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Matches 1 - 50 out of 1,392

Document Document Title
WO/2022/153003A1
The present invention relates to the field of perfumes and flavourings. More particularly, it relates to valencene derivatives and the use thereof as a perfuming or flavouring agent. It also relates to a perfuming or flavouring compositi...  
WO/2015/136292A9
The invention relates to a DDX3X inhibitorfor use in the treatment of pneumovirus infection in a mammal, wherein the DDX3X inhibitor may be a compound of Formula (I) wherein y, Z, R1, X, L, Ra and Rb are as defined herein. The invention ...  
WO/2022/065802A1
A polythiol composition according to exemplified embodiments comprises a first polythiol compound, and a second polythiol compound having a larger molecular weight than the first polythiol compound and having a number of functional group...  
WO/2022/029358A1
The present invention relates to a compound 1 or 2 or a composition comprising same. The invention also relates to a method for obtaining compound 1 or 2, and to the use of the compounds to detect GHB in beverages. The invention also inc...  
WO/2021/255279A1
The invention relates to novel compounds of formulae (I') and (II') for the treatment, alleviation or prevention of diseases, disorders and abnormalities which are responsive to the modulation or inhibition of the activation of a compone...  
WO/2021/175822A1
Compounds of formula (I), wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts, stereoisomers, enantiomers, tautomers and/or N-oxides of those compounds, can be used as pesticides.  
WO/2021/165187A1
The invention relates to a process for preparing 2-(phenylimino)-3-alkyl-1,3-thiazolidin-4-ones of the general formula (I), wherein Y1, Y2, R1, R2 and R3 have the meanings indicated in the description.  
WO/2021/162096A1
The present invention relates to a method for producing 4-(2-fluoro-4-(3-(2-phenylacetyl)thioureido)phenoxy)-7-metho xy-N-methylquinoline-6-carboxamide, the method comprising a step for linking 4-(4-amino-2-fluorophenoxy)-7-methoxy-N-met...  
WO/2021/162097A1
The present invention relates to: 4-hydroxy-7-methoxy-N-methylquinoline-6-carboxamide, 7-methoxy-N-methy-4-(4-(3-(2-phenylacetyl)thioureido)phenoxy )quinoline-6-carboxamide, 4-(2-fluoro-4-(2-phenylacetamide)phenoxy)-7-methoxy-N-methyl qu...  
WO/2021/136431A1
Disclosed is a series of benzo[d][1,2,3]triazole ether compounds, and specifically disclosed are a compound shown in formula (I) and pharmaceutically acceptable salts thereof.  
WO/2021/107478A1
The present invention relates to a method for preparing 1-(4-benzyloxy-benzyl)-3-methyl-thiourea and a method for preparing a novel stable crystalline form A of 1-(4-benzyloxy-benzyl)-3-methyl-thiourea.  
WO/2021/107476A1
The present invention relates to a 1-(4-benzyloxy-benzyl)-3-methyl-thiourea compound in crystalline forms A, B, C, or amorphous form, a method for preparing the compound in the crystalline or amorphous forms, and a use of the compound fo...  
WO/2021/102266A1
Di alkenyl succinic amide acids and processes for making and using same. The di alkenyl succinic amide acid can have a chemical formula of (I): where R1 and R2 can independently be a linear or branched C8 to C24 alkenyl group, Z1, Z2, Z3...  
WO/2021/073131A1
Provided in the present invention are a medicament for effectively killing drug-resistant disease bacteria and an application thereof in inhibiting drug-resistant disease bacteria. Specifically, provided in the present invention is a com...  
WO/2020/109506A1
The invention relates to compounds of formula (I) as follows: (I) wherein X1 and X2, identical or different, are NR5or a sulfur atom, Y is a group (C1-C10)alkanediyl, Ar1 and Ar2, identical or different, are an aryl group optionally subs...  
WO/2020/071961A1
The invention relates to an agent for the targeted therapy of solid malignant tumours which contains as active ingredient dichloroacetate 1-isobutanoyl-2-isopropyl isothiourea having the structural formula shown. Said agent exhibits a co...  
