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WO/2022/220263A1 |
An ergothioneine production method comprising: (a) a step for culturing an alga belonging to Cyanidiophyceae; (b) a step for collecting the alga belonging to Cyanidiophyceae from the culture liquid after the culture; and (c) a step for e...
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WO/2022/220329A1 |
The present application relates to a major facilitator superfamily permease variant, a corynebacterium glutamicum strain comprising the variant, and a method for producing L-lysine using the strain.
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WO/2022/220326A1 |
The present application relates to a sugar phosphate isomerase/epimerase variant, a corynebacterium glutamicum strain comprising the variant, and a method for producing L-lysine using the strain.
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WO/2022/215799A1 |
The present application relates to a novel 2-isopropylmalate synthase variant, a corynebacterium glutamicum strain comprising the variant, and a method for producing L-valine using the strain.
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WO/2022/217117A1 |
The present invention relates to methods of producing compounds of interest in a recombinant microorganism. In particular, the present invention relates to using a recombinant microorganism comprising a heterologous nucleic acid encoding...
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WO/2022/215796A1 |
The present application relates to a novel transcriptional regulator variant, a corynebacterium glutamicum strain comprising the variant, and a method for producing L-valine using the strain.
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WO/2022/215798A1 |
The present application relates to a novel dihydrolipoamide acetyltransferase variant, a corynebacterium glutamicum strain comprising the variant, and a method for producing L-valine using the strain.
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WO/2022/215801A1 |
The present application relates to a novel glyceraldehyde-3-phosphate dehydrogenase variant, a corynebacterium glutamicum strain comprising the variant, and a method for producing L-valine using the strain.
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WO/2022/215800A1 |
The present application relates to a novel branched-chain amino acid permease variant, a corynebacterium glutamicum strain comprising the variant, and a method for producing L-valine using the strain.
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WO/2022/215802A1 |
The present application relates to a novel sugar porter-family MFS transporter variant, a corynebacterium glutamicum strain comprising the variant, and a method for producing L-valine using the strain.
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WO/2022/216088A1 |
The present application relates to: an L-arginine-producing microorganism in which a protein containing an amino acid sequence of SEQ ID NO: 1 is attenuated; and an L-arginine production method using the microorganism.
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WO/2022/215797A1 |
The present application relates to a novel WhiB-affiliated transcriptional regulator WhcA variant, a corynebacterium glutamicum strain comprising the variant, and a method for producing L-valine using the strain.
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WO/2022/210708A1 |
[Problem] To provide a recombinant microorganism having 2,3-dehydroadipyl-CoA reductase activity and a method for producing a C6 compound. Also, to provide a recombinant microorganism capable of producing adipic acid or an adipic acid de...
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WO/2022/207753A1 |
Methods for the production of L-glufosinate (also known as phosphinothricin or (S)-2- amino-4-(hydroxy(methyl)phosphonoyl)butanoic acid) ammonium salt are provided. The methods comprise a refined multi-step process. The first step involv...
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WO/2022/210228A1 |
The present disclosure provides a novel IPMS mutant which can impart, to various microorganisms, the ability to produce a derivative including L-leucine or a precursor thereof. The IPMS mutant contains at least two amino acid substitutio...
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WO/2022/210685A1 |
The purpose of the present invention is to provide: a nitrifying bacteria formulation that is capable of allowing a sufficient nitrification reaction to proceed even in an environment having a high ionic concentration (salt concentration...
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WO/2022/207543A1 |
The present invention relates to an enzymatically catalyzed method for producing L-glufosinate or a phosphoester thereof. The method comprises a step in which an activated L-homoserine HA is reacted with a substrate S selected from methy...
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WO/2022/209763A1 |
[Problem] To provide a recombinant polypeptide having excellent carboxylic acid reducing activity and a method for producing an aliphatic compound using the recombinant polypeptide. [Solution] A recombinant polypeptide characterized by: ...
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WO/2022/199460A1 |
Disclosed are an aspartate kinase gene expression regulatory sequence and the use thereof. By modifying positions 366-373 of a sequence represented by SEQ ID NO: 1, a polynucleotide formed by linking the sequence with a start codon GTG o...
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WO/2022/198846A1 |
Provided are a microorganism for producing a pantoic acid, and a construction method therefor and an application thereof. The microorganism for producing the pantoic acid is obtained by knocking out a gene in Escherichia coli and introdu...
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WO/2022/199660A1 |
Disclosed are Lactobacillus rhamnosus having the accession number of CCTCC NO: M 2021185, a ferment lysate prepared thereby for regulating skin microecology, and a preparation method for the lysate ferment. The ferment lysate comprises t...
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WO/2022/202952A1 |
The present invention pertains to a modified (mutant) nicotinamide phosphoribosyltransferase and a method for producing nicotinamide mononucleotide using the same. The modified nicotinamide phosphoribosyltransferase (Nampt) according to ...
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WO/2022/195237A1 |
The invention relates to a hybrid molecule comprising at least one antibody Fc fragment covalently bound to at least one fibrin-derived peptide having at least one citrullyl residue, the uses of such a hybrid molecule, and the method for...
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WO/2022/195238A1 |
The invention relates to a hybrid molecule comprising a fibrin-derived citrullinated peptide and an antibody or antibody fragment which binds to CD38 and/or CD138, to the uses of such a hybrid molecule, and also to the method for produci...
