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Matches 1 - 50 out of 3,612

Document Document Title
WO/2022/165838A1
Provided is a synthesis apparatus for synthesizing biomacromolecules. The synthesis apparatus is used for synthesizing biomacromolecules, and comprises a feeding apparatus, a recognition apparatus, a reaction apparatus, a sorting apparat...  
WO/2022/165803A1
A production apparatus and a production method for sucrose-6-ester, the apparatus comprising a tank, a rotary distillation device, and a condensing device, wherein the tank comprises a separation cavity and a reaction cavity, the condens...  
WO/2022/162018A1
The invention relates to processes for purification of poly-tagged products, such as mRNA, from synthetic or biological compositions. The process involves contacting the composition with a oligo d (T)-functionalized chromatography medium...  
WO/2022/165224A1
Broadly applicable and stereoselective formation of glycosidic linkage remains challenging yet of critical importance in giycoscience. By developing an SN2 glycosylation, this work advances a general solution to this challenge via stereo...  
WO/2022/155909A1
Provided are a production device and production method for sucrose-6-ester. The device comprises separators and a reactor; each separator comprises an accommodation cavity and a condensation cavity which are provided closely and in commu...  
WO/2022/156424A1
An amphiphilic molecular self-assembly nanodrug for tumor treatment, a preparation method therefor and a use thereof. Specifically disclosed is an amphiphilic compound, which is a conjugate of a hydrazine group-modified organic photother...  
WO/2022/156117A1
Disclosed is a method for modifying DNA with glycosidase and an oxylamine compound, comprising the following steps: performing solid-phase synthesis of a DNA chain having a non-canonical base; reacting the DNA chain having the non-canoni...  
WO/2022/155947A1
Production equipment and a production method for sucrose-6-ester, wherein the equipment comprises a housing, a film scraping device, and a base. The film scraping device is disposed on the base, and the housing covers the outer sides of ...  
WO/2022/157173A1
The present invention relates to methods of making a nicotinamide ribofuranoside salt, in particular a crystalline nicotinamide ribofuranoside salt, via salt metathesis comprising subjecting nicotinamide ribofuranoside hydrogen malate or...  
WO/2022/151978A1
Provided in the present invention is a pharmaceutically active ingredient extract extracted from Polygala japonica Houtt., which extract comprises a flavonol compound of the following formula (I) structure as a first active ingredient, a...  
WO/2022/140931A1
The present application provides a chlorination method for a sucrose-6-carboxylate, comprising: dissolving a solid phosgene into a first solvent to obtain a solid phosgene solution, and dissolving a sucrose-6-carboxylate into a second so...  
WO/2022/141229A1
A sucralose preparation method, a crude product solution, and sucralose, the method comprising: dissolving sucralose-6-ethyl ester in ethanol to form a sucralose-6-ethyl ester reaction solution; distilling the sucralose-6-ethyl ester rea...  
WO/2022/141228A1
A preparation method for sucralose, a crude product solution, and sucralose, the method comprising: dissolving a sucralose-6-acetate into methanol, adding calcium oxide into the reaction solution of the sucralose-6-acetate for a deacylat...  
WO/2022/144422A1
The present invention refers to a nucleic acid conjugate comprising at least one 2',3ยด-O ketal moiety. This conjugate is suitable for the target-specific or target-selective delivery of nucleic acid molecules into cells such as mammalia...  
WO/2022/141457A1
The present application provides a mono-tin organic compound which is used for synthesizing sucrose-6-carboxylate. The compound is a compound represented by formula (1) below. R1, R2 and R3 each independently represent C1-C8 linear or br...  
WO/2022/135173A1
Provided is an Escherichia coli strain, H03A2190830. The deposit number thereof is CCTCC NO: M2019900. Further provided are a method for producing a polysialic acid by means of using the Escherichia coli, and a method for producing a sia...  
WO/2022/138748A1
The present invention provides a labeling method that comprises a step for labeling a substrate, which has a carbon-hydrogen bond, with an oxygen isotope with use of a catalyst and an oxidant that is produced from a hypervalent iodine co...  
WO/2022/135319A1
The present invention relates to a method for the automatic preparation of a fondaparinux sodium pentasaccharide intermediate. The method is based on an automatic preparation device. According to the method, automatic preparation of thre...  
WO/2022/134385A1
The present invention relates to the technical field of agricultural chemicals and preparation. Specifically, disclosed is a purification method for 4"-(s)-methylamino abamectin B2a benzoate. The purification method comprises the followi...  
WO/2022/133205A1
The present invention relates to efficient synthetic processes useful in the preparation of antiviral nucleosides, particularly uridine 4-oxime 5'-(2-methylpropanoate) {(2R,3S,4R,5R)-3,4-dihydroxy-5-[4-(hydroxyimino)-2-oxo-3,4-d ihydropy...  
WO/2022/130322A1
The present invention concerns a method for separating different oligosaccharides having at least one carboxylic acid group, also referred to as charged oligosaccharides. The method allows for the high throughput separation of oligosacch...  
WO/2022/132694A1
A system for glucaric acid production, the system comprising: (a) a first input selected from the group consisting of glucuronolactone, a disaccharide feedstock, a cleaved starch, a disaccharide, glucuronic acid, or a combination thereof...  
WO/2022/130324A1
Disclosed herein are systems and methods for the purification of human milk oligosaccharides (HMOs). The HMOs can be purified from a suspension containing one or more of a bacterial biomass, cell fragments, small particles, and biomolecu...  
WO/2022/132681A1
A method and device for building an oligonucleotide on a solid phase resin within a filter reactor, wherein the method and device as used as a solid phase synthesis system. As part of the solid phase synthesis process, a protecting group...  
