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JP6732008B2 |
The present invention provides oxalic amide ligands and uses thereof in copper-catalyzed coupling reaction of aryl halides. Specifically, the present invention provides a use of a compound represented by formula I, wherein definitions of...
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JP6724780B2 |
The present invention provides a polythiol composition containing, as the main component, a polythiol compound (a) having two or more mercapto groups, and containing 0.5% by mass or less of a nitrogen-containing compound (b) in which at ...
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JP6713256B2 |
To provide a manufacturing method capable of effectively manufacturing a primary or secondary amine compound having a (poly)alkylene glycol chain with reducing the waste of raw materials by suppressing amount of unreacted raw materials c...
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JP6713112B2 |
The invention relates to a compound and a production method thereof, and provides a compound providing a photosensitive composition with excellent sensitivity and a manufacturing method of the compound. The method comprises introducing, ...
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JP6698557B2 |
The present invention relates to a method for preparing dimethyl disulphide, in batches or continuously, preferably continuously, said method including at least the following steps: a) reacting at least one hydrocarbon feedstock in the p...
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JP2020514339A |
The present invention relates to a method for catalytic aryl transfer to translocate the scaffold of an aromatic CX bond.
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JP2020513406A |
The present invention has the formula (I).[During the ceremony, R1, R2, X, A1, M and Z1Is the same as that defined in claim 1], the manufacture thereof, its use as a component in a liquid crystal medium, and an electro-optical display el...
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JP6690887B2 |
A production method in which a mercaptophenol compound is obtained using an industrially preferred sulfur atom introduction reaction, and intermediate compounds of the mercaptophenol compound are provided. A method for producing a mercap...
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JP6691557B2 |
The present invention provides a process for purifying methionine. A methionine product having a purity of up to 99% or higher is obtained by separating methionine from a salt by-product through a process comprising adsorption and desorp...
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JP2020059676A |
To provide a compound having a dibareran skeleton and a method for manufacturing the compound.There is provided a compound represented by the following general formula (I), where Rto Rrepresent each independently a hydrogen atom, an alky...
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JP6668508B2 |
The present invention discloses a terpinenol compound as well as its preparation method and use; structure of such terpinenol compound is as shown in Formula (I) or (II); in Formula (I), R is independently selected from C 12 ¼C 16 alk...
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JP6660518B1 |
Equation (1): [Chemical 1](In the formula, X1Indicates a halogen atom selected from the group consisting of a fluorine atom, a chlorine atom, a bromine atom, and an iodine atom, and n indicates an integer in the range of 1 to 10. ) A met...
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JP6656639B2 |
The purpose of the present invention is to provide: a novel compound which can generate a base and radical upon the irradiation with an active energy ray; a photopolymerization initiator which comprises the novel compound; and a photosen...
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JP2020505355A |
Regarding the crystal form of GFT-505, its manufacturing method, and its use. The crystalline forms CS1, CS2, CS5 and CS6 of GFT-505 according to the present invention have high purity, good stability, low hygroscopicity, good solubility...
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JP2020026412A |
To provide a production method capable of realizing a polythiol compound of interest with high yields efficiently and inexpensively in a simple manner.There is provided a method for producing at least one polythiol compound comprising a ...
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JP6647865B2 |
The invention relates to the use of a compound of formula (I) or a salt thereof for combating animal pests, where the symbols and indices are defined in the specification.
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JP2020504103A |
The present invention is suitable for kit formulation of highly sensitive and heat sensitive targeting molecules under mild reaction conditions [99mRegarding labeling procedures for incorporation into Tc (N) (PNP)] compounds. [Selection ...
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JP6633990B2 |
Provided is a method for producing a polythiol compound, including obtaining one or more polythiol compounds selected from the group consisting of a polythiol compound represented by Formula (3), a polythiol compound represented by Formu...
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JP6632493B2 |
Provided is a method for producing a polythiol compound, including reacting 2-mercaptoethanol with an epihalohydrin, wherein the reaction is carried out in the presence of a halide selected from the group consisting of a 2,3-dihalogeno-1...
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JP6620142B2 |
A method of making CF3CH2SH, comprising a step of reacting CF3CH2X, wherein X is halide or tosylate, with MSH, where M is an alkali metal such as Na or K, to yield CF3CH2SH.
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JP6619348B2 |
In one embodiment, the present application discloses compounds that are selective neuroactive agents for the treatment of diseases of the central nervous system (CNS). In one aspect, the neuroactive agents are NCDs of metal chelates, inc...
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JP6614699B2 |
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JP2019199431A |
To provide a method for producing isocyanate that suppresses a side reaction and continuously produces isocyanate.The present invention provides a method for producing isocyanate by pyrolysis of carbamate, the method including: a pyrolys...
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JP2019182800A |
To provide a manufacturing method of a fluorine-containing methylthio substituted compound using a novel fluorine-containing methylthio group introduction agent.A fluorine-containing methylthio introduction agent consisting of a bis(fluo...
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JP6594982B2 |
An antioxidative stabilizer has the following structure A, wherein R1 is a connection chain and the connection chain is a fatty chain, an aromatic structural chain or a hybrid chain of fatty and aromatic structures; R2 is B; X is O, S, N...
