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WO/2024/153021A1 |
Provided in the present invention are a paeoniflorin crystal form A, a preparation method therefor, and the use thereof. The crystal form A is represented by means of XRD, IR, DSC, TGA and the like. A powder diffraction pattern of the cr...
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WO/2024/153788A1 |
The present invention relates to processes for the purification of an oligosaccharide or oligosaccharide mixture from a solution, a product of such processes, and the use of a product of such processes.
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WO/2024/153787A1 |
The present invention relates to methods for the purification of a saccharide from a fermentation broth, a product of such processes, and the use of a product of such processes.
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WO/2024/153245A1 |
The present invention relates to the technical field of genetic engineering, and relates to two types of compounds for RNA capping and uses thereof. The compound has a structure as represented by formula (I), can be used as an initiating...
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WO/2024/153786A1 |
The present invention relates to methods for the purification of an oligosaccharide or oligosaccharide mixture from a fermentation broth, a product of such processes, and the use of a product of such processes.
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WO/2024/151257A1 |
Methods and systems for synthesizing an oligonucleotide in a reaction chamber comprising a solid support. A nucleotide monomer is selected for addition to an oligonucleotide. An inlet stream comprising the selected monomer is fed to the ...
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WO/2024/145726A1 |
The present invention comprises: first recovering trichloroethane and then recovering DMF, so as to remarkably reduce the impurity content of an obtained concentrated dry liquid, such that the yield and purity of an obtained sucralose-6-...
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WO/2024/146602A1 |
The present invention relates to a process of separating an acidic sophorolipid, or a lactonic sophorolipid, especially an acidic sophorolipid enriched with acetylated acidic sophorolipid from a lactonic/acidic sophorolipid-containing pr...
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WO/2024/138888A1 |
A process for synthesizing an emamectin benzoate intermediate 5-allyl formate-4"-methyleneaminoavermectin using an intermittent microchannel reactor. The reactor comprises two mixing modules and four reaction modules connected in series....
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WO/2024/144077A1 |
The present application relates to kestose in a crystalline form and a manufacturing method therefor.
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WO/2024/144004A1 |
The present application relates to: crystalline allulose exhibiting an X-ray powder diffraction (XRD) pattern in which peaks appear at 2θ diffraction angles of 18.8±0.5°, 15.2±0.5°, and 19.5±0.5° in an XRD analysis; a sweetener co...
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WO/2024/135721A1 |
The present invention addresses the problem of providing: a method for producing a production intermediate which is safe and advantageous for industrial production; a production intermediate thereof; and a method for producing a crosslin...
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WO/2024/133855A1 |
The present invention relates to methods for purifying and/or quantifying fucoidan from a sample, e.g. a sample of seawater. In particular, the invention provides a method for purifying fucoidan via an anion exchange chromatography colum...
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WO/2024/130904A1 |
A method for synthesizing a unique molecular identifier, the unique molecular identifier being a random oligonucleotide sequence. The method is completed by means of a nucleic acid synthesizer. During an activation coupling step of a sol...
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WO/2024/131789A1 |
The present application discloses injection-grade sucrose, a preparation method, and a use thereof. The bacterial endotoxin, sulfite, color value, conductivity, reducing sugar, and heavy metal of the injection-grade sucrose in the presen...
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WO/2024/124812A1 |
The present invention relates to a preparation method for a high-purity arabinose crystal. The preparation method comprises sequentially carrying out treatment processes including dissolution, blending, ion exchange, decolorization and f...
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WO/2024/125604A1 |
The present disclosure relates to diester derivatives of N4-hydroxycytidine (NHC), to pharmaceutical compositions thereof, and to the use and method of the diester derivatives of N4-hydroxycytidine to treat viral infections.
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WO/2024/125595A1 |
Provided are a gemcitabine anti-cancer derivative, the anti-cancer pharmaceutical use thereof, and a preparation method therefor. The compound has the potential to be developed into an anti-cancer drug activated by means of AKR1C3.
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WO/2024/125643A1 |
Provided is a method for preparing tumor-associated antigen DSGb5 glycolipid. Specifically, provided is an effective chemoenzymatic preparation method for preparing DSGb5 glycolipid antigen, of which the artificial preparation is complic...
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WO/2024/127026A1 |
The present invention relates to a membrane filtration-assisted process for the preparation of oligonucleotides by solution-phase synthesis. In particular, the present invention relates to a solution-phase process for preparing oligonucl...
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WO/2024/128835A1 |
The present invention relates to a novel compound derived from Loranthus tanakae and an anticancer use thereof. More specifically, the present invention provides: lotanoside B (indicated as rhamnetin -3-O-Rhamnoside-4'-O-(6"-O-cinnamoyl)...
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WO/2024/124314A1 |
The present invention relates to a sequential extraction process applied to citrus semi-solid waste with an emphasis on obtaining hesperidin, pectin, lignin and cellulose. The extraction process is applied in the reuse of industrial biom...
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WO/2024/121527A1 |
This invention relates to a novel process for the preparation of 5-fluoro-2'-deoxyuridine-5'-O-[1-naphthyl (benzoxy-L-alaninyl) ] phosphate (NUC-3373) and derivatives thereof. The NUC-3373 made according to this process is more stable th...
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WO/2024/121444A1 |
The present invention relates to a polyelectrolyte complex consisting of chitosan and phytic acid, the method for producing said polyelectrolyte complex using mechanochemical synthesis, and its use as an antimicrobial and antioxidant bio...
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WO/2024/119477A1 |
A preparation method for a psicose crystal, comprising the following steps: performing one-effect evaporation and concentration on a psicose solution to obtain a one-effect concentrated sugar solution; performing two-effect evaporation a...
