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WO/2023/128568A1 |
The present application relates to: a microorganism in which erythronate-4-phosphate dehydrogenase protein activity is weakened; a method for producing O-phosphoserine, cysteine, and a cysteine derivative by using same; an O-phosphoserin...
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WO/2023/127752A1 |
A polypeptide that has a sequence having a sequence identity of 90% or more with respect to a sequence obtained by modifying one amino acid residue in the amino acid sequence represented by SEQ ID NO: 1, and that has a catalytic activity...
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WO/2023/121423A1 |
The present application relates to a method for preparing amino acid granules from a fermented solution, wherein the prepared amino acid granules are free of fungus.
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WO/2023/121055A1 |
The present invention relates to a microorganism capable of producing L-isoleucine, into which a gene encoding an exogenous glutamate dehydrogenate is introduced, an L-isoleucine producing method using the microorganism, and an L-isoleuc...
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WO/2023/117756A1 |
The present invention relates to a process for recovering aminobenzoic acid from an aqueous mother liquor which is produced on crystallization of aminobenzoic acid. The process comprises a step (A) of fermenting a suitable fermentable ra...
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WO/2023/111055A1 |
The present invention relates to the use of special variants of the 3-desoxyarabinoheptulosanate-7-phosphate synthase for preparing ortho-aminobenzoic acid by microbial fermentation and microorganisms which are suitable for this purpose.
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WO/2023/111053A2 |
The present invention relates to the preparation of ortho-aminobenzoic acid by means of microbial fermentation, wherein mixtures of glucose and xylose are used as fermentable substrates.
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WO/2023/106300A1 |
The present disclosure provides a system for culturing animal cells by using, as a source of nutrient, components derived from a living organism such as algae, and for reutilizing a waste culture liquid obtained therefrom. The present ...
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WO/2023/104957A1 |
The invention relates to a method for sequestering carbon or removing carbon dioxide from air using a bioreactor inoculated with autotrophic microorganisms, the carbon dioxide from air being the sole carbon source.
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WO/2023/106543A1 |
The present invention relates to a Corynebacterium glutamicum variant having improved L-lysine production ability and a method for producing L-lysine by using same. The Corynebacterium glutamicum variant can have an improved L-lysine pro...
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WO/2023/102816A1 |
Provided are a fusion gene comprising a PhoD signal peptide and a rocF gene, an expression cassette comprising the fusion gene, and a recombinant expression vector. Also provided are a genetically engineered bacterium and a construction ...
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WO/2023/106620A1 |
The present invention relates to a method for producing tyrosine with high purity from a fermented broth containing tyrosine produced by microbial fermentation, the method comprising the steps of: adding a basic solution and dissolving t...
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WO/2023/102374A1 |
The present invention relates to an aminotransaminase useful in the synthesis of (R)-3-aminobutan-1-ol (RABO). The present invention also provides a process of preparing (R)-3-aminobutan-1-ol (RABO) with the disclosed aminotransaminase.
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WO/2023/098453A1 |
Provided are a nitrile hydratase mutant or a fragment thereof and the use thereof. Compared with wild-type nitrile hydratase, the nitrile hydratase mutant or fragment thereof comprises the following mutations: mutation I, which is a hydr...
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WO/2023/095896A1 |
This genetically modified microorganism satisfies at least one condition selected from the group consisting of conditions (I) and (II). Condition (I): in comparison with a wild-type microorganism corresponding to the genetically modified...
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WO/2023/094011A1 |
The invention relates to a method for preparing L-cysteic acid, in which method O-acetyl-L-serine (OAS) is reacted with at least one enzyme selected from the class of O-acetyl-L-serine-sulfhydrylases (OAS sulfhydrylases, EC 4.2.99.8) in ...
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WO/2023/094010A1 |
The invention relates to a process for producing taurine from O-acetyl-L-serine (OAS) by way of biotransformation. In a first process step (biotransformation 1), L-cysteic acid is produced from O-acetyl-L-serine (OAS) using an enzyme sel...
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WO/2023/090378A1 |
Provided is a method for efficiently producing 3,4-dihydroxyphenylalanine from protocatechuic acid using cultured cells of a microorganism. According to the present invention, a production method for 3,4-dihydroxyphenylalanine includes...
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WO/2023/089028A1 |
The present invention relates to a microorganism genetically modified for improved production of valine, wherein the microorganism overexpresses a ilvA gene coding a threonine deaminase and/or exhibits an increased threonine deaminase ac...
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WO/2023/090821A1 |
The present application relates to a novel Aspergillus oryzae CJI1100 strain and a mycelium produced therefrom. Using the novel Aspergillus oryzae CJI1100 strain of the present application, a mycelium including all the kinds of essential...
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WO/2023/088077A1 |
Provided is an engineered polypeptide capable of catalyzing the asymmetric hydrolysis of 3-isobutylglutarimide to generate (R) - (-) -3- (carbamoylmethyl) -5-methylhexanoic acid. The engineered polypeptide has high stereoselectivity, hig...
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WO/2023/086520A2 |
The present disclosure provides engineered enzymes and methods for preparing tyrosine and tyrosine analogs from a donor amino acid and phenols in a single step. Also disclosed are methods to engineer enzymes having such 'tyrosine synthas...
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WO/2023/079812A1 |
This method for producing an ultrafine-bubble-containing liquid includes a supply step for supplying a liquid L10 that contains at least one substance selected from the group indicated below to a liquid supply region 22 in which is dispo...
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WO/2023/075397A1 |
The present application provides a LysE variant.
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WO/2023/071580A1 |
Provided are a recombinant microorganism constructed based on a lysine efflux protein, a method for constructing the recombinant microorganism, a lysine producing strain, and a method for producing lysine. The polypeptide having the sequ...