WO/2020/061367A1
The disclosure features novel lipids and compositions involving the same. Nanoparticle compositions include a novel lipid as well as additional lipids such as phospholipids, structural lipids, and PEG lipids. Nanoparticle compositions fu...  
WO/2020/047668A1
Provided herein are Myc-Max inhibitory compounds having the structure of Formula (I) and compositions thereof for use in the treatment of cancer. In particular, the Myc-Max inhibitory compounds may be useful for the treatment of cancers ...  
WO/2020/010143A1
In one aspect, compounds of Formula AA, or a pharmaceutically acceptable salt thereof, are featured: or a pharmaceutically acceptable salt thereof, wherein the variables shown in Formula A can be as defined anywhere herein, useful to tre...  
WO/2019/243414A1
The present invention relates to soluble epoxide hydrolase (sEH) inhibitors of formula (I) to processes for their obtention and to their therapeutic indications.  
WO/2019/189762A1
Provided is a method for manufacturing a polythiol compound, including reacting thiourea having an ammonium thiocyanate content of 0.05% by mass and a polyol compound, and obtaining an isothiuronium salt.  
WO/2019/179436A1
The present invention relates to the field of pharmaceutical chemistry. Disclosed are an acid amide compound and use thereof in the treatment of cancers. Disclosed is use of an acid amide compound represented by formula (I), or its cryst...  
WO/2019/160798A1
Accelerator solutions containing transition metal complexes based on organic ligands having one or more S-C-N, S-C-C-N, or S-C(=S)-S moieties are useful for accelerating the peroxide cure of resins such as unsaturated polyester resins.  
WO/2019/078246A1
Provided is a compound represented by formula (I) or a pharmaceutically acceptable salt thereof, which is useful as an IDO/TDO inhibitor. The compound represented by formula (I) or a pharmaceutically acceptable salt thereof can, for exam...  
WO/2018/227300A1
Novel urea, thiourea and squaramide compounds and bioisosteres thereof of formulas (I) and (VI) and the use thereof for treating, attenuating, inhibiting or preventing inflammation and inflammation-related pathologies are described herein.  
WO/2018/219309A1
The present invention relates to a vinylarene derivative which modulates or inhibits the enzymatic activity of indoleamine 2,3-dioxygenase 1 (IDO-1), and the use thereof, and further relates to a vinylarene derivative and the use thereof...  
WO/2018/172783A1
There is described a method of reducing polymer tar build-up in the production of methyl methacrylate and/or methacrylic acid by the acetone cyanohydrin process. In the method a stabiliser is contacted with the amide stage reaction mediu...  
WO/2018/170306A1
The disclosure features novel lipids and compositions involving the same. Nanoparticle compositions include a novel lipid as well as additional lipids such as phospholipids, structural lipids, and PEG lipids. Nanoparticle compositions fu...  
WO/2018/133756A1
The present invention relates to a targeted autophagy agonist and an application thereof in the treatment of neurodegenerative diseases, pertaining to the technical field of pharmaceuticals for the treatment of neurodegenerative diseases...  
WO/2017/168419A9
Disclosed methyl styrene farmin compounds, and crosslinked polymeric backbones comprising same. Further disclosed microsized and nanosized polymeric particles comprising polyisothiouronium methylstyrene (PITMS) and/or poly(methyl styrene...  
WO/2018/042460A1
The present invention discloses sulphur functionalized polyurea composite of Formula (I) and Formula (II) that provides an insoluble solid support for effective removal of metal residues from solvent streams and other reservoirs and to t...  
WO/2018/028665A1
Provided is a method for preparing an intermediate of 6-arylaminopyridonecarboxamide compound as an MEK inhibitor, comprising preparing a compound of formula (III) as an intermediate of 6-arylaminopyridonecarboxamide compound using a com...  
WO/2017/170826A1
The purpose of the invention is to provide a compound useful in the prevention or treatment of diabetes, obesity, and conditions related thereto. The present invention relates to an enhancing agent for glucagon-like peptide-1 receptor ac...  
