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WO/1998/052906A1 |
The compounds of formula (I) in which: A represents C�6?-C�10? aryl or an optionally aromatic three- to ten-membered heterocycle; X represents halogen, cyano, C�1?-C�7? alkyl, trifluoromethyl, C�2?-C�7? alkoxy or trifluoromet...
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WO/1998/050337A1 |
The invention relates to 2-(3-alkenyl-benzoyl)-cyclohexane-1,3-diones of formula (I), wherein the variables can have the following meanings: R?1�, R?2� = hydrogen, nitro, halogen, cyano, rhodano, alkyl, halogen alkane, alkoxyalkyl, a...
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WO/1998/049152A1 |
Compounds of formula (I), wherein R?l� is an aromatic or a heteroaromatic ring; R?2� and R?3� are H, C�1?-C�8?alkyl, aryl, arylC�1?-C�8?alkyl, or heteroaryl; R?4� is an aromatic or a heteroaromatic ring or an amine; W, X,...
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WO/1998/047843A1 |
Preparation of 2,5-dichlorophenol by selectively oxidizing 1,4-dichlorobenzene using a peroxo-, hydroperoxo-, superoxo- or alkylperoxo-metal species in the presence of formic or an alkanoic acid.
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WO/1998/046547A1 |
A process is disclosed for preparing 2-aryl-substituted indenes by reacting an indene with an arene compound substituted with an halogen atom, preferably a iodine atom, or with an organosulphonate group, said reaction being carried out i...
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WO/1998/046557A1 |
The invention relates to aromatic amines which are produced by catalytically hydrogenating corresponding aromatic nitrocompounds in a gaseous phase. Hydrogenation is carried out in the presence of catalysts which contain palladium, vanad...
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WO/1998/042653A1 |
A process for producing carboxylic acid esters by reacting an aldehyde with an alcohol in a liquid phase in the presence of molecular oxygen and a catalyst composed of at least palladium and X (which is bismuth and/or lead) supported by ...
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WO/1998/042654A1 |
A process for separately isolating 3-nitro-o-toluic acid and 5-nitro-o-toluic acid from a mixture of both, which comprises adding an aromatic organic base such as aniline or pyridine to the mixture to form the corresponding salts, throwi...
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WO/1998/042328A1 |
The present invention relates, $i(inter alia), to compounds that bind tubulin and exhibit anti-mitotic properties and to methods of using such compounds to inhibit abnormal cell mitosis and, in particular, to inhibit tumor cell growth. I...
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WO/1998/041518A1 |
The invention concerns a method for preparing a compound of formula (I) in which R�1? to R�5?, n and Ar are as defined in claim 1, comprising thermal cyclization of a compound of formula (IV).
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WO/1998/040337A1 |
An adamantane derivative having a functional group such as nitro, amino, hydroxyl, carboxyl, hydroxymethyl or isocyanato is oxidized with oxygen in the presence of an imide compound of general formula (2) (such as N-hydroxyphthalimide) o...
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WO/1998/040338A1 |
There is disclosed a process for the preparation of a compound of general formula (I), wherein Y and Z each independently represent a fluorine atom or a hydroxy group, and a, b, c and d independently represent 0, 1, 2 or 3 provided that ...
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WO/1998/040347A1 |
A process for the purification of a compound of general formula (I), wherein R1 is hydrogen or C�1?-C�6? alkyl, C�2?-C�6? alkenyl or C�2?-C�6? alkynyl, any of which may optionally be substittuted with one or more substituents...
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WO/1998/040339A1 |
The invention concerns a method for the acylation or sulphonation of an aromatic compound. More particularly, the invention concerns a method for the acylation or sulphonation of an activated or deactivated aromatic compound and is usefu...
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WO/1998/039323A1 |
Methoxy and ethoxy substituted 3-aroyl-2-arylbenzo[$i(b)]thiophenes and benzo[$i(b)]thiophene analogues are described for use in inhibiting tubulin polymerization. The compounds' use for treating tumor cells is also described. Additional...
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WO/1998/039287A1 |
The present invention relates to benzanthrones and benzanthrone derivatives having antiviral properties and to antiviral compositions that include at least one benzanthrone or benzanthrone derivative having antiviral properties. Benzanth...
