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WO/2003/057680A1 |
A process for producing high−purity 2−cyanoimino−1,3−thiazolidine which comprises: a first step comprising reacting an alkali metal cyanide compound, an alkali metal hydroxide, and a lower alcohol with chlorine in an aqueous solu...
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WO2002030860A9 |
The present invention relates to novel ketone compounds, compositions comprising ketone compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism disorders c...
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WO/2003/011817A1 |
The present invention relates to 1,3,5-tricyano-2,4,6-tris(vinyl)benzene derivatives and method for preparing the same. The 1,3,5-tricyano-2,4,6-tris(vinyl)benzene derivatives can be prepared by refluxing 1,3,5-tricyanomesitylene with N-...
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WO/2003/000652A1 |
A process for the preparation of cyclohexanol derivatives of formula (I) by reacting a compound of formula (II) with a compound of formula (III) in the presence of a base catalyst of formula (IV) or (V). In the above formula, R¿1?-R¿9?...
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WO/2002/085843A2 |
The present invention relates to processes for the preparation of any of the intermediate 1,3-substituted indenes of formulae (Ia, Ib and Ic) or a mixture thereof, wherein R?1¿, R?2¿, R?3¿, R?4¿, and R?5¿ are defined herein. Compoun...
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WO/2002/064548A1 |
The invention relates to prepolymer compositions on the basis of Novolac cyanates of the general formula (I), wherein n is a number of from 0 to 20 and the groups R are the same or different and represent hydrogen or methyl. The inventiv...
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WO/2002/042258A1 |
N-protected-L-homocysteine disulfide of the formula (I) or an activated form thereof is reacted with (S)-2-amino-6,6-dimethoxyhexanoic acid, methyl ester to give the disulfide intermediate of the formula (II). The disulfide intermediate ...
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WO/2002/030863A2 |
The present invention relates to novel ether compounds, compositions comprising ether compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism disorders com...
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WO/2002/024613A2 |
The present invention relates to certain resorcinol derivatives and their use as skin lightening agents.
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WO/2001/056975A1 |
The invention concerns novel substituted imide derivatives of general formula (I), wherein R?1¿ represents optionally substituted cycloalkyl; R?2¿ represents optionally substituted alkyl or optionally substituted cycloalkyl; R?3¿ repr...
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WO/2001/010824A1 |
The invention relates to dicyanatochalcones of general formula (I), wherein R?1¿ to R?8¿, independent of one another, represent hydrogen, C¿1?-C¿4? alkyl, C¿1?-C¿4? alkoxy or halogen. The compounds can be produced from correspondin...
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WO/2001/000623A1 |
Method of producing compounds of formula (I), wherein R¿1? is hydrogen or C¿1?-C¿4?-alkyl; R¿2? is hydrogen, C¿1?-C¿8?-alkyl, C¿3?-C¿6?-cycloalkyl, or a radical -N(R¿3?)R¿4?; or R¿2? and R¿6? together are -CH¿2?-CH¿2?-S-; R...
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WO/2000/069813A1 |
The invention relates to novel substituted N-cyano amidines of general formula (I) in which: R?1¿ represents hydrogen or optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, aryl or alkyl aryl, and; R?2¿ represe...
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WO2000040547B1 |
Methods for stereoselective substitution in which a (mono or un)- alpha -substituted unprotected beta -amino ester compound or salt thereof is reacted with an aliphatic electrophile in the presence of a base selected from alkyl lithium c...
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WO/2000/055123A1 |
The present invention relates to novel aromatic cyanate ester compounds containing at least two rings linked by a group containing an unsaturated group. The present invention further relates to compositions and prepolymers of said novel ...
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WO/2000/014056A1 |
A process for producing efficiently an O-alkyl-N-cyanoimidate from cyanamide and an orthoacetate on an industrial scale by using an inexpensive device. In the production of an O-alkyl-N-cyanoimidate by reacting cyanamide with an orthoace...
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WO/2000/010970A1 |
The invention relates to new methoximinophenylacetic acid amides of formula (I), wherein R represents alkylthio, halogenalkylthio, optionally substituted arylthio, alkoxycarbonylthio, alkylthiocarbonyl, -S-Y, -S-N(R?1¿R?2¿), -CO-N(R?3Â...
