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WO/2020/022847A1 |
The present invention relates to a recombinant yeast strain having sterol productivity, a preparation method therefor and a use thereof and, more specifically, to: a recombinant yeast strain capable of producing cholesterol and cholester...
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WO/2019/182318A9 |
The invention relates to a method for preparing compound K by using ginseng sprouts, and an antioxidative and antibacterial composition containing compound K prepared thereby. In the present invention, various ginsenosides contained in g...
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WO/2019/224189A1 |
The present invention is related to an improved method for production of 7- dehydrocholesterol (7-DHC), an important intermediate towards biotechnological production of vitamin D3 or derivatives/metabolites thereof. The invention feature...
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WO/2019/224190A1 |
The present invention is related to an improved method for production of 7-dehydrocholesterol (7-DHC), an important intermediate towards biotechnological production of vitamin D3 or derivatives/metabolites thereof. The invention features...
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WO/2019/224188A1 |
The present invention is related to modified sterol acyltransferase enzymes with improved activity and/or specificity towards acylation of the vitamin D3 precursor 7-dehydrocholesterol (7-DHC) to be used in biotechnological production of...
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WO/2019/224187A1 |
The present invention is related to modified sterol acyltransferase enzymes with improved activity and/or specificity towards acylation of the vitamin D3 precursor 7-dehydrocholesterol (7-DHC) to be used in biotechnological production of...
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WO/2019/178980A1 |
A method for preparing gynostemma pentaphylla makino saponin LVI, XLVI, L, LI, Damulin A or Damulin B. In said method, Gynostemma cardiospermum Cogn.ex Oliv is used as a raw material to prepare a high content of target product by means o...
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WO/2019/169027A2 |
The present invention provides host cells and methods for making mogrol glycosides, including Mogroside V (Mog. V), Mogroside VI (Mog. VI), Iso-Mogroside V (Isomog. V), and glycosylation products that are minor products in Siraitia grosv...
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WO/2019/163601A1 |
The purpose of the present invention is to provide a transgenic plant in which 7-dehydrocholesterol, which is a precursor to active VD3, is produced in an increased amount, and a technique for using the same. This problem is solved by pr...
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WO/2019/136924A1 |
A method for promoting the suspension cell growth of momordica grosvenori and improving the content of mogroside V by means of salt stress, comprising: controlling the concentration of potassium ions to be 100-2,000 mg/kg in a process of...
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WO/2019/114157A1 |
Provided is a method for enzymatically converting and producing 9α-hydroxyandrost-4-ene-3,17-dione, the method comprising the steps of: expressing, in E. coli BL21, an oxidative subunit KshA, a reductive subunit KshB, and a subunit KshC...
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WO/2019/104608A1 |
Disclosed is a method for the enzyme catalysis synthesis of ginsenoside Rh2. The method produces ginsenoside Rh2 by using ginsenoside Rg3 as a substrate, and adding a glucosidase derived from Terrabacter ginsenosidimutans to perform a ca...
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WO/2019/078359A1 |
Provided is a method for producing a sterol. A sterol is produced by culturing a microorganism of the class Labyrinthulomycetes, which is capable of producing the sterol and has been modified so as to lower the activity of 24-dehydrochol...
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WO/2019/078410A1 |
The present invention relates to a method for preparing ginsenosides 20(S)-Rg3 or 20(S)-Rh2 by using a novel ginsenoside glycosidase, in order to obtain, with high efficiency, a highly pure ginsenoside 20(S)-Rg3 or 20(S)-Rh2. The prepara...
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WO/2019/017722A2 |
The present invention relates to a method for producing a ginsenoside from a Gynostemma pentaphyllum-derived adventitious root. Specifically, the present invention relates to a method for producing a ginsenoside from a Gynostemma pentaph...
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WO/2019/010971A1 |
A preparation method for dehydroepiandrosterone, comprising: in a protective atmosphere, adding potassium tert-butoxide to tert-butanol, stirring evenly, adding 4-androstenedione to obtain a mixture, and adding the mixture dropwise to a ...
