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WO/2021/228971A1 |
This invention provides a method of cleaving at least one covalent bond in at least one molecule, wherein said method comprises (a) colliding at least one magnetic body with said at least one molecule; and/or (b) triggering collision of ...
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WO/2021/231321A1 |
Provided herein are devices and methods of processing a sample that includes, in several embodiments, rotating one or more microfluidic chips that are mounted on a support plate. Each microfluidic chip can be rotated 180° on the support...
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WO/2021/219119A1 |
Provided are an immune cell treated by means of a magnetic field and the use thereof. A medium static magnetic field with an intensity of 0.3T can promote the secretion of granzymes and cytokines of mouse CD8+ T cells, increase the level...
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WO/2021/215179A1 |
The present invention acquires spectral data indicating the intensity, at each wavenumber or wavelength, of electromagnetic waves that have been directed at and affected by a cell suspension containing cells and a culture solution. The s...
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WO/2021/212653A1 |
Provided is a method for screening a treatment target for an acute radiation gastrointestinal syndrome, specifically comprising: overexpressing a transgenic mice model using a CreERT-loxP condition, and after irradiating by a large dose ...
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WO/2021/206686A1 |
A cell transfection apparatus may include a microfluidic chip. The microfluidic chip may include a fluid input port, a cell sorter to sort target cells from non-target cells in fluid received through the input port, a cell transfection r...
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WO/2021/187898A1 |
The present invention relates to a fibrocartilage preparation method and fibrocartilage prepared by the method.
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WO/2021/178566A1 |
Described are systems and methods for particle sorting. An array may comprise a substrate with a first surface and a second surface opposite to the first surface. The substrate may comprise a plurality of pores defining lumens extending ...
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WO/2021/173468A1 |
Methods for producing and utilizing primed platelets are provided, in which platelets are primed for release of specific granule types and/or active compounds by irradiation, for example with electromagnetic radiation, an electrical fiel...
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WO/2021/156366A1 |
The present invention relates to a device (1) for treating cells for stimulating cell growth, comprising a unit (2) for generating and emitting electric pulses and an electric field resulting therefrom, and a treatment space (3) that can...
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WO/2021/156373A1 |
The present invention is related to a treatment unit (3) having an inlet (3a) and an outlet (3b), and a treatment space (4) being formed inside the treatment unit (3) such that it can be penetrated by electric pulses, said treatment spac...
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WO/2021/156372A1 |
The present invention is related to a device (1), comprising a unit (2) for generating and emitting electric pulses, two or more electrodes or plates (2a, 2b) of a capacitor that are arranged in one electric circuit with said unit (2), a...
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WO/2021/156694A1 |
The object of the invention is a system for transferring quantum states information, particularly of macromolecular systems, comprising a source medium (2) of quantum information, a transmitter and receiver of quantum states information ...
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WO/2021/147671A1 |
The present invention relates to the technical field of cancer cell inhibition, and provides an ultrasonic treatment system and a dose control method. The system comprises: a control device; a first ultrasonic irradiation device, configu...
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WO/2021/139596A1 |
Provided are a gene expression switch/system (REDMAP system) based on red light and far-red light regulation for mammalian cells, comprising a photoreceptor and an effector. The REDMAP system has the capabilities of simple design, small ...
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WO/2021/127374A1 |
A test strip with selective white blood cell (WBC) lysis for release of WBC contents and the capture and holding of red blood cells (RBC), allowing for fast clearance and result interpretation and more accurate results at early time poin...
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WO/2021/114164A1 |
Provided is a method for preparing an exosome, which falls within the field of biotechnology. The method comprises the following steps: placing human astrocytes in a medium for culturing; performing circulatory stimulation on the human a...
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WO/2021/114160A1 |
A method for producing microvesicles, relating to the technical field of biological medicines, comprising the following steps: ultrasonically treating cells; culturing the ultrasonically treated cells in an incubator for 24-72 hours, and...
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WO/2021/109132A1 |
The present invention provides a composite material. The composite material comprises nanoparticles and a flexible substrate, the nanoparticles comprise one or more of carbon nanotubes, graphene, gold nanoparticles, and polydopamine nano...
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WO/2021/113330A1 |
An embodiment of a composition for target material separation includes: a body and one or more molecules coupled to the body and structured for functionalization of the composition. In embodiments, each of the one or more molecules can i...
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WO/2021/093331A1 |
An optical fiber surface electric field screening apparatus, comprising an extractor, the extractor being provided with an optical fiber, the optical fiber being prepared so as to form in the middle thereof a thinned part having a diamet...
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WO/2021/092689A1 |
A method of culturing a photosynthetic microorganism comprising culturing the photosynthetic microorganism under a first light spectrum for a first period of time and under a second light spectrum for a second period of time. Further des...
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WO/2021/086978A1 |
Microparticles and nanoparticles made of various materials that are used in various configurations are disclosed. The particles may be perfluorocarbon droplets with a lipid coating. The particles may be used in an acoustic cell selection...
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WO/2021/070617A1 |
Provided is an indirect extraction method, wherein a long-chain biopolymer is extracted from captured cells. This biopolymer extraction apparatus is characterized by comprising a cell capture part which has a film structure and in which ...
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WO/2021/071413A1 |
A yeast cell for use in the treatment and/or alleviation of allergy and/or symptoms caused by allergy, wherein the yeast cell has been treated with electromagnetic waves in the range of 1 GHz to 300 GHz, or said yeast cell has been grown...
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WO/2021/064244A1 |
There is provided a process for the separation of molecules from a suspension comprising cells at a concentration of at least 56 x 106 cells/ml, comprising the steps of: a) providing magnetic particles having a specific interaction with ...
