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WO/1989/009626A1 |
An intravascular catheter comprising a cannula for insertion into a vascular system of a patient coated with hydrophilic polymer containing, in the polymer, an effective amount of polymyxin to prevent the growth of microorganisms is disc...
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WO/1989/009069A1 |
A medical material, an intermediate (polymeric material) therefor and a process for their production are disclosed. The medical material comprises a polymeric material having many epoxy groups bound to the functional groups of a polymer ...
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WO/1989/007521A1 |
Processes for treating polymeric surfaces to produce smooth, durable, slippery coatings which are able to withstand the rigors of sterilization and, long term exposure to human blood and other bodily fluids without substantial loss of th...
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WO/1989/007520A1 |
Processes for treating polymeric surfaces to produce smooth, durable, slippery coatings which are able to withstand the rigors of sterilization and, long term exposure to human blood and other bodily fluids without substantial loss of th...
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WO/1989/005616A1 |
Biomolecules are attached to supporting surfaces through the utilization of long chain chemical spacers, the spacers separating the surfaces and biomolecule groups by extended spacer lengths of at least 25 Angstroms. The spacers desirabl...
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WO/1989/004339A1 |
A fibroin molding is obtained by treating fibroin with a crosslinking or coupling agent such as carbodiimide or glutaraldehyde. This molding can be formed into any desired form such as cast film, regenerated fibers, permeable membrane, c...
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WO/1989/003851A1 |
A crosslinked polymer network comprising the reaction product of a polyethylene oxide and a polyglycidoxypropylsiloxane is described. These materials from hydrogel networks having very high partition coefficients for selected pharmaceuti...
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WO/1989/002282A1 |
The medical instrument of the present invention is used for depositing a surfactant which is safe to a living body onto part or the whole of a blood contacting portion of the medical instrument having the blood contacting portion made of...
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WO/1989/001791A1 |
Article exhibiting at least one surface of glass, metal or hydrophobic polymer coated with blood-compatible surface layer, in which the biocompatible surface layer consists of an adsorbed hydrophobized water-soluble polymer. Process for ...
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WO/1988/007872A1 |
A medical material which comprises a reaction product between a copolymer composed of a hydrophilic polymer moiety having epoxy groups and a hydrophobic polymer moiety having fluorinated side chains and a high-molecular compound having a...
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WO/1988/006602A1 |
A method for preparing hydroxamic acid polymers from primary amide polymers wherein polyvinyl monomers such as polyacrylamide are reacted with hydroxyl amine in aqueous solution at room temperature. The low reaction temperature is crucia...
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WO/1988/005302A1 |
A hemolysis inhibitor and plasticizer which comprises a triglyceride compound. A medical resin composition, a medical appliance, and a blood preservative containing this compound can prevent hemolysis of the blood in contact therewith by...
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WO/1988/004183A1 |
Antithrombotic medical materials and process for their production. The antithrombotic materials comprise a high-molecular compound having groups capable of reacting with an epoxy group, such as a hydroxy, amino, carboxyl or mercapto grou...
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WO/1988/003812A1 |
Medical implements which are substantially constituted by a soft vinyl chloride resin composition prepared by compounding 10 to 80 parts by weight of tri-n-alkyl trimellicate per 100 parts by weight of a vinyl chloride resin. The impleme...
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WO/1988/003814A1 |
A medical material showing a high and stable biocompatibility for a long time and a process for its production. The medical material comprises a base material composed of a polymer composed of repeating units having a functional group to...
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WO/1988/003813A1 |
Process for producing haemocompatible substrates by means of incorporation, adhesion and/or modification and anchoring of non-thrombogenic polysaccaride (HS I) with an endothelial cell surface, in its peptide-linked or free form, in and/...
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WO/1988/003027A1 |
A hemolysis inhibitor comprising a polycarboxylic acid ester, an ether compound and/or a monocarboxylic acid ester and a medical resin composition, medical implement, and blood-preserving fluid containing it. These compounds can prevent ...
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WO/1988/002623A1 |
The biocompatibility of biomaterials having solid surfaces is improved through coating the same with biocompatible agents. The method for modifying the solid surface to improve biocompatibility employs molecules of a biocompatible agent ...
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WO/1988/000956A1 |
A biocompatible polyester comprising repeating units derived from glycerophosphorylcholine or glycerophosphorylethanolamine and at least one di- or poly-functional acid or reactive derivative thereof is haemocompatible and may be used in...
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WO/1987/007156A1 |
An article adapted for applications where there are contacts with blood, especially medical applications, which article comprises a substrate coated with heparin or a heparin-based material. The novel feature in connection with the inven...
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WO/1987/006846A1 |
A non-thrombogenic surface is provided by forming a reservoir from which anticoagulant solution can permeate through a flexible wall (5, 6) of bio-compatible permeable material. Such reservoirs can be used in catheters one form of which ...
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WO/1987/006007A1 |
Immobilization of a physiologically active material while keeping the function of the physiologically active material on a high level, which is conducted by immobilizing the physiologically active material onto a carrier through an alkyl...
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WO/1987/005038A1 |
Polymer hydrogels are adapted for surgical implants by chemical modification of the surface to stimulate the attachment and growth of cells thereto. The modification may be by oxidative acid etching or by copolymerisation with methacryli...
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WO/1987/003608A1 |
New polyesters comprising polyoxyfluoroalkylene blocks are prepared by polycondensation of diols with dicarboxylic acids or with derivatives thereof, said fluorinated polyesters being characterized by such improved surface properties tha...
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WO/1987/003209A1 |
An anti-thrombogenic, elastic and uncalcifiable material is charaterized by the addition of fatty acid esters and possibly by the further addition of water-reactive cross-linking agents.
