| Document |
Document Title |
|
JP5907727B2 |
The invention relates to solids made of a porous crystalline metal-organic framework (MOF) loaded with at least one gas of biological interest, and to a method for preparing the same. The MOF solids of the present invention are capable o...
|
|
JP2016053055A |
To provide a prophylactic or therapeutic agent for diabetes, diabetic complications, diabetic microangiopathy complications, insulin resistance syndrome, metabolic syndrome, hyperglycemia, dyslipidemia, atherosclerosis, heart failure, ca...
|
|
JP5898230B2 |
The present invention is directed to novel substituted bicyclic aromatic compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
|
|
JP5898768B2 |
Described are compounds of the structural formula (I): Also provided are pharmacologically acceptable isomers and salts of the compound of (I). The compounds are useful in the treatment of inflammatory bowel disease.
|
|
JP5888230B2 |
|
|
JP5885591B2 |
|
|
JP5883794B2 |
Disclosed are compounds of formula: that inhibiting GPBP activity, making them useful as therapeutics in antibody-mediated disorders, drug-resistant cancer, inflammation, protein misfolding and ER stress-mediated disorders, and aberrant ...
|
|
JP5853957B2 |
Provided is a method for effectively producing a 4,5-dialkoxy-2-hydroxybenzoic acid from an inexpensive raw material. A method for producing a 2-bromo-4,5-dialkoxybenzoic acid represented by the following formula (2): (wherein each of R ...
|
|
JP5852469B2 |
A liquid crystal composition containing a liquid crystal molecule, a compound represented by the formula (1), and a compound represented by the formula (2) can provide a film with a reduced haze.
|
|
JP5845483B2 |
|
|
JP5843075B2 |
There is provided a novel intermediate for producing pesticides. A method for producing 1,3-bis(substituted phenyl)-3-substituted-3-hydroxypropan-1-one compound of Formula (3) comprises reacting an aromatic ketone compound of Formula (4)...
|
|
JP5826259B2 |
The present invention relates to the field of catalysis and, more particularly, to a ruthenium carbonate complex of formula [Ru(diene)(C03)] or [Ru(diene)(C03)2]Mn, wherein M is an alkaline (n is 2) or alkaline earth (n is 1) cation. The...
|
|
JP2015533856A |
Equation (I) [Chemical 1](In the formula, RfIs -CF3, -C2F5Or -CF2CFXCF3Is; X is -F or -OC3F7Is; Y is -H, -Cl or -Br; R is -OH,-(CH2)nOH,-(OCH2CH2)mOH,-(CH2)n(OCH2CH2)mOH, -OC (O) -R1,-(CH2)nOC (O) -R1,-(OCH2CH2)mOC (O) -R1, -C (O) NHw(CH...
|
|
JP5796872B2 |
The present invention provides salts and crystalline forms of the compound 5-chloro-N-((1-(4-(2-oxopyridin-1(2H)-yl)phenyl)-1H-imidazol
-4-yl)methyl)thiophene-2-carboxamide, and pharmaceutical compositions and method of use thereof.
|
|
JP5793020B2 |
|
|
JP2015168633A |
To provide a novel synthesis method in the production of a benzoic acid, which is an important compound for the synthesis of an organic compound, and an industrially suitable production method using main materials derived from nonfossil ...
|
|
JP5782331B2 |
|
|
JP5785045B2 |
To provide a debenzylation technology of efficiently hydrogenating a benzyl group as a protective group without decomposing or hydrogenating a halogen atom and an acyl group in an aromatic halide compound or an aromatic ketone compound.I...
|
|
JP2015157255A |
To provide a gas storage material having a superior retrievable amount of gas than the conventional ones.There is provided a gas storage material having: a metal organic structure having a metal cluster containing at least one kind of me...
|
|
JP5762327B2 |
The present invention provides a process for preparing 2,5-dihydroxyterephthalic acid which comprises reacting a dialkali metal salt of hydroquinone with carbon dioxide in a reaction medium in the presence of a potassium salt represented...
|
|
JP2015140332A |
To provide a metal complex, a metal complex solution, a method for producing a thin film, a thin film, an electronic element, a thin film transistor, a display device, an image sensor, and an x ray sensor, which enable easy preparation o...
|
|
JP5755029B2 |
|
|
JP5749248B2 |
A composition is described for topical application comprising, in a physiologically acceptable medium, at least one complex composed of a naphthoic acid derivative of formula (I), salts and esters thereof: and of at least one cyclodextri...
