Heterocyclic Compounds

Matches 1,251 - 1,300 out of 5,408	< 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 >

Document	Document Title
WO/1994/006755A1	ALCOHOL DERIVATIVE HAVING RENIN-INHIBITING ACTIVITY AND USE THEREOF An alcohol derivative represented by general formula [1], an intermediate for producing the same, and a renin-inhibiting composition containing the same (wherein A represents (a) or (b); W represents (c), (d), (e), etc.; X represents -CO...
WO/1994/006778A1	HYDROXYL AMINO PHENYL SULPHONYL UREAS, THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS The sulphonyl ureas of formula (I) and their salts are suitable as selective herbicides to combat weeds in the cultivation of useful plants. The intermediate products of formulae (II) and (IV) may be used for their production.
WO/1994/006765A1	NITROGENOUS HETEROCYCLIC COMPOUND, PROCESS FOR PRODUCING THE SAME, AND PEST CONTROL AGENT A compound represented by general formula (I) or a salt thereof, a process for producing the same, and a pest control agent containing the same as the active ingredient efficacious against cotton aphid, green rice leafhopper and so forth...
WO/1994/006791A1	NOVEL CONDENSED THIAZOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME A condensed thiazole derivative useful as a 5-HT3 receptor agonist, represented by general formula (I), a pharmaceutically acceptable salt thereof, a process for producing the same, and a pharmaceutical composition containing the same, w...
WO/1994/005648A1	DIARYL PIPERAZINOACETAMIDE COMPOUNDS AS ANTIMUSCARINIC AGENTS Diaryl piperazineacetamide compounds useful as antimuscarinic agents for treating a variety of indications such as Parkinson's disease, motion sickness and for the inhibition of gastric acid secretion.
WO/1994/005531A1	CRANK MECHANISM FOR A WINDSCREEN WIPER DRIVE OF A MOTOR VEHICLE In a crank mechanism for a windscreen wiper drive for a motor vehicle which consists of a lever (10) and a shackle connected thereto via an articulated joint (11) in which said shackle is articulated eccentrically on a driven gear wheel,...
WO/1994/005153A1	HERBICIDAL BENZENE COMPOUNDS Herbicidal compositions and method of use involving effective amounts of substituted benzene compounds to control the growth of undesired vegetation.
WO/1994/005669A1	CATIONIC-2-HETEROARYLPHENYL-CARBAPENEM ANTIBACTERIAL AGENTS Carbapenems of formula (I) are useful antibacterial agents.
WO/1994/005660A1	QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS Compounds of formula (I) and their pharmaceutically acceptable salts in which R1 is hydrogen or hydroxy; R2 is hydrogen; or R1 and R2 are joined together so that CR1-CR2 is a double bond; X is selected from -CH2CH2-, -CH=CH-, -C=C-, -CH2...
WO/1994/004508A1	IMIDAZOLYL/BENZIMIDAZOLYL-TERMINATED ALKYLAMINO ETHYNYL ALANINE AMINO DIOL COMPOUNDS FOR TREATMENT OF HYPERTENSION Compounds characterized generally as imidazolyl/benzimidazolyl-terminated alkylamino ethynyl alanine amino diol derivatives are useful as renin inhibitors for the treatment of hypertension. Compounds of particular interest are those of f...
WO/1994/004525A1	BENZOHETEROCYCLIC COMPOUNDS AS OXYTOCIN AND VASOPRESSIN ANTAGONISTS Novel benzoheterocyclic compound of formula (1) and pharmaceutically acceptable salts thereof, which show excellent antivasopressin activity and oxytocin antagonistic activity, and are useful as a vasopressin antagonist or oxytocin antag...
WO/1994/003446A1	4-SUBSTITUTED 1,2,4-TRIAZOLE DERIVATIVES 4-substituted 1,2,4-triazole derivatives of formula (I), wherein R represents a 2-(dimethylamino)ethyl group, or a group of formula (i) or (ii) or a salt or prodrug thereof, are selective agonists of 5-HT1-like receptors and are therefor...
WO/1994/003064A1	SELECTIVE HERBICIDAL COMPOSITION A selective herbicidal composition for controlling grasses and weeds in crops of cultivated plants, comprising: (a) a herbicidally effective amount of a sulfonyl urea of formula (I) wherein R1 is hydrogen or methyl; R2 and R3 are each in...
