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WO/2024/042043A1 |
This invention relates to a synthetic method for the preparation of compound (1) and precursors thereof. Compound (1) is prepared via reaction of isoxazole (2) with phenylether (R)-3-ONa.
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WO/2024/013633A1 |
The present disclosure relates to the synthesis of Vitamin K2 bearing varying prenyl side chains. The synthesis comprises the reaction of phenyl sulfone of tert-butyl dimethyl silyl (TBDMS) protected mono prenyl menadiol with prenyl hali...
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WO/2024/002633A1 |
In a first aspect, the present invention provides a method for producing a compound of general formula (I) starting from methionine with an intermediate product of methionine sulfoxide. The method according to the present invention allow...
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WO/2023/200932A1 |
An active component carrier composition is disclosed comprising a mixture of one or more catalytically active components and one or more oxidized disulfide oil (ODSO) compounds, including a water-soluble fraction of ODSO. In certain embo...
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WO/2023/179072A1 |
Disclosed in the present invention are a garlic antibacterial mixture as well as a preparation method therefor and the use thereof. The preparation method comprises the following preparation steps: taking a garlic extract as a raw materi...
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WO/2023/151293A1 |
Disclosed in the present invention is a p-phenylcyclobutanamide rosemary compound and a preparation method therefor, and a use of the compound as a hyaluronidase inhibitor and an anti-aging beauty product. Specifically, disclosed in the ...
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WO/2023/027630A9 |
The present disclosure concerns a flow reactor and methods of fabricating the flow reactor thereof. The present invention also relates to reactions performable in the flow reactor. The flow reactor comprises inlet, an outlet, and a heter...
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WO/2023/137675A1 |
Disclosed in the present invention is the use of a nickel/ketone dual-catalysis system in a cross-coupling reaction of aryl halide and sodium arylsulfinate. Specifically, in a nitrogen atmosphere, aryl halide, sodium arylsulfinate, nicke...
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WO/2023/127855A1 |
The present disclosure provides a novel synthetic intermediate of prostaglandin or an optically active substance thereof, and a production method that uses the same. More specifically, in the method according to the present disclosure fo...
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WO/2023/090086A1 |
Provided are a secondary monohydrofluoroalkane selective adduct and a method for producing the same. A compound represented by formula (3) is produced by means of a method including a step for reacting a compound represented by formula (...
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WO/2023/079111A1 |
The present invention relates to method for converting a sulfide of the following formula (I), such as yperite: R1-S-R2 (I) wherein R1 and R2, identical or different, are a (C1-C3)alkyl, (C2-C3)alkenyl, aryl, aryl- (C1-C3)alkyl, or aryl-...
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WO/2023/065489A1 |
Provided are a high dielectric compound and a preparation method therefor, an epoxy high dielectric material and a preparation method therefor, and a semiconductor device. The high dielectric compound is represented by chemical formula (...
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WO/2023/061999A1 |
The present invention discloses a distinct mode of action of a nickel catalyst to forge C-0 bonds to unlock the mild utilization of N2O as O-atom transfer reagent in the synthesis of complex phenols from the corresponding aryl halides.
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WO/2023/040105A1 |
Disclosed is a preparation method for a green visible light-catalyzed acetate compound. In this method, an LED lamp is used as a light source to provide energy, economically available primary, secondary, and tertiary alcohols are used as...
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WO/2023/010390A1 |
Process for the production of phenol, said process comprising the steps of:(A) producing ethanol from a biomass, which is advantageously a carbohydrate-containing biomass, then(B) causing the ethanol produced at the step (A) to react wit...
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WO/2023/281536A1 |
The present invention relates to a process for the preparation of 2-nitro-4-methylsulfonyl benzoic acid of formula I. The present invention also relates to a process for the purification of 2-nitro-4-methylsulfonyl benzoic acid of formul...
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WO/2023/275677A1 |
The present disclosure relates to a process for the preparation of 2-nitro-4-methylsulfonyl benzoic acid (NMSBA). The process comprises reacting 1-chloro-2-nitro-4-methyl sulfonyl benzene (chloro NMSB) with a compound of Formula (II) by ...