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WO/2024/119464A1 |
A preparation method for sucralose, pertaining to the technical field of fine chemical engineering. The preparation method comprises the following steps: mixing sucrose, N,N-dimethylformamide, trichloroethane, and thionyl chloride, and c...
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WO/2024/119657A1 |
The present invention relates to supported zinc trifluoroacetate, a preparation method and the use. Zinc trifluoroacetate supported by styrene-divinylbenzene resin microspheres is used as the supported zinc trifluoroacetate. The preparat...
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WO/2024/114485A1 |
The present invention relates to a fluorescence turn-on nucleoside, a preparation method therefor and a use thereof. The structural formula of the fluorescence turn-on nucleoside is as shown in formula (1). The preparation method can obt...
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WO/2024/112800A1 |
The present disclosure provides methods for deprotecting and purifying an oligomeric compound. The method provides for deprotection of a protecting group, which may be a trityl protecting group, and removal of a byproduct by diafiltratio...
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WO/2024/112637A1 |
Described herein are novel methods of preparing sphingosines and glycosylated sphingosines. A method of preparing a glycosylated sphingosine as described herein includes an efficient, four-step route for synthesizing lactosylsphingosine ...
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WO/2024/112877A1 |
Methods are disclosed for making a targeting ligand-conjugated nucleotide phosphoramidite known as adem-A-GalNAc phosphoramidite, which can be used in the synthesis of oligonucleotides such as therapeutic oligonucleotides.
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WO/2024/112865A1 |
Methods are disclosed for making a 4'-phosphate analog phosphoramidite known as MeMOP, which can be used in the synthesis of oligonucleotides such as therapeutic oligonucleotides.
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WO/2024/105051A1 |
The present invention relates to a method for preparing an at least partially acetal-protected sugar involving the step of reacting a sugar or a sugar derivative selected from the group consisting of an aldopentose, an aldohexose, an ald...
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WO/2024/098964A1 |
Provided in the present invention are a vinylphosphonic acid-modified mRNA cap analogue, and a preparation method therefor and the use thereof. The vinylphosphonic acid-modified mRNA cap analogue of the present invention has a more stabl...
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WO/2024/099487A1 |
The invention relates to oligosaccharides composed of alternating glucose and N- acetylglucosamine units with a double bond in position 4 of the terminal non-reducing saccharide (glucose) and with the primary hydroxyl group in position 1...
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WO/2024/102605A1 |
The present disclosure relates generally to improved methods of preparing glycoconjugates. The methods comprise using a reducing mixture containing acetoxyborohydrides prepared in-situ for conjugating a saccharide to a carrier protein.
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WO/2024/094607A1 |
The present invention generally relates to the field of isotope labeled and non-labeled gentamicin congeners and synthetic methods for the preparation of such congeners. In particular, the present invention relates to isotope labeled gen...
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WO/2024/092506A1 |
A sample processing module (100), comprising a first lifting/lowering plate (120), a fixing plate (140), a hollow threaded tube (160) and a first driving member (180). The first lifting/lowering plate (120) is coupled to the first drivin...
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WO/2024/087720A1 |
Provided in the present invention are a compound for a TLR8 inhibitor, and a preparation method therefor and the use thereof, which relate to the technical field of small molecule pharmaceutical compounds. The compound of the present inv...
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WO/2024/089953A1 |
The present invention provides a method for producing oligonucleotide by a solid-phase synthesis technique, wherein said method for producing oligonucleotide comprises a step for reacting, in the presence of a thiol, an acid with an olig...
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WO/2024/083491A1 |
The invention relates to an oligosaccharide of formula I derived from rare sugars, wherein R, X and n have the meanings defined in the specification. The invention also relates to its process to obtain it and to its use as a prebiotic an...
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WO/2024/082175A1 |
The present invention provides a preparation method for a sucralose refined product, and relates to the technical field of fine chemical engineering. In the present invention, by means of subjecting a sucralose crude product to ethyl ace...
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WO/2024/082158A1 |
Provided in the present invention is a method for preparing a sucralose crude product by using a sucralose-6-acetate crystallization mother liquor. In the present invention, by using an alkali metal hydroxide for alkaline hydrolysis, suc...
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WO/2024/083746A1 |
The invention pertains to methods for the synthesis of oligonucleotides using pseudo solid-phase protecting groups, wherein said method comprises at least one aqueous extraction carried out in the presence of one or more amide solvents S...
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WO/2024/082156A1 |
The present invention provides a method for preparing a sucralose crude product by using an alcohol-water alkaline hydrolysis system, and relates to the technical field of fine chemical engineering. In the present invention, an aqueous s...
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WO/2024/082154A1 |
The present invention provides a method for preparing a sucralose crude product by using an alcohol-water alkaline hydrolysis system, and relates to the technical field of fine chemical engineering. In the present invention, an aqueous s...
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WO/2024/082157A1 |
The present invention relates to the technical field of fine chemical engineering, and provides a method for preparing a crude sucralose by using an alcohol-water alkaline hydrolysis system. According to the present invention, a sucralos...
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WO/2024/086623A1 |
A method of separating and recovering a first carbohydrate from a feed solution comprising two or more carbohydrates and salts using a chromatography separation system which comprises one or more strong acid cation exchange resin, and re...
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WO/2024/082177A1 |
The present invention provides a method for preparing a sucralose crude product by using an alcohol-water alkaline hydrolysis system, and relates to the technical field of fine chemical engineering. In the present invention, an aqueous s...
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WO/2024/077410A1 |
The present application relates to the technical field of metal ion chemistry, and provides a method for reducing an azide methoxy group, a sequencing method, and a kit. The method for reducing an azide methoxy group provided by the pres...
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