WO/1994/002477A1	IMIDAZOLE, TRIAZOLE AND TETRAZOLE DERIVATIVES Imidazole, triazole and tetrazole derivatives of formula (I) are selective agonists of 5-HT1-like receptors and are therefore useful in the treatment of clinical conditions, in particular migraine and associated disorders, for which a se...
WO/1994/002447A1	HYDROXAMIC ACID DERIVATIVES AS METALLOPROTEINASE INHIBITORS Compounds of formula (I) have matrix metalloproteinase inhibitory activity, wherein R2 represents a group R6-A- wherein A represents a divalent straight or branched, saturated or unsaturated hydrocarbon chain of up to 6 C atoms which may...
WO/1994/002446A1	NATURAL AMINO ACID DERIVATIVES AS METALLOPROTEINASE INHIBITORS Compounds of Formula (I) wherein R2 represents a group R6-A- wherein A represents a divalent straight or branched, saturated or unsaturated hydrocarbon chain of up to 6 C atoms which may be interrupted by an O or S atom, and R6 represent...
WO/1994/002476A1	PROCESS FOR PREPARING INDOLE DERIVATIVES CONTAINING A 1,2,4-TRIAZOL-1-YL SUBSTITUENT A process for preparing tryptamine derivatives and related compounds having a 1,2,4-triazol-1-yl moiety within the molecule comprises reacting 4-amino-1,2,4-triazol with a nitrobenzene derivative containing a readily displaceable group; ...
WO/1994/001418A1	TRIAZOLYLBUTANE DERIVATIVES WITH A FUNGICIDAL ACTION Described are triazolylbutane derivatives of the formula (I), in which A may be a keto group or a CH(OH) grouping and R may be alkyl, optionally substituted cycloalkylalkyl, alkenyl, alkinyl or haloalkenyl (with the exception of 3-chloro...
WO/1994/001416A1	FUNGICIDAL TRIAZOLYLETHANOL DERIVATES New triazolylethanol derivates have the formula (I), in which a stands for a ketone group or for a CH(OH) grouping; R stands for halogen alkyl or for halogen alkenyl and R1 stands for a residue having the formula (a), in which X stands f...
WO/1994/001417A1	FUNGICIDAL TRIAZOLYL-BUTANE DERIVATES New triazolyl-butane derivates have the formula (I), in which (A) stands for a ketone group or for a CH(OH) grouping and (R) stands for ethyl, n-propyl, isopropyl, branched butyl, straight or branched chain alkyl with more than 4 carbon ...
WO/1993/025548A1	5-(1,2,4-TRIAZOL-1-YLMETHYL)-3H-ISOBENZOFURAN-1-ONE DERIVATIVES, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS This invention relates to heterocyclic compounds which are inhibitors of the enzyme aromatase, to processes for their preparation, to pharmaceutical compositions containing them and to their use in medicine. Particular compounds of the i...
WO/1993/025549A1	PROCESS FOR PREPARING 1,3-DIOXOLANE DERIVATIVES This invention provides an improved process for the preparation of compounds of formula (I), wherein n is 0, 1 or 2; each R1 is independently halo or lower alkyl; R2 is nitro or -N(R3)R4 where R3 is hydrogen or lower alkyl; R4 is hydroge...
WO/1993/025516A1	PALLADIUM CATALYZED ADDITION OF AMINES TO 3,4-EPOXY-1-BUTENE 4-amino-2-buten-1-ol is formed by the regioselective addition of primary amines to 3,4-epoxy-1-butene. A quantity of the primary amine is reacted with 3,4-epoxy-1-butene in a reaction medium in the presence of a catalyst. The reaction me...
WO/1993/025524A1	FUNGICIDAL INDOLE DERIVATIVES The invention relates to fungicidal compositions which comprise a carrier and, as active ingredient, an indole derivative of general formula (I), in which R represents a substituted phenyl group;R3 and R4 independently represent a hydrog...
WO/1993/025547A1	THE SULPHATE SALT OF A SUBSTITUTED TRIAZOLE, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE IN THERAPY The sulphate salt of N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]e thylamine is a selective agonist of 5-HT1-like receptors and is therefore useful in the treatment of clinical conditions, in particular migraine and associ...
WO/1993/024482A1	HETEROCYCLICALLY BISUBSTITUTED SULPHONYL AMINO(THIO)CARBONYL COMPOUNDS, The invention relates to novel heterocyclically bisubstituted sulphonyl amino(thio)carbonyl compounds of formula (I) in which Q is oxygen or sulphur, R?1¿ and R?2¿ are the same or different and mutually independently stand for a possib...
