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Matches 351 - 400 out of 864

Document Document Title
JP4773336B2
The present invention provides methods for preparing LPS antagonist lipodisaccharide B1287 and stereoisomers thereof, which compounds are useful as in the prophylactic and affirmative treatment of endotoxemia including sepsis, septicemia...  
JP4726477B2  
JP4725976B2
The present invention is directed to a one-step process for the preparation of fructopyranose sulfamate derivatives of the general formula (I) wherein X, R1, R3, R4, R5 and R6 are as described in the specification.  
JPWO2009102022A1
本発明は、β−O−ピラノシドを選択的に、 かも簡便に製造するためのβ−O−グリコ ル化剤として有用な3,6−O−架橋反転 ラノース化合物を提供することを課題...  
JP2011516478T
In the medical treatment and prevention of the fall of microorganism infection and an immunity system, the disease from which the cell serves as an obligate anaerobiosis, and a cell-growth disease including cancer, the present invention ...  
JP2011516478A
The present invention provides novel immunotherapeutic compositions and methods useful for treating or preventing microbial infections, weakened immune systems, diseases in which cells have become obligately anerobic and cellular prolife...  
JP2011037885A
To provide methods for preparing LPS (linear programming system) antagonist lipodisaccharide B1287 and stereoisomers thereof.The invention provides methods for preparing LPS antagonist lipodisaccharide B1287 useful in the prophylactic an...  
JP4610197B2  
JP2010285446A
To provide processes for producing alkylamino glucosaminide phosphate compounds and disaccharide compounds functioning as immunoeffectors or adjuvants intended for vaccines and the like comprising various novel intermediates and intermed...  
JP4599295B2  
JP4577478B2  
JP2003012683A5  
JP2010189410A
To provide a new aminobenzophenone derivative which has excellent physicochemical properties, especially has improved bioavailability, and is pharmacologically active.The new aminobenzophenone derivative is represented by general formula...  
JP2010528048A
A method for preparing isofagomine, its derivatives, intermediates and salts thereof using novel processes to make isofagomine from D-(-)-arabinose and L-(-)-xylose.  
JP4504018B2
A compound of the formula : wherein R 1 is -H, -SPh, -Ph, -allyl or -benzyl; R 2 is -H, -Et, -allyl, -Me or -benzyl; R 3 is -H, -Et, -Me, -allyl or -benzyl; and R 4 and R 5 are both -OH or R 4 and R 5 together form a ring and are -OCH(Ph...  
JPWO2008111526A1
The manufacturing process of the glycoside which uses the manufacturing method in which an oxazoline derivative is simpler than unprotected sugar, and its output is provided. The sugar oxazoline derivative is compounded at one step of pr...  
JPWO2008096880A1
本発明は、未だ確立されていない効率的な糖 脂質合成法を開発することを課題とする。本 発明により、糖脂質を生成するための方法が 提供される。この方法は、以下:(a)...  
JP2010070541A
To provide a TG synthesis inhibitor effective for prevention or amelioration of hyperlipidemia and obesity.The TG synthesis inhibitor comprises as an effective ingredient thereof ellagitannin, having a partial structure represented by fo...  
JP2010070462A
To provide an industrially more advantageous method for producing 2,2'-anhydroarabinosylthymine which is a suitable intermediate for producing a nucleic acid derivative such as L-thymidine.A 2,2'-anhydro-5,6-dihydrouridine-5-alkoxymethyl...  
JP2010065038A
To provide conjugates of fatty alcohols and pharmaceutical agents useful in treating cancer, viral deseases, psychiatric disorders.Compositions (1) are expressed by chemical formula (1). In the formula, R is an 8-26C fat group of a fatty...  
JP4435305B2  
JP2010501598A
The invention provides compounds of formula (I) for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds. The invention also provides methods...  
JP4393863B2  
JP4347488B2
A process for the addition of an azide function to an organic compound in which process a mixture is prepared by adding an epoxide-derivative of the organic compound and an alkali metal azide salt to a solvent is described. The mixture i...  
JPWO2009102022A
The present invention makes it a subject to provide a useful as beta*O * glycosylation agent for manufacturing beta*O * pyranoside alternatively and simple 3, and 6*O* bridge construction reversal pyranose compound. A 3 of the present in...  
