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JP4828822B2 |
The invention relates to compounds represented by Structural Formula I, which can bind to CCR9 receptors and block the binding of a ligand (e.g., TECK) to the receptors. The invention also relates to a method of inhibiting a function of ...
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JP4819847B2 |
Compounds having the active site of natural lipoxins, but a longer tissue half-life are disclosed. These small molecules are useful for treating vasoconstrictive, inflammatory, myeloid suppressive, cardiovascular, and gastrointestinal di...
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JP2011231103A |
To provide a novel method of producing a sulfur-containing amino acid without using hydrogen cyanide, sodium azide or the like for which handling takes caution as a raw material.The production method of a sulfur-containing amino acid com...
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JP4818798B2 |
The invention relates to compounds represented by Structural Formula I, which can bind to CCR9 receptors and block the binding of a ligand (e.g., TECK) to the receptors. The invention also relates to a method of inhibiting a function of ...
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JP4810762B2 |
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JP4808416B2 |
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JP4801266B2 |
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JP2011207793A |
To provide a method for safely and cheaply producing a dimercaptodiaryl sulfide compound giving a high refractive index to a resin for use in an organic optical material.There is disclosed a 4,4'-dithiodiarylsulfone compound represented ...
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JP2011207803A |
To provide a process for producing a haloalkyl sulfide efficiently by allowing an alkyl thiolate to react with a dihaloalkane.An alkyl thiolate is allowed to react with a dihaloalkane in the presence of a phase transfer catalyst to produ...
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JP4796671B2 |
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JP4798690B2 |
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JP4788154B2 |
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JP4784803B2 |
Phenylalanine derivatives of the following formula and analogues thereof have an antagonistic activity to alpha 4 beta 7 integrin and a selectivity toward alpha 4 beta 1 integrin. They are used as therapeutic agents for various diseases ...
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JP4785169B2 |
The present invention generally relates to methods of inhibiting ethylene responses in plants and plant materials, and particularly relates to methods of inhibiting various ethylene responses including plant maturation and degradation, b...
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JP4779099B2 |
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JP4774802B2 |
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JP4759828B2 |
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JP2011162562A |
To provide substituted di-, tri-, tetra-, and penta-sulfide compounds and compositions, and methods of using the same for the treatment and/or prevention of a cell proliferative disorder.The present invention also provides methods for pr...
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JP4751567B2 |
The present invention relates to an amide derivative of the formula (1), having a C5a receptor antagonistic action wherein each symbol is as defined in the specification. The above-mentioned amide derivative, an optically active form the...
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JP4743382B2 |
A medicament having inhibitory activity against NF- kappa B activation which comprises as an active ingredient a substance selected from the group consisting of a compound represented by the following general formula (I) and a pharmacolo...
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JP2011148815A |
To provide a beneficial medicine of compounds having biological activity equal to that of natural lipoxins, but a longer in vivo half-life, though the lipoxins are small molecules administerable in vivo to a plurality of diseases and con...
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JP4718123B2 |
The invention relates to a process of preparing disubstituted 9-alkylidenefluorenes and structure analoguous compounds, to novel compounds and intermediates prepared by this process, their use for the preparation of conjugated polymers a...
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JP4717350B2 |
Provided is a process for converting methane at a remote natural gas site into ethylene and other products. Methane is converted into syngas which is converted into a low-sulfur liquid hydrocarbon mixture containing less than 1 ppm sulfu...
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JP2011518765A |
New methods for producing difluoromethylene-containing compounds with phenylsulfur trifluoride or a primary alkyl-substituted phenylsulfur trifluoride are disclosed. Also, new methods for producing trifluoromethyl-containing compounds wi...
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JP2011126822A |
To provide a method for producing a polyhydric alcohol ester mixture of a mercaptocarboxylic acid, containing a partial ester and a complete ester of the polyhydric alcohol and the mercaptocarboxylic acid by reacting the mercaptocarboxyl...
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JP4713502B2 |
Preparation of tert-dodecylmercaptan by the reaction of hydrogen sulfide with tri-n-butene in the presence of a catalyst. An independent claim is also included for the use of the product.
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JP2011517669T |
The present invention relates to use of these compounds for the medicine containing the compounds which have compatibility to mu* opioid receptor and ORL1 receptor, those manufacturing methods, and these compounds, and medicine manufacture.
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JP4703563B2 |
A biologically active agent, wherein the agent is a compound of the formula: Wherein A, R5, R9, X, Q and n, m, q are defined herein below.