WO/2022/125068A1
A method of isolating a biological component from a biological sample can include dispensing a sample fluid including magnetizing particles and a wash buffer into interconnected volumes including a bulk fluid volume fluidically connected...  
WO/2022/125735A1
The disclosure provides processes for preparing the compound of formula (VIII) and pharmaceutically acceptable salts thereof. Intermediates useful in preparing the compound of formula (VIII) are also provided.  
WO/2022/122613A1
The invention provides the use of a compound of formula (I), as defined, for the preparation of an oligonucleotide comprising at least one phosphorodithioate internucleoside linkage. Various synthesis methods using compounds of formula (...  
WO/2022/117074A1
The present application relates to a method for preparing crystalline D-psicose. In the present application, crystalline D-psicose is prepared by means of combining an evaporative crystallization method and a cooling crystallization meth...  
WO/2022/110017A1
A method for purifying sucralose-6-ethyl ester, comprising: a preparation step: obtaining an ethyl acetate saturated solution of crude sucralose-6-ethyl ester heated to a predetermined temperature; a gradient crystallization step: perfor...  
WO/2022/110560A1
A porous resin used to solid phase synthesis and a preparation method therefor, specifically being a porous resin having functional groups being an amino group or a hydroxyl group and a preparation method therefor. Using an olefin compou...  
WO/2022/109171A1
The present invention relates to compositions and methods for the purification of ribonucleic acids including a polyA tail. The compositions and methods include a polystyrene divinylbenzene particle, a linker, and a poly-deoxythymidine o...  
WO/2022/107013A1
The present invention relates to a process for the synthesis of Fondaparinux pentasaccharide and its intermediates. Specifically, the present invention relates to a novel catalytic process for the synthesis of Fondaparinux pentasaccharid...  
WO/2022/103842A1
The present disclosure describes novel reagents and processes for preparing oligonucleotides, which have two or more nucleotides. In one embodiment, the reagent is represented by Formula I' or B.  
WO/2022/099606A1
A method for purifying sucralose, comprising: removing a solvent from a sucralose reaction liquid to obtain a concentrated solution of a sucralose crude product; under stirring, adding ethyl acetate to the concentrated solution of the su...  
WO/2022/094913A1
Disclosed are a sialic acid Neu5Ac derivative, and a preparation method therefor and the use thereof. The structure of the derivative is as shown in (VII)I below, wherein R1 is selected from hydroxyl, methoxy, or substituted methoxy; R2 ...  
WO/2022/096613A1
The present invention relates to a method for concentrating aqueous solutions of human milk oligosaccharides, in which an aqueous solution comprising at least one human milk oligosaccharide is subjected to a reverse osmosis process by me...  
WO/2022/099040A1
The present disclosure provides methods of anchoring active molecules on the surface of a cell, methods of anchoring at least two active molecules on the surface of a cell, and methods of enhancing an immune response to a target cell in ...  
WO/2022/089589A1
A flavonoid glycoside-organoamine DPP-4 inhibitor double salt. The flavonoid glycoside has the structural formula as shown in formula (1), wherein R1-R9 are independently selected from a group consisting of -H, -OH, C1-C6 alkyl, alkoxy o...  
WO/2022/089593A1
The present application relates to the technical field of pharmaceutical chemistry, and in particular relates to a double salt compound of a flavone glycoside-organic amine anti-tumor agent, a preparation method therefor and the use ther...  
WO/2022/089600A1
The present application relates to a double salt compound of flavonoid glycoside and an organic amine antimicrobial agent. The flavonoid glycoside has a structural general formula represented by the following formula (1), wherein R1-R9 a...  
WO/2022/090450A1
The present invention relates to a process for the purification of an acidic human milk oligosaccharide (HMO) from a fermentation broth using ion exchange methods. This process allows for a reduction of the number and/or extent of desalt...  
WO/2022/089598A1
A flavonoid glycoside and organic amine neuroagonist double salt compound, a preparation method therefor, and an application thereof, a pharmaceutical composition containing a therapeutically effective amount of the double salt compound ...  
WO/2022/083106A1
The present invention relates to the field of pharmaceutical chemicals, and relates to a method for preparing a glucosamine sulfate composite salt. The method comprises: adding N-acetylglucosamine and a solvent into a reaction vessel, th...  
WO/2022/084574A1
A method is presented for preparing samples for measuring a lignin content in a mass of pretreated lignocellulosic biomass particles. The pretreatment process comprises subjecting the lignocellulosic biomass particles to a hemihydrolysis...  
WO/2022/078612A1
The present invention relates to a method for releasing glycostructures from glycoproteins or enveloped viruses comprising glycostructures on their envelopes. Further, the invention relates to a method for isolating glycostructures from ...  
WO/2022/078487A1
The present disclosure provides a zolinose compound represented by formula (I), a preparation method therefor and a use thereof, wherein definitions of substituents are provided in the description. The zolinose compound has application p...  
WO/2022/075836A1
Provided are methods and systems for the production of alkyl polyglucoside. The methods and systems provide for improved purification that results in reduced produce degradation.  
WO/2022/072323A1
This specification relates to a process for preparing a purified human milk oligosaccharide ("HMO") from an HMO-containing solution (e.g., a fermentation broth) by a process comprising mixed bed ion exchange, and a product of such a proc...  
WO/2022/072333A1
This specification relates to a process for preparing a purified human milk oligosaccharide ("HMO") from an HMO-containing solution (e.g., a fermentation broth) by a process comprising anion ion exchange, cation ion exchange, and mixed b...  
WO/2022/067621A1
A sucralose purification method, sequentially comprising: putting sucralose in ultrapure water, heating for dissolving and then filtering, and extracting with an extraction solvent to remove non-polar impurities; evaporating an extracted...  

Matches 1 - 50 out of 3,612