JP4294317B2
A chemically amplified photoresist composition comprising, (a) a compound which cures upon the action of an acid or a compound whose solubility is increased upon the action of an acid; and (b) as photosensitive acid donor, at least one c...  
JP2009515899A
The present invention is based, in part, on our discovery that certain types of therapeutic agents can be used in combination to treat a variety of neuropsychiatric and related disorders, including addiction (e.g., to a substance or to a...  
JP4251410B2
Anticonvulsant derivatives useful in treating psoriasis are disclosed. 00000  
JP2008545650A
[化 1] The present invention relates to the production method of a スルホニル imine derivative [especially, thing of the thing] of formula (XII) and the スルファミド derivative [, especially formula (I)]. This method under ex...  
JP4182218B2
A novel glucose derivative inducing apoptosis. The glucose derivative is represented by the following general formula (I) wherein X, Y and Z are the same or different and each is hydrogen, halogenoalkyl, hydroxy, or alkoxy, provided that...  
JP2002201372A5  
JP4162491B2
The present invention provides stable compounds prepared from boronic acid and lyophilized compounds thereof of formula (1) in which Z 1 and Z 2 are moieties derived from sugar. The invention also provides methods for preparing such comp...  
JPWO2008111526A
A manufacturing process of a glycoside which uses a manufacturing method in which an oxazoline derivative is simpler than unprotected sugar, and its output is provided. The sugar oxazoline derivative is compounded at one step of processe...  
JP4153057B2
Trehalose is oxidized to give oxidized trehalose which then is hydrolyzed to produce D-glucuronolactone which is thereafter recovered to realize high-yield and low-cost production of D-glucuronolactone.  
JPWO2008096880A
The present invention makes it a subject to develop the efficient glycolipid synthesis method which is not yet established. The method for generating a glycolipid is provided by the present invention. This method makes the sugar and lipi...  
JP2008531604A
The invention comprises compounds for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions containing the compounds or prodrugs of the compounds. The invention also comprises animal models and m...  
JP4097294B2
The present invention describes a method for treating neuropathic pain comprising administering to a mammal afflicted with such condition a therapeutically effective amount for treating such condition of a compound of formula (I), wherei...  
JP2007530700A
Compounds and methods useful in the control, treatment, and prevention of fungal activity, of the following formula: where R1-3 are independently H, alkyl, methyl, acyl, halogen, phenyl, R4 is H, alkyl, methyl, acyl, alkoxy, halogen, phe...  
JP3992510B2  
JP2007527520A
Methods are disclosed for providing a library of composite or novel composition samples on a support. The method involves depositing one or more components as concentration gradients on the surface of the support. The concentration gradi...  
JP2007230930A
To provide a glycosyl donor compound enabling stereoselective 1,2-cis glycosylation reaction. The compound is expressed by formula (1) (X1 and X2 are each independently hydrogen atom or hydroxyl-protecting group; Y is a 7-20C aralkyl gro...  
JP2007197362A
To obtain a sialic acid derivative as a saccharide donor, which forms a glycosyl bond having a high yield and high α selectivity in a glycosylation reaction of a saccharide receptor using a sialic acid as a saccharide donor. The sialic ...  
JP3942414B2
To provide a new efficient synthesis method for industrially producing an L-type nucleic acid derivative as a medicine. A method by which the L-type nucleic acid derivative can industrially be produced from L-arabinose, one of few indust...  
JP2002537326A5  
JP2002536328A5  
JP2004505004A5  
JP2006232861A
To provide a novel efficient synthetic method for industrially producing an L-nucleic acid derivative as a medicine.Provided is the method industrially producing the L-nucleic acid derivative in a short process by using L-arabinose which...  
JP2006519860A
The present invention is directed to a one-step process for the preparation of fructopyranose sulfamate derivatives of the general formula (I) wherein X, R1, R3, R4, R5 and R6 are as described in the specification.  
JP2006518759A
It is taught here that enkephalin peptides which are glycosylated with a disaccharide will be transported across the blood brain barrier and deliver analgesic effects superior to morphine when introduced into the bloodstream. Glycosylate...  
JP2006518394A
The present invention provides methods for preparing LPS antagonist lipodisaccharide B1287 and stereoisomers thereof, which compounds are useful as in the prophylactic and affirmative treatment of endotoxemia including sepsis, septicemia...  

Matches 351 - 400 out of 864