WO/2017/099237A1
A compound represented by formula (I) and having a property of modulating the activity of an androgen receptor, or a pharmaceutically acceptable salt of the compound. X represents S or O; Z represents (Ra)n-A-(CR13R14)0-1-(CR11R12)0-1-; ...  
WO/2017/096430A1
The present invention relates to hydroxamic acid-based compounds, their intermediates, preparation and uses. The compounds are useful in imaging, particularly for the imaging of tumours and cancer, and especially for the imaging of prost...  
WO/2017/047572A1
A heat-sensitive recording material obtained by forming a heat-sensitive recording layer, which contains a basic dye and a developer, on a supporting body. The developer is composed of at least one N-substituted amino acid derivative rep...  
WO/2016/207726A1
The present description provides oligourea catalysts, a polar helical oligomeric strands, and methods for catalyzing reactions with polar helical oligomeric strands and oligourea catalysts. In particular, the invention relates to a polar...  
WO/2016/193284A1
The present invention relates to compounds of formula (I) as defined herein, to processes for preparing them, to pesticidal, in particular insecticidal, acaricidal, molluscicidal and nematicidal compositions comprising them and to method...  
WO/2016/184561A1
Novel inhibitors of the enzyme autotaxin are described. The inhibitors contain one or two zinc-binding groups at the appropriate distance, Also described are uses thereof, such as for the inhibition of autotaxin activity and the treatmen...  
WO/2016/128924A1
The present invention relates to a new chemical synthesis, intermediates and catalysts useful for the preparation of the neprilysin (NEP) inhibitor sacubitril. It further relates to new intermediate compounds and their use for said new c...  
WO/2016/079327A1
The invention relates to hydrosoluble hydroxybisphosphonic derivatives of doxorubicin of formula (I) and the pharmaceutically acceptable salts thereof. The invention also relates to the use of said compounds as a drug, especially in the ...  
WO/2016/062585A1
The present invention relates to a compound of formula (I) wherein: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 and G are as defined herein; and wherein the compound of formula (I) is optionally present as an agrochemically acce...  
WO/2016/040226A1
In its many embodiments, the present invention provides certain C-6 spirocarbocyclic iminothiadiazine compounds, including compounds Formula (I): or a tautomer thereof, and pharmaceutically acceptable salts of said compounds and said tau...  
WO/2015/157242A1
Lysophosphatidic acid acyltransferase-beta (LPAAT-β) catalyzes the production of phosphatidic acid (PA) from lysophosphatidic acid (LPA). The lipid cofactor PA contributes to the activation of c-Raf, BRAF, mTOR and PKC-ζ. LPAAT-β expr...  
WO/2015/090209A1
Provided in the present invention are a general formula I compound, the isomers, pharmaceutically-acceptable salt or solvate thereof, and application thereof to manufacturing medicine for preventing and/or treating drug-resistant tumours...  
WO/2015/054960A1
Provided are a novel Lesinurad intermediate, providing a synthetic process more economical, more efficient, safer, more environmentally friendly, and suitable for large-scale industrial production for the preparation of Lesinurad. Also p...  
WO/2015/030085A1
A photosensitive layer comprises: a phthalocyanine crystal in which a urea compound is contained. The urea compound has one or more urea moieties comprising: a carbonyl group, or a thiocarbonyl group, and two nitrogen atoms. Each of the ...  
WO/2014/158654A1
Compounds of formula (II): wherein A, R1, R2, R5 and R13 are described herein, or a stereoisomer, enantiomer or tautomer thereof or mixtures thereof, or a pharmaceutically acceptable salt or solvate thereof, are described herein, as well...  
WO/2014/143561A1
Compounds of formula (I): where R1, R2, R3, R4a, R4b, R5, R6 and R7 are defined herein, or stereoisomers or pharmaceutically acceptable salts thereof, are described herein. Such compounds have activity as SHIP1 modulators, and thus may b...  
WO/2014/087431A1
The present invention disclose an improved one pot process for synthesis of acyl thioureas of formula (I), with yield greater than 80%, from aroyl chlorides of formula (I) wherein, R' is an aryl or a heteroarylene group substituted with ...  

Matches 1 - 50 out of 1,392