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JP2019178084A |
To provide an ingredient organic chloro compound and a (poly)thiol compound production method that are capable of realizing a (poly)thiol compound of interest with high yields efficiently and inexpensively in a simple manner.The (poly)th...
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JP2019178081A |
To provide: a thiol compound production method which allows selective production of a thiol compound of interest, inhibits production of by-products ending up wastes, is excellent in production efficiency, and can reduce production costs...
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JP2019178085A |
To provide a production method capable of realizing a (poly)thiol compound of interest with high yields efficiently and inexpensively in a simple manner.The (poly)thiol compound production method comprises reacting hydrogen sulfide with ...
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JP6588639B2 |
Provided is a method for producing a polythiol compound, the method including: step 1 of reacting 2-mercaptoethanol having a water content of 3000 ppm or less on a mass basis, with epihalohydrin to obtain a halide represented by the form...
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JP2019167316A |
To provide a separation method capable of effectively separating a desired sulfur compound together with desired hydrocarbon.There is provided a separation method of hydrocarbon and a sulfur-containing organic compound for contacting a m...
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JP6579585B2 |
The resulting polymer has an improved ability of recovering its original shape after release from deforming compression forces and improved tendency to recover during the application of those forces.
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JP2019156773A |
To provide a method for easily manufacturing a difluoromethyl substituted compound using inexpensive agents.There is provided a manufacturing method of a difluoromethyl substituted compound using difluoro iodomethane and a catalyst, in w...
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JP6578275B2 |
The present invention relates to a process for labeling compounds comprising thiol moieties with 3-arylpropiolonitrile compounds, to 3-arylpropiolonitrile compounds substituted with tag moieties and to specific 3-arylpropiolonitrile link...
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JP6578116B2 |
To provide a method of efficiently producing monosubstituted(fluoroalkyl)ethylenes.The method comprises reacting a 1-chloro-2-(fluoroalkyl)ethylene with an organoboron compound under coexistence of an alkylphosphine coordinated palladium...
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JP2019137693A |
To provide a method for producing, with a high yield, a fluorinated organic compound, the fluorinated organic compound having not been produced with a sufficient yield by a conventional method for producing a fluorinated organic compound...
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JP2019523256A |
The present invention relates to a novel vortioxatin analog represented by the following general formula (I), a polymorph or solvate thereof, a composition and a kit containing the analog, the polyform or solvate, the analog compound, an...
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JP6563921B2 |
The invention relates to the manufacture of certain polyunsaturated compounds employing a particular application of the Mitsonobu reaction in the presence of at least one anti-oxidant. We have found a method of making a pharmaceutically-...
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JPWO2018070543A1 |
An object of the present invention is to provide a method for producing phosphoramidite suitable for the production (synthesis) of nucleic acid more efficiently and with high purity. Efficient nucleic acid synthesis using a coupling reac...
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JP6543330B2 |
Methods for preparing the following compound are disclosed.
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JP6538711B2 |
The present invention refers to an amorphous form of a thiocolchicine derivative, IDN 5404, to a process for producing it and to pharmaceutical compositions thereof. The amorphous form is characterised by the XRPD pattern, DSC profile an...
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JP6526005B2 |
The present invention relates to a process for the preparation of bis-(2-hydroxyethyl)-disulfide by oxidizing 2-mercaptoethanol with oxygen in a reaction mixture comprising at least one homogeneously distributed iron comprising salt or c...
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JP6518810B2 |
Disclosed is to prevent generation of byproducts or a deterioration in the physical properties of a polythiol composition that may be caused by active oxygen during storage thereof by way of controlling the content of active oxygen in th...
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JPWO2017209297A1 |
In the presence of palladium catalyst and base, general formula (2):[During the ceremony, R1And R2Is the same as above. X represents a halogen atom. ], A triallylen compound can be synthesized under mild conditions using an easily availa...
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JP2019055921A |
To provide a method of efficiently and easily producing a stereoisomer from various amino compounds in spite of a scale of a system.The method of producing a stereoisomer includes the followings (1) and (2): (1) reacting a substance cont...
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JP2019052091A |
To provide an industrially advantageous production method for an optically active amide carboxylic acid derivative which is an important intermediate of a depsipeptide compound, which is expected as a novel, excellent molecular target an...
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JP6494240B2 |
and to methods of synthesizing and purifying calicheamicin derivatives.
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JP6493410B2 |
To provide a method for producing methionine, which comprises the step of contacting 2-amino-4-(methylthio)butanenitrile and water with each other in the presence of an oxide catalyst containing cerium. It is possible to use, as 2-amino-...
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JP2019048840A |
To provide a dimethyl disulfide synthetic method which is environmental friendly, and has low ecological toxicity, safety and high yield.A method includes: a) a process for reacting at least one kind of hydrocarbon supply material in the...
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JP6490079B2 |
The invention relates to a method for crystallizing D,L-methionine from aqueous solutions and/or suspensions containing D,L-methionine and D,L-methionine ammonium salts, having a Met content of 70-180 g/kg, an NH4+ content of 1-5 g/kg, i...
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JP6485878B2 |
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