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WO/2023/068295A1 |
The present invention relates to a novel bioprocess and bioprocess device in which the CO2 in a gas can be utilized as a substrate. The bioprocess involves (a) causing a CO2-containing gas (G) to contact an alkali, thereby causing the al...
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WO/2023/063547A1 |
The present invention relates to a Corynebacterium glutamicum variant having improved L-lysine production ability and a method for producing L-lysine by using same. The Corynebacterium glutamicum variant is increased or strengthened in t...
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WO/2023/063763A1 |
The present application pertains to: an L-arginine-producing microorganism in which proteins containing the amino acid sequence of SEQ ID NO: 1 are attenuated; and a method for producing L-arginine using same.
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WO/2023/056699A1 |
Disclosed are a genetically engineered strain capable of producing L-alanine, a construction method therefor, and an application thereof. A genetically engineered strain capable of efficiently producing alanine at a high temperature of 4...
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WO/2023/056700A1 |
A genetically engineered bacterial strain producing DL-alanine, a construction method therefor and an application thereof, which relate to the field of bioengineering. By enhancing a glycolytic pathway and introducing a thermostable alan...
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WO/2023/054882A1 |
The present application relates to a novel acetohydroxy acid synthase (AHAS) mutant with enhanced L-isoleucine productivity, a microorganism including same, and a method for producing L-isoleucine, using the microorganism and aims to fin...
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WO/2023/050516A1 |
Provided are a transaminase mutant and an application thereof. The transaminase mutant has an amino acid mutation based on a sequence shown in SEQ ID NO: 1, the amino acid mutation being a single position mutation from among W60Y, Y168A,...
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WO/2023/054881A1 |
The present application relates to a novel acetohydroxy acid synthase (AHAS) variant that improves L-isoleucine production ability, a microorganism containing same, and a method for producing L-isoleucine using the microorganism. The pur...
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WO/2023/048480A1 |
The present application relates to a strain and a microorganism for producing high concentration L-glutamic acid and a method of use thereof.
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WO/2023/042081A1 |
The invention relates to a process to produce a (1r,4r)-4-substituted cyclohexane-1-amine [further referred as trans-4-substituted cyclohexane-1-amine] of formula (T), starting from a diastereomeric mixture of 4-substituted cyclohexane-1...
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WO/2023/041425A1 |
The present invention concerns C. glutamicum strains expressing modified gluconate repressor proteins GntR1 and GntR2 and a method for the fermentative production of L-lysine using such C. glutamicum strains.
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WO/2023/044393A1 |
Improved production of threonine from E. coli by fermentation is accomplished by attenuation of the expression of either or both of the yafV gene encoding omega-amidase (a.k.a. 2-oxoglutaramate amidase). The strain also has attenuated ex...
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WO/2023/041515A2 |
The invention provides a method for preparing an aqueous (meth)acrylamide solution, said method comprising the following steps: (a) adding the following components (i) to (iii) to a reactor to obtain a composition for bioconversion: (i) ...
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WO/2023/041768A1 |
The invention relates to a method for the processing and transport of hexane-1,6-diamine or pentane-1,5-diamine comprising the steps of: a) Providing a first composition including 60 to 98 wt.-% water and 2 to 40 wt.-% hexane-1,6-diamine...
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WO/2023/038250A1 |
The present invention relates to a recombinant microorganism with the controlled ability to produce polyols or exopolymers. The present invention also relates to a selective production or simultaneous production method for polyols or exo...
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WO/2023/029310A1 |
Provided is a synthesis method for L-glufosinate-ammonium, in the technical field of pesticide production. The synthesis method for L-glufosinate-ammonium comprises: using a hydantoin derivative as a raw material and water as a solvent, ...
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WO/2023/032371A1 |
The present invention addresses the problem of providing a novel method for producing a γ-aminobutyric acid (GABA) powder and a product that contains a GABA powder produced by the production method. The present invention provides a meth...
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WO/2023/031333A1 |
The present invention relates to a process for the synthesis of an organic molecule, comprising the use of a polymeric soluble support. The invention further relates to the polymeric soluble support, and to a process for the synthesis th...
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WO/2023/027284A1 |
The present application relates to: a novel acetohydroxy acid synthase subunit (ilvN) variant; a polynucleotide encoding the variant; an expression vector comprising the polynucleotide; microorganisms producing L-valine including the ace...
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WO/2023/027348A1 |
The present application relates to: a novel regulator of acetate metabolism A-variant; a polynucleotide encoding the variant; a microorganism for producing an L-branched chain amino acid that comprises the variant or the polynucleotide; ...
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WO/2023/025656A1 |
The present invention relates to a modified dehydrogenase, wherein one or more amino acid residues of the dehydrogenase are modified as compared to an unmodified dehydrogenase, and wherein the modified dehydrogenase has an increased rati...
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WO/2023/023201A1 |
The present invention relates to precious metal (Pd/Pt/Rh/Ru) free, preferably Pd free, processes for preparing a compound having formula (1) wherein: R1, R2, and X are as defined in the specification, or a salt thereof. Preferably, the ...
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WO/2023/012819A1 |
The present invention provides recombinant transaminase polypeptides, fusion protein comprising the same and process of designing the same. Further, the present invention provides a process of preparing chiral amines catalyzed by the rec...
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WO/2023/011627A1 |
Disclosed are a carbonyl reductase mutant and application thereof. Mutation sites of the carbonyl reductase mutant of the present invention comprise the 88th, 142nd, 190th, and 193rd positions of the amino acid sequence shown in SEQ ID N...
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WO/2023/008862A1 |
The application relates to a microorganism having weakened activity of a LacI family DNA-binding transcriptional regulator protein, and an L-glutamic acid production method using same. A Corynebacterium sp. microorganism having weakened ...
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