WO/1993/024481A1	7-SUBSTITUTED-6-FLUORO-1,4-DIHYDRO-4-OXO-QUINOLINE-3-CARBOXYLIC ACID COMPOUNDS AND RELATED COMPOUNDS AS ANTIBACTERIAL AGENTS Quinoline compounds of formula (I) wherein (A) R is hydrogen or C¿1?-C¿4? alkyl group; R¿1? is (i) a C¿3?-C¿6? cycloalkyl group which may be substituted with one or two halogen atoms, (ii) a phenyl group which may be substituted wit...
WO/1993/023402A1	3-AZETIDINYLTHIO-CARBAPENEME DERIVATIVES, THEIR PREPARATION AND USE AS ANTIMICROBIAL AGENTS A compound of formula (I) in which R1 is carboxy, COO- or protected carboxy, R2 is hydroxy(lower)alkyl or protected hydroxy(lower)alkyl, R3 is hydrogen or lower alkyl, and R4 is substituted lower alkyl or substituted lower alkenyl and R5...
WO/1993/021186A1	SUBSTITUTED 3-PYRROLIDINYLTHIO-CARBAPENEMS AS ANTIMICROBIAL AGENTS A compound of formula (I), in which R?1¿ is carboxy or protected carboxy, R?2¿ is 1-hydroxyethyl, R?3¿ is methyl, R?4¿ is optionally substituted pyridyl(lower)alkyl, optionally N-substituted 2-oxopiperazin-1-yl-(lower)alkyl, optional...
WO/1993/020065A1	NOVEL IMIDAZOLE DERIVATIVE, PHARMACEUTICAL USE THEREOF, AND INTERMEDIATE THEREFOR An imidazole derivative represented by general formula (I), wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof. A process for producing the derivative or salt, and a pharmaceutical use t...
WO/1993/020053A1	PYRIDYLSERINE DERIVATIVE A pyridylserine derivative represented by general formula (I) or a pharmaceutically acceptable salt thereof, wherein R1 represents hydrogen or an amino-protecting group, R2 represents hydrogen or a carboxyl-protecting group, A represents...
WO/1993/018743A1	AGENT FOR REGULATING THE GREASINESS OF THE SKIN The use of a compound having formula ((cis)-(I)), wherein R represents methyl or ethyl, for regulating the greasiness of the skin, particular novel physical forms of said compound, cosmetic compositions comprising said agent, processes f...
WO/1993/019061A1	ITRACONAZOLE AND SAPERCONAZOLE STEREOISOMERS The present invention is concerned with the stereoisomeric forms of itraconazole (X=Cl) and saperconazole (X=F), which may be represented by formula (cis-(I)), and the pharmaceutically acceptable acid addition salt forms thereof, process...
WO/1993/018029A1	IMIDAZOLE, TRIAZOLE AND TETRAZOLE DERIVATIVES A class of substituted imidazole, triazole and tetrazole derivatives of formula (I), wherein the broken circle represents two non-adjacent double bonds in any position in the five-membered ring; two, three or four of V,W,X,Y and Z repres...
WO/1993/016998A1	HERBICIDE N-[(PYRIMIDIN-2-YL)AMINOCARBONYL] BENZENE SULPHONAMIDES Herbicide N-[(pyrimidin-2-yl)aminocarbonyl] benzene sulphonamides of general formula I, wherein the substituents represent the following: R?1¿ represents methyl or ethyl; R?2¿ represents hydrogen or methyl; R?3¿ represents optionally ...
WO/1993/016986A1	AZO OXIME ETHERS AND THEIR USE AS FUNGICIDES Azo oxime ethers of general formula (I), in which X is CH or N, R1 is hydrogen, C1-C3alkyl, trifluoromethyl or cylclopropyl and R2 is aryl or heteroaryl, have an activity against phytopathogenic fungi. They can be used in the form of for...
WO/1993/017016A1	SULFONYLUREAS AS HERBICIDES The invention relates to compounds of formula (I) in which E is -CH= or -N=, and with the proviso that a) at least one of the radicals R3, R4, R5, R6 and R7 is C1-C4 alkyl, b) E is -CH= when X is halogen and c) E is -CH= when X or Y are ...
WO/1993/017015A1	SULFONYLUREAS AS HERBICIDES Compounds of formula (I) in which Q is a radical of formula (A) or (B) and in which R, X and Y are as defined in claim (1) have good pre- and postemergence-selective herbicidal and growth-regulating properties.