|
|
JP5739235B2 |
|
|
JP5735517B2 |
The present invention relates to a salt comprising an anionic pesticide and a cationic polyamine of the formula (A) or (B) as described in the description. The invention further relates to an agrochemical composition comprising said salt...
|
|
JP2015089884A |
To provide a method for producing lignin monomers with high yield by decomposing a plant material containing a lignin component such as wood using a reaction agent which is easily available and has no problem with handleability.There is ...
|
|
JP5705010B2 |
|
|
JP5702956B2 |
|
|
JP5698229B2 |
|
|
JP2015044829A |
To provide a compound having biaryl phosphodiesterase-4 (PDE4) inhibitory action useful for treatment and prevention of stroke, myocardial infraction and cardiovascular inflammatory diseases.There is provided a biaryl compound having at ...
|
|
JP5684585B2 |
The present invention relates to compounds which directly inhibit IRE-1± activity, and which are useful for treating diseases associated with the unfolded protein response and can be used as single agents or in combination therapies.
|
|
JP5679805B2 |
|
|
JP2015027954A |
To provide a metal complex having excellent gas adsorption performance, gas occlusion performance and gas separation performance.There is provided a metal complex which comprises a polycarboxylic acid compound, at least one metal ion sel...
|
|
JP5668452B2 |
|
|
JP5665350B2 |
|
|
JP5660037B2 |
A radiation-sensitive resin composition includes an acid-dissociable group-containing resin, and a compound shown by the following general formula (1). wherein Z− represents a monovalent anion shown by a general formula (2), M+ represe...
|
|
JP2015502391A |
The present invention in cosmetic compositions intended for anti-aging and / or depigmenting and / or anti-inflammatory and / or curative care products, the following formula I: (where n and m are equal to 0 or 1 , Where n + m = 1, R1 an...
|
|
JP5656186B2 |
The porous coordination polymer of the invention contains metal complexes formed by coordination bonding between a trivalent metal ion and an aromatic tricarboxylic acid represented by formula (1). The porous coordination polymer also ha...
|
|
JP5651291B2 |
To provide a simple method for producing a production intermediate of a polyethylene glycol derivative, and further to provide a large number of compounds useful as effective components of an antitumor agent by virtue of the method. A po...
|
|
JP5646789B2 |
An object of the present invention is to provide a porous polymer metal complex which can be used as a gas adsorbent and contains two or more types of similar ligands. A porous polymer metal complex is provided expressed by [CuX] n (1) (...
|
|
JP2014221775A |
To provide a method for preparing 5-haloalkyl-4,5-dihydroisoxazole derivatives represented by Formula 1, wherein Ris CHX, CX, CXCHXor CXCX; each X is independently Cl or F; Z is optionally substituted phenyl; and Q is phenyl or 1-naphtha...
|
|
JP2014193814A |
To provide a porous metal complex useful as a hydrogen storage material and excellent in storage stability.A porous metal complex has a pore structure formed by aggregating a plurality of metal complexes, each metal complex having a coor...
|
|
JP5603019B2 |
|
|
JP2014189538A |
To provide a porous metal complex having a sufficient capability of adsorbing a gas such as hydrogen and carbon dioxide.A porous metal complex has a pore structure formed by aggregating a plurality of metal complexes, each metal complex ...
|
|
JP5595047B2 |
|
|
JP5593303B2 |
The present invention relates to novel hydroxyl compounds, compositions comprising hydroxyl compounds, and methods useful for treating and preventing a variety of diseases and conditions such as, but not limited to aging, Alzheimer's Dis...
|
|
JP2014522384A |
The invention relates to substituted vinyl- and alkynylcyclohexenols of the general formula (I) and salts thereof where the R1, R2, R3, R4, R5, [X—Y] and Q radicals are each as defined in the description, to processes for preparation t...
|
|
JP5583739B2 |
A phthalic acid derivative represented by the general formula (1) has an inhibitory activity on metallo-ß-lactamase. Therefore, when used in combination with a ß-lactam antibiotic, the derivative can inhibit the deactivation of the ß-...
|
|
JP2014520104A |
Methods of producing organic materials such as petroleum materials and aromatic acids, phenols, and aliphatic poly-carboxylic acids using an oxidative hydrothermal dissolution (OHO) process are disclosed. The OHD method includes contacti...
|
|
JP5574669B2 |
|
