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JP6583682B2 |
To provide an industrial method for producing a cationic lipid, which does not require a special equipment and by which a cationic lipid of high purity can be efficiently obtained. A cationic lipid represented by formula (1) is mixed wit...
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JP6522094B2 |
The present disclosure relates to polymorphs of 4-[2-dimethylamino-1-(1-hydroxycyclohexyl)ethyl]phenyl 4-methylbenzoate hydrochloride, methods for preparing the same and use of the same.
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JP2019065016A |
To provide a design and a synthesis of a novel positively-charged prodrug of a retinoid of a general formula (31)' structure 31' or a retinoid-like compound.Positively charged amino groups of these prodrugs not only remarkably increase s...
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JP6496429B2 |
Disclosed are an acetylsalicylic acid derivative, i.e. a 2-(diethylamino)ethyl 2-acetoxy-benzoate hydrochloride crystal, and a preparation method and use thereof. The X-ray powder diffraction (XRPD) pattern of the crystal has characteris...
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JP6492564B2 |
To provide a liquid crystal aligning agent for obtaining a liquid crystal display element showing a good balance of various characteristics.The liquid crystal aligning agent comprises a polymer (P) obtained by a reaction using at least o...
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JP6494460B2 |
The invention provides a liquid softener composition providing a fragrance having high hydrophobicity as a free fragrance. The liquid softener composition improves dispersibility of a capsule fragrance and inhibits paint stripping.The so...
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JP6495654B2 |
The present application provides novel compounds and methods for preparing and using these compounds. These compounds are useful in treating pain, itch, overactive bladder and/or interstitial cystitis in patients by administering one or ...
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JP2019048887A |
To provide a novel compound for preparation.The present invention provides a compound of formula (X) (where Rand Rare H, predetermined alkyl or alkenyl, Rand Rare predetermined alkyl, alkenyl, or alkynyl, Land Lare a predetermined linkin...
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JP2019043890A |
To provide a compound having an excellent pest control action.A compound has a specific 3,5,6-trifluoro-2-amino-benzyloxycarbonyl cyclopropane structure.SELECTED DRAWING: None
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JP2019044140A |
To provide a wettability improver having excellent hydrophilicity addition effect even with a small amount of addition.There is provided a wettability improver containing an ion binding salt represented by the following chemical formula ...
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JP6482830B2 |
To provide a method for producing a high quality cationic surfactant in which smell and coloring are suppressed and which has excellent storage stability.A method for producing a cationic surfactant includes the following steps 1, 2, 3, ...
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JP6482829B2 |
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JP2018203776A |
To provide crystal modifications of DOTAP chloride excellent in stability, suitable for the preparation of pharmaceutical compositions.The present invention relates to crystal modifications of racemic (2R,S)- and enantiomerically pure (2...
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JP6434591B2 |
The present disclosure relates to polymorphs of 4-[2-dimethylamino-1-(1-hydroxycyclohexyl)ethyl]phenyl 4-methylbenzoate hydrochloride, methods for preparing the same and use of the same.
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JP6421862B2 |
A method of producing an epoxy compound, which comprises reacting hydrogen peroxide with a compound having a carbon-carbon double bond, in the presence of at least one of a tungsten compound and a molybdenum compound; and an onium salt c...
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JP6399111B2 |
A fluorine-containing ether monocarboxylic acid aminoalkyl ester represented by the general formula: €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒC n F 2n+1 O[CF(CF 3 )CF 2 O] a CF(CF 3 )COO(CH 2 ) b NR 1 R 2 (wherein R 1 is a hydrogen atom, ...
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JP6384863B2 |
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JP6372887B2 |
There can be provided an organic film composition for forming an organic film having dry etching resistance as well as advanced filling/planarizing characteristics.
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JP6370575B2 |
Cosmetic formulation comprises (a) 0.2-25 wt.% at least one esterquat compound (I), (b) 40-99.8 wt.% water, and optionally (c) 0-8 wt.% esterquat compounds (Ia). (I) amounts to at least 30 wt.%, based on all (I) and (Ia) present in the f...
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JP6367686B2 |
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JP6352950B2 |
This invention provides for a compound of formula (I):or a pharmaceutically acceptable salt thereof, wherein R1-R4, L and X are defined herein. The compounds of formula (I) and pharmaceutically acceptable salts thereof are cationic lipid...
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JP6347723B2 |
In a method for making a tris-(2-hydroxyethyl)-methylammonium methylsulfate fatty acid ester by quaternizing a tris-(2-hydroxyethyl)-amine fatty acid ester with dimethylsulfate the quaternizing is carried out in the presence of a solid a...
