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Matches 1 - 50 out of 7,556

Document Document Title
WO/2022/169729A1
A crosslinkable coating composition comprising: ingredient A that has at least two protons that can be activated to form a Michael carb anion donor, wherein ingredient A is selected from the group consisting of an acetoacetate group cont...  
WO/2022/165404A1
The invention relates to antiviral compounds, compositions comprising antiviral compounds, and methods of use. In particular, the antiviral compounds are cytidine triphosphate synthetase 1 (CTPS1) inhibitors that are effective in treatin...  
WO/2022/152109A2
Provided herein are lipid compounds that can be used in combination with other lipid components, such as neutral lipids, cholesterol and polymer conjugated lipids, to form lipid nanoparticles for delivery of therapeutic agents (e.g., nuc...  
WO/2022/150431A2
Described herein are the amphetamine-related compounds amphetamine carbamate (amphetammonium-amphetacarbamate) and amphetacarbamate, methods of making them, methods for detecting or quantitatively determining the amount of amphetacarbama...  
WO/2022/148585A1
The present invention relates to a method for producing materials having at least one carbamate functionality, to carbamate-functional materials obtained from the inventive process, coating compositions comprising said carbamate-function...  
WO/2022/145298A1
The present invention provides: a novel blocked isocyanate compound that can be produced at high yield; a compound having a low-temperature (at most 100ºC) crosslinkable double bond using said blocked isocyanate compound; and a resin ob...  
WO/2022/138891A1
The present invention addresses the problem of providing a method for producing a high-purity peptide compound with high efficiency and high yield. It is found that the problem can be solved by supporting a peptide on a resin for solid-p...  
WO/2022/138605A1
The present invention addresses the problem of providing a method for efficiently producing a peptide having a high purity, a reagent for forming a protective group having excellent deprotection properties, and a novel fused polycyclic c...  
WO/2022/136641A1
The present invention generally relates to the field of ionizable (also termed cationic) lipids, and in particular provides a novel type of such lipids as represented by formula (I). The present invention further provides methods for mak...  
WO/2022/134297A1
The present invention relates to a preparation method for a carboxylate ester compound, comprising: under the catalysis of a nitrite ester, reacting carboxylic acid and methanol in air, so as to obtain an ester compound. The preparation ...  
WO/2022/140269A1
Materials, methods, and systems for biorthogonal ligation of hydrogel labels to crosslinked-natural polymer hydrogels are provided. A heterobifunctional linker includes a peptide-reactive activated functional group on the heterobifunctio...  
WO/2022/132650A1
Described herein is a prodrug of a transient receptor potential vanilloid 1 receptor (TRPV1) agonist for the treatment of pain.  
WO/2022/132649A1
Provided herein are pharmaceutical formulations comprising a transient receptor potential vanilloid 1 receptor (TRPV1) agonist, or a pharmaceutically acceptable salt thereof.  
WO/2022/121317A1
Disclosed is a 1,1'-biphenyl-2,6-diphenolic compound and the use thereof. The 1,1'-biphenyl-2,6-diphenolic compound is a new compound, and has good biological activity. By means of in vitro tumor cell activity experiments, it was found t...  
WO/2022/117590A1
The invention relates to a compound of the general formula I wherein A is selected from the group consisting of an unbranched or branched alkyl group with 1 to 12 carbon atoms, a -R1-O-R2 group, a -R1- Si(R3R4R5) group, a -R1-O-Si(R3R4R5...  
WO/2022/112357A1
The present invention relates to a compound of the following formula (I) in particular for use in a method for preventing or treating a disease in an individual, more particularly for preventing or treating a disease is associated to pro...  
WO/2022/112868A1
The subject matter of the invention is a method for the preparation of oligocarbamates with a defined monomeric sequence of the general formula (I) characterised in that the multistage synthesis is performed in one reaction pot without t...  
WO/2022/108507A1
The present disclosure relates to an immobilized reagent comprising a moiety of formula I immobilized on a solid support (I) wherein –L– is a linker moiety; –R1 is selected from the group consisting of benzoyl, benzyl, naphthoyl or...  
WO/2022/104137A1
The disclosure provides recording materials including propane derivatized monomers and polymers for use in volume Bragg gratings, including, but not limited to, volume Bragg gratings for holography applications. Several structures are di...  
WO/2022/104113A1
The disclosure provides recording materials including mono- or poly-phenyl-core derivatized monomers and polymers for use in volume Bragg gratings, including, but not limited to, volume Bragg gratings for holography applications. Several...  
WO/2022/084834A1
The present invention concerns a novel process for preparing solriamfetol hydrochloride.  
WO/2022/052683A1
The present invention provides a method for preparing a water-soluble magnolol derivative and a honokiol derivative, methods for preparing intermediates of a water-soluble magnolol derivative and a honokiol derivative, and a related mono...  
WO/2022/048930A1
The invention relates to a process for producing isocyanates by reacting the corresponding amines with phosgene in the liquid phase, comprising: (a) mixing an amine comprising feed stream, a phosgene comprising feed stream and optionally...  
WO/2022/043374A1
The present invention relates to compounds of formula (II) wherein R1-R5, X and L are as described herein, and pharmaceutically acceptable salts thereof, compositions including the compounds and methods of using the compounds, particular...  
WO/2022/045824A1
The present invention relates to a phenyl alkyl carbamate compound for use in preventing or treating neurodegenerative diseases. The phenyl alkyl carbamate compound of the present invention, prevented dopaminergic neuron loss, attenuated...  