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WO/2000/009477A1 |
The invention relates to unsaturated oligophenol cyanates of the general formula (I) [A-]¿n?[B-A-]¿x?B[-A]¿m?, in which A is a group of formula (II) and B is a group of formula (III), where R?1¿, R?2¿ and R?3¿ are each hydrogen or ...
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WO/2000/003976A1 |
The invention relates to novel imidamide derivatives of formula (I), wherein R, R?1¿, R?2¿ and R?3¿ have the meaning mentioned in the description. The invention also relates to a method of production and to the use of said derivatives...
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WO/1999/062867A1 |
Cardiac failure remedies containing as the active ingredient indan derivatives represented by general formula (I) or medicinally acceptable salts thereof, wherein R?1¿ is hydrogen, nitro, cyano, amino, C¿1?-C¿6? alkylcarbonylamino or ...
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WO/1999/028984A1 |
The invention concerns novel electrode materials derived from polyquinoid ionic compounds and their uses such as in electrochemical generators. It concerns in particular compounds such as a rhodizonic acid salt; a rufigallic acid salt; a...
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WO/1998/027055A1 |
This invention is directed to compounds of formula (I) wherein when a is 0, b is 1 or 2; when a is 1, b is 1, m is from 0-3, X is O or S, Y is halogeno, R�1? is hydrogen or C�1-4? alkyl, R�2? is hydrogen, C�1-4? alkyl, or optiona...
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WO/1998/023584A1 |
Arylcyanates are produced by reacting polyvalent phenols with a halogen cyanogen in the presence of a tertiary amin and a non-aqueoues solution at high temperature. The tertiary ammonium halogenide obtained as a secondary product is full...
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WO/1998/018755A1 |
The present invention provides novel oligomers comprising one alkenyl- and one cyanate-functional group of general formula (I) in which X is a group containing an alkenyl double bond and Y is an organic group with a molecular weight of u...
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WO/1998/000408A1 |
Compounds of the formula (I), in which -A- is a group (A�1?), (A�2?) or (A�3?) where the bonding of -A- to the nitrogen atom takes place via the carbon atom; R�1? is halogen, C�1?-C�4?alkyl, C�1?-C�4?haloalkyl, C�1?-Cï¿...
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WO/1997/024319A1 |
The invention relates to cyanimino oxime ethers of formula (I), in which X is NOCH3, CHOCH3, CHCH3; Y is O, NZ, where Z is H, alkyl; R1 is H, alkyl; R2 is cyano, nitro, trifluoromethyl, halogen, alkyl, alcoxy; m is 0, 1, 2, the radicals ...
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WO/1997/004881A1 |
A compound having the formula: (x(CH2=CR1-C(O)O-)R2-(O-C(O)R3)y-O-C(O)-NH)n-R4, wherein R1 is hydrogen or methyl, R2 is an alkylene group or substituted alkylene group (typically having less than six carbon atoms, more typically two or t...
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WO/1996/030329A1 |
The invention relates to substituted benzenes and derivatives thereof, useful as neuraminidase inhibitors, to pharmaceutical compositions comprising such compounds, and to methods of using these compounds for treating viral and other inf...
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WO/1996/025398A1 |
The invention relates to novel substituted heterocyclic compounds, several processes for their production and their use as fungicides, and novel intermediate products, several processes for their production and their use as fungicides.
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WO/1996/011415A2 |
The invention relates to polycyanate resin optical components with a refractive index at 633 nm in the range from 1.45 to 1.70 and an optical attenuation at 1.3 or 1.55 'mu'm of 0.1 to 1.0 dB/cm.
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WO/1996/007636A1 |
The invention pertains to new imidic acid derivatives of formula (I), methods for preparing them and their use as pesticides.
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WO/1995/024381A1 |
This invention relates to compounds of formula (I) which are useful as PDE IV inhibitors and for treating diseases related thereto.
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WO/1995/014467A1 |
The present invention provides N,N'-diaryl substituted guanidines having therapeutic utility. The compounds of the present invention are represented by formula (I), wherein R and R1 represent hydrogen or other group and Ar and Ar1 repres...
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WO/1995/005386A1 |
Substituted phenethylamines of formula (I) useful for treating phosphodiesterase IV related disease states are disclosed herein.
