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WO/2006/137774A1 |
There is provided a process for the preparation of a compound of formula I, which process comprises: (a) reaction of a compound of formula II, HO-D-NH2 II with a compound of formula III, followed by (b) reaction of the intermediate of fo...
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WO/2006/134212A2 |
The invention relates to a process for the production of tamsulosin hydrochloride crystals where the crystal size distribution is controlled by controlling the temperature where hydrochloric acid is added to the reaction mixture.
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WO/2006/131757A1 |
The present invention relates to a process for preparing certain sulphonamide intermediates useful in the preparation of HIV inhibitors and to the crystal forms thereof.
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WO/2006/133330A1 |
Hydrofluoroalkanesulfonates of the general formula R-O-CXH-CX2-SO3M, where R is selected from the group consisting of alkyl groups, functionalized alkyl groups, and alkenyl groups; X is selected from the group consisting of hydrogen and ...
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WO/2006/133331A1 |
A process for manufacture of hydrofluoroalkanesulfonic acid with at least one hydrogen bonded to the carbon atom adjacent to the carbon atom bonded to the sulfonic acid group comprising: contacting a fluoroolefin with sulfite in an aqueo...
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WO/2006/127184A1 |
The present invention is directed to a process for the preparation of sulphonylimine derivatives [particularly those of formula (XII)] and sulphamide derivatives [particularly those of formula (I)]. The process comprises reacting an alde...
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WO/2006/120816A1 |
A process in which a functional molecule capable of ionic dissociation which is stable not only chemically but also thermally under operating conditions required for electrochemical apparatus, such as fuel cells, being suitable for use a...
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WO/2006/117662A2 |
The invention relates to processes for the preparation of polymorphic forms of (R)-(-)- tamsulosin. More particularly, it relates to the preparation of polymorphic forms of (R)-(-)- tamsulosin designated as Form I and II. The invention a...
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WO/2006/109570A1 |
Disclosed is a method for commercially advantageously producing 2-isopropenyl-5-methyl-4-hexen-1-yl 3-methyl-2-butenoate with high yield. Specifically disclosed is a method for producing 2-isopropenyl-5-methyl-4-hexen-1-yl 3-methyl-2-but...
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WO/2006/108883A1 |
The present invention relates to a method for preparing a highly soluble linear alkyl benzene sulphonate (LAS). Specifically, the method includes adding a hydrotropic composition before or after the sulphonation of the linear alkyl benze...
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WO/2006/106800A1 |
Disclosed is a method for producing a compound (III), a salt thereof or a solvate of them by reacting a compound (I), a salt thereof or a solvate of them with a compound (II) in a toluene solvent in the presence of an additive such as wa...
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WO/2006/106960A1 |
A disulfonyl fluoride compound is easily and efficiently produced through a coupling reaction. The compound is converted to produce a useful compound. A compound (1) in which Y is fluorine is subjected to a photocoupling reaction, while ...
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WO/2006/106244A2 |
The invention relates to a method for preparing a compound of formula (I) in which: R1, R2, R3, while being identical or different, are protective groups and Nu is a nucleophilic group, to a method in which a nucleophilic compound is rea...
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WO/2006/087166A1 |
Provided is a process for the preparation of N-monosubstituted β-aminoalcohol sulfonates of formula (Ia), (Ib) wherein R1 is C6-20 aryl or C4-12 heteroaryl, each optionally being substituted with one or more halogen atoms and/or one or ...
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WO/2006/072259A2 |
The quantitatively most important pathway for the excretion of cholesterol in mammals is the formation of bile salts (the conjugate bases of bile acids). The major bile salts are synthesized and secreted by as glycine or taurine conjugat...
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WO/2006/061549A1 |
A process for producing tamsulosin of formula (I) and pharmaceutically acceptable addition salts, thereof comprises the steps of : a) Reacting compound R,R-[2-(4-methoxy-phenyl)-1-methyl-ethyl]-(1-phenyl-ethyl)-a
mine of formula (II) or ...
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WO/2006/059700A1 |
Disclosed is a separating agent for asymmetric substances which has high separation performance. Specifically disclosed is a polysulfonamide derivative represented by the following formula (1) or (2). (In the formulae, R represents an op...