WO/2022/041171A1
The present application relates to a compound having the effects of being an antidepressant, narcotizing, alleviating pain, improving cognitive functions, protecting lungs, preventing or treating amyotrophic lateral sclerosis, or prevent...  
WO/2022/041502A1
Disclosed herein is a method for preparing 1,5-pentane diisocyanate, comprising the following steps: (1) mixing 1,5-pentanediamine, a carbonylation agent, a first solvent and a catalyst for a carbonylation reaction, performing solid-liqu...  
WO/2022/030606A1
A compound represented by general formula (I) or a salt thereof; a nerve growth promoter containing the compound or salt as the active ingredient; a medicinal composition containing the compound or salt; a therapeutic agent for neurodege...  
WO/2022/021859A1
Disclosed are a carisoprodol antigen, a preparation method therefor, and an application thereof. Carboxyl is derived from carisoprodol N by succinic anhydride; the carboxyl is coupled with a protein to obtain the carisoprodol antigen.  
WO/2022/023626A1
The invention relates to a rheology-modifying difunctional compound. The invention also provides an aqueous composition containing a difunctional compound according to the invention and a method for controlling the viscosity of an aqueou...  
WO/2022/020385A1
A dispenser comprising a dispensing device containing a dispensing device solution, the dispensing device solution comprising C20H29NO7Si, the dispensing device solution having antiviral properties and emitting or reflecting UV light, wh...  
WO/2021/250067A2
The present invention relates to a process for the purification of (R)-2-amino-3-phenylpropyl carbamate in perspective of the subsequent conversion in the corresponding HCl salt (SOLRIAMFETOL). The invention further relates to the proces...  
WO/2021/252640A1
The present disclosure relates to compounds of formulas (A) and (I), pharmaceutically acceptable salts thereof, and solvates of any of the foregoing, pharmaceutical compositions comprising the same, methods of preparing the same, interme...  
WO/2021/248770A1
A genetically encoded formaldehyde reactive unnatural amino acid. Specifically, the present invention relates to a genetically encoded formaldehyde reactive unnatural amino acid PrAK, a preparation method and an application thereof in de...  
WO/2021/246485A1
Provided is a carbamate production method characterized by bringing a carbon dioxide-containing mixed gas in which the partial pressure of carbon dioxide is 0.001 atm or greater but less than 1 atm, into contact with an amino group-conta...  
WO/2021/241557A1
A problem of the present invention is to provide a transfer film which can suppress corrosion in wiring and electrodes. Another problem of the present invention is to provide a method for manufacturing a laminate using the transfer film....  
WO/2021/231212A1
A foam forming composition is provided. The foam forming composition comprises, as an additive, a bis-carbamate compound, a bis-functional amide compound, or combination of two or more thereof. The compositions are suitable for producing...  
WO/2021/229331A1
Compound are described comprising a perfluorinated group bonded to at least one terminal photoinitiator group with an organic linking group comprising at least one amide moiety. The compound typically comprises the (e.g. Michael addition...  
WO/2021/223301A1
Provided is a preparation method for water-soluble Florfenicol amino acid ester salt, the method comprising the steps of: using Florfenicol and N-Cbz-amino acid as starting raw materials, and subjecting same to acyl chlorination, esterif...  
WO/2021/212762A1
A three-dimensional molding material, comprising the following components by mass fraction: 5-50% of a monofunctional polyurethane oligomer, 35-85% of a monofunctional monomer, 0-30% of a polyfunctional compound, 0.5-8% of a photoinitiat...  
WO/2021/217041A1
Disclosed are N-substituted α-amino and α-hydroxy carboxamides, pharmaceutical compositions comprising them, and methods of using them.  
WO/2021/217040A1
Disclosed are carbamate and urea derivatives, pharmaceutical compositions comprising them, and methods of using them.  
WO/2021/211436A1
The present application provides idebenone derivatives or analogues useful for treating a disease or disorder in a subject in need thereof. Pharmaceutical compositions comprising the compounds and methods of treating the disease or disor...  
WO/2021/209859A1
Monomers, polymers formed from such monomers, and articles for biomaterial capture including such polymers, wherein the monomer is represented by the following general Formula (I): CH2=CR1-C(=O)-X-R2-Z-X3-NR3-C(=X2)-X1-R4, wherein: R1 is...  
WO/2021/204175A1
Provided herein are lipids that can be used in combination with other lipid components, such as neutral lipids, cholesterol and polymer conjugated lipids, to form lipid nanoparticles for delivery of therapeutic agents (e.g., nucleic acid...  
WO/2021/207409A2
This invention is in the field of medicinal pharmacology. In particular, the present invention relates to pharmaceutical agents which function as inhibitors of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral replicatio...  
WO/2021/196323A1
The present invention provides a light-emitting layer material and a manufacturing method therefor, and an electroluminescent device. The light-emitting layer material comprises a spiral nanotube structure and light-emitting particles, a...  
WO/2021/195671A1
The present invention relates to a process for preparing trientine dihydrochloride as an active pharmaceutical ingredient (API). The present invention relates to a process for the preparation of trientine dihydrochloride with a pharmaceu...  
WO/2021/179049A1
The present invention relates to the treatment of disorders associated with oxidative stress including neuropathic pain and small synthetically derived compounds for treating such disorders.  
WO/2021/183542A1
Methods for making a dolastatin, auristatin or related compounds comprising the steps of providing a universal dolastatin core of Formula (I) reacting the C-terminal carboxylic acid group with an amine (A) to form an amide bond and react...  

Matches 1 - 50 out of 7,556