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WO/2022/262597A1 |
The present invention provides a TNF-α small molecule inhibitor STU104, a preparation method therefor, and a use thereof. The absolute configuration of an optical isomer (R)-STU104 is identified, and in particular, it is found that STU1...
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WO/2022/239534A1 |
[Abstract] [Problem] The purpose of the present invention is to provide novel meta-ester aromatic diamines, a method for producing the same, and polyimide synthesis. [Solution] Provided are compounds represented by formula (1). In formul...
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WO/2022/202994A1 |
The present description discloses: a dried PRENCSO composition having improved storage stability; and a lachrymatory factor generation kit in which the dried PRENCSO composition is used. The dried PRENCSO composition according to the p...
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WO/2022/166848A1 |
Provided is a method for synthesizing (1R,2R)-AMPP and derivatives thereof by using an enzyme cascade reaction, comprising the following steps: step 1, using a benzaldehyde derivative as a substrate and an E. coli transketolase mutant as...
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WO/2022/166837A1 |
Disclosed are an aryl sulfide, a synthesis method therefor, and an application thereof. The aryl sulfide is a compound of the structure represented by formula I or an agriculturally acceptable salt thereof. The aryl sulfide and the agric...
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WO/2022/117604A1 |
The present invention relates to a method, a diagnostic system, a dopant and the use thereof for the enhancement of detection of an analyte of interest by Cross Spray ESI mass spectrometry. The dopant is preferably a sulfone. The method ...
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WO/2022/096682A1 |
The invention relates to a method of preparing arylvinylsulphones. The method comprises forming o a first reaction mixture comprising a catalyst complex of Cu(I)halide and a ligand, wherein the ligand is selected from mono-, bi- or polyd...
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WO/2022/092655A1 |
Disclosed is a method for preparing a thiomethylphenol derivative, the method comprising steps of: (a) performing a primary reaction of a phenol derivative represented by chemical formula 2, a mercaptan derivative represented by R4SH, an...
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WO/2022/083082A1 |
The present invention provides a method for preparing bicalutamide intermediate 2, comprising the following steps: dissolving N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methacrylamide in a lower fatty acid ester solvent, successively adding...
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WO/2022/055221A1 |
A polythiol composition according to exemplary embodiments includes at least two different polythiol-based compounds, and a peak area (%) of polythiol compound represented by C8H18S6 measured through a high performance liquid chromatogra...
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WO/2022/024094A1 |
The present disclosure provides a new and improved process for preparation of intermediate compounds and synthesis of mesotrione therefrom. The present disclosure provides an economical, efficient and eco-friendly process for preparation...
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WO/2022/012482A1 |
The present invention belongs to the field of organic synthesis, and particularly relates to a method for preparing a mesotrione herbicide. 4-methanesulfonyl-2-nitrobenzoic acid is used as a raw material, and is subjected to a chloroform...
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WO/2021/257922A1 |
The present disclosure pertains to new methods of performing a hydrodealkenylation of monounsaturated alcohols, thiols, and derivatives thereof, such as terpenes and derivatives, comprising ozonolysis and quenching using a sulfinic acid ...
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WO/2021/237371A1 |
The present application describes process for preparing an ortho-allylated hydroxy aryl compounds such as compounds of Formula (I) by reacting an allylic alcohol with a hydroxy aryl compound in the presence of aluminum compound selected ...
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WO/2021/223301A1 |
Provided is a preparation method for water-soluble Florfenicol amino acid ester salt, the method comprising the steps of: using Florfenicol and N-Cbz-amino acid as starting raw materials, and subjecting same to acyl chlorination, esterif...
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WO/2021/187215A1 |
In the present invention, a diphenylsulfone compound containing 4,4'-dihydroxydiphenylsulfone is produced at a good yield in a short time at a relatively low temperature. A diphenylsulfone compound represented by formula (2) is produced ...
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WO/2021/184649A1 |
The present invention relates to the technical field of chemosynthesis, and provides a method for preparing a florfenicol intermediate. The method comprises: under catalysis of a chiral catalyst, enabling p-methylthiobenzaldehyde to reac...
