an excessive decrease in the weight of components in the photosensitive composition or composition (in cases where the photosensitive composition or...
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WO/2023/044884A1 |
Disclosed is a method for synthesizing a diaryl ether by reacting a nickel/ketone double-catalyzed halogenated aromatic hydrocarbon with an arylphenol, comprising: under the protection of an inert gas, adding a halogenated aromatic hydro...
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WO/2023/040106A1 |
Disclosed in the present invention is a preparation method for an acetamide compound by means of green visible-light catalysis. In the method, LED lamps are used as light sources to provide energy, and economically available aromatic ami...
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WO/2023/040105A1 |
Disclosed is a preparation method for a green visible light-catalyzed acetate compound. In this method, an LED lamp is used as a light source to provide energy, economically available primary, secondary, and tertiary alcohols are used as...
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WO/2023/038411A1 |
An embodiment of the present invention provides a method for preparing a phthalonitrile-based compound, the method comprising the steps of: (a) adding a mixture including a phthalic acid-based compound and a nitrile-based compound into a...
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WO/2023/030279A1 |
Provided are a 3, 3-difluoroallylic onium salt as represented by formula (C), and a preparation method of the substance. Cheap industrial raw materials are used to prepare the important fluorine-containing reagent, which can be used as a...
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WO/2023/024532A1 |
Disclosed in the present invention is a one-step method for preparing a C-N coupling product using nitroaromatic hydrocarbon and alkyl or phenylboronic acid. The method comprises: adding nitroaromatic hydrocarbon, alkyl or phenylboronic ...
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WO/2023/015184A1 |
Provided herein is a process for the preparation of (R)-N-(5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden
-1-yl)-1-methyl-1H-pyrazole-4-carboxamide, intermediates thereof, and salts of the foregoing.
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WO/2023/003058A1 |
Provided in one embodiment is a method for preparing a phthalonitrile-based compound, comprising the steps of: (a) preparing a mixture comprising a phthalic acid-based compound and a nitrile-based compound; and (b) reacting the mixture, ...
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WO/2023/283831A1 |
Disclosed in the present invention is a compound having an inhibitory effect on a virus main protease (3CL protease, Mpro), which also has a significant inhibitory activity on the Mpros of SARS coronavirus (SARS-CoV) and novel coronaviru...
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WO/2023/280638A1 |
The application relates to vinyl thianthrenium compounds Vinyl- TT+X" of the Formula (I), a process for preparing the same and the use thereof for vinylating organic compounds.
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WO/2023/278688A1 |
Reaction pathways and conditions for the production of nitrogen-containing chelators, such as a glycine derivative, with reduction of ammonia byproducts. In particular, the present disclosure describes a process for the production of a n...
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WO/2022/243099A1 |
A process for preparing substituted biphenyls of the formula (I) which comprises reacting a compound of the formula (Il) in the presence of a base and of a palladium catalyst, with an organoboron compound of the formula (IV).
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WO/2022/230656A1 |
Provided is a method for producing a methyl-added compound, the method comprising a step for methylating a dinitrile compound represented by formula (1) in the presence of potassium carbonate and dimethyl carbonate to obtain the methyl-a...
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WO/2022/231697A1 |
An aspect of the present disclosure is a method that includes a first reacting a molecule from at least one of a carboxylic acid, an ester of a carboxylic acid, and/or an anhydride with ammonia to form a nitrile, where the first reacting...
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WO/2022/223678A2 |
Use of a compound of Formula 1 in a non-aqueous battery electrolyte formulation: wherein: R is an optionally fluorinated alky group, conveniently C1-6; each Y is independently H or F. X is H; a halogen, conveniently F; or an alkyl or a f...
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WO/2022/218733A1 |
The present invention provides a process for producing a substituted enamine compound of formula (I), and a process for producing oxazole compounds from the compound of formula (I). According to the processes of the present invention, it...
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WO/2022/219870A1 |
Provided is a platinum group metal supported catalyst column through which a reaction of forming a carbon-carbon bond in an aromatic bromide can be carried out at high yield. In the platinum group metal supported catalyst column, a plati...
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WO/2022/219953A1 |
The purpose of the present invention is to provide: an ion exchanger which shows small shrinkage upon the contact with an organic solvent in a water-wetted state; and a method for producing the ion exchanger. Provided is an ion exchanger...
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WO/2022/218734A1 |
The present invention provides a substituted enamine compound of formula (I), and a process for producing oxazole compounds from the compound of formula (I). According to the processes of the present invention, it can produce substituted...
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WO/2022/213997A1 |
Disclosed are a compound comprising a structural unit as represented by at least one of formulae (1)-(4). The compound comprises an alcohol-soluble or water-soluble group. The compound has a large molar extinction coefficient, a color co...
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WO/2022/214068A1 |
A heat removal pipe group, a fluidized-bed reactor (1) provided with the heat removal pipe group, a method for using the heat removal pipe group to control the temperature of the fluidized-bed reactor (1), and a method for fabricating un...
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WO/2022/214067A1 |
A cooling coil set, a method for increasing reaction load using the cooling coil set, and an application thereof in preparation of an unsaturated nitrile. The cooling coil set comprises ten cooling coils, and among at least one cooling c...
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WO/2022/214069A1 |
A heat removal pipe group, a method for controlling the reaction temperature by using the heat removal pipe group, and a method for fabricating unsaturated nitriles. The heat removal pipe group comprises at least one first heat removal p...
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WO/2022/205574A1 |
The present invention relates to a method for producing entacapone tablets, comprising: auxiliary material sieving, batching, mixing, sieving, mixing, dry granulation, sieving, mixing with magnesium stearate, and pressing into a tablet f...
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WO/2022/187848A1 |
The present invention relates to a curable cyanoacrylate composition comprising (i) at least one cyanoacrylate monomer, and (ii) at least one free radical stabilizer, wherein the free radical stabilizer is non-hazardous and shows good co...
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