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WO/2021/182594A1 |
The purpose of the present invention is to provide an easy method for producing hydroxylated chalcones and flavanones. The present invention relates to a method for producing hydroxylated chalcones and flavanones, the method being char...
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WO/2021/183431A1 |
Disclosed herein, inter alia, are compounds for binding FEMIB protein and uses thereof. In an aspect, provided herein is a pharmaceutical composition including a compound as described herein and a pharmaceutically acceptable excipient.
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WO/2021/182896A1 |
The present invention relates to isoliquiritigenin derivatives, and a use thereof. The isoliquiritigenin derivatives induce brown fat differentiation and do not have significant cytotoxicity. A composition, which is for inducing brown fa...
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WO/2021/175029A1 |
A crystalline modification I of (3-bromo-6-methoxy-2-methylphenyl) (2, 3, 4-trimethoxy-6-methylphenyl) methanone (metrafenone) is provided. A method of preparing the crystalline modification I, a composition comprising the crystalline mo...
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WO/2021/178850A1 |
The disclosure relates to a method of making at least one serrulatane comprising contacting a terpene or a terpenoid substrate with at least one of a cis-prenyl transferase, a terpene synthase, and a cytochrome P45Q. The disclosure also ...
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WO/2021/176009A1 |
The present invention relates to the field of organic synthesis and more specifically it concerns a process for preparing compound of formula (I) by a cross metathesis reaction. Said compound of formula (I) is valuable new chemical inter...
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WO/2021/171301A1 |
A process for preparation of 3-Trifluoromethyl acetophenone oxime of formula I comprising the steps of: a) Reacting an isomeric mixture of halo benzotrifluoride with Mg metal in an organic solvent in presence of a catalyst to obtain a Gr...
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WO/2021/167008A1 |
This method for producing an aromatic astatine compound comprises reacting aromatic iodonium ylide with astatine to produce an aromatic astatine compound.
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WO/2021/160139A1 |
A 9,10-dihydrophenanthrene compound and use thereof in the treatment of liver injury. Specifically, a compound of formula (I) or a compound of formula (II) is provided, which exhibits anti-inflammatory and antioxidant activities in liver...
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WO/2021/156214A1 |
The present invention relates to a Fries rearrangement of specific dimethylphenylacylates to form the desired respective hydroxyaryl ketones having two methyl groups bound to the aromatic ring. It has been found that the process is surpr...
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WO/2021/158046A1 |
The present invention relates to a pharmaceutical composition comprising gossypol or a derivative thereof as an active ingredient for prevention or treatment of a neurological disorder. A decrease in the level of the inhibitory neurotran...
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WO/2021/149900A1 |
The present invention relates to: a disubstituted adamantyl derivative or a pharmaceutically acceptable salt thereof, and an anticancer pharmaceutical composition and a kit containing same as an active ingredient. The disubstituted adama...
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WO/2021/149801A1 |
This fullerene derivative has a structure represented by formula (1) or formula (2) (wherein Ar represents a substituted or unsubstituted aromatic ring, * represents a carbon atom at a linkage point with respect to a fullerene core, X re...
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WO/2021/120767A1 |
The present application provides belt[n]arene[n]tropilidene, a belt[4]arene[4]tropylium compound, a belt[4]arene[4-m]tropilidene[m]dicarbonyl compound, a belt[4]arene[4-m]tropilidene[m]benzotropilidene compound, a belt[4]arene[4-m]benzot...
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WO/2021/122955A1 |
The invention concerns a method for preparing a mixture containing cyclohexanol and cyclohexanone, comprising the step of hydrogenating cyclohexyl hydroperoxide in cyclohexane in the presence of a Raney nickel catalyst to give cyclohexan...
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WO/2021/108999A1 |
Disclosed is a method for the continuous synthesis of 4-ethoxy-1,1,1-trifluoro-3-buten-2-one. The continuous synthesis method comprises: continuously introducing a raw material comprising vinyl ethyl ether, triethylamine and trifluoroace...