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WO/2022/196919A1 |
The present invention relates to a Corynebacterium glutamicum variant having an improved L-citrulline production ability, and a method for producing L-citrulline by using same. The Corynebacterium glutamicum variant can hinder the genera...
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WO/2022/191467A1 |
The present application relates to a microorganism of genus Corynebacterium which produces L-amino acids, a method for producing L-amino acids using same, an L-amino acid production use, and a composition for producing L-amino acids.
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WO/2022/192153A1 |
Formaldehyde is obtained from CO2 through hydrogenation of CO2 to methanol while the subsequent oxidation of methanol yields formaldehyde. This formaldehyde combined with the electrochemically produced glycolaldehyde generates sugars, th...
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WO/2022/191358A1 |
The present invention relates to a Corynebacterium glutamicum variant having an improved L-lysine production ability, and a method for producing L-lysine by using same. The Corynebacterium glutamicum variant increases or enhances the exp...
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WO/2022/191635A1 |
The present application relates to a novel citrate synthase variant, a microorganism comprising the variant, and a method for producing L-amino acids using the microorganism.
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WO/2022/191630A1 |
The present application relates to a novel citrate synthase variant, a microorganism comprising the variant, and a method for producing L-valine by using the microorganism.
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WO/2022/191633A1 |
The present application relates to: a novel citrate synthase variant; a microorganism comprising the variant; and a method for producing O-acetyl-L-homoserine and L-methionine using the microorganism.
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WO/2022/191303A1 |
The present invention addresses the problem of providing a practical means for generating cysteine from protein, said means also being suited for use in the field of foodstuffs (foodstuff applications). According to the present invention...
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WO/2022/191357A1 |
The present invention relates to a Corynebacterium glutamicum variant having improved L-lysine production ability and a method for producing L-lysine using same, wherein the variant can increase or enhance the expression of a gene encodi...
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WO/2022/185872A1 |
With the present invention, ergothioneine or a related substance thereof is produced at a low cost in a large quantity through biosynthesis. The present invention pertains to: a production method that is for ergothioneine or a related su...
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WO/2022/185265A1 |
The invention provides a fermentation enhancing composition, which aids in the use or reuse of the spent wash. The spent wash is heated continuously to collect condensate water. The water is used for the dilution of molasses for yeast gr...
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WO/2022/185873A1 |
The present invention addresses the problem of producing a large quantity of ergothioneine at low cost. The present invention relates to: an ergothioneine production method including a step for culturing microorganisms in which the YbaO ...
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WO/2022/186487A1 |
The present application relates to a modified isopropylmalate synthase variant and a method for producing L-leucine by using same.
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WO/2022/174597A1 |
Provided are a genetically engineered bacterium for producing L-sarcosine, a construction method therefor and the use thereof. The genetically engineered bacterium takes escherichia coli as a host, and is obtained by means of integrating...
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WO/2022/172829A1 |
According to the method of the present invention (the first embodiment) that comprises step (A) for producing aminobenzaldehyde (2) by formylating dimethylaniline (1), optically active indazolylalanine (8) or indazolyl aldehyde (3) can b...
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WO/2022/172880A1 |
The present invention pertains to a method for producing an amide compound from a nitrile compound in the presence of a biocatalyst having nitrile hydratase activity. An amide compound is efficiently produced using this method by suppres...
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WO/2022/174177A1 |
The present disclosure relates to engineered microbial host cells comprising exogenous genes coding for proteins responsible for converting histidine and cysteine into ergothioneine in greater efficiency than the wild-type cells. Also pr...
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WO/2022/166838A1 |
Provided is a transaminase mutant, having a sequence on which an amino acid mutation takes place on the basis of the sequence as represented by SEQ ID NO: 13. Provided is an enatioselective flipped ω-transaminase ATA-117 mutant. The ami...
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WO/2022/166104A1 |
Provided is a method for synthesizing a chiral amine compound. An amino reaction is performed on a ketone substrate by means of a transaminase under the action of an amino donor, and the chiral amine compound is obtained. A conserved ami...
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WO/2022/167135A1 |
The present invention relates generally to the field of plant-based food. In particular, the present invention relates to improving the amino acid profile of plant-based food products. One embodiment of the present invention relates to t...
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WO/2022/166103A1 |
Provided are a transaminase mutant and an application thereof. The transaminase mutant is obtained by mutating one or more amino acids in SEQ ID NO: 2 or is a mutant obtained by taking the sequence SEQ ID NO: 1 of wild-type CVTA transami...
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WO/2022/168952A1 |
The present invention provides: an enzyme that transfers a prenyl group to an arginine residue or an arginine analog residue in a peptide, or to arginine or an arginine analog, wherein the enzyme includes an amino acid sequence represent...
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WO/2022/163920A1 |
The present application relates to a novel cysteine sulfinate desulfinase variant, Corynebacterium stationis strain comprising the variant, and a method for producing L-valine using the strain.
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WO/2022/163940A1 |
The present application relates to a novel galactoside O-acetyltransferase variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-glutamic acid using the strain.
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WO/2022/163923A1 |
The present application relates to a novel ATP phosphoribosyltransferase variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-valine using the strain.
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WO/2022/163912A1 |
The present application relates to a type II citrate synthase variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-lysine using the strain.
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