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JP2024508694A |
Bacteriophage lysin or bacteriophage in the manufacture of pharmaceuticals, cosmetics or therapeutic devices for the prevention, treatment or amelioration of acne or infections caused by Cutibacterium acnes or diseases associated with Cu...
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JP2024507934A |
Medical articles formed from polyurethane-based resins containing ionically charged modifiers provide enhanced properties. Polyurethane-based resins are the reaction product of components including diisocyanates; diol chain extenders; po...
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JP7433606B2 |
To provide a copolymer material that has excellent antithrombotic properties and achieves reduced effluent.A copolymer material comprises a repeating unit represented by the formula (1). When the weight of all the repeating units is 100 ...
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JP7431423B2 |
A first object of the present invention is to provide an antithrombotic cell adhesion sheet having excellent antithrombotic properties and cell adhesion properties. In addition, a second object of the present invention is to provide a me...
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JP2024505013A |
The present invention provides blood-compatible materials, implantable devices containing said materials, methods of preparing such materials, and medical devices coated therewith, as well as their use for antithrombotic and/or cell prol...
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JP7425609B2 |
Provided is a technology for exhibiting good antithrombogenicity.A polyurethane or polyurethane urea has a graft chain having a specific structure. Two functional groups included in the specific structure are each an alkyl group having 1...
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JP7414250B2 |
To provide an antithrombotic material containing a polymer that can inhibit the adhesion of platelets.The problem is solved by using a diene monomer represented by the formula (1) (where, R1 is a divalent saturated hydrocarbon group havi...
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JP7395153B2 |
To provide a novel antithrombotic material that has an excellent antithrombotic property.Provided is an antithrombotic material, which is an antithrombotic material containing a neutral acyl lipid, a phospholipid, and water, and in which...
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JP7375763B2 |
There is provided a copolymer for suppressing protein adsorption, which contains a constitutional unit (a) represented by Formula 1 and a constitutional unit (b) represented by Formula 2, and which is used for producing an article that c...
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JP7365830B2 |
To provide a medical instrument that has excellent slipperiness (particularly, puncture properties) and exhibits excellent antithrombotic properties.A medical instrument has, on its surface, a coating that has a mixture of silicone oil a...
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JP7365371B2 |
According to the invention there is provided inter alia a process for the manufacture of a solid object having a surface comprising a layered coating of cationic and anionic polymer wherein the outer coating layer comprises an anticoagul...
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JP2023153774A |
To provide a copolymer for inhibiting protein adhesion which prevents adhesion of protein and is suitable for manufacturing an article to be in contact with protein, a method for producing a copolymer, and a resin modifier, a molding mat...
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JP7353300B2 |
The present invention relates to an alloy for medical use, including Pt, Co, Cr, Ni, and Mo. The alloy includes 10 atom% or more and 30 atom% or less of Pt, 20 atom% or more and 31 atom% or less of Cr, 5 atom% or more and 24 atom% or les...
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JP2023540520A |
Various embodiments of the invention contained herein provide temporarily radiopaque liquid embolic compositions and methods used to embolize blood vessels and/or if desired. Provides controlled release of therapeutic agents. [Selection ...
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JP7346392B2 |
Disclosed are implantable heart valves having a surface modified to reduce the risk of thrombi formation post implantation into a subject. The prosthetic valve can include one or more leaflets comprising a base polymer admixed with an ol...
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JP2023126798A |
To provide a coated medical device that can prevent or reduce thrombus formation around a device and includes an expandable tubular body configured to be implantable in a lumen.A medical device includes an outer surface coupled to a poly...
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JP2023125798A |
To provide an embolic agent that has blood vessel embolization properties comparable to conventional embolic agents, but is excellent in injectability with a syringe and in stability and safety in vivo.The embolic agent is a copolymer of...
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JP2023537106A |
The present disclosure relates to stable formulations of tissue-type plasminogen activator (tPA). In particular, the present disclosure relates to certain novel agents, methods of making them, and methods of using them.
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JP7329384B2 |
To provide a structure regeneration substrate that allows three-dimensional structure regeneration.A structure regeneration substrate has a substrate composed of a bioabsorbable material, and a filament disposed like a brush on the subst...
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JP7313900B2 |
To provide an antithrombotic material comprising a polymer capable of preventing adhesion of platelet.An antithrombotic material comprises a polymer having a constitutional unit represented by at least one of the following formulas (1) a...
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JP7311983B2 |
To provide a production method of a gel film capable of suppressing deformation of the gel film due to partial peeling from a base material or wrinkles, and occurrence of failure such as cracking of the gel film.The production method of ...
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JP2023528825A |
The present invention relates to compounds for medical use in the treatment, prevention or diagnosis of arterial or venous thromboembolism.
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JP2023093620A |
To provide high strength biomedical materials and processes for making the same.Included in the disclosure are hydrophilic nanoporous solids that can be extruded with a high aspect ratio to make high strength medical catheters and other ...
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JP2023527365A |
The present disclosure provides vascular smooth muscle cell proliferation in subjects without ectonucleotide pyrophosphatase phosphodiesterase-1 (ENPP1) deficiency resulting in pathological disease of calcification or ossification by adm...
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JP2023527328A |
A structure having one or more surfaces configured for internal use within a patient's body, and a direct factor Xa inhibitor and a direct factor IIa disposed within or on the structure Devices, systems and methods are provided comprisin...