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JP6347298B2 |
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JP6320906B2 |
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JP2018510849A |
Disclosed are ester derivatives of sovetylom with enhanced CNS distribution.
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JP6290076B2 |
The present invention relates to crystal modifications of racemic (2R,S)- and enantiomerically pure (2R)-resp. (2S)-DOTAP chloride, to processes for the preparation thereof, and to the use thereof for the preparation of pharmaceutical co...
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JP2018030844A |
To provide a novel cationic lipid which allows nucleic acids to be easily introduced into cells, and a novel composition containing the cationic lipid.The present invention provides a cationic lipid, such as (3R,4R)-3,4-bis((9Z,12Z)-octa...
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JP6276763B2 |
The present invention provides a compound represented by the formula (Ia) as a novel cationic lipid that forms a lipid particle and also provides a lipid particle comprising the compound. The present invention further provides a nucleic ...
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JP2018016910A |
To provide a liquid softener composition which has both an excellent antistatic effect to a fiber product and freeze restorability.A liquid softener composition contains the following component (A), component (B) and component (C). The c...
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JP2018003187A |
To provide a liquid softener composition having consistent note perceived in all steps from cleaning a fiber product to wearing after a treatment, and capable of maintaining the flavor with the best strength.There is provided a liquid so...
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JP2017537088A |
The present invention relates to compounds of formulas I and II or pharmaceutically acceptable salts thereof, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. Pharmaceutical compositions containing an eff...
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JP6246234B2 |
This deals with a luminescent salt comprising a metal cluster anion and an organic cation, wherein the metal cluster anion comprises a metal cluster with at least two metal atoms, and ligands, the metal atoms being chosen from the group ...
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JP2017210494A |
To provide polymorphs of 4-[2-dimethylamino-1-(1-hydroxycyclohexyl)ethyl]phenyl 4-methylbenzoate hydrochloride, a manufacturing method therefor and a use thereof.There is provided a method for preparing a crystal of 4-[2-dimethylamino-1-...
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JP6240748B2 |
The present specification relates to a fullerene derivative, an organic solar cell including the same, and a fabricating method thereof.
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JP6236785B2 |
An arylamine compound including: a partial structure shown in formula (1-1) or (1-2), wherein either X or Y is one of leaving substituents and the other is a hydrogen atom; either (X1, X2) or (Y1, Y2) is one of the leaving substituents r...
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JP6234999B2 |
3,3-diphenylpropylamines of general formula (I), particularly Fesoterodine, as well as their enantiomers, solvates and salts, can be produced by treating a compound of formula (II) with a chiral alcohol to yield the diastereomeric esters...
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JPWO2016121370A1 |
To provide a technique capable of imparting flexibility while suppressing impaired water absorption of a textile product. A compound containing one compound represented by the general formula (1) or a mixture containing two or more compo...
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JP2017160261A |
To design and synthesize novel positively charged prodrugs of retinoids or retinoid-like compounds of the general formula (31), 'structure 31'.The positively charged amino groups of the prodrugs not only greatly increase the solubility o...
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JP6194957B2 |
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JP2017525723A |
The present invention relates to a process for producing alkanolamides, which reduces the "ripening" time and increases the ratio of diethanolamide to the ester in the final product. Further provided are additive compositions containing ...
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JP6175959B2 |
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JP6165621B2 |
Provided is a conductive composition for use in an electrophotographic apparatus and a conductive roll for use in an electrophotographic apparatus in which resistance reduction can be achieved even when an ion conductive agent is used. A...
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JP6158754B2 |
A quaternary ammonium salt compound is represented by the following formula (A-1), wherein, R1, R2, and R3 each represent an alkyl group, an alkenyl group, an aryl group, or an aralkyl group, a part or all of hydrogen atoms in these grou...
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JP6147432B2 |
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JP2017101343A |
To provide a liquid softener composition which can suppress generation of a foul smell derived from a cationic surfactant.The liquid softener composition comprises the following (A) and (B) components: (A) a cationic surfactant compositi...
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JP6143014B2 |
The present invention is at least one type of polymer selected from a polyimide precursor containing a structure expressed by the following formula [I] as a side chain and polyimide and polyamide that are obtained through the imidization...
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JP6132570B2 |
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JP6130701B2 |
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JP2017075166A |
To provide crystal modifications of DOTAP chloride with excellent safety, suitable for preparing pharmaceutical compositions.The present invention relates to crystal modifications of racemic (2R,S)- and enantiomerically pure (2R)- and (2...
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JP6117796B2 |
The invention relates to a process for recovery of noble products from heavy (meth)acrylic fractions generated during production of (meth)acrylic esters by transesterification, the heavy fractions comprising at least noble products and M...
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