Login| Sign Up| Help| Contact|

Patent Searching and Data


Matches 701 - 750 out of 3,725

Document Document Title
WO/2009/075080A1
Disclosed is a fluoroalkylsulfide derivative having excellent pest control activity or a salt thereof. Also disclosed is a pest control agent characterized by containing such a fluoroalkylsulfide derivative or a salt thereof as an active...  
WO/2009/074733A2
The invention relates to compounds of the formula (I) in which A is an angiotensine-converting enzyme inhibitor including at least one salifiable basic function, B is a compound including at least one acidic sailifiable function and at l...  
WO/2009/071577A1
Oxadiazole derivatives of formula (I) where ring A is a bicyclic or tricyclic system. Claimed compounds are active on nicotinic acetylcholine receptors (nAChRs), and are useful to treat neurological, psychiatric, and gastrointestinal dis...  
WO/2009/067797A1
Several parasites responsible for mammalian diseases are dependent on cysteine protease for various life-cycle functions. Inhibition or decreasing function of these proteases can be useful in the treatment and/or prevention of these para...  
WO/2009/067663A1
1,3-Dipole-functional compounds (e.g., azide functional compounds) can be reacted with certain alkynes in a cyclization reaction to form heterocyclic compounds. Useful alkynes (e.g., strained, cyclic alkynes) and methods of making such a...  
WO/2009/060278A1
The invention relates to compounds of formula (I) and to pharmaceutically acceptable salts, prodrugs, solvates or hydrates thereof. This invention also relates to a method of using such compounds in the treatment of hyperproliferative di...  
WO/2009/058552A1
The present invention provides a novel alpha-(N-sulfonamido)acetamide compound, its pharmaceutical composition, processes thereof and a method for the treatment of Alzheimer's disease and other conditions associated with β- amyloid pept...  
WO/2009/054923A2
The present invention relates to a process for producing crystalline 3-[(1S)-1-(1-{(S)-(4-chlorophenyl)[3-(5-oxo-4,5-dihydro-1,3, 4-oxadiazol-2-yl)phenyl]methyl} azetidin-3-yl)-2-fluoro-2-methylpropyl]-5-fluorobenzonitrile , and novel sa...  
WO/2009/054423A1
[PROBLEMS] To provide a compound which is useful as a medicinal agent having an agonistic activity on a GPR40 receptor, particularly an insulin secretion promoter or a prophylactic and/or therapeutic agent for diabetes. [MEANS FOR SOLVIN...  
WO/2009/049961A2
The present invention refers to new NO-donors aspirin derivatives, a process for their preparation and pharmaceutical compositions containing them.  
WO/2009/051718A2
The present invention relates generally to novel calcimimetic compounds and pharmaceutical compositions comprising them. The invention also relates to methods of treating of diseases or disorders related to the function of the calcium se...  
WO/2009/043890A1
The invention relates to compounds of formula (I): wherein R1, R2, Ra , Rb,Rc and W, have the meanings given in claim 1. The compounds are useful e.g. in the treatment of autoimmune disorders, such as multiple sclerosis.  
WO/2009/041972A1
Embodiments of the present invention provide novel antibactehals that target penicillin-binding proteins or other important cellular targets. Methods for inhibiting growth (reproduction, etc.) of bacteria using compounds described herein...  
WO/2009/040507A1
Compounds of formula (IA) or (IB) have antibacterial activity : wherein W is =C(H)- or =N-; R3 is a radical of formula -(Alk1)m-(Z1)p-(Alk2)n-Q wherein m, p and n are independently 0 or 1, provided that at least one of m, p and n is 1, Z...  
WO/2009/034396A2
Methods for overcoming multiple herbicide resistance (MHR) in plants using inhibitors of GST suppression of Formula (I), novel chemical inhibitors of Formula (Ia), compositions comprising compounds of Formula (I), and uses and methods re...  
