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WO/2015/089639A1 |
The present application is directed to excimer forming compounds of Formula I: W-V-[Y]n wherein W is an excimer forming fluorophore, V is a linker moiety, Y is a metal ion coordinating moiety and n is 1, 2 or 3. In particular, the applic...
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WO/2015/086659A1 |
A lithographic printing plate precursor is disclosed including i) a support having a hydrophilic surface or which is provided with a hydrophilic layer, and (ii) a coating including a photopolymerisable layer, characterised in that the ph...
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WO/2015/083740A1 |
Provided are: a compound that uniformly stabilizes a composition containing a fluid organic substance, or thickens or gels the fluid organic substance to a desired viscosity; a thickener/stabilizer containing the compound; a thickened/st...
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WO/2015/082938A1 |
The present invention relates to a compound of formula I, or a pharmaceutically acceptable salt thereof : (I) wherein: n is 0 or 1; R1 is selected from H, alkyl and aralkyl, wherein said alkyl and aralkyl groups may be optionally substit...
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WO/2015/076296A1 |
The present invention relates to: a bromine-containing N-phenyldi(meth)acrylimide derivative represented by general formula (1) (wherein R1, R2, m and k are as described in the description and claims), which is useful as a reactive flame...
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WO/2015/073648A1 |
Amines and amine derivatives that improve the buffering range, and / or reduce the chelation and other negative interactions of the buffer and the system to be buffered. The reaction of amines or polyamines with various molecules to form...
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WO/2015/073524A1 |
The present invention provides a method of treating or prevent a disease or disorder selected from the group consisting of Alzheimer's Disease, cerebral amyloid angiopathy, and Parkinson's Disease in a mammal in need thereof. In certain ...
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WO/2015/070995A1 |
The present invention relates to a process for the preparation of optically pure ( R) -1-aminoindan by a diastereomeric resolution of 1-aminoindan using N-acetyl-L-glutamic acid as a resolving agent. In another aspect, the invention rela...
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WO/2015/068770A1 |
A method for producing carboxylic acid amide that obtains carboxylic acid amide by dehydrocondensation of carboxylic acid and amine, wherein arylboronic acid having an electron-attracting group at the meta position and/or para position i...
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WO/2015/069810A1 |
The present disclosure provides novel methods for treating cardiac remodeling and heart conditions using specific compounds, as well as compositions, and pharmaceutical formulations. In some embodiments, the compounds may inhibit acetyla...
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WO/2015/063020A1 |
The present invention relates to a process for the preparation of aqueous solutions of [1-13C]-hyperpolarized carboxylate containing molecules of diagnostic interest that comprises parahydrogenating with molecular parahydrogen unsaturate...
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WO/2015/064678A1 |
Provided is a method for producing an aqueous solution having a pH within the range of 8.4 to 9.5, and containing a N-C8-22 acyl acidic amino acid and/or a salt thereof. The method contains: a first step in which an acidic amino acid and...
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WO/2015/063086A1 |
The present invention relates to novel benzocyclobutane(thio) carboxamides, to processes for preparing these compounds, to compositions comprising these compounds, and to the use thereof as biologically active compounds, especially for c...
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WO/2015/060402A1 |
Provided are a novel production method for trifluoromethanesulfonanilides, which are useful as herbicides, etc., and intermediates therefor. Specifically provided are: an industrially-useful production method for producing a trifluorom...
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WO/2015/060657A1 |
The present invention relates to a method for preparing an intermediate of iopromide, and more particularly, to a method for preparing an intermediate of iopromide, in which 5-methoxyacetylamino-2,4,6-triiodoisophthalic acid dichloride i...
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WO/2015/055844A1 |
The invention relates to an hydrolysis vessel (200) used during amidification step of acetone cyanohydrin (ACH), in the industrial process for production of a methyl methacrylate (MMA) or methacrylic acid (MAA). The hydrolysis vessel (20...
