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WO/2021/060701A1 |
The present application relates to a variant polypeptide with reduced meso-diaminopimelate dehydrogenase activity and a method for producing L-threonine using same.
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WO/2021/060438A1 |
The present invention provides a method for producing L-amino acids by fermentation using a bacterium belonging to the order Enterobacterales which has been modified to attenuate expression of a gene encoding a protein having indolepyruv...
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WO/2021/060696A1 |
The present application relates to a modified polypeptide with attenuated dihydrodipicolinate reductase activity, and a method for producing L-threonine by using same.
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WO/2021/058691A1 |
The invention is directed to methods to produce β-alanine or salts thereof from acrylic acid using a recombinant aspartase-like protein as catalyst.
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WO/2021/052989A1 |
The present disclosure relates to methods for production of 4-hydroxytryptamine and derivatives thereof in a yeast cell. Herein are also disclosed methods for production of halogenated tryptophans and derivatives thereof in a cell. Herei...
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WO/2021/048353A1 |
The present invention provides a recombinant bacterium of the genus Corynebacterium comprising a L-threonine exporter gene rhtC from E. coli and wherein in said bacterium the native L-threonine transporter gene thrE is deleted and a meth...
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WO/2021/049852A1 |
The present invention relates to a composition that is effective in improving skin wrinkles and inflammation, comprising, as an active ingredient, a cell extract of a Lactobacillus paracasei subsp. tolerans SW1 strain newly isolated from...
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WO/2021/049866A1 |
The present application relates to an L-threonine export protein variant, a microorganism including same, and a method for production of L-threonine using same.
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WO/2021/042460A1 |
A transport protein coding gene, and a method for using a strain containing said gene to increase L-tryptophan production. Specifically, strain L-tryptophan production efficiency can be improved by means of heterologous expression of the...
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WO/2021/043451A1 |
The invention provides polynucleotides and nucleic acid molecules encoding piperine synthases and proteins and enzyme functional for converting piperoyl-CoA and piperidine to piperine. The invention also provides a method of producing an...
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WO/2021/045472A1 |
The present application relates to a novel promoter and a method for producing a desired substance using same.
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WO/2021/037166A1 |
Provided are an Escherichia coli strain K12-based recombinant strain or a derivative strain thereof after site-directed mutagenesis, a construction method therefor and use thereof. Said recombinant strain is subjected to site-directed mu...
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WO/2021/038095A1 |
The present invention relates to methods for the preparation of α-hydroxyacyl compounds, and peptides for the catalyzed formation of α-hydroxyacyl compounds as well as their use in the preparation of α-hydroxyacyl compounds.
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WO/2021/037165A1 |
Provided is a nucleotide sequence. The sequence is a sequence formed by mutation of a base at the 1049th site of a wild-type deoB gene coding sequence shown in SEQ ID NO: 1 or a promoter nucleotide sequence by mutation of a base at the -...
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WO/2021/041932A2 |
Provided herein, inter alia, are genetically engineered microbes and methods of use thereof for producing L-4-chlorokynrenine from L-Tryptophan. The genetically engineered microbes include, inter alia, one or more exogenous nucleic acids...
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WO/2021/035793A1 |
Provided is an MviN protein mutant, said mutant improving corynebacterium glutamic acid and lysine production capability by means of introducing an amino acid mutation at a set position in an MviN protein amino acid sequence.
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WO/2021/037190A1 |
Provided are a 2-isopropylmalate synthase, L-leucine-producing genetically engineered bacteria, and applications thereof, related to the field of metabolic engineering. The genetically engineered bacteria are acquired by overexpressing i...
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WO/2021/036901A1 |
An application of a branched-chain α-ketoacid dehydrogenase complex in preparation of malonyl coenzyme A. A method for preparing malonyl coenzyme A by using the branched-chain α-ketoacid dehydrogenase complex. The method comprises: int...
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WO/2021/032513A1 |
The present invention relates to a process, by means of which polyurethanes, which have been formed from polyether polyols and aromatic isocyanates, can be decomposed to polyether polyols and aromatic amines.
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WO/2021/030835A1 |
The present disclosure describes the engineering of microbial cells for fermentative production of 3-anino-4-hydroxybenzoic acid and provides novel engineered microbial cells and cultures, as well as related 3-amino-4-hydroxybenzoic acid...
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WO/2021/017317A1 |
A method for inhibiting the photodegradation of ergothioneine, and an application therefor, comprising the following steps: adding hyaluronate to a solution containing ergothioneine; the content of ergothioneine is 0.0005-0.01 wt%, and t...
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WO/2021/015242A1 |
[Problem] To provide a genetically modified microorganism and a method for producing a diamine compound. [Solution] This genetically modified microorganism expresses an enzyme involved in synthesis of a diamine compound, wherein the diam...
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WO/2021/010268A1 |
Provided is a method for producing an N-substituted amide compound/amide compound copolymer using a biocatalyst, the method comprising: (A) a step for reacting an amide compound with an amine in the presence of an enzyme that catalyzes a...
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WO/2021/007127A1 |
Disclosed herein are methods for the selective substitution of a hydrogen bonded to a carbon atom (e.g., a hydrogen of an aliphatic methylene group) of a compound, which comprise contacting the compound with a substituent in the presence...
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WO/2021/002195A1 |
The present invention addresses the problem of providing a practical means for producing cysteine from glutathione, said means being suited for use in the field of foodstuffs. The present invention produces cysteine from glutathione usin...
