| Document |
Document Title |
|
WO/2003/072063A2 |
Compounds useful as antiproliferative agents, including, for example, anticancer agents, are provided according to formula (I): wherein:Ar, X, X1, g, R and R3 are as defined herein.
|
|
WO/2003/070690A2 |
The invention relates to compounds of formula (I): where R1 = an aryl, heteroaryl or alkyl group, optionally substituted with a group of formula -(CO)-CR6R7NR8R9, where R6, R7, R8 and R9 are as defined in the description, R2 = H or optio...
|
|
WO/2003/070694A2 |
The invention concerns a method for treating an imide organic solution bearing a sulphonyl group. Said method is designed for treatment of an impure ammonium imide composition, whereby one of the substituents of the imide is a sulphonyl ...
|
|
WO/2003/070681A1 |
A process for the production of metal salts of radical-polymerizable compounds having lowered water contents, characterized by heating (A) an aqueous solution of a salt of acrylic or methacrylic acid with an alkali or alkaline earth meta...
|
|
WO/2003/064380A1 |
Trifluoromethylbenzenesulfonyl chlorides represented by the general formula (3): (3) [wherein X and Y are each independently hydrogen or halogeno] are produced by reacting a benzotrifluoride represented by the general formula (1): (1) [w...
|
|
WO/2003/061643A1 |
The invention relates to pharmaceutical compositions comprising active glimepiride and metformin substances or the salts thereof, such as hydrochloride, succinate, fumarate, etc., which are used to control blood glucose in patients with ...
|
|
WO/2003/062212A1 |
This application relates to monomers of general formula (I) for the preparation of PNA (peptide nucleic acid) oligomers and provides method for the synthesis of both predefined sequence PNA oligomers and random sequence PNA oligomers: wh...
|
|
WO/2003/059869A1 |
A process for easily and industrially advantageously producing a high-purity 2-aralkyl-3-acetylthiopropionic acid and a high-purity 2-aralkylpropionic acid having a leaving group in the 3-position from easily available compounds. A 2-ara...
|
|
WO/2003/057665A1 |
A process for producing high-purity crystals which comprises using a polar solvent as a good solvent (e.g., an alcohol or an alcohol/water mixed solvent) and water as a poor solvent to crystallize the benzenesulfonamide derivative repres...
|
|
WO/2003/053561A2 |
A process for the preparation of nanoscale particulate material is described comprising: (i) combining one or more functional material to be precipitated as nanoscale particles and one or more surface active material in a compressed CO2 ...
|
|
WO/2003/053992A2 |
This invention describes a safe method for the production of sulfamoyl chloride from chlorosulfonyl isocyanate and formic acid in the presence of a amide catalyst, taming the hazardous nature of this reaction by circumventing heat accumu...
|
|
WO/2003/053918A2 |
The invention relates to a method for producing perfluoroalkane sulfonic acid esters and their subsequent conversion into salts, in addition to the use of the produced compounds in electrolytes and batteries, capacitors, supercapacitors ...
|
|
WO/2003/053919A1 |
The present invention relates to compounds of formula (I) wherein A?1¿, A?2¿, A?3¿, A?4¿, A?5¿, A?6¿, A?7¿, A?8¿, A?9¿, A?10¿, U, V, W, m, n and p are as defined in the description and claims, and pharmaceutically acceptable sa...
|
|
WO/2003/051894A1 |
Provided is a method for preparation of non-halide based ionic liquids, comprising reacting a halide salt of an organic cation with a Bronsted acid in the presence of an alcohol or alkene or alkyne. The non-halide based ionic liquid prod...
|
|
WO/2003/051825A1 |
The present invention provides compounds useful for inhibiting the ADAM-10 protein. Such compounds are useful in the in vitro study of the role of ADAM-10 (and its inhibition) in biological processes. The present invention also comprises...
|
|
WO/2003/051841A2 |
Carbamates and related compounds of formula R1 R2NCO-Y or R1 R2NCS-Y wherein R1 and R2 are hydrogen, alkyl, aryl, heteroaryl or may together form a piperidine, piperazine, morpholine or other heterocyclic ring, are inhibitors of hormone ...