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WO/1995/000471A1 |
A compound represented by general formula (I) or a possible stereoisomer or optical isomer thereof, and a pharmaceutically acceptable salt thereof (wherein R1, R2, R3 and R4 represent each hydrogen, etc.; R6 and R7 represent each optiona...
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WO/1994/017035A1 |
New aminoacid derivates have the general formula: T-Z-NR1-(R2CR3)-CO-Y-(CH2)n-R, in which R, R1 to R3, T, Z, Y and n are defined as in the first claim. They represent valuable NPY-antagonistic active substances. Also disclosed are their ...
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WO/1994/015902A1 |
Compounds, compositions, and methods for modulating processes mediated by Retinoid X Receptors using retinoid-like compounds which have activity selective for members of the subclass of Retinoid X Receptors (RXRs), in preference to membe...
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WO/1994/013619A1 |
The invention concerns compounds of formula (I) in which n is 0 to 6; X represents halogen, CN, OCN, SCN, C2-C4 alkinyl or CHR5R6, R5 and R6, independently of each other, being CN, NO2, formyl, optionally halo-substituted (C1-C4 alkyl)ca...
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WO/1993/024564A1 |
Described is a flexible adhesive formulation for bonding a semiconductor device to a flexible substrate and a flexible card containing a semiconductor device which can be processed in a computer.
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WO/1993/016987A1 |
Described is a flexible adhesive formulation for bonding a semiconductor device (14), a flexible substrate and a flexible card containing a semiconductor device (14) which can be processed in a computer.
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WO/1993/016985A1 |
Cyano-oxime ethers of formula (I): R?1¿R?2¿CH-ON=C(CN)-R?3¿ in which R?1¿ is hydrogen or C¿1?-C¿4? alkyl, R?2¿ is a possibly substituted mono to tri-nuclear aliphatic or aromatic ring system which, besides carbon atoms, may contai...
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WO/1993/004032A1 |
A compound having a high insecticidal activity, represented by general formula (I), or a salt thereof wherein R¿1? represents optionally substituted alkyl; R¿2? represents hydrogen, optionally substituted alkyl or COR¿3? wherein R¿3?...
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WO/1993/001165A2 |
Compounds of formula (I) and salts and prodrugs thereof wherein, Q is optionally substituted phenyl, heteroaryl or naphthyl; X and Y are each H, C1-6 alkyl, C2-6 alkenyl or X and Y are together =O; Z is O or S; R1 is H, optionally substi...
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WO/1992/021651A1 |
Novel bis(3-propenyl-4-cyanatidophenyl) and bis(3,5-dipropenyl-4-cyanatidophenyl) compounds of respective general formula (I), in which A is H- or CH3-CH=CH-, X is -CH2-, -CR2-, -C(=O)-O-, -Y-, or -Z-(-Y-Z-)n, where R has 1-4 carbon atom...
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WO/1992/018467A1 |
The description relates to novel cyanophenoxynaphthyl oxycarboxylic acid derivatives of formula (I) in which R?1�, R?2�, R?3�, R?4� and R?5� have the meanings given in the specification and several processes and novel semi-fini...
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WO/1992/017025A2 |
Peptides which include unnatural amino acids and which inhibit the secretion of gonadotropins by the pituitary gland and inhibit the release of steroids by the gonads. The peptides are analogs of the decapeptide GnRH wherein there is at ...
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WO/1992/000273A1 |
Compounds of formula (I) and their salts in which R1 is optionally substituted phenyl, R2 is alkyl, cycloalkyl or optionally substituted amino, or R2 and R3 together with the nitrogen and carbon atoms to which they are attached form an o...
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WO/1991/017149A1 |
This invention relates to alkanoic acid compounds having a naphthyl ring and thio substituents which are useful as leukotriene antagonists.
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WO/1991/005761A1 |
A method of inhibiting the growth or replication of viruses of the HIV group is disclosed. Also disclosed are compounds useful in the method and pharmaceutical formulations incorporating such compounds. The method involves the use of com...
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WO/1991/004965A1 |
The present invention relates to a compound having formula (I) which has an excellent insecticidal activity, wherein R¿1? represents an optionally substituted 5-6 membered aromatic hetero ring containing nitrogen atom, except a non-subs...
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