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JP4197312B2 |
The present invention relates to a new microbial process for the preparation of compound formula (I) from a compound of general formula (II) wherein R stands for an alkali metal or ammonium ion, by the submerged cultivation of a mold str...
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JP4186819B2 |
Manufacture of a fluorine-containing norbornene derivative having a fluorine-containing ketone structure comprises reacting a norbornene derivative and a fluoroalkylating agent. Manufacture of a fluorine-containing norbornene derivative ...
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JP2008540681A |
A process is provided for producing an enriched carboxylic acid compositions produced by contacting composition comprising a carboxylic acid with an enrichment feed in an enrichment zone to form an enriched carboxylic acid composition. T...
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JP4182300B2 |
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JP4182284B2 |
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JP2008201719A |
To solve the problem of a low reaction speed in the hydrolysis of tetracarboxylic acid tetraester associated with a prior art technique, and to provide an efficient method for preparing a tetracarboxylic acid and a method for preparing a...
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JP2008195657A |
To provide new uses of (R)-2-hydroxy-2'-alkoxy-1,1'-binaphthalene and (S)-2-hydroxy-2'-alkoxy-1,1'-binaphthalene.A cyclopropanecarboxylic acid can be easily put to optical resolution using (R)-2-hydroxy-2'-alkoxy-1,1'-binaphthalene repre...
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JP4121858B2 |
The compounds of the instant invention are bicyclic or tricyclic amino acids useful in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain, arthritis...
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JP4118269B2 |
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JP4110861B2 |
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JP4093882B2 |
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JP4080890B2 |
The present invention is a process for the preparation of a compound of formulaThe compounds of formula I are valuable intermediates for the manufacture of therapeutically active compounds.
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JPWO2005123650A1 |
To provide a novel fluorinated adamantane derivative. Equation AF(-COF)nThe compound represented by. However, AF, And N have the following meanings. AF: N-valent group of adamantan with n hydrogen atoms removed (where n is 2 or more, the...
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JP2008509908A |
A method for preparing a product of a chemical reaction includes conducting the chemical reaction in a solvent medium of one or more liquid nonionic surfactant(s). The liquid nonionic surfactants preferably are CmEn type poly(alkylene ox...
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JP2008507498A |
Compounds of formula I are useful in treatment of diseases associated with the deposition of beta-amyloid in the brain.
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JP4048759B2 |
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JP4020425B2 |
Prepn. of enantiomerically pure cyclopentane- or cyclopentene- beta -aminoacids of formula (I) comprises:(a) converting a meso-cyclopentane- or cyclopentene dicarboxylic anhydride of formula (II) into an enantiomerically pure monoester o...
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JP4014008B2 |
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JP4013005B2 |
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JP2007302727A |
To provide a new inclusion material and an inclusion method. The inclusion material contains a host molecule having an inclusion action to a guest molecule. The host molecule is a cyclic polymethacrylic acid oligomer. The guest molecule ...
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JPWO2005027892A1 |
The present invention is an insulin early secretion promoter composed of corosolic acid and the like. According to the insulin early secretion promoter of the present invention, it is possible to provide an insulin early secretion promot...
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JPWO2005027891A1 |
Provided is an insulin early secretagogue comprising a triterpene represented by the following general formula (1) and / or a triterpene represented by the following general formula (2).[In the formula, R1Is a COOH group, etc., R11And R1...
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JP2007269721A |
To provide a method by which a biadamantanecarboxylic acid derivative can simply be produced from a readily available compound in high yield and selectivity. A biadamantane derivative having at least one group eliminable with an acid and...
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JP3985603B2 |
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JP2007238460A |
To provide a method for producing a cyclobutane-1,2,3,4-tetracarboxylic acid compound in high selectivity, enabling the reaction by dispersing in water completely without using an organic solvent as a reaction medium while keeping extrem...
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JP3973559B2 |
Compounds and compositions comprising specific metal salts of bicyclo[2.2.1]heptane dicarboxylate salts in order to provide highly desirable properties within polyolefin articles are provided. The inventive salts and derivatives thereof ...
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JP3961827B2 |
This invention relates to new RAR selective retinoid agonists of formula I wherein the symbols are as defined in the specification to their pharmaceutically acceptable salts, individual isomers or to a racemic or non-racemic mixture; to ...
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JP2007204471A |
To provide a method for producing bicyclo[4.3.0]nonane-3(4), 7(8)-dicarboxylic acid from bicyclo[4.3.0]nona-3,7-diene. In the production method, bicyclo[4.3.0]nona-3,7-diene is reacted with a synthesis gas at 70-160°C under pressure of ...
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JP3927232B2 |
Terpene-quinones with antitumour activity, defined from a Diels-Alder cyclocondensation reaction, thereby achieving families or series of said compounds of new structure which have cytotoxic activity against cell cultures P-388, A-549, H...
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JP2007513870A |
This patent discloses a substituted fullerenes, compositions comprising the same, and their use as antioxidants. The substituted fullerenes comprise a fullerene core (Cn) and at least one of: (i) from 1 to 6 (>CX1X2) groups bonded to the...