|
|
WO/2003/051865A1 |
The invention relates to 1,3,2-dioxathian-2-ones with an exocyclic double bond in the 5-position as in formula (I), a method for production of said dioxathianones and use thereof as synthetic component for the production of compounds of ...
|
|
WO/2003/051842A2 |
Carbamates and related compounds of formula R1R2NCO-Y or R1R2NCS-Y wherein R1 and R2 may form a ring, are inhibitors of hormone sensitive lipase and are useful for the treatment of any disorder where it is desirable to modulate the plasm...
|
|
WO/2003/049698A2 |
Compounds useful as inhibitors of cyclooxygenase-2 activity have the formulae (I) or (Ia) as defined herein. In addition, Figure 2 compares the growth inhibitory activity fo the Example 4 compound 4-bromobenzaldehyde-4-sulfamylphenylhydr...
|
|
WO/2003/048116A2 |
The present invention relates to novel antidiabetic, hypolipidemic, antiobesity and hypocholesterolemic compounds of formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their phar...
|
|
WO/2003/046197A1 |
The invention relates to simple and efficient preparation of optically active 7−substituted−2−aminotetralins with industrial advantage. A process for preparation of optically active 7− substituted−2−aminotetralins or salts th...
|
|
WO/2003/046014A1 |
The invention concerns a method for sulphonation of a compound having one or several free hydroxyl functions and/or one or several substituted or unsubstituted primary or secondary amine functions. The invention is characterized in that ...
|
|
WO/2003/045878A2 |
2,$g(v)-Diaminocarboxylic acid compounds of formula (I), where X, X?1¿, Ar?$g(v)¿, Ar?2¿ and Y are as defined in claim 1, and their use as herbicides, are described.
|
|
WO/2003/045896A1 |
The present invention relates to a new process for the preparation of the ($i(S))-naproxen 4-nitrooxybutyl ester and to new intermediates obtained and used therein. The invention further relates to the use of the new intermediates for th...
|
|
WO/2003/040087A1 |
A process for the preparation of 2-[alkyl(aryl)]sulfonylbenzene sulfonyl chlorides of the formula (I), in which R is alkyl or aryl substituted at the ortho or meta positions with alkyl, aryl, NHAc or alkoxy, comprising the steps of: a) r...
|
|
WO/2003/040382A1 |
A process for easily producing from an inexpensive material various kinds of optically active chroman derivatives useful as intermediates for medicines, etc. A cyclic hemiacetal (1) obtained from dihydrocoumarin through one step is conve...
|
|
WO/2003/037851A1 |
Racemic tamsulosin free base is obtained in solid form. The solid form can be formed by precipitating racemic tamsulosin free base from a solvent that comprises at least one of water or a lower alcohol. The crystalline free base exhibits...
|
|
WO/2003/037850A1 |
Optically impure tamsulosin including racemic tamsulosin can be resolved into optically pure (R)- or (S)-tamsulosin by the use of diastereomeric sulfonate salts of tamsulosin in a fractional crystallization technique.
|
|
WO/2003/035608A1 |
The compound of formula (I) is obtained via reaction of a compound of formula (III), or (VII), with a compound of formula (IV).
|
|
WO/2003/035013A1 |
An aqueous one−pack self−etching and self−priming dental adhesive composition having a pH of at most 2, which comprises: (i) a polymerizable N−substituted alkylacrylic or acrylic acid amide monomer which optionally contains an in...
|
|
WO/2003/035611A1 |
A method is provided for making aromatic-imide and aromatic-methylidynetrissulfonyl species by reaction of aromatic species with a reactant according to formula (I): (X-SO¿2?-)¿m?-QH-(-SO¿2?-R¿1?)¿n? wherein Q is C or N; wherein eac...
|
|
WO/2003/033459A1 |
The invention concerns a method for producing arylsulphonic acid isocyanates by reacting an arylsulphonamide with a phosgene in the presence of an alkylisocyanate in a catalytically active amount.
|
|
WO/2003/033461A1 |
The invention relates to intermediate products and a novel method for producing benzocycloheptene C. The inventive method for producing the novel intermediate products of said compound is based on cost-effective starting materials, produ...
