| Document |
Document Title |
|
JP2009542626A |
The present invention relates to compounds of structural formula I as site-specific inhibitors of histone methyltransferase, where R1 and R1 is —OCH3 or —OH, R2 and R2 is —OH or —OAc; a process of isolating compound of structural...
|
|
JP4372752B2 |
The invention is a process for producing alkaline earth metal salicylates for use as lubricant detergents and to compositions prepared by the process. The process comprises two steps. Step 1 is the alkylation of salicylic acid is conduct...
|
|
JP4362666B2 |
|
|
JP4357964B2 |
A process for preparing particles of a substance comprising contacting a first formulation including a first substance with a first solvent stream and a second solvent stream, thereby causing formation of particles of the first substance...
|
|
JP2009242434A |
To provide a new orally active treating agent for effectively treating main defects including insulin resistance and pancreatic islet failure.The agent is useful for the treatment of various metabolic disorders, such as insulin resistanc...
|
|
JP2009536661A |
Catalytic compositions for conversion of substituted aromatic feed materials to oxidized products comprising aromatic carboxylic acid derivatives of the substituted aromatic feed materials comprise a combination comprising a palladium co...
|
|
JP2009536659A |
Methods of treating blood disorders are described.
|
|
JP2009536575A |
Catalytic compositions for conversion of substituted aromatic feed materials to oxidized products comprising aromatic carboxylic acid derivatives of the substituted aromatic feed materials comprise a combination comprising a palladium co...
|
|
JP4345319B2 |
|
|
JP4344817B2 |
|
|
JP4335607B2 |
The present invention provides a process for dehydrating hydrous sodium beta -naphtholate comprising: the step of heating the hydrous sodium beta -naphtholate or a mixture of the hydrous sodium beta -naphtholate and beta -naphthol which ...
|
|
JP4332347B2 |
Compositions that comprise, for one mole of o-iodoxybenzoic acid, from 0.5 to 4 molesof an aliphatic acid of formula CH3(CH2)nCOOH, in which n is from 8 to 20,of a benzenecarboxylic acid of formula in which R represents H, CH3, COOHor of...
|
|
JP4327085B2 |
A compound of formula (I) wherein R1 represents aryl optionally substituted by a heterocyclic group or a heterocyclic group optionally substituted by aryl wherein each aryl or heterocyclic group is optionally substituted; the group -(CH2...
|
|
JP2009531290A |
The present invention relates to new methoxylated aromatic compounds. It also relates to novel compositions comprising methoxylated aromatic compounds as well as to the use of these compositions as a medicament, in particular as a medica...
|
|
JP4295357B2 |
The invention provides a compound of the formula wherein X is S, O, NR' where R' is H or alkyl of 1 to 6 carbons, or X is ÄC(R1)2Ün where R1 is independently H or alkyl of 1 to 6 carbons, and n is an integer between 0 and 2; R2 is hydr...
|
|
JP4295361B2 |
Aryl-substituted and aryl and (3-oxo-1-propenyl)-substituted benzopyran, benzothiopyran, 1,2-dihydroquinoline, and 5,6-dihydronaphthalene derivatives have retinoid negative hormone and/or antagonist-like biological activities. The invent...
|
|
JP4282768B2 |
The present invention concerns a process for the preparation of a 4-hydroxybenzaldehyde and its derivatives. More particularly, the invention concerns the preparation of 3-methoxy-4-hydroxybenzaldehyde and 3-ethoxy-4-hydroxybenzaldehyde,...
|
|
JP4271259B2 |
A process is disclosed for dicarboxylating dihydric phenols, notably those where the hydroxyl groups are in the para or the ortho position vis-+E,gra a+EE -vis one another. More particularly, the invention pertains to a process for prepa...
|
|
JP2009114143A |
To provide an industrially-useful and eco-friendly new oxidation reaction.The process for producing a carboxylic acid from a primary alcohol uses an oxoammonium salt of formula (1) and uses an alkali metal chlorite as a co-oxidizing agent.
|
|
JP4268755B2 |
An oxygen scavenging agent and compositions capable of providing good oxygen absorption capabilities which contain said agent, wherein the agent is a modified anionic hydrotalcite particulate material.
|
|
JP4267037B2 |
|
|
JP2009102585A |
To provide a rubber vulcanizing compounding agent to improve the vulcanizing speed and the physical properties of vulcanized rubber.The rubber vulcanizing compounding agent contains an amino-alcohol salt compound of aromatic carboxylic a...
|
|
JP4263200B2 |
A method for making a compound of Formula I which is racemic or enantiomerically enriched at chiral center* comprising hydrogenating a compound of Formula V in the presence of a compound of Formula VII wherein: R 1 is F, Cl, or C 1 -C 3 ...
|
|
JP4258608B2 |
To provide an adsorbent material capable of selectively adsorbing a substance such as a gas, or a separating material with high separating performance. A metal complex composed of 2,5-dihydroxybenzoic acid, at least one metal atom select...
|
|
JP2009517456A |
Process for the obtaining of 1-adamantane (tricycle[3.3.1.1 (3,7)]decane) derivatives, or of a pharmaceutically acceptable salt thereof, based on a carboxylation reaction, via metallation, of a precursor compound with an adequate leaving...