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JP3904854B2 |
To provide a method for producing a fluorine-containing alicyclic dicarboxylic acid compound useful in a field of an electronic material, i.e., a low dielectric package material for a semiconductor and a substrate material, an optical ma...
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JP2007502815A |
The present invention is directed to a compound of formula I, or a pharmaceutically acceptable salt, solvate, hydrate or stereoisomer thereof, which is useful in treating or preventing disorders mediated by a peroxisome proliferator acti...
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JP3879886B2 |
To produce the subject compound utilzable as an optical material excellent in heat and moisture resistances and transparency and useful as an additive for general-purpose resins, various structural material resins, etc., by hydrolyzing a...
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JP3869166B2 |
To obtain a new compound of a polyalicyclic derivative containing oxygen or sulfur in the cyclic compound, and having hydroxy group, excellent in etching resistance and useful for a photoresist. This new compound is a photoresist monomer...
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JP3858666B2 |
To provide a method for economically purifying crude CHDA. Impurities are removed by sublimation by means of heating under an inert gas atmosphere the crude 1,4-cyclohexanedicarboxylic acid obtained in the step to hydrogenate terephthali...
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JP3847579B2 |
To provide a new alicyclic fluorine-containing dicarboxylic acid or its derivative, further a polymer by using the above alicyclic fluorine-containing dicarboxylic acid and an acid-instable compound for achieving a low dielectric propert...
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JP3839130B2 |
To obtain the subject soap useful an adhesive for radial tire, a curing promoter for coating compound, etc., in high yield, by heating a mixture a fatty acid having dissolved a molybdenum soap and a metal compound. (A) A fatty acid havin...
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JP3839256B2 |
The present invention relates to novel amidino compounds of formula (I),or a salt, solvate, or physiologically functional derivative thereof;wherein R1 is selected from C1-4 alkyl, C3-4 cycloalkyl, C1-4 hydroxyalkyl, and C1-4 haloalkyl; ...
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JP3836777B2 |
To provide a method for producing an intermediate for synthesizing an antifungal compound. The method includes a method for producing 2- fluorocyclopropanecarboxylic acid by debrominating 2-bromo-2- fluorocyclopropanecarboxylic acid; or ...
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JP3836508B2 |
Halogenated compounds are prepared by ring opening reactions of highly fluorinated cyclopropanes with chlorine, bromine, iodine, or mixtures thereof at temperatures over 100 DEG C. A novel compound, which is one type of compound produced...
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JP2006523671A |
Alpha substituted carboxylic acids of formula (I): wherein R' and R2 are as defined in the specification and R3 is A) formula (II); B) formula (III); C) formula (IV); and D) formula (V); wherein Y, Art, Are, AP, R4, R5, R6, R7, R6, R9, R...
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JP2006282664A |
To provide a method for hydrolyzing a cyclopropane carboxylic ester to a free acid.A methyl cyclopropane carboxylate or ethyl cyclopropane carboxylate 1 is hydrolyzed by the mixing with suitably one or more kinds of alcohols 2 and water ...
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JPWO2005012221A1 |
In the present invention, the general formulas (I) and (I) (in the formula, ring A, ring B and ring D each represent a cyclic group which may have a substituent independently, and W is the number of atoms in the main chain. 1 to 8 spacer...
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JP2006225290A |
To provide an industrially advantageous method for producing a highly pure alicyclic monoolefin carboxylic acid with a reduced amount of impurities.The alicyclic monoolefin carboxylic acid of formula (1) (wherein R1 is a hydrogen atom or...
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JP2006518729A |
A process for the preparation of gamma-cyhalothrin comprising steps of a) chlorinating 1R cis-Z 3-(2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethyl cyclopropanecarboxylic acid to give 1R cis-Z 3-(2-chloro-3,3,3-trifluoro-1-propenyl)-2,2...
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JP2006518760A |
Disclosed and claimed herein are e,e,e malonic acid/acetic acid tri-adducts of buckminsteriullerene of the general formula C 60 R 3 , wherein each R is independently selected from the groups of formula -CR 1 R 2 wherein each R 1 and R 2 ...
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JP2006518341A |
A compound having the following formula (I): wherein R1 is N-containing heterocyclic ring optionally substituted with one or more suitable substituent(s), R2 is hydroxyamino, R3 is hydrogen or a suitable substituent, L1 is -(CH2)n- (wher...
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JP2006518335A |
The disclosed invention refers to a process for obtaining fatty acid alkyl esters, rosin acids and sterols from crude tall oil (CTO), which is characterized by the following steps: (a) reacting the free fatty acids present in the CTO wit...
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JP3807605B2 |
To provide a compound capable of being utilized as an intermediate for producing a cyclopropane carboxylate ester which is an insecticidally active compound known as pyrethroids, and being observable because of having very good insectici...
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JP3805510B2 |
To produce a cyclopropylacetylene derivative useful as a synthetic intermediate of a benzoxazinone derivative, etc., having anti-HIV activities under a mild condition by an industrially advantageous production method. A compound of formu...
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