|
|
WO/2003/032970A1 |
Compounds of formula (I) or pharmaceutically acceptable salts or solvates thereof, and their use as pharmaceuticals, particularly as p38 kinase inhibitors.
|
|
WO/2003/033460A1 |
A novel, storage-stable, free-flowing, solid product consisting essentially of an alkyl benzene sulphonic acid having 1 to 4 aliphatic carbon atoms and from 7 to 11 % water based on the weight of the product, said alkyl benzene sulphonic...
|
|
WO/2003/031404A2 |
Provided are compounds, processes and synthetic intermediates useful for the preparation of compounds of the formula I and IX wherein R1 is selected from the group consisting of hydrogen, trihalomethyl, C1-C6 alkyl and substituted or uns...
|
|
WO/2003/029230A1 |
The present disclosure provides a method for the preparation of aromatic sulfonyl halides by contacting a substituted phenyl compound with a halosulfonic acid and trifluoroacetic acid. The present disclosure further provides a method for...
|
|
WO/2003/027063A1 |
A process for the preparation of sulphonated phenols of general formula (I) where R¿1? is hydrogen, a C¿1?-C¿20? alkyl group which is unsubstituted or substituted by halogen, cyano, hydroxyl, C¿1?-C¿20? alkoxy, C¿2?-C¿20? alkoxyca...
|
|
WO/2003/020691A1 |
The invention relates to the alkalimetal salts, tetraalkyl ammonium salts and phosphonium salts of heptafluoro-2-propane sulfonates, said salts being suitable for use in electronic technology, for example as support electrolytes for batt...
|
|
WO/2003/020684A1 |
The present invention describes immobilized haloenamine reagents, immobilized tertiary amides, methods for their preparation, and methods of use.
|
|
WO/2003/018552A2 |
The present invention is directed to protected amino acid halide monomers and oligomers, and to their use in the efficient sythesis of polyamides. The present invention is further directed to the use of -haloenamine reagents, which may o...
|
|
WO/2003/016285A1 |
The invention relates to a method of preparing 4-(imidazole-1-il) benzenesulphonamide derivatives having formula (I), wherein R?1¿ represents an optionally substituted aryl or heteroaryl group. The inventive method is characterised in t...
|
|
WO/2003/016249A1 |
A process for producing branched olefins from a mixed linear olefin/paraffin isomerisation feed comprising linear olefins having at least 7 carbon atoms in 5-50%w comprising in a first stage skeletally isomerising linear olefins in the i...
|
|
WO/2003/016246A1 |
A method of effecting a nucleophilic substitution of an alcohol to produce a target product includes the steps of: reacting the alcohol and a nucleophile with an azodicarboxylate and a phosphine. At least one of the azodicarboxylate and ...
|
|
WO/2003/014070A1 |
This invention relates new and improved processes for the preparation of arylalkylsulfonic acids derived from aromatic or substituted aromatic molecules and AOS acid (generally a mixture of alkenesulfonic acid and sultones, produced from...
|
|
WO/2003/014056A1 |
A process for efficiently producing an optically active 2−bromocarboxylic acid and optically active 2−sulfonyloxycarboxylic acid which are important for producing medicines, etc. An optically active 2−sulfonyloxycarboxylic ester is...
|
|
WO/2003/010128A2 |
Perfluoroalkyl-substituted amines, acids, amino acids and thioether acid compounds containing a perfluoroalkyl-iodoalkyl or perfluoroalkyl-alkene group as well as derivatives thereof, are described. They are useful as surfactants in a va...
|
|
WO/2003/010136A1 |
Organometallic complexes characterized by being represented by the general formula (1), which can be advantageously used in the systems of synthesis of carboxylic esters from aldehydes, e.g., Tishchenko’s reaction: (1) wherein M is a m...
|
|
WO/2003/006563A1 |
An imaging composition comprising a mixture of a fluid and a functional material; wherein the fluid is compressed and the functional material is dispersed and/or solubilized in the compressed fluid; and wherein the mixture is thermodynam...
|
|
WO/2003/003115A1 |
A process for purifying p-phenylenediamine color developers in their free-base form. The process includes subjecting a solution containing p-phenylenediamine-type free base color developer to short path distillation which includes at lea...
|