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WO/2015/056782A1 |
The purpose of the present invention is to provide a novel compound having ACC2-inhibiting activity and to provide a pharmaceutical composition comprising said compound. A compound indicated by formula (in the formula, R1 indicates a sub...
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WO/2015/055806A1 |
The present invention provides a system for evaporating a radioactive fluid, a method for the synthesis of a radiolabelled compound including this system, and a cassette for the synthesis of a radiolabelled compound comprising this syste...
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WO/2015/054476A1 |
Methods of halogenating a carbon containing compound having an sp3 C-H bond are provided. Methods of fluorinating a carbon containing compound comprising halogenation with Cl or Br followed by nucleophilic substitution with F are provide...
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WO/2015/049294A1 |
This disclosure relates to flavour modification and to compounds of formula (I) wherein R1 is selected from C2-C20 alkyl, and C6-C25 alkenyl, and a) R2 and R3 together are -C(O)CH2CH2-; or b) R3 is hydrogen and R2 is -CH2CH2C(O)NHCH2CH3 ...
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WO/2015/048990A1 |
This disclosure relates to flavour modification and to compounds of formula (I) wherein R1 is selected from C6-C20 alkyl, and C9-C25 alkenyl, R5 is C1-C3 alkyl, and a) n is 1; and i) R3 and R4 are hydrogen and R2 is the residue of a prot...
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WO/2015/049275A1 |
A stock solution comprising a compound of formula (I) wherein R1 together with the carbonyl group to which it is attached is a residue of a carboxylic acid, and NR2R3, in which R3 is H or together with R2 and the N-atom to which they are...
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WO/2015/050534A1 |
This disclosure relates to flavour modification and to compounds of formula (I) wherein R1 is selected from C6-C20 alkyl, and C9-C25 alkenyl, and i) R3 and R4 are hydrogen and R2 the residue of a proteinogenic amino acid; ii) R2 and R3 a...
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WO/2015/050536A1 |
A compound according to the formula (I) or edible salts thereof, [Formula should be inserted here] Wherein R together with the carbonyl group to which it is attached is a residue of a carboxylic acid. Said compounds may be used in edible...
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WO/2015/050535A1 |
This disclosure relates to flavour modification and to compounds of formula (I) wherein R1 is selected from C2-C20 alkyl, and C6-C25 alkenyl, and a) R2 and R3 together are -C(0)CH2CH2-; or b) R3 is hydrogen and R2 is -CH2CH2C(0)NHCH2CH3,...
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WO/2015/043522A1 |
The present invention relates to trifluoromethyl-containing amide alkaloid, a manufacturing method thereof, pharmaceutical combinations containing same, and pharmaceutical use thereof. The trifluoromethyl-containing amide alkaloid of the...
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WO/2015/048553A1 |
The invention provides compositions and methods for wound healing and scar reduction. The compositions and methods of the invention Include at least one EP4 agonist set forth herein. Wounds and or scars that can be treated by the composi...
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WO/2015/046317A1 |
The purpose of the present invention is to provide novel acethylene amide derivatives, i.e., a compound having an antagonistic activity on all of PPARα, PPARβ/δ and PPARγ, a compound having an antagonistic activity on at least one su...
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WO/2015/039172A1 |
The present invention relates to novel compounds and their use in the prophylactic and/or therapeutic treatment of hypertension and/or fibrosis.
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WO/2015/042561A1 |
The invention provides a thermoplastic polymer composition comprising a polyolefin polymer and a nucleating agent. The nucleating agent comprises a compound conforming to the structure of Formula (I). The invention also provides a series...
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WO/2015/042563A1 |
The invention provides a compound conforming to the structure of Formula (CX). The invention also provides a thermoplastic polymer composition comprising a polyolefin polymer and a compound conforming to the structure of Formula (CX) as ...
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WO/2015/040141A1 |
Compounds of the formula (I), in which the substituents are as defined in claim 1, are suitable for use as nematicides.
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WO/2015/039173A1 |
The present invention relates to a novel terphenyl compound and its use in the prophylactic and/or therapeutic treatment of hypertension and/or fibrosis.