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WO/2021/110680A1 |
The present invention relates to compounds of formula (I) as properfume compounds. In particular, the present invention relates to a method to release a compound being a carbonyl of formula (II), a formate ester of formula (III) and/or a...
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WO/2021/103795A1 |
Provided by the present disclosure are an oxidized ring belt [8] aromatic hydrocarbon derivative and a preparation method therefor. The oxidized ring belt [8] aromatic hydrocarbon derivative is a compound represented by formula (A) or a ...
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WO/2021/099577A1 |
The present invention relates to a method for preparing a macromolecular composition comprising phenylglyoxaldehyde-derivatives. The invention also relates to the macromolecular compositions per se, and to methods of using the macromolec...
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WO/2021/102361A1 |
Disclosed herein, inter alia, are compounds and methods for inhibiting Caspase 6 and the treatment of diseases, pharmaceutical composition including a compound as described herein and a pharmaceutically acceptable excipient and methods o...
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WO/2021/098319A1 |
Disclosed in the present invention are a class of 6-benzylidene-2-aryl ethynyl cyclohexenone derivatives and pharmaceutically acceptable salts thereof, preparation methods therefor, pharmaceutical compositions containing these derivative...
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WO/2021/093636A1 |
Provided are a high-quality curcumin product, a production method therefor and an application thereof. The high-quality curcumin product has low solvent residue, good fluidity, and a high bulk density. The method for producing the produc...
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WO/2021/088495A1 |
Provided are a crystal form I of a curcumin derivative (C66), a preparation method therefor and an application thereof, which relate to the field of the medical and chemical industry. The crystal form I contains characteristic peaks meas...
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WO/2021/090910A1 |
A molecular structure altering agent which interacts specifically with protein aggregates and detects said protein aggregates, and a detection method of protein aggregates are provided. Further, a cleaning agent and a cleaning method are...
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WO/2021/086089A1 |
The present invention relates to a method for preparing 1,3-cyclopentanediol by adding a ruthenium catalyst, from which the surface oxide layer has been removed, to 4-hydroxy-2-cyclopentenone. The method is simple since 1,3-cyclopentaned...
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WO/2021/085966A1 |
The present invention relates to cyclododecanone and a preparation method therefor. According to the present invention, a cyclododecanone preparation method capable of achieving a high conversion rate and minimizing unreacted materials a...
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WO/2021/085916A1 |
The present invention relates to a method for preparing an astaxanthin monoester and, more specifically, to a method for preparing an astaxanthin monoester, comprising: step 1-1 of preparing a basic alcohol solution; step 1-2 of transest...
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WO/2021/085978A1 |
The present invention relates to cyclododecanone and a preparation method therefor, and according to the present invention, there may be provided a preparation method for cyclododecanone, the method capable of realizing a high conversion...
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WO/2021/079356A1 |
Disclosed herein are compounds and methods for promoting plant growth. Formulations containing one or more disclosed compounds or salts thereof, and one or more excipients are disclosed. The formulation adjuvant can be a solid carrier, a...
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WO/2021/077194A1 |
The present invention relates to the production of carbonyl compounds and derivatives, by means of high yield and purity syntheses, providing antitumour active principles with selective antiproliferative properties and antimestastatic ac...
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WO/2021/076945A1 |
Disclosed are a series of compounds or their tautomers having a general structure represented by Formula la or lb and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions comprising said compounds or ...
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WO/2021/076938A1 |
Disclosed are a series of compounds or their tautomers having a general structure represented by Formula (la), (lb), (Ila), (lIb), or (lIc) and pharmaceutically acceptable salts thereof. The present disclosure also relates to pharmaceuti...
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WO/2021/076771A1 |
The present invention discloses a composition comprising 70%-80% w/w tetrahydrocurcuminoids, 10%-20% w/w hexahydrocurcuminoids and 5%-10% w/w octahydrocurcuminoids and its therapeutic application. More specifically, the present invention...