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WO/2019/012095A1 |
The invention relates to ketoreductases and the use thereof. The ketoreductases of the invention are particularly useful for enzymatically catalyzing the reduction of ketones to chiral or non-chiral secondary alcohols and oxidation of ch...
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WO/2018/234479A2 |
The present invention relates to a method for preparing bile acid derivatives with a protected hydroxyl group in position 3, the method comprising the contacting of a bile acid derivative, having an unprotected 3-alpha-hydroxyl group, wi...
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WO/2018/227644A1 |
Provided is a method for catalyzing steroidal biological transformation. In the method, sodium alginate-grafted cyclodextrin immobilized cells are used as a catalyst, so as to implement the cyclic utilization of a cyclodextrin medium, th...
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WO/2018/227940A1 |
A method for preparing ursodeoxycholic acid via a chemical-enzymatic process, comprising: adding hyodeoxycholic acid to a first organic solvent, and oxidising under the effect of an oxidising agent to obtain 6-oxo-lithocholic acid; addin...
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WO/2018/210208A1 |
Provided are a glycosyltransferase, a mutant, and an in vitro glycosylation method. The method comprises the steps of: transferring a glycosyl group of a glycosyl donor to a hydroxyl group at the C-3 position of a tetracyclic triterpenoi...
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WO/2018/204483A2 |
Provided herein include methods of making mogroside compounds, e.g., Compound 1, compositions (for example host cells) for making the mogroside compounds, and the mogroside compounds made by the methods disclosed herein, and compositions...
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WO/2018/133844A1 |
The present invention provides a cytochrome P450 mutant protein and applications thereof. In particular, in the present invention, after the modification of key sites in the cytochrome P450 CYP716A47, the PPD production and the PPD/DM pr...
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WO/2018/126468A1 |
The present invention relates to a preparing method for an ursodesoxycholic acid by using a biological enzyme catalysis technology and 7β-hydroxysteroid dehydrogenase for preparation of the ursodesoxycholic acid. The method uses a 3α-h...
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WO/2018/126469A1 |
The present invention relates to a method for preparing ursodeoxycholic acid by using a biological enzyme catalysis technique and a 7β-steroid dehydrogenase for use in the preparation thereof. The method uses 3α-hydroxy-7 oxo-5β-chola...
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WO/2018/126466A1 |
The present invention relates to a method utilizing a biological enzyme catalysis technique for preparing 3α-hydroxy-7-oxo-5β-cholanoic acid and a 7α-steroid dehydrogenase for use in preparation thereof. The method uses chenodeoxychol...
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WO/2018/126467A1 |
A method which uses biological enzyme catalysis to prepare 3α-hydroxy-7-oxo-5β-cholanoic acid and 7α-steroid dehydrogenase for the preparation thereof. The method uses chenodeoxycholic acid as a substrate; in the presence of NAD, lact...
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WO/2018/120983A1 |
Provided are a Glycyrrhetinic acid-producing recombinant yeast strain, specifically the strain of deposit number CGMCC 13126, a preparation method for the strain, and uses of the strain in producing Glycyrrhetinic acid. The strain overex...
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WO/2018/062904A1 |
Disclosed are a composition for production of ginsenoside compound K using a high temperature-β-glycosidase and a high temperature-α-L-arabinofuranosidase, and a method for preparing ginsenoside compound k. The composition for producin...
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WO/2018/045946A1 |
A Poria cocos fermentation product. On the basis of the total weight of the Poria cocos fermentation product, the total amount of the following compounds (1) to (12) is no less than 0.15% by weight: (1) pachymic acid (PA), (2) dehydropac...
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WO/2018/036982A1 |
The invention relates to a further chemical-biocatalytic method for producing ursodeoxycholic acid from chenodeoxycholic acid after chemical oxidation to 3,7-diketo-ursodeoxycholic acid and after subsequent reaction with 7 beta-hydroxyst...
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WO/2018/028006A1 |
Provided are a mycobacterium neoaurum, a ketosteroid C27-monooxygenase derived from mycobacterium neoaurum, and application of the ketosteroid C27-monooxygenase. By adding expressions of SMO isoenzyme SMO1, SMO2 and/or SMO3 to mycobacter...