WO/2009/023854A1
Compounds that have agonist activity at one or more of the SlP receptors are provided. The compounds are sphingosine analogs that, after phosphorylation, can behave as agonists at SlP receptors. Formula (I):  
WO/2009/008748A1
Pyrazolo[1,5-a]pyridines are described, including methods for their preparation, and their use as agents or drugs for cancer therapy, both alone or in combination with radiation and/or other anticancer drugs.  
WO/2009/004990A1
It is intended to provide a prostaglandin F2α receptor agonist (FP receptor agonist), which comprises a biphenyl derivative represented by the following general formula (I) (wherein m represents an integer of 0 to 2; n represents an int...  
WO/2009/005076A1
[PROBLEMS] To provide a compound useful as a therapeutic agent for chronic renal failure or diabetic nephropathy. [MEANS FOR SOLVING PROBLEMS] As a result of an intensive and extensive study on compounds having antagonistic activities on...  
WO/2008/157407A2
Compounds of formula (I) hat are inhibitors of transcription factors of leukemia cell lines are provided. In addition, pharmaceutical compositions including the inhibiting compounds and methods for treating leukemia are also provided.  
WO/2008/152149A1
The present invention relates to new compounds of formula (I) possessing agonistic activity at sphingosine-1 -phosphate (S1 P) receptors, their process of preparation and their use as immunosuppressive agents. The invention is also direc...  
WO/2008/135447A1
This invention relates to novel acetamide derivatives that are found to be potent modulators of ion channels, in particular potassium channels and chloride channels, and, as such, are valuable candidates for the treatment of diseases or ...  
WO/2008/129129A1
Fatty acid amide hydrolase inhibitors of the Formula (I) are provided, wherein R is a heterocyclic or heterocyclic carbonyl moiety and R' is a group consisting of H, substituted or unsubstituted alkyl, substituted or unsubstituted hetero...  
WO/2008/130370A1
Novel hydroxylated 1,2,4-oxadiazole benzoic acid compounds, methods of using and pharmaceutical compositions comprising a hydroxylated 1,2,4-oxadiazole benzoic acid derivative are disclosed. The methods include methods of treating or pre...  
WO/2008/129319A1
Sodium, magnesium, tert -butylammonium salt, tris( hydroxymethyl)methylammonium, triethanolammonium, diethanolammonium, ethanolammonium, methylethanolammonium, diethylammonium and nicotinamide salts of a compound of formula (I) are provi...  
WO/2008/124878A1
The present invention relates to non-steroidal compounds useful in the treatment of inflammatory conditions and pharmaceutical compositions comprising them. A representative example of these compounds is formula (III).  
WO/2008/123207A1
[PROBLEMS] To provide a compound useful as a therapeutic agent for chronic renal failure or diabetic neuropathy. [MEANS FOR SOLVING PROBLEMS] Disclosed is an ornithine derivative having an EP4 receptor antagonistic activity. In the compo...  
WO/2008/123349A1
Disclosed is an N-phenyl-N'-phenylsulfonylpiperazine derivative. Also disclosed is a method for efficiently producing an intermediate for the N-phenyl-N'-phenylsulfonylpiperazine derivative. Specifically disclosed is a method for produci...  
WO/2008/122787A1
The present invention relates to compounds of general formula (I): wherein A, Y, X, n and B are as defined herein; and their use in the treatment and prevention of metabolic disorders, inflammatory conditions, allergic conditions, fever,...  
WO/2008/119028A1
Alkenydiarylmethane compounds are described. Such compounds are a class of non-nucleoside inhibitors of HIV-I reverse transcriptase, which may also be used as part of a combination therapy to treat HIV infection. Compounds described here...  
WO/2008/115259A2
This invention describes compounds and pharmaceutical compositions useful as ubiquitin agent inhibitors, particularly ubiquitin ligase inhibitors. The compounds and pharmaceutical compositions of the invention are useful as inhibitors of...  
WO/2008/107501A1
The invention relates to a compound of general formula (I) for use in a pharmaceutical composition for treating infectious diseases caused by Helicobacter pylori. R1 and R2 are O, S or N, and can be identical or different; R3 is O or S; ...  