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WO/2020/262860A1 |
The present invention relates to a method for increasing the content of tryptophan in bean sprouts by using a plant elicitor, and extracting the tryptophan therefrom and, more particularly, to a method for building up tryptophan as a use...
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WO/2020/263722A1 |
The present strains and methods relate to yeast cells that over-overproduce selected endogenous proteins having a high amino acid content of a selected amino acid. The yeast can be used in a conventional bioethanol production facility to...
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WO/2020/263732A1 |
Described are compositions and methods relating to yeast having a genetic mutation that results in decreased amounts of Cdc42 effector proteins, resulting in increased alcohol and lysine production. Such yeast is well-suited for use comm...
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WO/2020/263041A1 |
The present application relates to a method for producing a sulfur-containing amino acid or a sulfur-containing amino acid derivative.
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WO/2020/263043A1 |
The present application relates to a method for producing a sulfur-bearing amino acid or a sulfur-bearing amino acid derivative.
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WO/2020/254699A1 |
The present invention relates to a method for municipal solid waste (MSW) reclamation in a continuous or discontinuous process, first for converting said waste into organic biomass and subsequently extracting and recovering as many of th...
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WO/2020/256415A1 |
The present invention relates to microorganisms for producing L-tyrosine, including a gene for encoding a trp operon regulatory region and a prephenate dehydratase operably linked thereto, and a method for producing L-tyrosine by using t...
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WO/2020/249616A1 |
A method of upregulating the synthesis of pyruvate and/or a metabolite of pyruvate in a photosynthetic microorganism, a method for the photosynthetic production of a one, two, three or four carbon compounds, and a method for the producti...
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WO/2020/244380A1 |
Provided is a means of knocking out the glnR gene by means of homologous recombination, and a method and application thereof for obtaining a Lactobacillus brevis glnR knockout strain to improve the ability of Lactobacillus brevis γ-amin...
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WO/2020/237701A1 |
Provided are a high-yield L-histidine genetically engineered bacterium strain, and a construction method therefor and an application thereof, integrating a corynebacterium glutamicum ATP phosphoribosyl transferase HisG mutant encoding ge...
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WO/2020/237552A1 |
Provided are a transaminase mutant and a method for producing chiral amines using the transaminase mutant. The amino acid sequence of the transaminase mutant is an amino acid sequence obtained after mutation occurs to the amino acid sequ...
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WO/2020/232519A1 |
The present invention describes the composition of an animal feed additive containing a nutrient-rich fermented broth obtained by means of a fermentation process using a genetically modified microorganism. The non-pathogenic bacterium Co...
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WO/2020/233451A1 |
Disclosed in the present invention is an L-glutamate dehydrogenase mutant, the sequence of the L-glutamate dehydrogenase mutant being a sequence in which amino acid residue A at position 175 in SEQ ID NO. 1 is mutated to be G, and amino ...
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WO/2020/230044A1 |
The present invention relates to a process for preparing an extract with antimicrobial activity from by-products or waste products of the fruit and vegetable industry. The process comprises a step of mixing the by-products or waste produ...
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WO/2020/231426A1 |
Modified host cell and cyanobacterial cells that are capable of producing various mycosporine-like amino acids (MAAs), useful as natural UV absorbing compound, are described.
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WO/2020/232063A1 |
Disclosed herein are synergistic compositions and methods using arginine -producing bacteria and/or ammonia-consuming bacteria in combination with a checkpoint inhibitor for use in treating cancer.
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WO/2020/226341A1 |
The present application relates to a microorganism producing L-amino acid or a precursor thereof and a method for producing L-amino acid or a precursor thereof by using the microorganism.
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WO/2020/218736A1 |
The present application relates to a microorganism with enhanced L-histidine production capacity and a method for producing histidine by using same.
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WO/2020/219859A1 |
Disclosed are trans-enoyl CoA reductase (TER) enzymes and nucleic acids encoding them. In some cases, the TER enzymes are non- natural, engineered trans-enoyl CoA reductase. TER enzymes were shown to catalyse the conversion of 5-carboxy-...
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WO/2020/219866A1 |
Disclosed are transaminase (TA) enzymes and nucleic acids encoding them. In some cases, the transaminase enzymes are non-natural, engineered transaminases. Also disclosed are biosynthetic methods and engineered microorganisms that enhanc...
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WO/2020/218624A1 |
The present invention addresses the problem of providing a method for more easily and highly efficiently industrially producing high-purity L-cyclic amino acids from cyclic amino acids that have a double bond at the 1 position. According...
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WO/2020/218737A1 |
The present application relates to a microorganism with enhanced L-threonine production capacity, and a production method using same.
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WO/2020/219863A1 |
Disclosed are biosynthetic methods and engineered microorganism that enhance or improve the biosynthesis of hexamethylenediamine, caproic acid or caprolactam. The engineered microorganisms include selected aldehyde dehydrogenase activity.
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WO/2020/213132A1 |
A method for producing a plasmalogen-containing functional material, said method comprising an enzymatic treatment step for treating an animal tissue containing plasmalogen with a protease, and an extraction step for extracting the prote...
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WO/2020/214940A1 |
Described herein are enzymes, such as for example, methanol dehydrogenase (MDH), 3-hexulose-6-phosphate isomerase (PHI), 3-hexulose-6-phosphate synthase (HPS), ribose-5-phosphate isomerase (RPI), ribulose 5-phosphate 3-epimerase (RPE), t...
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