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WO/2021/181029A1 |
The present invention relates to a chemoenzymatic process for coproducing a disulfide and a sulfoxide or a sulfone from a composition M comprising: 1) a sulfide, 2) optionally an oxidizing agent, 3) an organic compound bearing at least o...
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WO/2021/174748A1 |
The present invention relates to a method for preparing a visible light catalyzed dichlorine addition product of an aliphatic olefin, comprising the following steps: using an aliphatic olefin as a substrate, using copper chloride having ...
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WO/2021/154143A1 |
The invention concerns a method for treatment of a stream of mixed compounds (4a) obtained from a process (3) comprising decomposition and/or conversion of a wood or pulp material, the method comprising: feeding the stream (4a-4e) throug...
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WO/2021/114424A1 |
Provided is a method for preparing a trifluorohydrocarbyl sulfone compound. The preparation method comprises continuously sending a trifluorohydrocarbyl thioether compound, sodium tungstate dihydrate and a hydrogen peroxide solution to a...
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WO/2021/107872A1 |
The present invention relates, in general terms, to methods of catalysing a reaction, including the steps of contacting a chemical entity comprising a sulphide moiety with a composite and an oxidant. The composite acts as a heterogeneous...
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WO/2021/104503A1 |
Disclosed is a method for preparing β-carbonyl sulfone. The method comprises: by taking an α-carbonyl diazo compound and sodium arylsulfinate as reaction substrates, cheap silver nitrate as an optimal catalyst, 1,10-phenanthroline as a...
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WO/2021/079617A1 |
The present invention provides: an amidite compound capable of improving the yield and purity of a polyoligonucleotide; a glycoside compound serving as an intermediate of the amidite compound; and a production method for a polynucleotide...
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WO/2021/071372A1 |
The invention relates to an improved process of vitamin K2 derivatives preparation via the alkylation of the menadione-cyclopentadiene adduct.
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WO/2021/060517A1 |
The present invention provides a novel method for producing a derivative of an organic substance that contains one or more groups selected from the group consisting of a sulfanyl group, a selanyl group and a sulfino group. A method for p...
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WO/2021/037683A1 |
The invention relates to a process for purifying 4,4'-dichlorodiphenyl sulfone comprising: (a) providing a suspension comprising particulate 4,4'-dichlorodiphenyl sulfone in carboxylic acid, (b) carrying out a solid-liquid separation of ...
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WO/2021/037677A1 |
The invention relates to a process for producing 4,4'-dichlorodiphenyl sulfone comprising reacting a solution comprising 4,4'-dichlorodiphenyl sulfoxide and at least one linear C6-C10 carboxylic acid as solvent with an oxidizing agent to...
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WO/2021/037672A1 |
The invention relates to a process for producing 4,4'-dichlorodiphenyl sulfone, comprising: (a) reacting 4,4'-dichlorodiphenyl sulfoxide and an oxidizing agent in at least one carboxylic acid as solvent to obtain a reaction mixture compr...
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WO/2021/037675A1 |
The invention relates to a process for producing 4,4'-dichlorodiphenyl sulfone, comprising: (I) reacting thionyl chloride, chlorobenzene and aluminum chloride forming an intermediate reaction product and hydrogen chloride; (II) mixing aq...
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WO/2021/037682A1 |
The invention relates to a process for purifying crude 4,4'-dichlorodiphenyl sulfone comprising: (a) dissolving the crude 4,4'-dichlorodiphenyl sulfone which may contain water in an organic solvent in which 4,4'-dichlorodiphenyl sulfone ...
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WO/2021/037680A1 |
The invention relates to a process for obtaining 4,4'-dichlorodiphenyl sulfone from an organic mixture comprising 4,4'-dichlorodiphenyl sulfone and a linear C6 to C10 carboxylic acid as organic solvent, comprising: (a) cooling the organi...
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WO/2021/036256A1 |
The present application is suitable for use in the technical field of drug synthesis, and provides a method for synthesizing an HIV protease inhibitor intermediate compounds. The method comprises subjecting compound 1a to an asymmetric t...
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