WO/2008/107677A2
A compound of formula (I) or a pharmaceutically acceptable salt or prodrug thereof: wherein X is an oxygen or sulphur atom A is CH(R6)-, -O- or NR7 or when A is NR7, then R1 and NR7 can together form a ring such that R1 and R7 are (CH2)n...  
WO/2008/105607A1
A novel heteroaryl-imidazole compound of formula (I) or a pharmaceutically acceptable salt thereof is effective as a cannabinoid CB1 receptor inverse agonist or antagonist, which is useful for preventing or treating obesity and obesity-r...  
WO/2008/096760A1
Disclosed is a label which can label a molecule readily (i.e., which has a high labeling reaction rate) and can provide a high reaction yield. Also disclosed is a precursor for the production of the label. Specifically disclosed are: a h...  
WO/2008/080511A1
The present invention relates to heteroarylcyclopropanecarboxamides of the formula (I), in which Het, X, Ra, Rb, Rc, Rd, R1, R2 and R3 have the meanings indicated in the claims, which modulate the transcription of endothelial nitric oxid...  
WO2008039431B1
The present invention relates to crystalline forms of 3- [5- (2 -fluorophenyl) - [l,2,4]oxadiazol-3-yl] -benzoic acid (formula (I)), pharmaceutical compositions and dosage forms comprising the crystalline forms, methods of making the cry...  
WO/2008/079836A2
The present invention relates generally to novel macrocycles of Formula (I) or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein the variables A, B, C, D, L, M, W, Z1, Z2, Z3, Z4, R1, R2,...  
WO/2008/077507A1
The present invention relates to heteroaryl-substituted carboxamides of the formula (I) in which Het, A, X, R1, R2 and R3 have the meanings indicated in the claims, which modulate the transcription of endothelial nitric oxide (NO) syntha...  
WO/2008/064320A2
Hydrindane analogs of formula (IA) and (IB) that have agonist activity at one or more of the SlP receptors are provided. The ' compounds are sphingosine analogs, which, after phosphorylation, can behave as agonists at SlP receptors.  
WO/2008/064315A1
Tetralin analogs that have agonist activity at one or more of the SlP receptors are provided. The compounds are sphingosine analogs, which, after phosphorylation, can behave as agonists at SlP receptors.  
WO/2008/059128A1
The present invention relates to new phenylic derivatives, wherein these products exhibit a good affinity for certain sub-types of cannabinoid receptors, in particular the CB2 receptors. They are of particular interest for treating patho...  
WO/2008/058178A1
The present invention is directed to modulators of indoleamine 2,3-dioxygenase (IDO), as well as pharmaceutical compositions containing the same and methods of use thereof related to the treatment of cancer and other diseases. Formula (I).  
WO/2008/057775A2
A compound of Formula I and enantiomers, diastereomers and pharmaceutically-acceptable salts thereof. Also disclosed are pharmaceutical compositions containing compounds of Formula I, and methods of treating conditions associated with th...  
WO/2008/050200A1
This invention relates to novel compounds of formula (I) wherein R1, R2, R3, R4, R5, G1, G2, Y, n, and Ar1 are as defined in the specification, pharmaceutical compositions containing said compounds useful as calcium channel antagonists, ...  
WO/2008/039023A1
A heteroaryl-pyrazole compound of formula (I) or a pharmaceutically acceptable salt thereof is effective as a cannabinoid CB1 receptor inverse agonist or antagonist, which is useful for preventing or treating obesity and obesity-related ...  
WO/2008/037476A1
Disclosed are polycyclic compounds of the following formula (I) and their use as anti-inflammatory and immunosuppressive agents.  
WO/2008/035239A1
The invention relates to phenyl derivatives of formula (I), their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.  
WO/2008/036652A2
The present invention is directed to amidino heterocyclic compounds of formula Ia and IIa which are modulators of indoleamine 2, 3 - dioxygenase (IDO), as well as compositions and pharmaceutical methods thereof.  
WO/2008/030570A1
Provided herein are processes for the preparation of compounds useful for the treatment, prevention or management of diseases associated with a nonsense mutation. More specifically, provided herein are processes for the synthesis of 1,2,...  

Matches 701 - 750 out of 3,725