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WO/1998/039281A1 |
New 2-aryl-3-hydroxy-$g(D)?2�-cyclopentene-1-one derivatives of formula (I) are disclosed, in which A, B, D?1�, D?2�, G, W, X, Y et Z have the meanings given in the description, as well as processes for preparing the same and their...
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WO/1998/035932A1 |
A process for producing 3-nitro-o-toluic acid which comprises oxidizing 3-nitro-o-xylene with oxygen or an oxygenic gas in a solvent based on a lower aliphatic carboxylic acid in the presence of a heavy metal catalyst and a reaction acce...
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WO/1998/034898A1 |
The invention relates to phenoxyacetic acid derivatives of formula (I), wherein R�1?, R�2?, Xn and A are as defined in the description, A represents a halogen atom, hydroxy, OR�3?, S(O)�k?R�3?, or a group of formula (A-1) or (A...
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WO/1998/032532A1 |
A catalyst for halogen-fluorine exchange reactions of aromatic compounds essentially consists of a mixture of one or more compounds (a) and at least one compound (b), (c) and/or (d). (a) is an amidophosphonium salt of formula (I), in whi...
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WO/1998/030329A1 |
At least one functional group selected between nitro and carboxyl groups can be introduced into a substrate by bringing the substrate into contact with at least one reactant selected from among (i) nitrogen oxides and (ii) carbon monoxid...
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WO/1998/024740A1 |
A method of fluorinating an aromatic compound substituted by a moiety comprising a carbonyl group comprises contacting the compound with fluorine. A selective method of fluorinating in the 2-position an aromatic compound substituted at i...
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WO/1998/024753A1 |
Optically active 1-(substituted phenyl)-2-nitro alcohol derivatives represented by general formula (1) and a process for preparing the same, and 1-(substituted phenyl)-2-amino alcohol derivatives represented by general formula (2) and a ...
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WO/1998/022496A2 |
The invention provides amino acid derivatives of formula (I) wherein E represents CHO or B(OH)�2?; R?1� represents lower alkyl (optionally substituted by halo, cyano, lower alkylthio, aryl-lower alkylthio, aryl or heteroaryl), lower ...
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WO/1998/022438A1 |
The invention relates to novel cyclic imines of formula (I) wherein Ar?1�, Ar?2� mean in each case substituted phenyl and n is 1,2 or 3; several methods for the production and the use thereof as pesticides.
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WO/1998/021175A1 |
A method is disclosed for the preparation of optically pure isomes of formeterol, especially the ($i(R,R))- and ($i(S,S))-isomer, by the reaction of an optically pure 4-benzyloxy-3-formamidostyrene oxide with an optically pure 4-methoxy-...
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WO/1998/019988A1 |
Briefly, in one aspect, the present invention provides compositions of open-chain, $g(a)-branched fluoroalkylcarbonyl fluorides, and derivatives thereof.
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WO/1998/020344A1 |
The invention includes compositions comprising, and methods of using, 1,2-indanedione derivatives for detecting an amine compound suc has an amino acid. Methods of detecting and recording the pattern of a fingerprint on a surface are als...
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WO/1998/019978A1 |
A process for the nitration of an aromatic or heteroaromatic compound with a nitrating agent comprising nitric acid or a mixture of nitric and sulphuric acids, characterised in that nitration is performed in a solvent comprising at least...
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WO/1998/016222A1 |
The present invention relates to novel itermediates of formula (1) wherein the wavy bond ($m(k) $m(k)) represents the racemate, the (R)-enantiomer or the (S)-enantiomer; and R is hydrogen, a carboxyl-protecting group or a cation of an ad...
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WO/1998/016486A1 |
A process for the preparation of a substituted aromatic compound in which a chloroaromatic compound and an alkyl-, alkenyl- or aryl-boronic acid, ester or anhydride are coupled in the presence of palladium and a lipophilic aliphatic phos...
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WO/1998/013341A1 |
The invention relates to hydroxybenzophenone derivatives of formula (I), wherein R?1�, R?2�, R?3�, R?4�, R?5�, R?6�, R?7� and R?8� are as defined in the description, and to their use as herbicides.
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WO/1998/011046A2 |
This invention relates to processes for the preparation of aryl-$g(b)-diketones and aryl-pyrimidine ketones. In addition, this invention relates to the preparation of aryl-$g(b)-triketones and dimethyl aminomethylene $g(b)-diketones, whi...
