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WO/2024/055820A1 |
Disclosed herein are a spirodihydroindene skeleton-based chiral amine-squaramide compound, a method for preparing same, and use thereof. The chiral amine-squaramide compound is an enantiomeric compound with a structure represented by gen...
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WO/2023/143112A1 |
Disclosed are a salt form and a crystal form of an azabenzo eight-membered ring compound and an application thereof. Specifically disclosed are a crystal form A, crystal form B, crystal form C, and crystal form D of fumarate salt, hydroc...
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WO/2023/107648A2 |
Provided herein are compounds, such as compounds of Formula (I), and pharmaceutically acceptable salts, hydrates, solvates, polymorphs, co-crystals, tautomers, stereoisomers, and isotopically labeled derivatives thereof, and compositions...
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WO/2023/083895A1 |
The invention relates in a first aspect to an azadibenzocyclooctyne derivative according to formula (I) or a salt thereof having specific substituents at the benzo rings of the DIBAC structure and having specific substituents connected t...
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WO/2023/025276A1 |
Disclosed in the present invention is a compound having a structure shown in general formula I, or a stereoisomer thereof, a pharmaceutically acceptable salt thereof, or a solvate thereof. Further disclosed in the present invention are a...
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WO/2023/019148A1 |
Provided are enrichment methods. The methods may be used to enrich macromolecules. The enrichment may be performed with a multifunctional molecule. The multifunctional molecule may include any combination of a delivery moiety, a reactive...
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WO/2023/004382A1 |
In one aspect, the disclosure relates to a scaffold for a class of small molecules that selectively inhibit the α3β4 nicotinic acetylcholine receptor (nAChR) subtype, as well as molecules constructed using the scaffold and syntheses th...
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WO/2022/247914A1 |
Provided are a quaternary ammonium salt compound, a preparation method therefor and a use thereof. The compound represented by general formula (I), or an isomer or pharmaceutically acceptable salt thereof, and a composition thereof can b...
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WO/2022/218391A1 |
The present invention relates to a chiral spiro ammonium salt compound, and a preparation method therefor and an application thereof. Specifically, the compound has the following optical pure or racemic compound represented by structural...
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WO/2022/162014A1 |
The present invention concerns aza-cryptophanes, processes for preparation thereof, and their uses, in particular as in vivo diagnostic tools when complexing a hyperpolarized noble element, or in nanoemulsions.
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WO/2022/158872A1 |
The present invention relates to a purification method for laurolactam, and more specifically, to a purification method capable of obtaining high-purity laurolactam substantially free of impurities. The present invention provides a metho...
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WO/2022/124861A1 |
The present invention relates to a laurolactam preparation method, a synthesizing device therefor, a laurolactam composition prepared thereby, and a polylaurolactam preparation method using the laurolactam composition, the laurolactam pr...
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WO/2022/120226A1 |
The present disclosure provides methods and related compositions that incorporate a molecularly targeted approach via the integrin subtype αvβ6 using Peptide Receptor Radionuclide Therapy (PRRT) and a theranostic approach.
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WO/2022/101363A1 |
This invention relates to novel surface modified viral capsids and recombinant virions comprising the same. Furthermore, this invention concerns intermediates for the preparation of surface modified viral capsids. The surface modified vi...
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WO/2022/100696A1 |
Disclosed in the present application are a multi-specific bioconjugate linker and a synthetic method therefor, and specifically, a compound or a tautomer, a mesomer, a racemate, an enantiomer, or a diastereoisomer thereof, or a mixture t...
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WO/2022/058291A1 |
The invention relates to an improved process for the acid hydrolysis of polylaurolactam with sulfuric acid. An especially suitable starting material is polylaurolactam which is intended for recycling and which is characterized by a low l...
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WO/2022/037590A1 |
The present invention relates to the field of medical chemistry and provides a quaternary ammonium salt compound for anesthesia, a preparation method therefor, and use thereof. The quaternary ammonium salt compound is a compound as repre...
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WO/2021/122249A1 |
Process to produce N-vinyl compounds by homogeneous catalysis, wherein acetylene is reacted with a cyclic compound comprising a cyclic compound having at least one nitrogen as ring member, bearing a substitutable hydrogen residue (cyclic...
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WO/2021/112407A1 |
The present invention relates: a method for producing laurolactam, the method comprising a) a step for synthesizing cyclododecanone oxime into laurolactam through Bechmann rearrangement in a catalytic system, b) a step for mixing the lau...
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WO/2021/009232A1 |
The present invention relates to compounds of Formula (I), (I) wherein R1, R2, R3 and R4 are as defined herein. The invention further relates to herbicidal compositions which comprise a compound of Formula (I), to their use for controlli...
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WO/2020/259620A1 |
A series of compounds having heterocyclo alkyl structures, isomers or pharmaceutically acceptable salts thereof, and an application thereof in preparing medicines for treatment of diseases related to CCR2/CCR5 antagonist. The present inv...
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WO/2020/193681A1 |
The present invention relates to derivatives of 10-methylene lipids, their preparation and their use.
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WO/2020/184670A1 |
The present invention relates to a method for monodeuterated lower alkylating an amine moiety of a compound which contains an amine that is protected by an aralkyl group, wherein a monodeuterated lower alkyl is introduced into the amine ...
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WO/2020/130605A1 |
The present invention relates to a laurolactam preparation method and a synthesis apparatus, and epoxidation and a rearrangement reaction are carried out in the conversion of cyclododecene into cyclododecanone so that the preparation met...
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WO/2020/055113A1 |
The present disclosure relates to an organic electroluminescent compound represented by formula 1 and an organic electroluminescent device comprising the same. By comprising the organic electroluminescent compound of the present disclosu...