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WO/2021/048550A1 |
The invention relates to a method for the transformation of host cells of a biofilm with heterologous nucleic acid, wherein the host cells are within the extracellular matrix of the biofilm, the method comprising: adding the heterologous...
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WO/2021/032179A1 |
Provided is an application of a Pseudomonas aeruginosa vaccine in preventing and treating bacterial infections associated with a burn or scald injury. The burn or scald injury comprises a burn or a scald. The degrees of burn injury compr...
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WO/2021/035009A1 |
A method of analyzing a sample comprising one or more species of microorganisms can include generating first droplets such that each of one or more microorganisms of a first portion of the sample is encapsulated within one of the first d...
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WO/2021/034990A1 |
A method and system of sensitization of cancerous cells such as melanoma cells by a nano-pulsed magnetic field is disclosed. The system includes a magnetic field generator to generate a nano-pulsed magnetic field directed at the area hav...
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WO/2021/030292A1 |
A method for making an acellular human amnion-derived composition configured for therapeutic use is disclosed and generally includes the steps: obtaining amniotic membrane tissue; testing the amniotic membrane tissue for pathogens; washi...
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WO/2021/025388A1 |
The present invention pertains to: an exosome derived from irradiated cancer cells; a pharmaceutical composition containing mature dendritic cells obtained using same; and a method for producing same. Provided are: a method for producing...
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WO/2021/021829A1 |
Systems, devices, and methods for producing a tissue specimen and performing subsequent biomechanical testing thereof to quantify various biological/physiological properties and characteristics. The system may include a bioreactor device...
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WO/2021/020694A1 |
The present invention relates to an electric fusion needle for producing somatic cell nuclear transfer embryos using an easily replaceable platinum wire, the electric fusion needle being characterized in that a ball of a replacement part...
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WO/2021/007170A1 |
Provided herein are improvements in cell culture methods and compositions related thereto. In partial particular, provided herein are compositions and methods, and kits increasing the cellular division times and viability. Also provided ...
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WO/2021/003451A1 |
Devices, systems, and kits for cell transfection are provided. A device includes a first electrode, a second electrode, and an electroporation zone therebetween where an electrical potential difference applied to the first and second ele...
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WO/2020/257866A1 |
A method for transforming a cell with a nucleic acid molecule, comprising applying a voltage to a solution comprising (i) the cell; (ii) the nucleic acid molecule; (iii) a leading electrolyte; and (iv) a terminating electrolyte; wherein ...
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WO/2020/263533A1 |
A method of identifying a lead or candidate compound that modulates the activity of GTPase-Activating Protein SH3 Domain-Binding Proteins (G3BP) is provided, which includes determining whether a compound modulates the interaction between...
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WO/2020/256520A1 |
The present invention relates to a method for producing exosomes by electrical stimulation and, more specifically, to a method for producing exosomes, comprising the steps of: (a) applying radio wave electrical stimulation to cells and c...
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WO/2020/249616A1 |
A method of upregulating the synthesis of pyruvate and/or a metabolite of pyruvate in a photosynthetic microorganism, a method for the photosynthetic production of a one, two, three or four carbon compounds, and a method for the producti...
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WO/2020/232437A1 |
Disclosed are a system, device, and method for the electroporation of cells. Systems, devices and methods for electroporation of living cells and the introduction of selected molecules into the cells utilizes a fluidic system where livin...
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WO/2020/210023A1 |
CAR T cell therapies have shown promise in treating human blood cell cancer. The preparation of CAR T cells involves many complex, time consuming steps prior to infusion of the CAR T cells into a cancer patient. One step in the process t...
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WO/2020/210458A1 |
Methods of using pulsed focused ultrasound (pFUS) therapy to treat pancreatic disorders such as type 1 diabetes, pancreatitis, and pancreatic cancer are provided. The methods utilize pulsed focused ultrasound (pFUS) therapy either by its...
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WO/2020/205862A1 |
An apparatus includes multiple first reservoirs and multiple second reservoirs joined with a substrate. Selected ones of the multiple first reservoirs include a reducing agent, and first reservoir surfaces of selected ones of the multipl...
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WO/2020/185622A1 |
Described is a low voltage, pulsed electrical stimulation device for upregulating expression of klotho, a useful protein, by tissues. Also described are methods of enhancing expression of klotho in cells.
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WO/2020/183984A1 |
The present invention addresses the problem of providing a method for introducing a substance into a protoplast or an alga by electroporation under novel voltage applying conditions. The problem can be solved by a method for introducin...
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WO/2020/177456A1 |
Mutagenesis is carried out on hyaluronidase-producing Lactobacillus plantarum to obtain a high hyaluronidase-producing mutant strain of Lactobacillus plantarum CnT012-56, the accession number being: CGMCC NO.16836. Lactobacillus plantaru...
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WO/2020/171783A1 |
The present invention proposes a system (100) for subjecting a group of cells placed onto a surface (s1) of a vessel (4) when such vessel (4) is introduced into the system (100) and then the system (100) is run, to magnetofection using a...
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WO/2020/161942A1 |
This growth promotion method promotes the growth of an organism. An organism disposed in a growth environment has imparted thereto a 0.5-1000MHz high frequency AC electrical field having a frequency band such that water dielectric loss b...
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WO/2020/160501A1 |
Systems and methods described herein employ focused acoustic energy applied to a reservoir containing a fluid to eject a fluid sample from the fluid sample reservoir, e.g. to an inlet of an analytical device. In many embodiments, the eje...
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