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WO/2006/051697A1 |
Disclosed is a method for producing a fluorine-containing fluorosulfonyl alkylvinyl ether represented by the following chemical formula: CF2=CFOCF2CF2SO2F which is characterized in that a fluorine-containing chlorosulfonyl alkylvinyl eth...
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WO/2006/052522A2 |
Disclosed are methods for making the phosphonium sulfonate salt of generic formula: (1): wherein each X is independently a halogen or hydrogen, provided that the molar ratio of halogen to hydrogen is greater than about 0.90; p is 0 or 1 ...
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WO/2006/042678A1 |
The invention relates to a method for cleaning 3-hydroxyamidinophenylalanine derivatives comprising the steps: (a) addition of an aromatic sulphonic acid to a solution of an optionally contaminated 3-hydroxyamidinophenylalanine derivativ...
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WO/2006/040131A1 |
The invention relates to a method for combining carbon-carbon bonds starting from a copper compound of an aryl, heteroaryl, alkene or alkine and an aryl, heteroaryl, alkene or alkine compound with a suitable nucleofuge. The copper compou...
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WO/2006/023611A1 |
The present invention provides method for making a compound of formula (1) comprising the steps of reacting compounds of formulas (2) and (3) to produce a compound of formula (4) wherein R1, R2, R3, R4 and R5 are defined as described her...
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WO/2006/019358A2 |
The present invention relates to a process for preparing Tamsulosin, an anti-benign prostatic hyperplasia drug, which comprises converting o-ethoxyphenoxyethanol to a corresponding sulfonate, and reacting the sulfonate with (R)-(-)-5-(2-...
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WO/2006/006156A2 |
The invention provides methods for detection of medical disorders, associated with cellular oxidative stress, cell degeneration and / or cell death. The invention further relates to compounds comprising a thiol (-SH) group, for detecting...
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WO/2006/004093A1 |
A process for industrially advantageously producing tamsulosin or a pharmacologically acceptable salt thereof, which are useful as a therapeutic agent for urination disorders accompanying prostatic hypertrophy. The process, which is for ...
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WO/2006/003795A1 |
A process which comprises using a stable Ru(salen)(CO) complex represented by the general formula (I) or an enantiomer thereof as the catalyst and by which optically active aziridines and amines can be produced enantioselectively with a ...
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WO/2005/123646A2 |
The production of fluoroorganic compounds in the form of amidoamines, quaternised compounds thereof, amides and ethers, guanidides, hydrazides, ureides, thioureides, perfluoropolyoxaalkylenesulfo- or perfluoropolyoxaalkylenecarboxylic ac...
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WO/2005/118529A2 |
This invention relates to a process for preparing optically active &agr -amino acid substrates which are used to make potent lethal factor (LF) inhibitors for the treatment of anthrax. This invention further relates to a process for synt...
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WO/2005/105737A1 |
The present invention relates to novel processes for the preparation of substituted tetralin and substituted indane derivatives. The present invention is further directed to novel processes for the preparation of intermediates in the pre...
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WO/2005/102993A1 |
A process for the purification of aqueous acid solutions which can dispense with the step of removing chloride ions and which is reduced in the damage to an ion exchanger (such as an ion-exchange column) and thereby permits repeated use ...
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WO/2005/100307A2 |
A method for making the phosphonium sulfonate salt of generic formula (1): wherein each X is independently a halogen or hydrogen, provided that the molar ratio of halogen to hydrogen is greater than about 0.90; p is 0 or 1 and q and r ar...
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WO/2005/095323A1 |
La présente invention concerne un procédé de préparation de composé ester activateur de blanchiment. Ce procédé consiste (A) à préparer un monoester d'acide gras, (B) à fabriquer un chloroformate par réaction de ce monoester d...
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WO/2005/092952A1 |
A process for sulfating alkoxylated amines, alkoxylated polyols, hydrophobic polyamine ethoxylate polymers, via the use of sulfuric acid.
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WO/2005/085187A1 |
Disclosed is a method for producing an &ohgr -fluorosulfonyl perfluoroalkyl vinyl ether represented by the general formula (2) below through specific steps (a)-(c) from an &ohgr -haloperfluoroalkyl sulfonyl fluoride represented by the ge...