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JP7299162B2 |
Described are medical devices including expandable tubular bodies configured to be implanted into a lumen, wherein the outer surface of the expandable tubular bodies are coupled to a polymer(s).
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JP2023076322A |
To provide a new material having blood compatibility.A blood compatible material has, on its surface, peptides mainly composed of proline residues.SELECTED DRAWING: None
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JP7283808B2 |
The present invention relates to an artificial blood vessel comprising a shape-memory polymer, and a vascular anastomotic member formed of a shape-memory polymer. An artificial blood vessel according to an embodiment of the present inven...
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JP7277452B2 |
The present invention discloses a functionalized hyaluronic acid or a derivative thereof, as well as a process for the preparation thereof, and the use thereof as a biomaterial and as an ingredient in pharmaceutical compositions. The pre...
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JP2023519519A |
The present invention relates to a medical device (10), preferably a microrobot, applied inside the body, preferably inside the human body (2). Medical device (10) includes a body portion (11) and a tail portion (12). A control line (13)...
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JP7249290B2 |
A medical device substrate with a coating including a functional layer located on the substrate, with the functional layer including at least one sugar alcohol and being bonded to the substrate directly or indirectly via a functionalizat...
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JP7241034B2 |
Hollow fiber membranes in an oxygenator for an extracorporeal blood circulator are coated with an antithrombotic polymeric material. The porous hollow fiber membranes for gas exchange have outer surfaces, inner surfaces forming lumens, o...
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JP2023510889A |
The present invention provides bacteriophage means, namely intracorporeal bacteriophage means, nasopharyngeal and lung bacteriophage means, skin bacteriophage means and bacteriophage suture means, as well as two-syringe bacteriophage mea...
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JP2023026365A |
To provide a medical composition capable of imparting biocompatibility such as antithrombotic properties to a medical device surface or the like, and to provide its use.In one embodiment of the present invention, a medical composition co...
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JP2023507086A |
An antimicrobial amphiphilic hydrogel composition for use in wound hemostasis, comprising: a first crosslinkable amphiphilic component, wherein the first amphiphilic component is chemically crosslinked thereof; In a first crosslinkable s...
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JP7222963B2 |
There is described inter alia a device having a surface comprising a layered coating wherein the outer coating layer comprises a plurality of cationic hyperbranched polymer molecules characterized by having (i) a core moiety of molecular...
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JP7222049B2 |
A cardiovascular graft is provided with highly reduced thrombogenicity. The cardiovascular graft is an electrospun non-woven mesh produced from supramolecular polymers with large diameter fibers. The cardiovascular graft can be implement...
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JP2023021011A |
To provide an electrosurgical system for preventing reuse of instruments.An electrosurgical generator configured to generate electrical energy to be applied to biological tissue via electrical communication with an electrosurgical instru...
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JP2023017932A |
To provide a medical instrument or a base material coated with polydopamine bonded furthermore to a ligand such as an antibody and/or an antibody fragment.Polydopamine coating and a ligand may be bonded through a linker such as an organi...
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JP2023017012A |
To provide a medical device having a combination of drug eluting properties and thromboresistance.The device has a surface comprising a layered coating where the outer coating layer comprises a plurality of cationic hyperbranched polymer...
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JP2023503896A |
TECHNICAL FIELD The present invention relates to hydrogels of sulfhydryl-modified polymeric compounds, methods for preparing the same, and uses thereof. The present invention employs a novel structural sulfhydryl-modified polymeric compo...
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JP2023504137A |
A coating for medical devices is described. The coating comprises a surface layer and, optionally, a base layer, the surface layer comprising polymer chains attached to anti-coagulation groups, the anti-coagulation groups being sulfonic ...
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JP7209643B2 |
Provided is a medical coating material with which it is possible to form a continuous coating without exposing the substrate surface, especially on silicone rubber substrates. The medical coating material according to the present inventi...
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JP2022553294A |
The present invention relates to hydrophobic and hydrophilic coating compositions for medical devices or medical implants. The hydrophilic coating composition comprises a polymer soluble in water or a water-alcoholic solution, said polym...
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JP2022184212A |
To provide an absorbent article having improved absorbency of menstrual blood.There is provided an absorbent article having a functional substance, for absorbing menstrual blood. In the absorbent article, the functional substance has a f...
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JP7178120B2 |
The present invention relates to a photovulcanization application method together with 2nd type photo-initiator with single component which shows both initiator and thiol-en cross- binding characteristics for latex used in the production...
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JP2022167430A |
To provide a medical coating agent that has an antithrombotic ability and water-insolubility and also has high adhesion to a substrate, with little variation in the antithrombotic ability with time, leading to stable biocompatibility.A m...
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JP7158993B2 |
To develop a phosphorylcholine matrix having excellent biocompatibility as a novel blood compatibility coating material for a hollow fiber membrane for dialysis used in blood purification therapy in critical care or a medical substrate f...
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JP2022161408A |
To provide a storage container for blood or platelets that prevents a degradation of blood or platelets.A storage container for blood or platelets has a layer that contains a polymer having a constitutional unit derived from a monomer ha...
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JP2022159148A |
To provide a medical resin composition that has a proper water-droplet contact angle, based on fluorine, while avoiding excessive water repellency.A medical resin composition contains the following component (A) and the following compone...
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