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WO/2021/073456A1 |
Provided are a class of macrocyclic and cage-like molecules based on a biphenylarene and derivative compounds, a synthesis method therefor and the use thereof. A series of new macrocycles and molecular cages are obtained in a high yield ...
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WO/2021/070658A1 |
Provided is a method for producing a cyclopentane compound, the method allowing easy synthesis of a cyclopentane compound in a diastereoselective manner and, as necessary, in an enantioselective manner, the compound having multiple asymm...
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WO/2021/072181A1 |
Described are compositions and methods for inhibiting polymerization of a monomer (e.g., styrene) composition a quinone methide polymerization retarder and an ammonium salt. In a mixture, the ammonium salt improves the efficacy of the qu...
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WO/2021/068530A1 |
Disclosed is a Z-type solanone, the three-dimensional structural formula thereof being (I) or (II), and the name thereof being: (S,Z)-5-isopropyl-8-methyl-6,8-dien-2-one, or (R,Z)-5-isopropyl-8-methyl-6,8-dien-2-one. Also disclosed are a...
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WO/2021/068533A1 |
A drug for antagonizing the replication of porcine reproductive and respiratory syndrome virus (PRRSV) and an application thereof. By using a viral infection test, a drug which antagonizes PRRSV - xanthohumol - is discovered for the firs...
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WO/2021/062916A1 |
Provided is a method for catalytically synthesizing ketoisophorone using a perovskite-type composite oxide. The method involves subjecting α-isophorone, acting as a raw material, to a continuous oxidation reaction in a trickle bed react...
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WO/2021/060334A1 |
In the present invention, high-purity acetoin can be separated and recovered at a low cost, through a step A in which an acetoin-containing solution is filtered through a nanofiltration membrane, and the acetoin-containing solution is re...
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WO/2021/060276A1 |
Provided, inter alia, is a fluorinating agent that can selectively produce a monofluorination product through preferential synthesis of the monofluorination product over a difluorination product, in a fluorination reaction in which a flu...
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WO/2021/059287A1 |
A method of oxygenating a benzylic C-H bond is provided. The method comprises light induced activation of an initiator and subsequent reaction with oxygen, resulting in the formation of free radicals. Subsequently, free radicals catalyze...
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WO/2021/062030A1 |
This present disclosure relates to protein kinase C (PKC) modulating compounds, methods of treating a subject with cancer using the compounds, and combination treatments with a second therapeutic agent.
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WO/2021/056936A1 |
The present invention relates to the technical field of microbial pesticides, in particular to a polyketone compound having a trans-decalin ring and obtained from a solid fermentation product of the bacterial strain Penicillium sp. TR85 ...
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WO/2021/055271A1 |
Processes for converting a hydrocarbon reactant into an alcohol compound and/or a carbonyl compound are disclosed, and these processes include the steps of forming a supported chromium catalyst comprising chromium in a hexavalent oxidati...
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WO/2021/051168A1 |
The invention discussed in this application relates to hydroxamic acid-based compounds that are useful as imaging and therapeutic agents when bound to an appropriate metal centre, particularly for the imaging of tumours.
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WO/2021/055270A1 |
Processes for converting a hydrocarbon reactant into an alcohol compound and/or a carbonyl compound are disclosed, and these processes include the steps of irradiating the hydrocarbon reactant and a supported chromium catalyst comprising...
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WO/2021/038637A1 |
Provided are: a novel vitamin A derivative which is useful as a medicinal drug and a cosmetic and which comprises a compound represented by formula (I) or formula (II) (in the formulae, R1 and R2 each independently denote a hydrogen atom...
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WO/2021/035382A1 |
Provided is a method for the continuous synthesis of 2-cyclopenten-1-one. The continuous synthesis method comprises: loading a catalyst in a continuous reaction device, then continuously conveying cyclopentene, an oxidant and a solvent i...
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WO/2021/039558A1 |
The present invention addresses the problem of providing: a phenolic resin which has excellent flowability and gives cured objects having an excellent balance among high-temperature modulus, low hygroscopicity, and dielectric properties ...
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