WO/1993/016985A1	CYANO-OXIME ETHERS, PROCESS FOR PRODUCING THEM, AGENTS CONTAINING THEM AND THEIR USE Cyano-oxime ethers of formula (I): R?1¿R?2¿CH-ON=C(CN)-R?3¿ in which R?1¿ is hydrogen or C¿1?-C¿4? alkyl, R?2¿ is a possibly substituted mono to tri-nuclear aliphatic or aromatic ring system which, besides carbon atoms, may contai...
WO/1993/017009A1	s-TRIAZINE DERIVATIVE AND REMEDY FOR ESTROGEN-DEPENDENT DISEASES CONTAINING THE SAME AS ACTIVE INGREDIENT An s-triazine derivative represented by general formula (I), or a pharmaceutically acceptable acid addition salt thereof, and a remedy for estrogen-dependent diseases containing the derivative as the active ingredient, wherein: (1) R1 an...
WO/1993/016052A1	NOVEL AZOLE DERIVATIVE, PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITION A novel azole derivative represented by general formula (I), a process for producing the same, and a pharmaceutical composition containing the same as the active ingredient, wherein R1 and R2 represent each independently hydrogen or C1-C...
WO/1993/015049A1	N-PHENYLINDOLE AND N-PYRIDYLINDOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES This invention relates to substituted N-arylindoles, a process for producing them and their use as herbicides. In particular, this invention relates to substituted N-arylindoles of formula (I) in which R is hydrogen; halogen; nitro; cyan...
WO/1993/015136A1	SEMICARBAZIDE/URETHANE STABILIZER Mixtures comprising semicarbazide/urethane reaction products of 4-amino-1,2,4-triazole, an aliphatic polyisocyanate and a reduced sugar or glycerol are particularly suited for protecting films, fibers, spandex and other polyurethane arti...
WO/1993/015041A1	ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES This invention relates to new ethanolamine derivatives having gut selective sympathomimetic and anti-pollakiuria activities and represented by general formula (I) wherein R?1¿ is aryl or a heterocyclic group, each of which may be substi...
WO/1993/014069A1	HETEROCYCLIC SULFONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF AND ANGIOTENSIN II Compounds of formula (I), wherein: A represents: a) a -VR6 group wherein v is -C(=O)-, -C(=O)O-, -CH2O-, -CH2OC(=O)-, -C(=S)-, -CH2OC(=O)NH-, -C(=S)O-, -CH2S-, -C(=O)NHSO2-, -SO2NHC(=O)- or -CH2OSiPh2-; b) a -CH2NR9R10 group or a -CONR9R...
WO/1993/013091A1	NOVEL QUINOLONE DERIVATIVE OR SALT THEREOF AND ANTIBACTERIAL CONTAINING THE SAME A quinolone derivative represented by general formula (1) or a salt thereof, and an antibacterial containing the same as the active ingredient, wherein R1 represents hydrogen or a protective group; R2 represents hydrogen, halogen or lowe...
WO/1993/013056A1	STABLE SALTS OF (+)-(1S,2R)-2-[[N-(2-HYDROXYLAMINO-2-OXOETHYL)-N-METHYL-AMINO]CARBONYL]CYCLOHEXA NE-1-CARBOXYLIC ACID, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM The novel salts of (+)-(1S,2R)-2-[[N-(2-hydroxylamino-2-oxoethyl)-N-methyl-amin o]carbonyl]cyclohexane-1-carboxylic acid with metals and organic bases, represented by general formula (I) wherein R and R' if taken together represent a biv...
WO/1993/013078A1	PYRIMIDINE OR TRIAZINE DERIVATIVE AND HERBICIDE A pyrimidine or triazine derivative represented by general formula (I) and a herbicide containing a salt thereof as the active ingredient, having an excellent herbicidal effect against harmful weeds growing in lowland and upland fields a...
WO/1993/013075A1	1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS This invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof in which R1, R2 and R3 independently represent hydrogen, halo, alkyl, alkoxy, phenoxy, phenyl, alkoxycarbonyl, -NR13R14, halogenated alkoxy,...
WO/1993/012095A1	QUINAZOLINONE ANTIANGINAL AGENTS Compounds of formula (I) and pharmaceutically acceptable salts thereof wherein R1 is H, C1-C4 alkyl, C1-C4 alkoxy or CONR5R6; R2 is H or C1-C4 alkyl; R3 is C2-C4 alkyl; R4 is H, C2-C4 alkanoyl optionally substituted with NR7R8, (hydroxy)...

Matches 1,251 - 1,300 out of 5,408	< 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 >