|
|
JP2009517457A |
Process for the preparation of aromatic derivatives of 1-adamantane (tricyclo[3.3.1.1 (3,7)]decane), or an acceptable pharmaceutical salt thereof, based on a hydrolysis reaction of a precursor cyano compound. It also comprises different ...
|
|
JP2009516695A |
Triphenylethylene compounds of formula (I) are provided. The compounds are particularly useful for selective estrogen receptor modulation.
|
|
JP2009516694A |
Triphenylethylene compounds of formula (I) are provided. The compounds are particularly useful for selective estrogen receptor modulation.
|
|
JP2009515695A |
A reactor is described for conversion of chemical reactants comprising an oscillator with a number of perforated discs. The reactor is also suited to continuous conversion of reactants, and a method for such conversion is also described.
|
|
JP4251046B2 |
|
|
JP4251024B2 |
|
|
JP4249260B2 |
A first process involves the partial electrodialysis of a dialkali metal salt of an aromatic hydroxycarboxylic acid or a dicarboxylic acid to produce the approximate monoalkali metal salt and the alkali metal hydroxide. The monoalkali me...
|
|
JP2009513575A |
Compounds of formula I wherein R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as defined in the specification as a base or a pharmaceutically acceptable salt, solvate or solvate of salt thereof, processes for their preparation, new intermedia...
|
|
JP4239043B2 |
|
|
JPWO2007021001A1 |
In the present invention, in the general formula (1): in the formula, Y represents an iodine atom, a formyl group or an electrophilic species, and M represents a hydrogen atom or a metal atom. -Substituted benzoic acid compound and its m...
|
|
JP4228160B2 |
|
|
JP4231408B2 |
A catalyst of the invention includes an imide compound having a N-substituted cyclic imide skeleton represented by following Formula (I): wherein R is a hydroxyl-protecting group. Preferred R is a hydrolyzable protecting group. R may be ...
|
|
JP4223394B2 |
New, efficient methods for making novel platform molecules and polymerizable mesogens are provided, as well as the novel mesogens and methods of using same.
|
|
JP2009024007A |
To provide a method for preparing 4-[3-(dibutylamino)propoxy]benzoyl derivative, useful as an intermediate of dronedarone.The process for the preparation of 4-[3-(dibutylamino)propoxy]benzoyl chloride hydrochloride comprises (a) a step o...
|
|
JP2009501721A |
Disclosed herein are novel compounds with activity at RARbeta 2 receptors. Further disclosed are the use of such compounds for treatment of or to alleviate symptoms of cancer, neurological disorders such as memory deficits and schizophre...
|
|
JP2009501227A |
A method of making an aromatic dihydroxy diacid dihalide comprises forming a solution of an aromatic dihydroxy diacid in a solvent, contacting the aromatic dihydroxy diacid solution with a halogenating agent; heating the solution under a...
|
|
JP2009500358A |
New organic salts of strontium and methods of synthesizing such salts with high purity, high yields and with short processing times, at neutral conditions and at low reaction temperature, such as a temperature at or below 50° C.
|
|
JP4205671B2 |
A process is disclosed for the production of alkyl salicylic acids wherein the process comprises reacting salicylic acid with an olefin having at least four carbon atoms at elevated temperature in the presence of a perfluoroalkylsulfonic...
|
|
JP2008546809A |
A pleuromutilin in the form of a salt with salicylic acid, azelaic acid, sebacic acid or 2-[(2,6-dichlorophenyl)amino]benzeneacetic acid.
|
|
JP2008303221A |
To provide a photosensitive compound forming ultrafine photoresist patterns, and a photoresist composition containing the same.The photosensitive compound has a structure of chemical formula 1, as expressed by reaction process expression...
|
|
JP4191875B2 |
Disclosed is a producing method for a compound of formula (II), which comprises reacting a compound of formula (I) with CO2, in the presence of sodium t-butoxide, in an aprotic polar solvent, thereby introducing a carboxyl group at the 2...
|
|
JP4191508B2 |
An aromatic compound (C) is reacted with carbon monoxide (D) and molecular oxygen (E) in the presence of a palladium compound catalyst (A) and a catalyst (B) and thereby yields a aromatic carboxylic acid corresponding to the aromatic com...
|
|
JP2008540520A |
Compounds of formula I, wherein R1, Z, Y, M and R2 are as defined in the specification, pharmaceutically acceptable salts thereof, pharmaceutical composition containing the same, methods of using the same for therapeutic purposes and met...
|
|
JP2008280346A |
To make it possible to treat or prevent against toxicity induced in a mammal by a retinoid, vitamin A, and a vitamin A precursor, to prevent or alleviate harmful or undesirable side effects in treating a mammal with retinoids, to enhance...
|
|
JP4177810B2 |
A non-colorant hair treatment composition comprising a styling compound of formula (1); wherein n is any integer from 0 to 6, R1 is a H, OH, alkyl, alkoxide group or salts thereof; R2, R3, R4, R5 and R6 are independently selected from OH...
|