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WO/1987/002684A1 |
Plastics materials may be plasticised using lipids as the sole plasticiser or in combination with conventional plasticisers. When appropriate lipids are used thermosetting plastics and elastomers may be rendered biocompatible or therapeu...
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WO/1987/001040A1 |
An improved intraocular lens material which includes a polymer or glass substrate modified by a gas plasma deposition of a fluorocarbon coating producing a rigid, low-energy surface having significantly reduced cell damage with respect t...
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WO/1987/000060A1 |
Copolymer film deposited on a substrate comprising covalently fixed fragments of heparine having antithrombogenic properties. The polymer further comprises free carboxylic groups intended to neutralize free amine functions which are poss...
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WO/1986/007541A1 |
A composition which can impart an antithrombotic ability, which contains, as necessary ingredients, polyurethane or polyurethaneurea containing polytetramethylene oxide units in the main chain, a water-soluble and/or water-swellable poly...
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WO/1986/002933A1 |
A polyurethane reaction product of a di- or polyisocyanate and a diol or polyol having at least two hydroxyl groups capable of reacting with an isocyanate group and having the residue of at least one further hydroxyl group present in the...
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WO/1986/002087A1 |
A surface coated article comprising a substrate with a cured polyethylene oxide-based coating thereupon. The essential features of the article are that the coating essentially consists of polyethylene oxide chains, with one free end and ...
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WO/1985/005322A1 |
Polymeric materials characterized by hard segments and copolymer soft blocks comprising hydrophobic and hydrophilic components. The polymeric materials may be mixed with a base polymer and/or inorganic salts. The polymeric materials and ...
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WO/1985/003295A1 |
A compound of formula (I), in which X1 is a reactive group that can react to form a covalent bond with a reactive group on the surface of a material to be rendered biocompatible, X2 is a group -O- or a presursor of such a group, n is 2, ...
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WO/1985/001507A1 |
Use of hydrophilic surfaces in order to restrict the adhesion of bacteria on objects coming into contact with bacteria, such as objects within the food stuff industry, and within health care. The hydrophilic surface can be neutral or cha...
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WO/1985/000744A1 |
Synthetic material implant (1) particularly intended to be implanted in the human chest in order to form or remodel the breast of a woman, characterized in that the surface of the implant is coated with heparine (2).
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WO/1984/001892A1 |
The attachment and growth of endothelial cells on the luminal surface of a vascular prosthesis are enhanced by coating the luminal surface of the vascular prosthesis with peptide derived from elastin. The resultant vascular prosthesis, w...
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WO/1984/001286A1 |
Un conteneur de stockage des composants du sang est fabriqu� avec une composition de chlorure de polyvinyle plastifi� qui comprend un syst�me de stabilisation thermique s�lectionn� � partir du groupe constitu� de sels d'aci...
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WO/1984/000302A1 |
Biocompatible, highly antithrombogenic material for reconstructive surgery, which is based on poly(L-lactic acid) and/or poly(dL-lactic acid) and segmented polyester urethanes or polyether urethanes.
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WO/1983/003977A1 |
A process for providing a surface of glass, silicon, aluminium or silicone rubber of an article useful within medicine with a biocompatible surface layer. Said surface is reacted (after oxidation when required) with a silane containing a...
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WO/1983/003335A1 |
To prepare particularly bioprosthetic heart valves which are subject to calcification after the graft, the tissue is treated before the graft is effected with a quantity of hypophosphated solution which is efficient to reduce the calcifi...
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WO/1983/000695A1 |
Nonthrombogenic surfaces are formed from a polyurethane by end-capping an alpha, omega dihydroxy polyalkylene oxide with 1,4-transcyclohexane diisocyanate, which is then extended with a diamine or a short diol. Surfaces of body implants,...
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WO/1981/003277A1 |
Microfibrous heparin salts, nonwoven webs (22) of such fibers, a process for preparing the fibers and the use of the webs for the rapid heparinization of blood are disclosed.
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WO/1980/002378A1 |
A device for promoting endothelial cell motility and / or vascularisation in man and other vertebrate animals which comprises a carrier such as a sheet or tube of a plastic material, which carrier is impregnated or coated with a source o...
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WO/1979/000638A1 |
A method of treating surfaces of medical devices which are to be brought into contact with blood or blood plasma for the purpose of rendering the surfaces resistant to thrombosis. The surfaces are treated with a wetting solution of a sal...
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JP7457308B2 |
The present disclosure provides an antithrombogenic material having a substrate and a surface modified layer provided on at least a portion of the substrate, wherein: the surface modified layer includes a block copolymer having a first s...
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JP2024512271A |
A medical article formed from a polyurethane-based resin that includes an ionic charge modifier to enhance its properties. Polyurethane resins are the reaction product of components including diisocyanates, diol chain extenders, polyglyc...
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JP7448143B2 |
To provide a ε-polylysine ultrafine fiber that has a high ε-polylysine content while having practical physical properties, and a fiber structure comprising the same.An ultrafine fiber is composed of a polyamino acid containing ε-polyl...
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JP2024509972A |
The present invention relates to quaternized trimethylamine(quaternized trimethylamine)This invention relates to a method for grafting the surface of a medical device using the method. Quaternized trimethylamine(quaternized trimethylamin...
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JP2024509627A |
According to an exemplary embodiment of the invention, a composition for use in the treatment of urinary or fecal incontinence is provided that includes a nanostructured cellulosic material.
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JP2024508637A |
Described herein are compositions comprising: (i) a polysiloxane network; and (ii) a nitric oxide releasing material comprising a plurality of nitric oxide donating moieties covalently bonded to the polysiloxane network; and (b) a silico...
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