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WO/2018/012644A1 |
The present invention relates to a recombinant microorganism for producing a steviol glycoside and a method for producing a steviol glycoside. The recombinant microorganism for producing a steviol glycoside according to the present inven...
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WO/2017/220486A2 |
The present invention relates to a coupled biotransformation process of converting chenodeoxycholic acid (CDCA) and related compounds to ursodeoxycholic acid (UDCA) and related compounds. It also relates to the cloning, expression, and b...
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WO/2017/214919A1 |
Provided are mycobacterium genetically-engineered bacteria and applications thereof in the preparation of a steroidal compound. The mycobacterium genetically-engineered bacteria are mycobacteria lacking of all of acyl-CoA dehydrogenase f...
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WO/2017/150723A1 |
Algae that generates a sterol and a sterol production method that uses the algae. According to the present invention, a sterol is produced by culturing algae, such as strain AJ7867 (FERM BP-22304) and strains derived therefrom, that has ...
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WO/2017/119795A1 |
The present invention relates to a novel Lactobacillus casei GFC1 strain (deposit number: KFCC18333P), a fermented ginseng extract using the strain, and a preparation method thereof. When the novel Lactobacillus casei GFC1 strain (deposi...
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WO/2017/108799A1 |
The present invention is related to production of a sterol mix in a modified yeast cell, wherein the amount of zymosterol present in said mix is dramatically reduced or abolished via modification of sterol acyltransferase activity within...
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WO/2017/089408A1 |
The present invention relates to an enzymatic method for producing deconjugated bile acids from bile.
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WO/2017/075257A2 |
Disclosed herein are compounds having structural Formula (I), or salts thereof. These compounds are useful as sweet tasting agents and/or sweetness enhancers. Also disclosed are compositions comprising the present compounds and methods o...
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WO/2017/069565A1 |
The present invention relates to a method for selectively producing ginsenoside Rd, which is originally present in a trace amount in ginseng, from panaxadiol-based saponins in ginseng and, more specifically, to a method capable of obtain...
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WO/2017/069561A1 |
The present invention relates to a method for selectively producing ginsenoside F2, compound Mc, and compound O, which is originally present in ginseng in trace amounts, from saponins of ginseng and, more specifically, to a method capabl...
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WO/2017/069569A1 |
The present invention relates to a method for selectively producing compound K and compound Y, which are originally present in trace amounts in ginseng, from saponins of ginseng and, more specifically, to a method capable of obtaining de...
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WO/2017/057851A1 |
The present invention relates to a ginsenoside fatty acid ester compound, a method for preparing same, and a cosmetic composition comprising same and, more specifically, to a ginsenoside fatty acid ester compound, modified into a fatty a...
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WO/2017/057852A1 |
The present invention relates to a ginsenoside fatty acid ester compound, a method for preparing same, and a cosmetic composition comprising same and, more specifically, to a ginsenoside fatty acid ester compound, modified into a fatty a...
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WO/2017/020143A1 |
Provided is a method of biosynthesizing a functional lipid using a nano-magnetically immobilized enzyme for continuous targeted catalysis of a phospholipid in soybean oil, comprising: applying nano-magnetically immobilized phospholipid e...
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WO/2016/119756A1 |
Provided are a mutant protein of glycosyltransferase and uses thereof. Specifically, by using homology alignment and site-directed mutagenesis, a new mutant protein of glycosyltransferase is discovered. The mutant protein is a non-natura...
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WO/2016/090622A1 |
Provided are a hydroxyacyl-coenzyme A dehydrogenase gene and an acyl-coenzyme A thiolase gene, and a genetically-engineered bacteria and a use thereof. The hydroxyacyl-coenzyme A dehydrogenase gene encodes a protein (i) or (ii) as follow...
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WO/2016/066738A1 |
Generally, the present invention relates to the field of steroid hydroxylation. More specifically, the present invention relates to a method for the 21-hydroxylation of steroids in cells. It also relates to cells expressing a steroid 21-...
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WO/2016/064007A1 |
The present invention relates to: a method for producing rubusoside from stevioside by using a Lactobacillus plantarum strain, which is a type of Lactobacillus; a composition, to be used in the method, for producing rubusoside, containin...
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