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WO/2019/207246A1 |
The present invention relates to a method for olefin metathesis, which comprises placing in contact: - at least one olefin, - at least one metathesis catalyst selected from the ruthenium alkylidene complexes comprising two imidazoline-2-...
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WO/2019/154287A1 |
Disclosed are a quaternary ammonium salt compound, a preparation method therefor and a use thereof. Provided is a novel structural compound as shown in formula Ⅰ, or a pharmaceutically acceptable salt thereof, or a stereoisomer thereof...
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WO/2019/082910A1 |
Provided are: a V2 receptor antagonist which has high water solubility and which is particularly suitable for injections; and a medicine containing the V2 receptor antagonist or the like. The present invention is a compound represented b...
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WO/2019/063069A1 |
The invention relates to the use of a compound of formula (I) as described herein as an aromatic substance. The invention also relates to novel compounds of formula (I) as described herein or mixtures comprising at least one different co...
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WO/2019/029408A1 |
Provided are a streptovaricin derivative, a preparation method therefor, and an application thereof, pertaining to the field of bio-pharmaceuticals. The novel streptovaricin derivative 1-4 is obtained by using Streptomyces spectabilis XW...
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WO/2018/212216A1 |
Provided is a method for producing an optically active isomer, the method including an asymmetry induction step in which an asymmetry-inducing agent is caused to act on chiral molecules having an enantiomeric-excess half-life period less...
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WO/2018/129552A1 |
The present disclosure is directed to compounds and methods for the treatment of disorders associated with fluid retention or salt overload, such as heart failure (in particular, congestive heart failure), chronic kidney disease, end-sta...
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WO/2018/110799A1 |
Provided are a compound represented by any one of chemical formulas 1 to 3, or an isomer, derivative, solvate, or pharmaceutically acceptable salt thereof, a production method therefor, and a use thereof. According to this, antibacterial...
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WO/2018/104856A1 |
A process of obtaining a purified geometric isomer of an unsaturated macrocyclic compound is disclosed herein. The process is effected by contacting an ion exchange medium comprising silver ions with a mixture comprising at least one geo...
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WO/2018/100029A1 |
The invention relates to heterocyclic compounds, particularly for use in electronic devices. The invention further relates to a method for producing the compounds according to the invention, and to electronic devices comprising same.
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WO/2018/098390A1 |
Provided herein are compounds of Formula (I) or a pharmaceutically acceptable salt thereof, wherein L1 and L2 are each independently a covalent bond or a divalent linking group, R is a detectable label or therapeutic drug and B is an alb...
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WO/2018/039521A1 |
This invention relates to deuterated forms of cenicriviroc, racemic and (R) forms thereof, free base forms of any of the foregoing and pharmaceutically acceptable salts of the free base forms. In one aspect, the invention provides a comp...
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WO/2018/009417A1 |
Disclosed herein are small molecule calpain modulator compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to macrocyclic α-keto amide derivatives and their use as therapeutic agents.
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WO/2018/002114A1 |
The invention relates to a method for reactivating homogeneous catalyst systems from organic reaction mixtures. The catalyst systems are suitable for oxidating organic compounds such as, for example cyclododecene. The reactivation is car...
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WO/2017/156071A1 |
The present technology relates to cyclic keto-amide compounds of general formulae I to XXXII, compositions and kits thereof as calpain modulators and methods useful for the treatment of various diseases or disorders such as fibrotic dise...
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WO/2017/109178A1 |
A subject of the present invention is the use of a compound having the general formula (I): (I) wherein V, W, X4, X5, X6, X7, X'4, X'5, X'6, X'7, Y, Y', R3, R'3, R4 and R'4 are as defined in any one of claims 1 to 11, for the detection, ...
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WO/2016/100033A9 |
Methods for producing lactams from oximes by performing a Beckmann rearrangement using a hierarchical porous aluminophosphate catalyst having interconnected microporous and mesoporous networks are provided. Exemplary catalysts include a ...
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WO/2016/172795A1 |
The present invention concerns a method for the prevention and/or treatment of an activation-induced deaminase (AID)-associated disease in a subject in need thereof, said method comprising administering an effective amount of an uracil-D...
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WO/2016/149581A1 |
Provided herein are compounds of formula (I) useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.
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WO/2016/105527A1 |
The disclosure includes high purity compounds having CCR5 and/or CCR2 antagonism, or a salt thereof, and processes for synthesizing the same.
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WO/2016/059942A1 |
Provided is a three-phase AC/DC conversion device disposed between a three-phase AC power supply and a light-emitting diode group, the device comprising: a three-phase full-bridge circuit in which pairs of switching elements are connecte...
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WO/2016/056371A1 |
Provided is a photochemical reaction device characterized in that two partition walls formed from a light-transmitting material are arranged apart from each other between a light source and a reaction liquid. The photochemical reaction d...
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WO/2016/056370A1 |
Provided is a photoirradiation device equipped with: a first optically transparent container for covering a light-emitting body provided with a light-emitting diode; a liquid phase section positioned to the exterior thereof and formed fr...
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WO/2016/047882A1 |
The present invention relates to a novel one-photon or two-photon absorbing fluorescent compound, a method for preparing the same, and a cell imaging method using the same and, more specifically, to a novel two-photon absorbing fluoresce...
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WO/2015/112014A1 |
The present invention relates to a process comprising the step of reacting a (hetero)aryl 1,3-dipole compound with a (hetero)cycloalkyne, wherein: a (hetero)aryl 1,3-dipole compound is defined as a compound comprising a 1,3-dipole functi...
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