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JP4701372B2 |
A liquid crystalline sulfur compound exhibiting high anisotropic factor of dipolemoment is provided. A terphenyl skeleton sulfur compound expressed by the general formula (I) is provided. A compound is preferred wherein, in the general f...
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JP4704573B2 |
In one aspect, the invention provides ene-thiol elastomers comprising the reaction product of a polythiol free of hydrophilic groups and having at least two thiol groups and an aromatic, heterocyclic, aliphatic, or cycloaliphatic polyene...
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JP4704535B2 |
A novel catalyst (I) based on mixed oxides of zirconium (Zr) and M (where M is magnesium or alkaline earth metal), which contains 0.2-20 wt. % M, is prepared by coprecipitation form a solution from an aqueous solution of a Zr salt and an...
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JP2011515443T |
the present invention -- the [of the periodic table of the elements] -- have at least one complex of VIII vice-fellows' metal, and at least one compound of formula (I), Pn expresses プニコゲン in that case, and;W expresses the bridg...
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JP2011515326T |
In the present invention, it is related with a manufacturing method of a スルフィド compound using a スルフィド compound and an organic sulfur * indium complex. Therefore, in detail, the conventional synthetic method forms carb...
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JP2011515443A |
The present invention relates to a process for preparing aldehydes by reacting an α,β-unsaturated carboxylic acid or a salt thereof with carbon monoxide and hydrogen in the presence of a catalyst comprising at least one complex of a me...
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JP4684427B2 |
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JP4684426B2 |
To provide a method for efficiently producing in high yield a thiol compound useful as a polymerizable monomer for spectacle lens of high refractive index. This method for producing a thiol compound of the general formula III comprises r...
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JP4683801B2 |
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JPWO2009081483A1 |
An oxime ester compound of formula (I) useful as a photopolymerization initiator. A photopolymerization initiator having the oxime ester compound as an active ingredient is activated through efficient absorption of light of long waveleng...
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JP4637304B2 |
The present invention provides a compound containing at least one sulfhydryl group and at least one NO donor group, wherein said compound contains one or more protected sulfhydryl groups linked to at least one aromatic ring or a heteroar...
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JP2011504471A |
The invention relates to novel cyclic hydrocarbon compounds and derivatives thereof, processes for the preparation thereof, to said compounds for use as a medicament, to said compounds for use in therapy, to pharmaceutical compositions c...
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JP4625311B2 |
Compounds having the active site of natural lipoxins, but a longer tissue half-life are disclosed. These small molecules are useful for treating vasoconstrictive, inflammatory, myeloid suppressive, cardiovascular, and gastrointestinal di...
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JP4625310B2 |
Compounds having the active site of natural lipoxins, but a longer tissue half-life are disclosed. These small molecules are useful for treating vasoconstrictive, inflammatory, myeloid suppressive, cardiovascular, and gastrointestinal di...
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JP4618250B2 |
The present invention relates to a compound formula[I]: wherein X is bond, -CH2-, -O- or -NH-, R1 and R12 are each independently hydrogen, halogen, lower alkyl, etc., R2 is hydrogen or optionally substituted lower alkyl, R3 is hydrogen o...
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JP4619531B2 |
The invention provides novel PGF analogs. In particular, the present invention relates to compounds having a structure according to the following formula: wherein R1, R2, R3, R4, X, and Z are as defined. This invention also includes opti...
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JP4618845B2 |
The invention provides novel substituted phenylpropanoic acid derivatives that activate by binding to receptor as ligands of human peroxisome preliferant-activated receptor alpha (PPAR alpha ), and exhibit potent decreasing action on lip...
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JP2011501746A |
Provided herein are novel, stilbene like compounds of the general formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, metabolites, prodrugs, solvates, pharmaceutically acceptable salts and comp...
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JP4612219B2 |
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JP2011500619A |
The present invention refers to new NO-donors aspirin derivatives, a process for their preparation and pharmaceutical compositions containing them.
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JP2010285400A |
To provide a process for simply producing an aromatic thiol compound and/or an aromatic sulfide compound in a high yield.The process for producing an aromatic thiol compound represented by formula (2) and/or an aromatic sulfide compound ...
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JP4602671B2 |
The present invention relates to open chain alkoxyamine compounds, a polymerizable composition comprising a) at least one ethylenically unsaturated monomer and b) at least one open chain alkoxyamine compound. Further aspects of the prese...
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