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WO/1998/007809A2 |
The present invention relates to hard surface cleaning compositions which comprise $g(b)-ketoester pro-fragrance compounds which provide cleaned hard surfaces with an enhance fragrance or odor benefit. The pro-fragrances once delivered c...
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WO/1998/007810A2 |
The present invention relates to a fragrance delivery system for use in hand-wash laundry detergent compositions which provides a long lasting 'freshness' or 'clean' scent to fabric. The compositions described herein deliver highly fabri...
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WO/1998/007407A1 |
The present invention relates to personal care and personal hygiene articles containing a fragrance delivery system which comprises one or more pro-accords, preferably $g(b)-ketoester pro-accords, which are capable of releasing mixtures ...
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WO/1998/007814A2 |
The present invention relates to a fragrance delivery system for use in liquid laundry detergent compositions which provides a long lasting 'freshness' or 'clean' scent to fabric. The compositions described herein deliver highly fabric s...
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WO/1998/007811A2 |
The present invention relates to a fragrance delivery system for use in laundry detergent compositions which provides a long lasting 'freshness' or 'clean' scent to fabric. The compositions described herein deliver highly fabric substant...
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WO/1998/007717A1 |
A novel process for preparing zaltoprofen[2-(10,11-dihydro-10-oxodibenzo[b,f]thiepin-2-yl)
propionic acid], which, as compared with the conventional processes, has better practicality from an overall viewpoint including availability and ...
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WO/1998/007405A1 |
The present invention relates to a fragrance delivery system which comprises one or more pro-accords, preferably $g(b)-ketoester pro-accords, which are capable of releasing mixtures of fragrance raw materials. The pro-accords which compr...
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WO/1998/007455A1 |
The present invention relates to a fragrance delivery system which comprises one or more $g(b)-ketoester pro-fragrances or pro-accords, said fragrance delivery system useful in a stable, preferably clear, aqueous odor-absorbing compositi...
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WO/1998/007812A2 |
The present invention relates to Automatic Dishwasher Detergent (ADD) compositions having a fragrance delivery system which comprises $g(b)-ketoester pro-fragrances which are capable of releasing fragrance raw materials which provide an ...
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WO/1998/007683A1 |
The present invention relates to methods for preparing $g(b)-ketoesters which include the steps of reacting phosgene or a phosgene equivalent with an alcohol to form a chloroformate and reacting the chloroformate with a ketone in the pre...
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WO/1998/007813A2 |
The present invention relates to a fragrance delivery system for use in laundry detergent compositions which provides a long lasting 'freshness' or 'clean' scent to fabric. The compositions described herein deliver highly fabric substant...
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WO/1998/006692A1 |
Cyano and carboxy derivatives of substituted styrenes of formula (I), in which Y is -COZ, -C$m(Z)N, or lower alkyl of 1 to 5 carbon atoms; Z is -OH, -NR?6�R?6�, -R?7�, or -OR?7�; X, R?1�, R?2�, R?3�, R?4�, R?5�, R?6�,...
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WO/1998/005610A2 |
A process is disclosed for preparing fluorine-containing compounds by reacting a compound which contains a halogen that can be replaced by fluorine with a fluoride or a mixture of fluorides of general formula (I): MeF, in the presence of...
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WO1998004508A1 |
Selective IgE production inhibitors which contain substances inhibiting the production of IgE in the process of the differentiation of matured B cells into antibody-producing cells and the production of the antibody thereby while not or ...
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WO/1998/003458A1 |
The present invention provides illudin analogs of general formula (I) where R�1? is (CH�2?)�n?-X-Y or H; n is 0 to 4; X is O or S or N or absent; and Y is an optionally substituted (C�1?-C�8?)alkyl, (C�6?-C�10?)aryl, (C�6...
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WO/1998/003452A1 |
'Three-dimensional' polymers of very small size can be used in the context of synthesis. These polymers provide simple isolation routes by avoiding the need for workup following the reactions, pre-workup characterization, high yield, hig...
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WO/1998/002408A1 |
The invention concerns a method of nitrosation of a phenolic compound substituted by an electro-attracting group.The invention also concerns a method of nitration of a phenoic compound substituted by an electro-attracting group. The nitr...
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