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WO/2005/081777A2 |
Severely sterically hindered secondary aminoether alcohols are prepared by reacting an organic carboxylic acid or alkali metal salt of an organic carboxylic acid with a sulfonyl halide, a sulfuryl halide, a mixed sulfuryl ester halide or...
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WO/2005/082843A1 |
The present invention provides processes for the preparation of arylalkylsulfonyl halides and heteroarylalkylsufonyl halides of Formula: Ar-R-SO2-X, that are useful as intermediates in the preparation of pharmaceuticals.
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WO/2005/080323A1 |
The invention relates to an improved process for the manufacture of enantiomerically pure R-(+) or S-(+)-5-(2-aminopropyl)-2-methoxybenzene sulfonamide by resolution of (R,S)-5-(2-aminopropyl)-2-methoxybenzene sulfonamide with D-(-) or L...
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WO/2005/075416A1 |
In the present invention, amorphous tamsulosin hydrochloride, the process for preparation thereof by lyophilisation or spray-drying and the properties thereof are disclosed. Amorphous tamsulosin hydrochloride is useful in the preparation...
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WO/2005/075406A1 |
An adamantane derivative (I) having a structure represented by the general formula (I); an adamantane derivative (II) having a structure represented by the general formula (II); and a process for producing these adamantane derivatives. A...
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WO/2005/075073A1 |
The present invention is to provide a recyclable water-soluble transition metal complex catalyst which is a novel metal complex catalyst capable of producing an optically active alcohol from a ketone with good yield and good optical puri...
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WO/2005/075623A1 |
The present invention provides acylalkylisethionate esters useful in consumer products. The acylalkylisethionate esters are produced by reacting one or more carboxylic acids with one or more alkyl-substituted hydroxyalkyl sulfonates unde...
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WO/2005/075651A1 |
A low-cost and efficient industrial process for producing (S)-2-pentanol, (S)-2-hexanol, 1-methylalkylmalonic acid and 3-methylcarboxylic acid with high optical purity. There is provided a process for producing (S)-2-pentanol and (S)-2-h...
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WO/2005/075415A1 |
A method of preparation of (R)-(-)-5-(2-aminopropyl)-2-methoxybenzenesulfonamide of formula I and its use for production tamsulosin. A protective group is introduced to N-[(1R)-2(4-methoxyphenyl)-1-methylethyl]-N- [(1 R)-1-phenylethyl)...
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WO/2005/073182A1 |
A method for producing a fluorine-containing unsaturated sulfonyl fluoride represented by the chemical formula: RfSO2F (wherein Rf is as defined below) is characterized in that a fluorine-containing unsaturated sulfonyl chloride represen...
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WO/2005/073388A1 |
A process for producing an optically active 1,4-pentanediol which comprises asymmetrically reducing 5-hydroxy-2-pentanone, which is easily available at low cost. Also provided is a process for producing an optically active 1-substituted ...
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WO/2005/069751A2 |
Radicals with unpaired electrons are used to initiate a chain reaction that converts small hydrocarbons such as methane into oxygenated liquids. An initiator such as Marshall's acid is used to create methyl radicals. These radicals combi...
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WO/2005/068405A1 |
A process for producing phenyl-alkanes by paraffin dehydrogenation followed by olefin isomerization and then by alkylation of a phenyl compound by a lightly branched olefin is disclosed. An effluent of the alkylation section comprises pa...
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WO/2005/065164A2 |
A process for preparing fluorochemical monoisocyanates comprises reacting at least one fluorochemical alcohol represented by the formula CnF2n+1SO2NCH3 (CH2) mOH, wherein n = 2 to 5, and m = 2 to 4, with 4,4' -diphenylmethane diisocyanat...
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WO/2005/063700A1 |
The invention relates to a process for catalyzing the preparation of directly esterified fatty acid isethionate (DEFI) reaction using group 4 metal based catalyst (according to IUPAC). Directly esterified fatty acyl isethionate (DEFI) is...
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WO/2005/063701A1 |
The present invention relates to a new process for the preparation of optically pure (R)-5-(2-aminopropyl)-2-methoxybenzenesulphonamide, which is an intermediate in the synthesis of tamsulosin.
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