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WO/2015/042569A1 |
A polyethylene article comprises crystalline polyethylene in an orthorhombic unit cell. The b-axes of the crystalline polyethylene are substantially aligned with the machine direction of the article. In particular, the Herman's index of ...
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WO/2015/042565A1 |
The invention provides a compound conforming to the structure of Formula (CXX). The invention also provides a thermoplastic polymer composition comprising a polyolefin polymer and a compound conforming to the structure of Formula (CXX) a...
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WO/2015/042562A1 |
The invention provides a compound conforming to the structure of Formula (C). The invention also provides a thermoplastic polymer composition comprising a polyolefin polymer and a compound conforming to the structure of Formula (C) as a ...
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WO/2015/037460A1 |
Optically active 3-(biphenyl-4-yl)-2-[(t-butoxycarbonyl)amino]propan-1-ol can be produced through: a step of reacting an optically active biphenylalanine compound represented by formula [I] with a reducing agent to produce an optically a...
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WO/2015/037892A1 |
The present invention relates to: a novel bis-amide derivative compound or a pharmaceutically acceptable salt thereof; a preparation method therefor; and a pharmaceutical composition for preventing or treating diseases caused by hepatiti...
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WO/2015/035833A1 |
Disclosed is a compound of general formula (I) with a function of pseudoceramide, and usage thereof in preparing personal care products for skin, hair and the like and topical pharmaceuticals, wherein R1, R2, R3, m and n are defined in t...
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WO/2015/032069A1 |
Provided is a photo-initiator of formula (I), wherein PI is a photo-initiator group containing an aromatic ring capable of initiating a free-radical polymerization reaction when being exposed to actinic radiation, and is connected to Y t...
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WO/2015/033781A1 |
A method for producing a dipeptide that has a protected N-terminal and is represented by formula (1) or a salt of the dipeptide, said method comprising condensing an α-monosubstituted amino acid that has a protected N-terminal and is re...
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WO/2015/034820A1 |
Disclosed are compounds of Formula (I): (I). Also disclosed are methods of using such compounds as immunomodulators, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowin...
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WO/2015/027773A1 |
The present invention relates to an application of dimethylaminopyridine (DMAP) hydrochloride serving as recyclable catalyst in an acylation reaction (as represented by equation I). The application comprises: dissolving DMAP into a nonpo...
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WO/2015/026538A1 |
N-Acyl amino acid salt compositions and an improved process for making them from fatty alkyl esters are disclosed. The process comprises reacting a fatty alkyl ester with an amino acid salt in the presence of an alkoxide catalyst at a pr...
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WO/2015/024385A1 |
The invention provides a preparation method of N-acyl acidic amino acid or a salt thereof, comprising subjecting a fatty acyl chloride and an amino acid to an amidation reaction under an alkaline condition. The preparation method is char...
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WO/2015/025326A1 |
The present invention provides 3-(4-ethynylphenyl) pyridopyrimidinone compounds of formula A as potential anticancer agents. 3-(4-ethynylphenyl) pyridopyrimidinone compounds have shown promising anticancer activity in various cell lines ...
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WO/2015/024991A1 |
The invention relates to a novel synthesis route towards R- biphenylalaninol and to the intermediates applied in this synthesis route. The process according to the invention and the intermediate compounds are useful in the synthesis of p...
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WO/2015/021535A1 |
The disclosure provides methods and uses for alleviating and/or treating pain including pain disorders using melatonin ligands of Formula I: or pharmaceutically acceptable salts thereof wherein: n is 1 or 2; m is 0, 1 or 2; p is 0, 1, 2,...
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WO/2015/019928A1 |
The present invention relates to a novel synthesis method that is capable of producing an optically active binaphthyldiamine derivative, under conditions whereby the binaphthyldiamine derivative can be produced more safely and efficientl...
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WO/2015/014900A1 |
The present invention refers to compounds of formula (I): as well as to a method for their preparation, pharmaceutical compositions comprising the same, and use thereof for the treatment and/or prevention of conditions associated with th...
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